TB-Profiler result

Run: ERR11068519
Summary

Run ID: ERR11068519

Sample name:

Date: 06-04-2023 15:53:39

Number of reads: 4127067

Percentage reads mapped: 99.28

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9422 c.2121C>T synonymous_variant 1.0
gyrA 9596 c.2295G>T synonymous_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576119 p.Ala258Pro missense_variant 0.33
ccsA 619977 c.87G>A synonymous_variant 0.17
ccsA 620130 c.240G>A synonymous_variant 0.18
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762706 p.Ser967Leu missense_variant 0.11
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 764181 p.Asp271Gly missense_variant 1.0
rpoC 766503 p.Pro1045Leu missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303918 p.Arg330Ser missense_variant 0.12
fbiC 1303940 p.Leu337Pro missense_variant 0.15
Rv1258c 1407075 p.Val89Ala missense_variant 0.17
Rv1258c 1407109 p.Ala78Thr missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917966 c.27C>T synonymous_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101759 c.1284G>A synonymous_variant 0.11
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170769 c.-157C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
folC 2747723 c.-125G>A upstream_gene_variant 0.17
thyX 3067277 c.669C>T synonymous_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568434 c.246G>T synonymous_variant 0.15
fbiB 3641966 c.432C>T synonymous_variant 0.2
clpC1 4038182 c.2523C>T synonymous_variant 0.29
clpC1 4040246 c.459C>T synonymous_variant 0.14
embC 4241659 c.1797G>C synonymous_variant 0.15
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ubiA 4269727 p.Pro36Leu missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0