TB-Profiler result

Run: ERR2659166
Summary

Run ID: ERR2659166

Sample name:

Date: 31-03-2023 22:45:54

Number of reads: 1028498

Percentage reads mapped: 99.34

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5671 c.432C>T synonymous_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.97
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759851 c.45G>T synonymous_variant 0.44
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1304300 p.Gly457Asp missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473079 n.1234G>A non_coding_transcript_exon_variant 1.0
rrl 1474719 n.1062G>T non_coding_transcript_exon_variant 1.0
fabG1 1674076 p.Thr213Pro missense_variant 0.31
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156056 p.Gly19Val missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168316 p.Thr766Asn missense_variant 0.95
PPE35 2168460 p.Asn718Ser missense_variant 1.0
PPE35 2169281 c.1332T>G synonymous_variant 0.13
PPE35 2169902 c.711G>C synonymous_variant 0.12
PPE35 2170392 p.Gly74Ala missense_variant 0.14
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518764 p.Ser217Leu missense_variant 0.22
kasA 2518809 p.Lys232Arg missense_variant 0.18
eis 2715572 c.-240A>G upstream_gene_variant 0.33
folC 2746274 p.Val442Ala missense_variant 0.13
folC 2746572 p.Arg343Cys missense_variant 1.0
folC 2747788 c.-190C>T upstream_gene_variant 1.0
thyA 3074633 c.-162C>A upstream_gene_variant 0.13
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474123 c.117G>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3642013 p.Gln160Arg missense_variant 0.15
fbiB 3642711 p.Leu393Met missense_variant 0.15
rpoA 3878512 c.-6_-5insGAA upstream_gene_variant 1.0
ddn 3987111 p.Leu90Val missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241327 p.Arg489Cys missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4244341 p.Ser370Phe missense_variant 0.14
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4249460 p.Pro983Ala missense_variant 1.0
embB 4249705 c.3192G>A synonymous_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0