TB-Profiler result

Run: ERR1750885
Summary

Run ID: ERR1750885

Sample name:

Date: 31-03-2023 14:58:34

Number of reads: 8617952

Percentage reads mapped: 95.66

Strain: lineage2.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.99
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.98
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.98
gyrA 9304 p.Gly668Asp missense_variant 0.99
fgd1 491742 c.960T>C synonymous_variant 0.98
mshA 575907 p.Ala187Val missense_variant 0.97
ccsA 620625 p.Ile245Met missense_variant 0.99
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.98
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 0.99
Rv1258c 1407143 c.198C>T synonymous_variant 0.98
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.15
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.27
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.15
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.43
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.11
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.11
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.11
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.35
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.13
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.13
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.18
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.18
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.2
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.11
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.1
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.15
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.14
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.13
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.14
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.15
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.17
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.14
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.16
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.16
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.18
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.11
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.1
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.18
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.13
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.16
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.11
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.12
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.13
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.12
rrl 1475059 n.1404_1405delCA non_coding_transcript_exon_variant 0.15
rrl 1475064 n.1407G>A non_coding_transcript_exon_variant 0.14
rrl 1475067 n.1410_1411insG non_coding_transcript_exon_variant 0.14
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.13
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.13
rrl 1475081 n.1424C>G non_coding_transcript_exon_variant 0.13
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.12
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.22
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.22
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.13
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.31
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.27
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.14
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.21
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.11
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.11
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.21
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.21
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.18
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.13
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.14
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.17
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.15
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.15
rpsA 1834177 c.636A>C synonymous_variant 0.99
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.98
PPE35 2167926 p.Leu896Ser missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 0.99
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
Rv3236c 3612813 p.Thr102Ala missense_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 0.99
embB 4246567 c.54G>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.99
gid 4407927 p.Glu92Asp missense_variant 0.98