TB-Profiler result

Run: ERR2513507
Summary

Run ID: ERR2513507

Sample name:

Date: 31-03-2023 19:44:04

Number of reads: 6257507

Percentage reads mapped: 99.19

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1.2.2 Indo-Oceanic EAI1 RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5075 c.-165C>T upstream_gene_variant 1.0
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrA 7268 c.-34C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490828 p.Ala16Thr missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575771 p.Val142Ile missense_variant 0.14
mshA 576205 c.858G>A synonymous_variant 0.29
mshA 576667 p.Ser440Arg missense_variant 0.5
mshA 576715 c.1368C>T synonymous_variant 0.33
ccsA 619835 c.-56G>A upstream_gene_variant 0.2
ccsA 620185 p.Gly99Ser missense_variant 0.25
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776821 p.Val554Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304095 p.Val389Met missense_variant 0.2
embR 1417019 p.Cys110Tyr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168742 p.Gly624Asp missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518774 c.660C>T synonymous_variant 0.12
eis 2715072 c.261G>A synonymous_variant 0.22
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
folC 2746362 p.Asp413Asn missense_variant 0.12
folC 2746647 p.Gln318* stop_gained 0.15
folC 2747331 p.His90Asn missense_variant 0.14
pepQ 2859633 c.786G>A synonymous_variant 0.14
Rv2752c 3064750 p.Arg481Leu missense_variant 1.0
thyX 3067433 c.513C>T synonymous_variant 0.5
thyX 3067945 p.Val1Met missense_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339580 p.Gly155Ser missense_variant 0.17
Rv3083 3448714 p.Asp71His missense_variant 1.0
Rv3083 3449331 c.828C>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240577 p.Ala239Thr missense_variant 0.2
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embC 4241089 c.1227C>T synonymous_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244480 c.1248G>A synonymous_variant 0.22
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4246722 p.Pro70Gln missense_variant 0.18
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4247671 c.1158G>A synonymous_variant 0.29
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326148 c.1326G>T synonymous_variant 1.0
ethA 4326439 p.Asn345Lys missense_variant 1.0
whiB6 4338203 p.Arg107Cys missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0