TB-Profiler result

Run: SRR23650986
Summary

Run ID: SRR23650986

Sample name:

Date: 2024-04-16T01:45:03.720238

Number of reads: 11506452

Percentage reads mapped: 99.93

Median coverage: 251.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rpoA 3878614 c.-107A>C upstream_gene_variant 0.14 rifampicin
rpoA 3878619 c.-112A>C upstream_gene_variant 0.18 rifampicin
embB 4247028 p.Leu172Arg missense_variant 0.28 ethambutol
embB 4247033 p.Ser174Arg missense_variant 0.21 ethambutol
embB 4247039 p.Phe176Val missense_variant 0.16 ethambutol