TB-Profiler result

Run: SRR13861614
Summary

Run ID: SRR13861614

Sample name:

Date: 03-04-2023 09:36:23

Number of reads: 2393470

Percentage reads mapped: 47.92

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5709 p.Gly157Val missense_variant 1.0
gyrA 9028 p.Val576Ala missense_variant 1.0
rpoB 762011 c.2205G>C synonymous_variant 1.0
rpoB 762279 c.2474delA frameshift_variant 1.0
mmpS5 778823 p.Ile28Thr missense_variant 1.0
fbiC 1304640 c.1710A>C synonymous_variant 1.0
Rv1258c 1406376 p.Gly322Val missense_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.31
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.36
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.36
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.36
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.37
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.41
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.44
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.43
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.43
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.43
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.43
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.42
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.42
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.42
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.42
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.41
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.37
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.37
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.35
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.34
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.14
PPE35 2169882 p.Ser244Ile missense_variant 0.99
eis 2714940 c.392delA frameshift_variant 1.0
ald 3087311 c.492C>G synonymous_variant 1.0
fbiB 3642465 p.Asp311His missense_variant 1.0
alr 3840300 p.Pro374His missense_variant 1.0
rpoA 3878288 p.Thr74Pro missense_variant 1.0
clpC1 4039415 c.1289dupA frameshift_variant 1.0
clpC1 4040792 c.-88A>T upstream_gene_variant 1.0
embA 4243235 c.3G>T synonymous_variant 1.0