TB-Profiler result

Run: ERR551135
Summary

Run ID: ERR551135

Sample name:

Date: 15-08-2022 10:52:13

Number of reads: 440966

Percentage reads mapped: 99.46

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 620389 c.499C>T synonymous_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 766073 p.Ala902Thr missense_variant 0.11
rpoC 766409 c.3043_3046delTTCC frameshift_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777835 p.Ile216Val missense_variant 0.12
mmpS5 778854 p.Val18Leu missense_variant 1.0
mmpS5 779685 c.-780T>C upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473094 n.1249T>C non_coding_transcript_exon_variant 1.0
rrs 1473277 n.1432G>T non_coding_transcript_exon_variant 0.11
rrl 1475104 n.1450dupG non_coding_transcript_exon_variant 0.15
inhA 1674520 p.Pro107Ser missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156056 p.Gly19Val missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167946 c.2667C>T synonymous_variant 1.0
PPE35 2168460 p.Asn718Ser missense_variant 1.0
Rv1979c 2223077 p.Ala30Ser missense_variant 0.15
Rv1979c 2223128 p.Lys13Glu missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2715001 p.Ser111Phe missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086954 c.135C>A synonymous_variant 0.17
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3474123 c.117G>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
Rv3236c 3612933 p.Ala62Thr missense_variant 0.12
Rv3236c 3613160 c.-44C>T upstream_gene_variant 0.13
ddn 3987111 p.Leu90Val missense_variant 1.0
embC 4242476 p.Pro872Ala missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242881 p.Pro1007Thr missense_variant 0.2
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269130 p.Leu235Pro missense_variant 0.12
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326990 p.Ile162Val missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
Rv1979c 2220946 c.277_*772del stop_lost&conservative_inframe_deletion&splice_region_variant 1.0