TB-Profiler result

Run: ERR2513446
Summary

Run ID: ERR2513446

Sample name:

Date: 31-03-2023 19:41:03

Number of reads: 850101

Percentage reads mapped: 99.51

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.9
ccsA 619831 c.-60T>G upstream_gene_variant 0.33
rpoB 759620 c.-187A>C upstream_gene_variant 0.25
rpoB 759746 c.-61C>T upstream_gene_variant 0.9
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 0.97
rpoC 764359 c.990C>A synonymous_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.95
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416290 p.Gln353Arg missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471892 n.47G>A non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103225 c.-183A>C upstream_gene_variant 0.21
katG 2154724 p.Arg463Leu missense_variant 0.95
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168196 p.Leu806Pro missense_variant 0.13
PPE35 2170066 p.Ala183Thr missense_variant 0.38
PPE35 2170232 c.381T>A synonymous_variant 0.13
PPE35 2170238 c.375T>G synonymous_variant 0.13
PPE35 2170247 p.Ile122Met missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289692 c.-451C>G upstream_gene_variant 0.11
pncA 2290122 c.-882dupG upstream_gene_variant 0.17
eis 2715577 c.-245G>A upstream_gene_variant 0.2
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ribD 2987520 p.Val228Leu missense_variant 0.18
thyX 3067760 c.186G>A synonymous_variant 0.12
thyA 3073949 p.Pro175Ala missense_variant 0.1
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474927 c.921C>A synonymous_variant 0.11
Rv3236c 3612217 c.900C>T synonymous_variant 0.13
Rv3236c 3612839 p.Ala93Val missense_variant 0.17
alr 3841473 c.-53G>A upstream_gene_variant 1.0
panD 4044037 p.Gly82Val missense_variant 0.14
embC 4240171 c.309G>C synonymous_variant 0.12
embC 4242075 p.Arg738Gln missense_variant 1.0
embC 4242172 c.2310C>T synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242855 p.Gly998Val missense_variant 0.12
embA 4244184 p.Ser318Leu missense_variant 0.13
embA 4244966 c.1734C>A synonymous_variant 0.15
embB 4246816 c.303C>T synonymous_variant 0.13
embB 4248343 c.1830G>T synonymous_variant 0.14
aftB 4268808 p.Val10Ala missense_variant 0.11
ethA 4326406 c.1068C>T synonymous_variant 1.0
ethA 4326893 p.Leu194Gln missense_variant 0.15
ethA 4327139 p.Ala112Gly missense_variant 1.0
ethA 4327448 p.Ile9Thr missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0