TB-Profiler result

Run: ERR4819068
Summary

Run ID: ERR4819068

Sample name:

Date: 01-04-2023 15:54:25

Number of reads: 674576

Percentage reads mapped: 78.41

Strain: lineage4.1;lineage1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 0.43
lineage4.1 Euro-American T;X;H None 0.43
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 0.24
gyrB 6124 c.885C>T synonymous_variant 0.22
gyrA 6676 c.-626T>G upstream_gene_variant 0.17
gyrA 6700 c.-602T>C upstream_gene_variant 0.15
gyrA 6730 c.-572A>G upstream_gene_variant 0.17
gyrA 6745 c.-557T>G upstream_gene_variant 0.23
gyrA 6760 c.-542G>C upstream_gene_variant 0.31
gyrA 6763 c.-539G>C upstream_gene_variant 0.15
gyrA 6778 c.-524C>T upstream_gene_variant 0.23
gyrA 6793 c.-509T>C upstream_gene_variant 0.29
gyrB 6797 p.Gly520Thr missense_variant 0.31
gyrA 6824 c.-478C>T upstream_gene_variant 0.21
gyrA 6841 c.-461T>C upstream_gene_variant 0.2
gyrA 6853 c.-449A>G upstream_gene_variant 0.13
gyrA 7033 c.-269G>C upstream_gene_variant 0.16
gyrA 7099 c.-203G>A upstream_gene_variant 0.18
gyrA 7108 c.-194G>A upstream_gene_variant 0.25
gyrA 7114 c.-188C>A upstream_gene_variant 0.33
gyrB 7124 p.Ser629Thr missense_variant 0.29
gyrA 7132 c.-170T>G upstream_gene_variant 0.29
gyrA 7141 c.-161T>C upstream_gene_variant 0.29
gyrA 7165 c.-137C>G upstream_gene_variant 0.33
gyrA 7178 c.-124T>C upstream_gene_variant 0.33
gyrA 7361 c.60C>T synonymous_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7391 c.90C>T synonymous_variant 0.14
gyrA 7394 c.93T>C synonymous_variant 0.14
gyrA 7406 c.105G>C synonymous_variant 0.13
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8069 c.768T>C synonymous_variant 0.12
gyrA 8078 c.777A>G synonymous_variant 0.13
gyrA 8090 c.789C>A synonymous_variant 0.13
gyrA 8096 c.795T>A synonymous_variant 0.13
gyrA 8099 c.798T>C synonymous_variant 0.13
gyrA 8129 c.828T>C synonymous_variant 0.2
gyrA 8135 c.834C>G synonymous_variant 0.21
gyrA 8156 c.855T>C synonymous_variant 0.22
gyrA 8168 c.867A>G synonymous_variant 0.19
gyrA 8177 c.876A>C synonymous_variant 0.19
gyrA 8189 c.888G>C synonymous_variant 0.25
gyrA 8198 c.897T>C synonymous_variant 0.21
gyrA 8207 c.906T>C synonymous_variant 0.14
gyrA 8219 c.918T>C synonymous_variant 0.13
gyrA 8225 c.924T>C synonymous_variant 0.12
gyrA 8435 c.1134C>G synonymous_variant 0.24
gyrA 8452 p.Ala384Val missense_variant 0.27
gyrA 8852 c.1551T>C synonymous_variant 0.2
gyrA 8870 c.1569G>C synonymous_variant 0.15
gyrA 8897 c.1596T>C synonymous_variant 0.17
gyrA 8903 c.1602T>C synonymous_variant 0.13
gyrA 8966 c.1665C>G synonymous_variant 0.15
gyrA 8967 p.Ala556Arg missense_variant 0.15
gyrA 8987 c.1686C>A synonymous_variant 0.13
gyrA 8990 c.1689C>G synonymous_variant 0.12
gyrA 9143 c.1842T>C synonymous_variant 0.18
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490782 c.-1G>C upstream_gene_variant 0.12
fgd1 490797 c.15G>A synonymous_variant 0.17
fgd1 490800 c.18A>C synonymous_variant 0.18
fgd1 490803 c.21T>A synonymous_variant 0.18
fgd1 490812 c.30A>G synonymous_variant 0.18
fgd1 490815 c.33G>C synonymous_variant 0.2
fgd1 490827 c.45C>T synonymous_variant 0.14
fgd1 490848 c.66A>G synonymous_variant 0.16
fgd1 490851 c.69A>T synonymous_variant 0.16
fgd1 490868 p.Ala29Gly missense_variant 0.13
fgd1 491151 c.369G>A synonymous_variant 0.22
fgd1 491173 c.391C>A synonymous_variant 0.17
fgd1 491181 c.399T>C synonymous_variant 0.2
fgd1 491184 c.402A>G synonymous_variant 0.2
fgd1 491191 p.Gly137Arg missense_variant 0.2
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.22
fgd1 491202 c.420G>C synonymous_variant 0.25
fgd1 491203 p.Gln141Glu missense_variant 0.25
fgd1 491212 p.Ser144Arg missense_variant 0.25
fgd1 491217 c.435T>C synonymous_variant 0.25
fgd1 491742 c.960T>C synonymous_variant 0.62
mshA 575376 p.Ser10Leu missense_variant 0.29
mshA 575756 c.409C>T synonymous_variant 0.13
mshA 575770 c.423G>A synonymous_variant 0.17
mshA 575771 p.Val142Ser missense_variant 0.15
mshA 575821 c.474G>C synonymous_variant 0.2
