TB-Profiler result

Run: ERR4178291
Summary

Run ID: ERR4178291

Sample name:

Date: 01-04-2023 04:38:03

Number of reads: 734769

Percentage reads mapped: 43.79

Strain: lineage4.3.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764857 c.1488G>C synonymous_variant 0.19
rpoC 764858 p.Leu497Met missense_variant 0.19
rpoC 764869 c.1500C>T synonymous_variant 0.16
rpoC 764872 c.1503A>G synonymous_variant 0.16
rpoC 764875 c.1506C>G synonymous_variant 0.16
rpoC 764878 c.1509C>G synonymous_variant 0.16
rpoC 764887 c.1518G>T synonymous_variant 0.15
rpoC 764888 c.1519T>C synonymous_variant 0.16
rpoC 764893 c.1524T>C synonymous_variant 0.16
rpoC 764902 c.1533C>G synonymous_variant 0.19
rpoC 764911 c.1542A>G synonymous_variant 0.21
rpoC 764912 p.Met515Val missense_variant 0.21
rpoC 764918 p.Val517Ile missense_variant 0.22
rpoC 764935 c.1566T>C synonymous_variant 0.24
rpoC 764948 c.1579T>C synonymous_variant 0.22
rpoC 764953 c.1584G>T synonymous_variant 0.21
rpoC 764956 c.1587T>C synonymous_variant 0.22
rpoC 764958 p.Glu530Ala missense_variant 0.23
rpoC 764968 c.1599T>C synonymous_variant 0.22
rpoC 764995 c.1626C>G synonymous_variant 0.8
rpoC 764998 c.1629G>T synonymous_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801151 p.Thr115Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.33
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.4
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.44
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.44
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.44
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.44
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.53
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.5
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.48
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.48
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.53
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 0.53
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.45
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.45
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.45
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.45
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.43
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.43
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 0.45
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.45
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.45
rrl 1476483 n.2826G>A non_coding_transcript_exon_variant 0.37
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.25
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878619 c.-112A>C upstream_gene_variant 0.29
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4326207 p.Gly423Arg missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0