Run ID: ERR4553791
Sample name:
Date: 01-04-2023 06:20:50
Number of reads: 1499629
Percentage reads mapped: 99.8
Strain: lineage4.9
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | T1 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761139 | p.His445Asn | missense_variant | 1.0 | rifampicin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
pncA | 2288727 | p.Leu172Pro | missense_variant | 0.61 | pyrazinamide |
pncA | 2288962 | p.Phe94Leu | missense_variant | 0.17 | pyrazinamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrB | 6166 | c.927C>T | synonymous_variant | 1.0 |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
mshA | 576108 | p.Ala254Gly | missense_variant | 0.32 |
rpoB | 761277 | p.Ile491Leu | missense_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2170065 | p.Ala183Gly | missense_variant | 0.21 |
pncA | 2288754 | p.Val163Gly | missense_variant | 0.25 |
fbiD | 3339734 | p.Ala206Gly | missense_variant | 0.41 |
embB | 4246584 | p.Arg24Pro | missense_variant | 0.12 |
aftB | 4269171 | c.-335C>T | upstream_gene_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4408063 | p.Arg47Gln | missense_variant | 1.0 |