mshA 575824 c.477T>G synonymous_variant 0.2
mshA 575884 c.537G>C synonymous_variant 0.26
mshA 575887 c.540G>C synonymous_variant 0.2
mshA 575893 c.546C>G synonymous_variant 0.24
mshA 575896 c.549G>C synonymous_variant 0.19
mshA 575908 c.561A>G synonymous_variant 0.22
mshA 575917 p.Asp190Glu missense_variant 0.2
mshA 575920 c.573C>G synonymous_variant 0.2
mshA 575924 p.Gly193Ser missense_variant 0.2
mshA 575944 c.597T>C synonymous_variant 0.18
mshA 576293 p.Ala316Ser missense_variant 0.17
rpoB 760142 c.336C>G synonymous_variant 0.12
rpoB 760181 c.375T>C synonymous_variant 0.16
rpoB 760184 c.378A>G synonymous_variant 0.2
rpoB 760196 c.390C>G synonymous_variant 0.21
rpoB 760223 c.417T>C synonymous_variant 0.2
rpoB 760235 c.429T>C synonymous_variant 0.21
rpoB 760376 p.Asp190Glu missense_variant 0.13
rpoB 760382 c.576G>C synonymous_variant 0.15
rpoB 760406 c.600G>C synonymous_variant 0.29
rpoB 760407 p.Ser201Gly missense_variant 0.14
rpoB 760412 c.606C>G synonymous_variant 0.15
rpoB 760415 c.609C>T synonymous_variant 0.19
rpoB 760430 c.624T>C synonymous_variant 0.27
rpoB 760433 c.627C>T synonymous_variant 0.14
rpoB 760454 c.648C>G synonymous_variant 0.15
rpoB 760457 c.651C>T synonymous_variant 0.15
rpoB 760469 c.663C>T synonymous_variant 0.15
rpoB 760475 c.669A>G synonymous_variant 0.29
rpoB 760478 c.672C>T synonymous_variant 0.14
rpoB 760484 c.678A>G synonymous_variant 0.13
rpoB 760670 c.864G>C synonymous_variant 0.33
rpoB 760674 c.868T>C synonymous_variant 0.4
rpoB 760679 c.873A>G synonymous_variant 0.29
rpoB 760683 c.877T>C synonymous_variant 0.29
rpoB 760721 c.915C>G synonymous_variant 0.29
rpoB 760730 c.924T>C synonymous_variant 0.29
rpoB 760817 c.1011A>G synonymous_variant 0.25
rpoB 760820 c.1014T>C synonymous_variant 0.38
rpoB 760826 c.1020C>G synonymous_variant 0.43
rpoB 760830 c.1024T>C synonymous_variant 0.38
rpoB 760841 c.1035T>C synonymous_variant 0.29
rpoB 760858 p.Val351Ala missense_variant 0.22
rpoB 760862 c.1056G>C synonymous_variant 0.33
rpoB 760869 p.Val355Leu missense_variant 0.25
rpoB 760877 c.1071G>C synonymous_variant 0.22
rpoB 760883 c.1077G>C synonymous_variant 0.18
rpoB 760886 c.1080A>G synonymous_variant 0.25
rpoB 760887 p.Thr361Val missense_variant 0.17
rpoB 760910 c.1104C>T synonymous_variant 0.17
rpoB 761180 c.1374A>C synonymous_variant 0.15
rpoB 761189 c.1383T>C synonymous_variant 0.18
rpoB 761195 c.1389G>C synonymous_variant 0.18
rpoB 761207 c.1401C>T synonymous_variant 0.2
rpoB 761213 c.1407G>C synonymous_variant 0.18
rpoB 761219 c.1413G>C synonymous_variant 0.2
rpoB 761492 c.1686G>C synonymous_variant 0.14
rpoB 761537 c.1731C>G synonymous_variant 0.19
rpoB 761573 c.1767C>G synonymous_variant 0.14
rpoB 761579 c.1773G>C synonymous_variant 0.14
rpoB 761612 c.1806G>C synonymous_variant 0.13
rpoB 761615 c.1809A>C synonymous_variant 0.14
rpoB 761948 c.2142G>C synonymous_variant 0.15
rpoB 761969 c.2163G>A synonymous_variant 0.13
rpoB 762149 c.2343G>C synonymous_variant 0.15
rpoB 762246 c.2440C>T synonymous_variant 0.18
rpoB 762266 c.2460T>C synonymous_variant 0.16
rpoB 762284 c.2478G>C synonymous_variant 0.16
rpoB 762293 c.2487T>C synonymous_variant 0.16
rpoB 762317 c.2511A>G synonymous_variant 0.16
rpoC 762449 c.-921C>A upstream_gene_variant 0.14
rpoC 762467 c.-903C>T upstream_gene_variant 0.18
rpoC 762488 c.-882G>C upstream_gene_variant 0.25
rpoB 762489 p.Val895Gln missense_variant 0.25
rpoC 762509 c.-861T>G upstream_gene_variant 0.29
rpoB 762510 p.Ala902Pro missense_variant 0.29
rpoC 762521 c.-849C>T upstream_gene_variant 0.2
rpoC 762818 c.-552C>G upstream_gene_variant 0.15
rpoC 762827 c.-543G>C upstream_gene_variant 0.17
rpoC 762983 c.-387C>T upstream_gene_variant 0.13
rpoC 762989 c.-381G>A upstream_gene_variant 0.13
rpoC 763031 c.-339T>C upstream_gene_variant 0.45
rpoC 763034 c.-336C>A upstream_gene_variant 0.15
rpoC 763040 c.-330C>G upstream_gene_variant 0.2
rpoC 763070 c.-300T>C upstream_gene_variant 0.18
rpoC 763528 c.159G>A synonymous_variant 0.38
rpoC 763531 c.162G>T synonymous_variant 0.12
