TB-Profiler result

Run: ERR7764340
Summary

Run ID: ERR7764340

Sample name:

Date: 02-04-2023 05:43:53

Number of reads: 2647321

Percentage reads mapped: 99.75

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.23
mshA 576113 p.Arg256Gly missense_variant 0.27
mshA 576616 c.1269G>C synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168370 p.Ala748Glu missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.1
PPE35 2170053 p.Thr187Ser missense_variant 0.11
PPE35 2170065 p.Ala183Gly missense_variant 0.27
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.64
fbiD 3339746 p.Ala210Gly missense_variant 0.36
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.2
embB 4246584 p.Arg24Pro missense_variant 0.21
embB 4248324 p.Ala604Gly missense_variant 0.37
embB 4248328 c.1815G>C synonymous_variant 0.18
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0