TB-Profiler result

Run: ERR4822046
Summary

Run ID: ERR4822046

Sample name:

Date: 01-04-2023 17:36:19

Number of reads: 1288533

Percentage reads mapped: 99.66

Strain: lineage4.6

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8266 p.Ala322Glu missense_variant 0.98
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491349 c.567T>C synonymous_variant 1.0
fgd1 491535 c.753G>A synonymous_variant 0.1
rpoC 766586 p.Glu1073Lys missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775822 p.Val887Met missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303098 c.168C>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 0.12
rrs 1473318 n.1473G>A non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156267 c.-156A>C upstream_gene_variant 1.0
PPE35 2167928 c.2685G>T synonymous_variant 0.1
PPE35 2170048 p.Leu189Val missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878658 c.-151A>C upstream_gene_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328462 c.-989C>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407554 p.Arg217Trp missense_variant 1.0