rpoC 763546 c.177A>G synonymous_variant 0.31
rpoC 763570 c.201G>C synonymous_variant 0.31
rpoC 763573 c.204G>C synonymous_variant 0.15
rpoC 763594 c.225C>T synonymous_variant 0.21
rpoC 763603 c.234C>T synonymous_variant 0.12
rpoC 763636 c.267T>C synonymous_variant 0.14
rpoC 763660 c.291T>G synonymous_variant 0.14
rpoC 763675 c.306C>G synonymous_variant 0.14
rpoC 763884 p.Ala172Val missense_variant 0.78
rpoC 763886 c.517C>A synonymous_variant 0.88
rpoC 764405 c.1036A>C synonymous_variant 0.22
rpoC 764428 c.1059G>C synonymous_variant 0.18
rpoC 764431 c.1062G>C synonymous_variant 0.27
rpoC 764434 c.1065A>G synonymous_variant 0.27
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.18
rpoC 764458 c.1089G>C synonymous_variant 0.33
rpoC 764461 c.1092A>G synonymous_variant 0.3
rpoC 764497 c.1128A>G synonymous_variant 0.2
rpoC 764566 c.1197C>G synonymous_variant 0.22
rpoC 764575 c.1206T>G synonymous_variant 0.22
rpoC 764581 c.1212T>C synonymous_variant 0.2
rpoC 764593 c.1224C>T synonymous_variant 0.33
rpoC 764602 c.1233C>T synonymous_variant 0.15
rpoC 764611 c.1242G>T synonymous_variant 0.38
rpoC 764626 c.1257C>T synonymous_variant 0.15
rpoC 764632 c.1263T>C synonymous_variant 0.13
rpoC 764635 c.1266C>T synonymous_variant 0.12
rpoC 764650 c.1281G>C synonymous_variant 0.17
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.14
rpoC 764713 c.1344G>T synonymous_variant 0.21
rpoC 764746 c.1377G>T synonymous_variant 0.13
rpoC 764752 c.1383G>C synonymous_variant 0.27
rpoC 764758 c.1389C>G synonymous_variant 0.13
rpoC 764764 c.1395T>C synonymous_variant 0.33
rpoC 764815 c.1446A>G synonymous_variant 0.19
rpoC 764827 c.1458G>C synonymous_variant 0.21
rpoC 764858 c.1489T>C synonymous_variant 0.14
rpoC 764911 c.1542A>G synonymous_variant 0.18
rpoC 764932 c.1563C>A synonymous_variant 0.14
rpoC 764935 c.1566T>C synonymous_variant 0.15
rpoC 764948 c.1579T>C synonymous_variant 0.19
rpoC 764968 c.1599T>C synonymous_variant 0.16
rpoC 764995 c.1626C>G synonymous_variant 0.16
rpoC 765019 c.1650A>G synonymous_variant 0.15
rpoC 765150 p.Gly594Glu missense_variant 0.5
rpoC 765171 p.Pro601Leu missense_variant 0.47
rpoC 765292 c.1923G>C synonymous_variant 0.15
rpoC 765298 c.1929G>C synonymous_variant 0.14
rpoC 765300 p.Val644Ala missense_variant 0.17
rpoC 765319 c.1950A>G synonymous_variant 0.14
rpoC 765326 p.His653Ala missense_variant 0.14
rpoC 765329 p.Ser654Gly missense_variant 0.14
rpoC 765346 c.1977C>G synonymous_variant 0.25
rpoC 765349 c.1980T>C synonymous_variant 0.25
rpoC 765352 c.1983G>C synonymous_variant 0.21
rpoC 765404 p.Leu679Val missense_variant 0.14
rpoC 765409 c.2040T>C synonymous_variant 0.14
rpoC 765421 c.2052C>G synonymous_variant 0.19
rpoC 765478 c.2109T>C synonymous_variant 0.16
rpoC 765499 c.2130C>G synonymous_variant 0.19
rpoC 765529 c.2160C>T synonymous_variant 0.15
rpoC 765553 c.2184C>T synonymous_variant 0.15
rpoC 765556 c.2187G>C synonymous_variant 0.15
rpoC 766280 p.Ser971Gly missense_variant 0.15
rpoC 766288 c.2919C>G synonymous_variant 0.13
rpoC 766348 c.2979A>G synonymous_variant 0.15
rpoC 766357 c.2988C>T synonymous_variant 0.15
rpoC 766363 c.2994G>C synonymous_variant 0.16
rpoC 766381 c.3012C>T synonymous_variant 0.12
rpoC 766426 c.3057C>T synonymous_variant 0.17
rpoC 766447 c.3078T>C synonymous_variant 0.17
rpoC 766483 c.3114G>C synonymous_variant 0.17
rpoC 766484 p.Val1039Ile missense_variant 0.17
rpoC 766492 c.3123T>C synonymous_variant 0.25
rpoC 766522 c.3153C>G synonymous_variant 0.15
rpoC 766528 c.3159T>C synonymous_variant 0.14
rpoC 766540 p.Asp1057Glu missense_variant 0.13
rpoC 766607 p.Ile1080Leu missense_variant 0.21
rpoC 766630 c.3261G>C synonymous_variant 0.22
rpoC 766657 c.3288A>G synonymous_variant 0.33
rpoC 766660 c.3291G>C synonymous_variant 0.29
rpoC 766672 c.3303T>C synonymous_variant 0.32
rpoC 766673 p.Gly1102Asn missense_variant 0.26
rpoC 766726 c.3357T>C synonymous_variant 0.14
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.17
rpoC 766801 c.3432C>G synonymous_variant 0.25
