TB-Profiler result

Run: SRR5485526
Summary

Run ID: SRR5485526

Sample name:

Date: 18-08-2022 08:32:51

Number of reads: 88835

Percentage reads mapped: 96.72

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.92 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.33 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpsL 781749 p.Thr64Ala missense_variant 0.19
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.48
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.17
rrs 1472711 n.866A>G non_coding_transcript_exon_variant 0.15
rrs 1472721 n.876C>A non_coding_transcript_exon_variant 0.17
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.92
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.92
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.92
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.92
rrs 1473287 n.1442C>T non_coding_transcript_exon_variant 0.17
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.92
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.92
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.33
pncA 2289264 c.-23T>A upstream_gene_variant 0.2