TB-Profiler result

Run: ERR2513847
Summary

Run ID: ERR2513847

Sample name:

Date: 31-03-2023 19:56:44

Number of reads: 986805

Percentage reads mapped: 99.47

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 0.96
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 762752 c.-618G>T upstream_gene_variant 0.17
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.93
mmpL5 776047 p.Leu812Met missense_variant 0.1
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801158 p.Thr117Asn missense_variant 0.11
fbiC 1303557 c.627G>A synonymous_variant 1.0
fbiC 1303851 c.921C>T synonymous_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674391 p.Asp64Tyr missense_variant 0.11
rpsA 1834894 c.1353C>A synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918626 c.687G>A synonymous_variant 0.11
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 0.94
pncA 2289361 c.-120G>C upstream_gene_variant 0.11
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 0.97
pepQ 2860133 p.Gly96Cys missense_variant 0.18
ribD 2987498 c.660C>T synonymous_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339411 c.294T>C synonymous_variant 0.11
Rv3083 3449095 p.Gly198Ser missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474928 p.Gly308Ser missense_variant 0.11
fprA 3474997 p.Gly331Arg missense_variant 0.13
Rv3236c 3612486 p.Thr211Ala missense_variant 0.11
Rv3236c 3613105 c.12G>A synonymous_variant 0.12
alr 3841473 c.-53G>A upstream_gene_variant 0.93
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242947 p.Gly1029Arg missense_variant 0.1
embA 4243482 p.Ala84Thr missense_variant 0.11
embA 4243506 p.Thr92Ala missense_variant 0.17
embA 4243568 c.336C>T synonymous_variant 0.18
embA 4243625 c.393C>T synonymous_variant 0.12
embA 4243656 p.Trp142Arg missense_variant 0.12
embA 4244185 p.Ser318Asn missense_variant 0.13
embA 4244284 p.Pro351Gln missense_variant 0.12
embB 4249634 p.Asp1041Tyr missense_variant 0.12
aftB 4267623 p.Ser405Leu missense_variant 0.12
aftB 4267901 c.936G>T synonymous_variant 0.11
ubiA 4270004 c.-171G>T upstream_gene_variant 0.12
ethA 4328437 c.-964G>A upstream_gene_variant 0.13
ethA 4328445 c.-972A>C upstream_gene_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408272 c.-70C>T upstream_gene_variant 0.12