TB-Profiler result

Run: SRR13837421
Summary

Run ID: SRR13837421

Sample name:

Date: 03-04-2023 09:09:53

Number of reads: 887035

Percentage reads mapped: 98.63

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embB 4247891 p.Arg460Cys missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6088 c.849C>A synonymous_variant 1.0
rpoB 761786 c.1980C>T synonymous_variant 1.0
rpoC 764973 p.Asp535Ala missense_variant 1.0
rpsL 781532 c.-28G>T upstream_gene_variant 1.0
rpsL 781728 c.169T>C synonymous_variant 0.12
fbiC 1302843 c.-88A>C upstream_gene_variant 1.0
fbiC 1302887 c.-43delG upstream_gene_variant 1.0
rrl 1473434 n.-224T>C upstream_gene_variant 1.0
rrl 1476368 n.2711T>A non_coding_transcript_exon_variant 0.95
katG 2156364 c.-253T>G upstream_gene_variant 1.0
Rv1979c 2221814 p.Leu451Val missense_variant 1.0
Rv1979c 2222030 p.Val379Met missense_variant 1.0
kasA 2519238 p.Thr375Lys missense_variant 1.0
folC 2747285 p.Val105Ala missense_variant 1.0
pepQ 2859712 p.Thr236Ser missense_variant 1.0
Rv2752c 3065064 c.1128G>T synonymous_variant 1.0
thyX 3068085 c.-140T>A upstream_gene_variant 1.0
ald 3087003 p.Asp62His missense_variant 1.0
Rv3083 3448914 p.Ile137Met missense_variant 1.0
fprA 3475146 c.1141delA frameshift_variant 1.0
whiB7 3568676 p.Ser2Pro missense_variant 1.0
fbiA 3641491 p.Ala317Pro missense_variant 1.0
alr 3840235 p.Gly396* stop_gained 1.0
alr 3840304 c.1116delT frameshift_variant 1.0
alr 3841263 p.Arg53His missense_variant 1.0
embC 4241029 p.Trp389* stop_gained 1.0
embB 4249631 p.Thr1040Pro missense_variant 1.0
ethA 4327197 p.Gly93Arg missense_variant 1.0