Run ID: SRR18910194
Sample name:
Date: 2024-10-04T00:38:06.517506
Number of reads: 1139296
Percentage reads mapped: 56.63
Median coverage: 46.0
Strain: lineage2.2.2
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 0.94 |
lineage2.2.2 | East-Asian (Beijing) | RD105;RD207 | 0.78 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.96 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | inhA | c.-154G>A | Assoc w R | Alias fabG1_p.Leu203Leu. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) |
ethambutol | embB | p.His312Arg | Mutation from literature | |
pyrazinamide | panD | p.Val138Ala | Mutation from literature | |
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | inhA | c.-154G>A | Assoc w R - Interim | Alias fabG1_p.Leu203Leu |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance | Mutation from literature |
inhA | 1674048 | c.-154G>A | upstream_gene_variant | 0.68 | ethionamide | Assoc w R - Interim | Alias fabG1_p.Leu203Leu |
isoniazid | Assoc w R | Alias fabG1_p.Leu203Leu. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | |||||
panD | 4043869 | p.Val138Ala | missense_variant | 0.2 | pyrazinamide | Mutation from literature | |
embB | 4247448 | p.His312Arg | missense_variant | 0.22 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 534 | c.534T>C | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
dnaA | 537 | c.537C>A | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
dnaA | 558 | c.558G>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 561 | c.561C>T | synonymous_variant | 0.3 | isoniazid | |
dnaA | 567 | c.567C>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 582 | c.582A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 585 | c.585A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 588 | c.588A>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 600 | c.600T>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 0.34 | isoniazid | |
dnaA | 645 | c.645A>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 654 | c.654A>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 657 | c.657C>T | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
dnaA | 660 | c.660G>C | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 669 | c.669C>T | synonymous_variant | 0.27 | isoniazid | |
dnaA | 672 | c.672T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 682 | c.682_684delTTGinsCTC | synonymous_variant | 0.28 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 771 | c.771A>T | synonymous_variant | 0.36 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.36 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805_807delTTGinsCTC | synonymous_variant | 0.36 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.36 | isoniazid | |
dnaA | 819 | c.819C>T | synonymous_variant | 0.34 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.3 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 882 | c.882C>T | synonymous_variant | 0.32 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.36 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 0.39 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.38 | isoniazid | |
dnaA | 954 | c.954G>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.44 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.48 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>G | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 999 | c.999C>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.44 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1032 | c.1032G>A | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1059 | c.1059C>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1116 | c.1116C>G | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1119 | c.1119G>A | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.44 | isoniazid | Not assoc w R - Interim |
dnaA | 1170 | c.1170C>T | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1179 | c.1179G>T | synonymous_variant | 0.46 | isoniazid | Not assoc w R - Interim |
dnaA | 1185 | c.1185C>G | synonymous_variant | 0.45 | isoniazid | Not assoc w R - Interim |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.43 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.36 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1257 | c.1257C>T | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.34 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1311 | c.1311C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1347 | c.1347C>T | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1356 | c.1356T>C | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.2 | isoniazid | |
gyrB | 6130 | c.891T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6169 | c.930C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6172 | c.933C>T | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6178 | c.939C>T | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6193 | c.954G>A | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6196 | c.957C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>A | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6229 | c.990G>A | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6247 | c.1008G>A | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6262 | c.1023G>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6334 | c.-968G>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6559 | c.-743C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6565 | c.-737G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6571 | c.-731T>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6580 | c.-722C>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6589 | c.-713G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6592 | c.-710C>T | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6715 | c.1476C>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6850 | c.1611C>A | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6866 | c.-436C>T | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6869 | c.-433T>C | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6931 | c.-371A>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6941 | c.-361C>T | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6950 | c.-352_-350delCTCinsTTG | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6997 | c.-305G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8235 | c.934_936delTTAinsCTG | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8315 | c.1014G>A | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.43 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8360 | c.1059G>A | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8367 | c.1066C>T | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8390 | c.1089C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364Leu | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8429 | c.1128C>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8456 | c.1155C>T | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8730 | p.Gly477Arg | missense_variant | 0.53 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.53 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.55 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8882 | c.1581G>A | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8972 | c.1671C>T | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8978 | c.1677C>T | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.36 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9038 | c.1737C>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9077 | c.1776C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9092 | c.1791C>T | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9128 | c.1827C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9152 | c.1851C>T | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9261 | c.1960_1962delCGCinsAGA | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9266 | c.1965C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044_2046delAGGinsCGC | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9356 | c.2055G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13897 | c.-339C>T | upstream_gene_variant | 0.19 | isoniazid | |