rpoC 766804 c.3435A>G synonymous_variant 0.25
rpoC 766861 c.3492G>C synonymous_variant 0.29
rpoC 766864 c.3495G>C synonymous_variant 0.36
rpoC 766876 c.3507C>T synonymous_variant 0.3
rpoC 766882 c.3513C>T synonymous_variant 0.27
rpoC 766933 c.3564A>G synonymous_variant 0.25
rpoC 766945 c.3576A>G synonymous_variant 0.23
rpoC 766963 c.3594T>C synonymous_variant 0.18
rpoC 766972 c.3603G>C synonymous_variant 0.18
rpoC 766996 c.3627C>T synonymous_variant 0.2
rpoC 767230 c.3861G>C synonymous_variant 0.17
rpoC 767233 c.3864T>C synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.36
mmpL5 777085 p.Asn466Asp missense_variant 0.16
mmpL5 777095 c.1386T>C synonymous_variant 0.18
mmpL5 777101 c.1380C>G synonymous_variant 0.2
mmpL5 777110 c.1371T>G synonymous_variant 0.21
mmpL5 777115 p.Met456Leu missense_variant 0.23
mmpL5 777116 c.1365C>T synonymous_variant 0.23
mmpL5 777133 p.Val450Ile missense_variant 0.27
mmpL5 777158 c.1323C>G synonymous_variant 0.67
mmpL5 777164 c.1317C>G synonymous_variant 0.5
mmpL5 777170 c.1311T>C synonymous_variant 0.45
mmpL5 777176 p.Glu435Asp missense_variant 0.36
mmpL5 777191 c.1290C>G synonymous_variant 0.25
mmpL5 777194 c.1287A>G synonymous_variant 0.25
mmpL5 777206 c.1275A>G synonymous_variant 0.21
mmpL5 777212 p.Ala423Thr missense_variant 0.2
mmpL5 777215 c.1266C>G synonymous_variant 0.2
mmpL5 777218 c.1263G>A synonymous_variant 0.21
mmpL5 777251 c.1230C>G synonymous_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781421 c.-139C>A upstream_gene_variant 0.54
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781841 c.282C>G synonymous_variant 0.14
rpsL 781868 c.309T>C synonymous_variant 0.18
rpsL 781871 c.312G>C synonymous_variant 0.19
rpsL 781892 c.333A>G synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.18
fbiC 1303836 c.906G>C synonymous_variant 0.14
fbiC 1303845 c.915C>G synonymous_variant 0.18
fbiC 1303846 p.Phe306Val missense_variant 0.18
fbiC 1303854 c.924T>C synonymous_variant 0.18
fbiC 1303860 c.930A>C synonymous_variant 0.22
fbiC 1303884 c.954T>G synonymous_variant 0.25
fbiC 1303905 c.975G>C synonymous_variant 0.25
fbiC 1304610 c.1680C>T synonymous_variant 0.26
fbiC 1304739 c.1809C>T synonymous_variant 0.13
fbiC 1304742 c.1812T>C synonymous_variant 0.19
fbiC 1304757 c.1827A>G synonymous_variant 0.24
fbiC 1304778 c.1848T>C synonymous_variant 0.26
fbiC 1304784 c.1854T>C synonymous_variant 0.26
fbiC 1304787 c.1857T>G synonymous_variant 0.26
fbiC 1304808 c.1878C>G synonymous_variant 0.21
fbiC 1304811 c.1881C>G synonymous_variant 0.25
fbiC 1304817 c.1887T>C synonymous_variant 0.27
fbiC 1304829 c.1899T>C synonymous_variant 0.5
fbiC 1304832 c.1902C>T synonymous_variant 0.5
fbiC 1304856 c.1926C>G synonymous_variant 0.4
fbiC 1304862 c.1932G>A synonymous_variant 0.29
fbiC 1304883 p.Glu651Asp missense_variant 0.17
fbiC 1304891 p.Ile654Thr missense_variant 0.15
fbiC 1304893 p.Gly655Ser missense_variant 0.15
embR 1417019 p.Cys110Tyr missense_variant 0.3
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.17
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.14
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.23
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.15
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.18
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.18
rrl 1473660 n.3G>A non_coding_transcript_exon_variant 0.44
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.18
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.29
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.2
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.25
fabG1 1673329 c.-111A>G upstream_gene_variant 0.14
inhA 1674660 c.459G>C synonymous_variant 0.14
rpsA 1833589 c.48A>T synonymous_variant 0.21
rpsA 1833595 c.54T>C synonymous_variant 0.19
rpsA 1833721 c.180A>G synonymous_variant 0.14
rpsA 1833724 c.183C>G synonymous_variant 0.13
rpsA 1833727 c.186G>C synonymous_variant 0.13
rpsA 1833748 c.207C>G synonymous_variant 0.18
