TB-Profiler result

Run: ERR4820911
Summary

Run ID: ERR4820911

Sample name:

Date: 01-04-2023 16:57:13

Number of reads: 973867

Percentage reads mapped: 98.78

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575924 p.Gly193Arg missense_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761007 p.Gln401Lys missense_variant 0.17
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 766925 p.Phe1186Leu missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777878 p.Asp201Glu missense_variant 0.18
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781426 c.-134C>G upstream_gene_variant 1.0
fbiC 1303165 p.Ser79Arg missense_variant 0.22
fbiC 1304199 c.1269C>A synonymous_variant 0.15
fbiC 1304876 p.Ile649Ser missense_variant 0.25
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472448 n.603T>G non_coding_transcript_exon_variant 0.2
inhA 1673816 c.-386G>A upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
folC 2746448 p.Asp384Val missense_variant 0.18
thyX 3067987 c.-42C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448962 c.459C>T synonymous_variant 0.17
Rv3083 3449177 p.Lys225Thr missense_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474211 p.Lys69Gln missense_variant 0.3
fprA 3475245 c.1239C>T synonymous_variant 0.18
Rv3236c 3612876 p.Glu81Lys missense_variant 0.12
Rv3236c 3613255 c.-139G>T upstream_gene_variant 0.13
fbiB 3642471 p.Met313Val missense_variant 0.1
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244545 p.Ala438Asp missense_variant 0.17
embB 4246707 p.Gly65Asp missense_variant 1.0
whiB6 4338239 p.Leu95Met missense_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408261 c.-59G>T upstream_gene_variant 0.12