TB-Profiler result

Run: SRR3647357

Summary

Run ID: SRR3647357

Sample name:

Date: 04-04-2023 05:21:24

Number of reads: 6769034

Percentage reads mapped: 99.05

Strain:

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5671 c.432C>T synonymous_variant 0.99
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 0.98
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.99
mshA 575572 c.225T>C synonymous_variant 0.99
rpoB 759837 c.33_44dupTAGTCCTAGTCC disruptive_inframe_insertion 0.44
rpoB 759851 c.45G>T synonymous_variant 0.17
rpoC 763031 c.-339T>C upstream_gene_variant 0.99
rpoC 766108 p.Asp913Glu missense_variant 0.98
mmpL5 775639 p.Ile948Val missense_variant 0.99
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473079 n.1234G>A non_coding_transcript_exon_variant 0.99
tlyA 1917972 c.33A>G synonymous_variant 0.98
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 0.99
katG 2156056 p.Gly19Val missense_variant 0.98
PPE35 2167926 p.Leu896Ser missense_variant 0.99
PPE35 2168460 p.Asn718Ser missense_variant 0.99
Rv1979c 2222308 p.Asp286Gly missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2715185 p.Asp50Tyr missense_variant 0.99
folC 2746572 p.Arg343Cys missense_variant 0.99
ald 3086728 c.-92C>T upstream_gene_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474123 c.117G>A synonymous_variant 0.99
fprA 3475159 p.Asn385Asp missense_variant 0.98
Rv3236c 3611966 p.Ser384Leu missense_variant 0.99
rpoA 3878512 c.-6_-5insGAA upstream_gene_variant 0.98
ddn 3987111 p.Leu90Val missense_variant 0.98
embC 4240671 p.Thr270Ile missense_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246864 c.351C>T synonymous_variant 0.97
embB 4247646 p.Glu378Ala missense_variant 0.99
aftB 4269351 c.-515C>T upstream_gene_variant 0.98
ubiA 4269387 p.Glu149Asp missense_variant 0.98
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326567 p.Arg303Gly missense_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 0.99
gid 4407588 c.615A>G synonymous_variant 0.99