rpsA 1833787 c.246C>G synonymous_variant 0.17
rpsA 1833790 c.249T>C synonymous_variant 0.21
rpsA 1833802 c.261A>G synonymous_variant 0.2
rpsA 1833811 c.270G>T synonymous_variant 0.18
rpsA 1833838 c.297G>C synonymous_variant 0.18
rpsA 1833841 c.300C>G synonymous_variant 0.2
rpsA 1833847 c.306C>G synonymous_variant 0.16
rpsA 1833856 c.315A>G synonymous_variant 0.17
rpsA 1833874 c.333T>C synonymous_variant 0.18
rpsA 1833886 c.345C>G synonymous_variant 0.17
rpsA 1833979 c.438T>C synonymous_variant 0.15
rpsA 1834000 c.459G>C synonymous_variant 0.29
rpsA 1834009 c.468C>T synonymous_variant 0.18
rpsA 1834015 c.474G>C synonymous_variant 0.16
rpsA 1834021 c.480C>T synonymous_variant 0.33
rpsA 1834030 c.489C>G synonymous_variant 0.33
rpsA 1834033 c.492C>T synonymous_variant 0.14
rpsA 1834073 p.Lys178Arg missense_variant 0.15
rpsA 1834081 c.540C>T synonymous_variant 0.15
rpsA 1834096 c.555G>C synonymous_variant 0.13
rpsA 1834099 c.558C>G synonymous_variant 0.13
rpsA 1834348 c.807T>C synonymous_variant 0.17
rpsA 1834366 c.825A>G synonymous_variant 0.12
rpsA 1834396 c.855G>C synonymous_variant 0.13
rpsA 1834423 c.882G>C synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.19
rpsA 1834465 c.924T>C synonymous_variant 0.21
rpsA 1834468 c.927A>G synonymous_variant 0.29
rpsA 1834489 c.948T>C synonymous_variant 0.24
rpsA 1834513 c.972C>G synonymous_variant 0.19
rpsA 1834520 p.Ala327Ser missense_variant 0.13
rpsA 1834528 c.987T>C synonymous_variant 0.31
rpsA 1834540 c.999G>C synonymous_variant 0.22
rpsA 1834546 c.1005T>C synonymous_variant 0.21
rpsA 1834555 c.1014T>G synonymous_variant 0.17
rpsA 1834609 c.1068T>C synonymous_variant 0.18
rpsA 1834618 c.1077G>C synonymous_variant 0.17
rpsA 1834633 c.1092A>G synonymous_variant 0.22
rpsA 1834639 c.1098T>C synonymous_variant 0.24
rpsA 1834654 p.Glu371Asp missense_variant 0.21
rpsA 1834690 c.1149T>C synonymous_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102014 c.1029C>G synonymous_variant 0.17
ndh 2102020 c.1023A>G synonymous_variant 0.17
ndh 2102023 c.1020G>C synonymous_variant 0.15
ndh 2102026 c.1017G>C synonymous_variant 0.17
katG 2153981 p.Tyr711His missense_variant 0.18
katG 2154724 p.Arg463Leu missense_variant 0.23
katG 2155399 p.Asn238Thr missense_variant 0.22
katG 2155691 c.421T>C synonymous_variant 0.2
katG 2155695 c.417C>G synonymous_variant 0.2
katG 2155704 c.408C>G synonymous_variant 0.17
PPE35 2167780 p.Asn945Tyr missense_variant 0.14
PPE35 2167926 p.Leu896Ser missense_variant 0.42
PPE35 2167965 p.Ala883Gly missense_variant 0.18
PPE35 2167967 c.2646A>C synonymous_variant 0.2
PPE35 2167983 p.Gly877Asp missense_variant 0.57
PPE35 2170066 p.Ala183Thr missense_variant 0.2
Rv1979c 2222308 p.Asp286Gly missense_variant 0.38
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290009 c.-768A>C upstream_gene_variant 0.21
pncA 2290015 c.-774A>C upstream_gene_variant 0.19
pncA 2290024 c.-783C>G upstream_gene_variant 0.23
pncA 2290030 c.-791_-789delAATinsCAC upstream_gene_variant 0.25
pncA 2290033 c.-792C>G upstream_gene_variant 0.25
pncA 2290038 c.-797G>A upstream_gene_variant 0.23
pncA 2290042 c.-801T>C upstream_gene_variant 0.21
pncA 2290069 c.-830_-828delAGCinsGGA upstream_gene_variant 0.15
pncA 2290072 c.-831T>C upstream_gene_variant 0.15
pncA 2290075 c.-834C>G upstream_gene_variant 0.15
pncA 2290084 c.-843T>C upstream_gene_variant 0.15
pncA 2290087 c.-846T>C upstream_gene_variant 0.15
kasA 2518076 c.-39C>T upstream_gene_variant 0.13
kasA 2518132 c.18C>T synonymous_variant 0.5
kasA 2518468 c.354A>C synonymous_variant 0.18
kasA 2518474 c.360G>A synonymous_variant 0.18
kasA 2518483 c.369C>G synonymous_variant 0.22
kasA 2518504 c.390T>C synonymous_variant 0.27
kasA 2518506 p.Ala131Glu missense_variant 0.27
kasA 2518519 c.405G>C synonymous_variant 0.27
kasA 2518528 c.414C>G synonymous_variant 0.18
kasA 2518540 c.426T>C synonymous_variant 0.18
kasA 2518672 c.558G>C synonymous_variant 0.22
kasA 2518678 c.564C>T synonymous_variant 0.2
kasA 2518684 c.570C>G synonymous_variant 0.2
