TB-Profiler result

Run: ERR4816103
Summary

Run ID: ERR4816103

Sample name:

Date: 01-04-2023 14:14:29

Number of reads: 1257663

Percentage reads mapped: 97.87

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777189 p.Tyr431Cys missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.25
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.4
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.4
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.29
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.29
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.22
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.33
rrs 1472666 n.821G>A non_coding_transcript_exon_variant 0.22
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.29
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.25
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.38
rrs 1472677 n.832C>G non_coding_transcript_exon_variant 0.29
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.29
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.29
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.29
rrs 1472694 n.849C>T non_coding_transcript_exon_variant 0.38
rrs 1472697 n.852T>G non_coding_transcript_exon_variant 0.29
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.22
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.33
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.22
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.2
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.17
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.23
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 0.14
rrs 1473093 n.1248C>A non_coding_transcript_exon_variant 0.15
rrs 1473099 n.1254T>C non_coding_transcript_exon_variant 0.15
rrs 1473102 n.1257C>G non_coding_transcript_exon_variant 0.15
rrs 1473107 n.1262G>C non_coding_transcript_exon_variant 0.15
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.25
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.25
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.25
rrs 1473116 n.1271A>G non_coding_transcript_exon_variant 0.18
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.27
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.2
rrs 1473127 n.1282G>A non_coding_transcript_exon_variant 0.18
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.21
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.23
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.21
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.2
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.17
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.13
rrs 1473193 n.1348G>A non_coding_transcript_exon_variant 0.12
rrs 1473204 n.1359C>T non_coding_transcript_exon_variant 0.12
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.12
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.11
rrl 1476160 n.2507delA non_coding_transcript_exon_variant 0.22
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 0.12
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 0.12
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.12
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2222980 p.Ala62Val missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641465 p.Leu308Pro missense_variant 0.56
alr 3841473 c.-53G>A upstream_gene_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0