fgd1 | 491031 | c.249C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491085 | c.303T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491088 | c.306C>T | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491112 | c.330G>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491137 | p.Glu119Gln | missense_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491172 | c.390C>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491223 | c.441C>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491226 | c.444C>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491229 | c.447C>T | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491277 | c.495G>A | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491289 | c.507C>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491355 | c.573C>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575803 | c.456C>T | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575806 | c.459G>C | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.36 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.34 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
mshA | 575872 | c.525C>T | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619668 | c.-223C>G | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619672 | c.-219A>T | upstream_gene_variant | 0.31 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619697 | c.-194_-192delAGGinsCGC | upstream_gene_variant | 0.32 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620226 | c.336G>A | synonymous_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620256 | c.366C>G | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620301 | c.411G>T | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620397 | c.507C>G | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620404 | c.514C>T | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620409 | c.519C>G | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.25 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.24 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>A | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620442 | c.552G>T | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620598 | c.708C>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620604 | c.714C>G | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620607 | c.717T>C | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620613 | c.723C>A | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620625 | c.735A>T | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620659 | c.769_771delCGCinsAGG | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620664 | c.774C>T | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620710 | p.Val274Ile | missense_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>G | synonymous_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620763 | c.873G>A | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620766 | c.876C>G | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620787 | c.897C>A | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620790 | c.900C>T | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620808 | c.918T>C | synonymous_variant | 0.33 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620823 | c.933C>T | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620832 | c.942C>T | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 0.98 | ethionamide | Uncertain significance |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657650 | c.-180G>A | upstream_gene_variant | 0.23 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.3 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.31 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.35 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.38 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.41 | ethionamide | |
hadA | 731682 | c.-248C>G | upstream_gene_variant | 0.48 | isoniazid | |
hadA | 731687 | c.-243_-242insCACAGATCTTTT | upstream_gene_variant | 0.44 | isoniazid | |
hadA | 731693 | c.-237C>A | upstream_gene_variant | 0.45 | isoniazid | |
hadA | 731696 | c.-233_-232delTT | upstream_gene_variant | 0.48 | isoniazid | |
hadA | 731708 | c.-221_-220delGA | upstream_gene_variant | 0.49 | isoniazid | |
hadA | 731717 | c.-213T>G | upstream_gene_variant | 0.47 | isoniazid | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.49 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.52 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.42 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.38 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.46 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.34 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.25 | isoniazid | |
hadA | 731840 | c.-90G>C | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.2 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.2 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.2 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.21 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.27 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.31 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.37 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.48 | isoniazid | |
hadA | 732389 | p.Ser154Thr | missense_variant | 0.48 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.48 | isoniazid | |
hadA | 732398 | p.Ala157Ile | missense_variant | 0.47 | isoniazid | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.23 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.24 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.25 | rifampicin | |
nusG | 734460 | c.207G>C | synonymous_variant | 0.25 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.31 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
nusG | 734478 | c.225C>T | synonymous_variant | 0.3 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734566 | c.313C>T | synonymous_variant | 0.29 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.27 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.28 | rifampicin | |
nusG | 734595 | c.342C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
nusG | 734610 | c.357C>G | synonymous_variant | 0.25 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.21 | rifampicin | |
nusG | 734680 | p.Ala143Thr | missense_variant | 0.18 | rifampicin | |
mmaA3 | 738260 | c.-117_-112delAATCCC | upstream_gene_variant | 1.0 | isoniazid | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760181 | c.375T>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760313 | c.507G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760358 | c.552C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760373 | c.567C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.2 | rifampicin | |