kasA 2518693 c.579C>G synonymous_variant 0.18
kasA 2518696 c.582C>G synonymous_variant 0.18
kasA 2518702 c.588C>T synonymous_variant 0.18
kasA 2518705 c.591T>C synonymous_variant 0.18
kasA 2518711 c.597A>G synonymous_variant 0.17
kasA 2518714 c.600A>C synonymous_variant 0.17
kasA 2518732 c.618C>G synonymous_variant 0.15
kasA 2518747 c.633C>G synonymous_variant 0.14
kasA 2518825 c.711T>C synonymous_variant 0.23
kasA 2518864 c.750G>C synonymous_variant 0.27
kasA 2518879 c.765A>G synonymous_variant 0.36
kasA 2518885 c.771T>C synonymous_variant 0.44
eis 2714743 p.Trp197Leu missense_variant 0.13
ahpC 2726051 c.-142G>A upstream_gene_variant 0.43
ahpC 2726638 p.Ala149Val missense_variant 0.13
ahpC 2726657 c.465A>C synonymous_variant 0.18
ahpC 2726693 c.501C>G synonymous_variant 0.14
ahpC 2726696 c.504C>G synonymous_variant 0.12
Rv2752c 3064632 c.1560C>T synonymous_variant 0.33
Rv2752c 3065013 c.1179G>C synonymous_variant 0.27
Rv2752c 3065018 p.Asn392His missense_variant 0.3
Rv2752c 3065028 p.Val388Ile missense_variant 0.27
Rv2752c 3065040 c.1152C>G synonymous_variant 0.23
Rv2752c 3065048 c.1144C>T synonymous_variant 0.23
Rv2752c 3065052 c.1140G>A synonymous_variant 0.23
Rv2752c 3065055 c.1137T>C synonymous_variant 0.23
Rv2752c 3065064 c.1128G>C synonymous_variant 0.21
Rv2752c 3065073 c.1119C>G synonymous_variant 0.2
Rv2752c 3065079 c.1113T>C synonymous_variant 0.2
Rv2752c 3065082 c.1110G>C synonymous_variant 0.2
Rv2752c 3065087 c.1105A>C synonymous_variant 0.2
Rv2752c 3065088 c.1104A>G synonymous_variant 0.2
thyX 3067325 c.621A>G synonymous_variant 0.14
thyX 3067349 c.597G>C synonymous_variant 0.13
thyX 3067355 c.591A>C synonymous_variant 0.15
thyX 3067367 c.579G>C synonymous_variant 0.15
thyX 3067373 c.573C>G synonymous_variant 0.15
thyX 3067376 c.570G>A synonymous_variant 0.14
thyX 3067652 c.294T>C synonymous_variant 0.19
thyX 3067661 c.285C>G synonymous_variant 0.24
thyX 3067685 c.261A>C synonymous_variant 0.14
thyX 3067691 p.Ile85Met missense_variant 0.14
thyX 3067736 c.210C>T synonymous_variant 0.12
thyX 3067814 c.132T>C synonymous_variant 0.14
thyX 3067850 c.96A>C synonymous_variant 0.21
thyX 3067869 p.Thr26Ser missense_variant 0.18
thyX 3067874 c.72C>G synonymous_variant 0.18
thyX 3067883 c.63C>G synonymous_variant 0.2
thyX 3067886 c.60A>C synonymous_variant 0.22
thyX 3067889 c.57C>G synonymous_variant 0.18
thyX 3067898 p.Asp16Glu missense_variant 0.17
thyA 3073892 c.580T>C synonymous_variant 0.15
thyA 3073929 c.543T>C synonymous_variant 0.18
thyA 3073977 c.495A>G synonymous_variant 0.13
thyA 3073989 c.483T>C synonymous_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 0.43
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.95
fprA 3474306 c.300G>C synonymous_variant 0.22
fprA 3474312 c.306C>T synonymous_variant 0.22
fprA 3474321 c.315C>G synonymous_variant 0.22
fprA 3474324 c.318G>C synonymous_variant 0.22
fprA 3474333 c.327T>C synonymous_variant 0.22
fprA 3474337 p.Met111Ala missense_variant 0.18
fprA 3474340 c.334T>C synonymous_variant 0.17
fprA 3474354 c.348T>C synonymous_variant 0.15
fprA 3474360 p.Asp118Glu missense_variant 0.14
fprA 3474361 c.355C>T synonymous_variant 0.14
fprA 3474372 c.366T>C synonymous_variant 0.13
fprA 3474393 c.387C>G synonymous_variant 0.15
fprA 3474597 c.591C>A synonymous_variant 0.56
fprA 3475159 p.Asn385Asp missense_variant 0.62
fbiB 3640866 c.-669T>C upstream_gene_variant 0.14
fbiA 3640871 p.Ala110Gly missense_variant 0.15
fbiB 3640878 c.-657T>C upstream_gene_variant 0.15
fbiB 3640899 c.-636G>C upstream_gene_variant 0.15
fbiA 3640900 p.Gln120Asn missense_variant 0.15
rpoA 3877482 c.1026C>G synonymous_variant 0.14
rpoA 3877553 p.Glu319Gln missense_variant 0.19
rpoA 3877571 p.Pro313Ala missense_variant 0.18
rpoA 3877818 c.690A>G synonymous_variant 0.17
rpoA 3877848 c.660C>T synonymous_variant 0.14
rpoA 3877905 c.603A>G synonymous_variant 0.13
rpoA 3878055 c.453A>G synonymous_variant 0.14
rpoA 3878061 c.447G>C synonymous_variant 0.15
rpoA 3878082 c.426T>C synonymous_variant 0.15
