TB-Profiler result

Run: ERR2513708
Summary

Run ID: ERR2513708

Sample name:

Date: 31-03-2023 19:51:18

Number of reads: 909049

Percentage reads mapped: 99.61

Strain: lineage2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.1 East-Asian (non-Beijing) None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576318 p.Arg324Gln missense_variant 1.0
mshA 576738 p.Val464Gly missense_variant 0.25
mshA 576751 p.Lys468Asn missense_variant 0.2
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 765121 c.1752G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303038 c.108T>A synonymous_variant 0.13
fbiC 1304443 p.Ala505Thr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918068 c.129C>A synonymous_variant 0.17
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2154938 p.Arg392Trp missense_variant 0.12
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167998 p.Pro872Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726341 p.Val50Gly missense_variant 0.22
folC 2746475 p.Leu375Pro missense_variant 0.12
Rv2752c 3065616 c.576C>T synonymous_variant 1.0
thyA 3074654 c.-183T>G upstream_gene_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449234 p.Arg244His missense_variant 0.11
Rv3083 3449270 p.Gln256Arg missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4040841 c.-138delG upstream_gene_variant 1.0
embC 4240605 p.Leu248Arg missense_variant 0.12
embC 4240655 p.Ala265Pro missense_variant 0.2
embC 4241955 p.Ala698Val missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245834 c.2603_2609delTGGTGGT frameshift_variant 0.11
embA 4245844 p.Val871Glu missense_variant 0.11
embA 4245846 p.Ser872Thr missense_variant 0.11
embA 4245848 c.2616_2617insACCACCA frameshift_variant 0.11
embB 4246088 c.-426A>G upstream_gene_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
ubiA 4269232 p.Arg201His missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0