Run ID: ERR3335729
Sample name:
Date: 01-04-2023 01:52:17
Number of reads: 7380778
Percentage reads mapped: 99.4
Strain: lineage3
Drug-resistance: MDR-TB
| Drug | Resistance | Supporting mutations |
|---|
| Lineage | Family | Main Spoligotype | RDs | Frequency |
|---|---|---|---|---|
| lineage3 | East-African-Indian | CAS | RD750 | 1.0 |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
|---|---|---|---|---|---|
| rpoB | 761095 | p.Leu430Pro | missense_variant | 1.0 | rifampicin |
| rpoB | 761110 | p.Asp435Gly | missense_variant | 1.0 | rifampicin |
| katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
| embB | 4247431 | p.Met306Ile | missense_variant | 1.0 | ethambutol |
| Gene | Chromosome position | Mutation | Type | Estimated fraction |
|---|---|---|---|---|
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 |
| rpoB | 759746 | c.-61C>T | upstream_gene_variant | 1.0 |
| rpoC | 762434 | c.-936T>G | upstream_gene_variant | 0.99 |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 0.99 |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 |
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
| embR | 1416960 | p.Arg130Trp | missense_variant | 1.0 |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
| tlyA | 1918223 | p.Gly95Glu | missense_variant | 0.99 |
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 |
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 0.99 |
| pncA | 2289047 | c.195C>T | synonymous_variant | 0.99 |
| pncA | 2289365 | c.-125delC | upstream_gene_variant | 1.0 |
| eis | 2715012 | c.321C>T | synonymous_variant | 1.0 |
| ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 |
| ribD | 2987187 | c.349C>T | synonymous_variant | 0.99 |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
| ald | 3087390 | p.Gly191Ser | missense_variant | 0.99 |
| fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
| Rv3236c | 3612673 | c.444G>T | synonymous_variant | 0.99 |
| embC | 4242075 | p.Arg738Gln | missense_variant | 1.0 |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
| embB | 4246571 | p.Phe20Leu | missense_variant | 0.99 |
| whiB6 | 4338182 | p.Gln114Glu | missense_variant | 1.0 |
| whiB6 | 4338592 | c.-71G>A | upstream_gene_variant | 1.0 |
| whiB6 | 4338595 | c.-75_-74insA | upstream_gene_variant | 1.0 |
| whiB6 | 4338598 | c.-78delA | upstream_gene_variant | 1.0 |
| gid | 4407588 | c.615A>G | synonymous_variant | 1.0 |