rpoA 3878102 p.Val136Ile missense_variant 0.16
rpoA 3878103 c.405A>G synonymous_variant 0.26
rpoA 3878118 c.390T>C synonymous_variant 0.22
rpoA 3878143 p.Gly122Asp missense_variant 0.14
rpoA 3878271 c.237T>C synonymous_variant 0.14
clpC1 4038308 p.Val799Ile missense_variant 0.13
clpC1 4038314 c.2391T>C synonymous_variant 0.14
clpC1 4038356 c.2349T>C synonymous_variant 0.15
clpC1 4038499 p.Ser736Arg missense_variant 0.14
clpC1 4038530 p.Glu725Asp missense_variant 0.21
clpC1 4038596 c.2109A>G synonymous_variant 0.14
clpC1 4038953 c.1752A>G synonymous_variant 0.22
clpC1 4038956 c.1749T>C synonymous_variant 0.22
clpC1 4038965 c.1740T>C synonymous_variant 0.2
clpC1 4038971 c.1734T>C synonymous_variant 0.2
clpC1 4038974 c.1731T>C synonymous_variant 0.2
clpC1 4038989 c.1716T>C synonymous_variant 0.18
clpC1 4038997 c.1708T>C synonymous_variant 0.17
clpC1 4039004 c.1701C>G synonymous_variant 0.14
clpC1 4039022 c.1683A>G synonymous_variant 0.13
clpC1 4039121 c.1584T>C synonymous_variant 0.15
clpC1 4039169 p.Glu512Asp missense_variant 0.17
clpC1 4039172 c.1533A>G synonymous_variant 0.17
clpC1 4039178 c.1527G>C synonymous_variant 0.22
clpC1 4039183 c.1522T>C synonymous_variant 0.22
clpC1 4039186 c.1519C>T synonymous_variant 0.25
clpC1 4039226 c.1479T>C synonymous_variant 0.25
clpC1 4039229 c.1476C>G synonymous_variant 0.27
clpC1 4039274 c.1431G>C synonymous_variant 0.23
clpC1 4039654 p.Thr351Ser missense_variant 0.13
clpC1 4039694 c.1011G>C synonymous_variant 0.13
clpC1 4039724 c.981A>G synonymous_variant 0.21
clpC1 4039751 c.954A>G synonymous_variant 0.21
clpC1 4039757 c.948A>G synonymous_variant 0.16
clpC1 4039769 c.936C>G synonymous_variant 0.16
clpC1 4039775 c.930G>C synonymous_variant 0.14
clpC1 4039831 c.874T>C synonymous_variant 0.12
clpC1 4039898 c.807C>G synonymous_variant 0.25
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.3
clpC1 4039931 c.774T>C synonymous_variant 0.3
clpC1 4039937 c.768G>C synonymous_variant 0.18
clpC1 4039946 c.759A>C synonymous_variant 0.22
clpC1 4039952 c.753T>C synonymous_variant 0.27
clpC1 4039979 c.726C>G synonymous_variant 0.25
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.15
clpC1 4040093 c.612C>G synonymous_variant 0.14
clpC1 4040105 c.600C>G synonymous_variant 0.12
clpC1 4040147 c.558A>G synonymous_variant 0.15
clpC1 4040162 c.543G>C synonymous_variant 0.17
clpC1 4040171 c.534C>G synonymous_variant 0.17
clpC1 4040237 c.468C>T synonymous_variant 0.2
clpC1 4040246 c.459C>G synonymous_variant 0.18
clpC1 4040249 c.456A>G synonymous_variant 0.18
clpC1 4040267 c.438A>G synonymous_variant 0.21
clpC1 4040273 c.432T>C synonymous_variant 0.27
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.23
clpC1 4040279 c.426C>G synonymous_variant 0.21
clpC1 4040291 c.414G>C synonymous_variant 0.25
clpC1 4040517 p.Val63Ala missense_variant 0.57
embC 4240183 c.321A>G synonymous_variant 0.14
embC 4240204 c.342T>C synonymous_variant 0.17
embC 4240210 c.348C>G synonymous_variant 0.17
embC 4240216 c.354T>C synonymous_variant 0.15
embC 4240229 p.Leu123Ile missense_variant 0.17
embC 4240232 p.Gln124Val missense_variant 0.15
embC 4240258 c.396T>G synonymous_variant 0.15
embC 4240270 c.408T>C synonymous_variant 0.13
embC 4240277 p.Leu139Val missense_variant 0.13
embC 4240630 c.768C>A synonymous_variant 0.15
embC 4240632 p.Met257Thr missense_variant 0.15
embC 4240642 c.780G>C synonymous_variant 0.15
embC 4240645 c.783G>C synonymous_variant 0.15
embC 4240671 p.Thr270Ile missense_variant 0.87
embC 4240677 p.Gly272Ala missense_variant 0.14
embC 4240685 p.Thr275Ala missense_variant 0.14
embC 4240789 c.927T>C synonymous_variant 0.17
embC 4240831 c.969T>G synonymous_variant 0.14
embC 4241042 p.Asn394Asp missense_variant 0.4
embC 4241047 c.1185C>G synonymous_variant 0.2
embC 4241050 c.1188T>G synonymous_variant 0.2
embC 4241053 c.1191G>C synonymous_variant 0.2
embC 4241089 c.1227C>G synonymous_variant 0.2
embC 4241095 c.1233C>T synonymous_variant 0.2
embC 4241107 c.1245G>C synonymous_variant 0.14
