TB-Profiler result

Run: SRR15316114

Summary

Run ID: SRR15316114

Sample name:

Date: 03-04-2023 13:10:55

Number of reads: 9164074

Percentage reads mapped: 95.89

Strain: lineage4.4.2;lineage2.2.1.1

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.09
lineage4 Euro-American LAM;T;S;X;H None 0.92
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.08
lineage4.4 Euro-American S;T None 0.91
lineage4.4.2 Euro-American T1;T2 None 0.92
lineage2.2.1.1 East-Asian (Beijing) Beijing-RD150 RD105;RD207;RD181;RD150 0.09
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491377 p.Gly199Arg missense_variant 0.89
ccsA 620625 p.Ile245Met missense_variant 0.12
rpoB 762745 p.Gln980Pro missense_variant 0.93
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066099 p.Met31Ile missense_variant 0.92
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 0.11
ddn 3987175 p.Ala111Val missense_variant 0.93
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 0.1
embB 4246508 c.-6G>A upstream_gene_variant 0.89
aftB 4268928 c.-92C>T upstream_gene_variant 0.92
aftB 4269375 c.-539G>A upstream_gene_variant 0.91
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.13