embC 4241140 c.1278A>G synonymous_variant 0.17
embC 4241173 c.1311C>T synonymous_variant 0.13
embC 4241203 c.1341T>C synonymous_variant 0.17
embC 4241206 c.1344G>C synonymous_variant 0.17
embC 4241218 c.1356G>C synonymous_variant 0.13
embC 4241230 c.1368A>G synonymous_variant 0.14
embC 4241233 c.1371G>C synonymous_variant 0.14
embC 4241449 c.1587C>G synonymous_variant 0.15
embC 4241453 p.Ile531Val missense_variant 0.13
embC 4241479 c.1617C>G synonymous_variant 0.15
embC 4241480 c.1618T>C synonymous_variant 0.15
embC 4241488 c.1626G>C synonymous_variant 0.25
embC 4241496 p.Ala545Gly missense_variant 0.27
embC 4241500 c.1638A>C synonymous_variant 0.27
embC 4241501 p.Ser547Thr missense_variant 0.27
embC 4241506 c.1644G>C synonymous_variant 0.27
embC 4241518 c.1656A>G synonymous_variant 0.18
embC 4241521 c.1659T>C synonymous_variant 0.18
embC 4241551 c.1689A>G synonymous_variant 0.14
embC 4241567 p.Ile569Val missense_variant 0.17
embC 4241572 c.1710C>G synonymous_variant 0.17
embC 4241611 c.1749G>C synonymous_variant 0.14
embC 4241614 c.1752A>C synonymous_variant 0.15
embC 4241626 c.1764T>C synonymous_variant 0.25
embC 4241635 c.1773G>C synonymous_variant 0.22
embC 4241644 c.1782G>C synonymous_variant 0.29
embC 4241648 c.1786T>C synonymous_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.35
embA 4243848 p.Val206Met missense_variant 0.44
embA 4245083 c.1851A>C synonymous_variant 0.14
embA 4245092 c.1860C>G synonymous_variant 0.13
embA 4245101 c.1869G>C synonymous_variant 0.15
embA 4245137 c.1905T>C synonymous_variant 0.22
embA 4245146 c.1914G>A synonymous_variant 0.24
embA 4245149 c.1917C>G synonymous_variant 0.21
embA 4245153 p.Ile641Val missense_variant 0.21
embA 4245182 c.1950T>C synonymous_variant 0.2
embA 4245189 c.1957C>T synonymous_variant 0.19
embA 4245198 p.Leu656Ile missense_variant 0.2
embA 4245207 c.1975T>C synonymous_variant 0.2
embA 4245215 c.1983A>C synonymous_variant 0.18
embA 4245969 p.Pro913Ser missense_variant 0.82
embB 4247356 c.843C>T synonymous_variant 0.57
embB 4247646 p.Glu378Ala missense_variant 0.6
embB 4248085 c.1572T>C synonymous_variant 0.13
embB 4248130 c.1617G>C synonymous_variant 0.14
embB 4248133 c.1620C>G synonymous_variant 0.14
embB 4248157 c.1644A>G synonymous_variant 0.17
embB 4249498 c.2985G>C synonymous_variant 0.2
embB 4249521 p.Ala1003Val missense_variant 0.17
embB 4249525 c.3012T>C synonymous_variant 0.17
embB 4249529 p.Ile1006Val missense_variant 0.17
embB 4249532 p.Ala1007Thr missense_variant 0.17
embB 4249537 c.3024A>G synonymous_variant 0.2
embB 4249543 c.3030G>C synonymous_variant 0.2
embB 4249546 c.3033G>A synonymous_variant 0.2
aftB 4268102 c.735C>G synonymous_variant 0.12
aftB 4268125 p.Ser238Gly missense_variant 0.14
aftB 4268129 c.708T>G synonymous_variant 0.14
aftB 4268138 c.699A>C synonymous_variant 0.18
aftB 4268169 p.Ala223Gly missense_variant 0.15
aftB 4268171 c.666G>C synonymous_variant 0.15
aftB 4268179 c.658T>C synonymous_variant 0.14
aftB 4268182 p.Phe219Leu missense_variant 0.14
aftB 4268183 c.654A>T synonymous_variant 0.14
aftB 4268193 p.Leu215Ala missense_variant 0.14
aftB 4268683 p.Gly52Ser missense_variant 0.5
aftB 4268994 c.-158T>G upstream_gene_variant 0.14
aftB 4268999 c.-163C>T upstream_gene_variant 0.14
aftB 4269006 c.-170T>C upstream_gene_variant 0.18
aftB 4269012 c.-176G>C upstream_gene_variant 0.2
aftB 4269027 c.-191C>T upstream_gene_variant 0.18
aftB 4269033 c.-197T>C upstream_gene_variant 0.17
aftB 4269036 c.-200C>G upstream_gene_variant 0.17
aftB 4269042 c.-206G>C upstream_gene_variant 0.15
ubiA 4269075 p.Ile253Val missense_variant 0.14
aftB 4269081 c.-245G>C upstream_gene_variant 0.14
ubiA 4269387 p.Glu149Asp missense_variant 0.47
aftB 4269606 c.-770T>C upstream_gene_variant 0.56
whiB6 4338441 p.Tyr27* stop_gained 0.62
whiB6 4338449 p.Ala25Pro missense_variant 0.67
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 0.68
gid 4407588 c.615A>G synonymous_variant 0.68
gid 4407873 c.330G>T synonymous_variant 0.38