rpoB | 760388 | c.582C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760389 | c.583_584delAGinsTC | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760412 | c.606C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760415 | c.609C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760427 | c.621G>A | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760496 | c.690G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760508 | c.702G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760519 | p.Thr238Ser | missense_variant | 0.21 | rifampicin | |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.21 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.42 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760649 | c.843G>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.45 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.45 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760784 | c.978G>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760835 | c.1029delCinsTCACGCCCGTACG | conservative_inframe_insertion&synonymous_variant | 0.29 | rifampicin | |
rpoB | 760838 | p.Glu344Asp | missense_variant | 0.28 | rifampicin | |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.24 | rifampicin | |
rpoB | 760848 | p.Thr348Ala | missense_variant | 0.25 | rifampicin | |
rpoB | 760850 | c.1044delGinsTGTC | conservative_inframe_insertion&synonymous_variant | 0.25 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.4 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.45 | rifampicin | |
rpoB | 760910 | c.1104C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760922 | c.1116G>A | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761286 | c.1480C>T | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761289 | p.Ser495Ala | missense_variant | 0.32 | rifampicin | |
rpoB | 761292 | p.Val496Thr | missense_variant | 0.32 | rifampicin | |
rpoB | 761318 | c.1512G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761373 | p.Val523His | missense_variant | 0.22 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761434 | c.1629_1630delTG | frameshift_variant | 0.24 | rifampicin | |
rpoB | 761440 | c.1634_1635delACinsCAAG | frameshift_variant&missense_variant | 0.24 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.24 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.24 | rifampicin | |
rpoB | 761462 | c.1656C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761465 | c.1659G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761507 | c.1701G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761843 | c.2037C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761867 | c.2061C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.25 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.25 | rifampicin | |
rpoB | 761930 | c.2124G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.36 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762161 | c.2355C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.48 | rifampicin | |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.41 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762296 | c.2490G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.28 | rifampicin | |
rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762410 | c.2604T>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.29 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762548 | c.2742C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762971 | c.3165G>A | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.58 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.56 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 763049 | c.-321G>A | upstream_gene_variant | 0.54 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.41 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.41 | rifampicin | |
rpoC | 763163 | c.-207C>G | upstream_gene_variant | 0.39 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 763208 | c.-162T>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763220 | c.-150G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 763283 | c.3477T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763284 | c.-86C>T | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763304 | c.-66_-63delAAGTinsGTCC | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 763310 | c.-60C>T | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 763319 | c.-51T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 763322 | c.-48G>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 763325 | c.-44_-37delAGCTGTCG | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 763337 | c.-33_-32delAAinsCGTTTTCAG | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.26 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.26 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>A | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763648 | c.279C>T | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763663 | c.294C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.34 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763819 | c.450G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763835 | p.Ala156Thr | missense_variant | 0.32 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.29 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.32 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.29 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763885 | c.516C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763909 | c.540C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.23 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.3 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.29 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.4 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.42 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.51 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764254 | c.885G>A | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764293 | c.924G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764368 | c.999C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764719 | c.1350G>A | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764749 | c.1380G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764854 | c.1485G>A | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764858 | c.1489_1491delTTGinsCTA | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R |
rpoC | 765005 | c.1637_1638insGC | frameshift_variant | 0.27 | rifampicin | |
rpoC | 765010 | c.1641_1643delGAGinsC | frameshift_variant&missense_variant | 0.28 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765085 | c.1716T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765100 | c.1731G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765371 | c.2002C>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.37 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765415 | c.2046G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765452 | p.Ala695Ser | missense_variant | 0.42 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.43 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.4 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.4 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765946 | c.2577C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765947 | c.2578T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.3 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766061 | p.Val898Ile | missense_variant | 0.34 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.32 | rifampicin | |
rpoC | 766087 | c.2718C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766174 | p.Asn935Lys | missense_variant | 0.24 | rifampicin | |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.24 | rifampicin | |
rpoC | 766185 | p.Glu939Ala | missense_variant | 0.28 | rifampicin | |
rpoC | 766189 | c.2820T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766192 | c.2823T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766193 | p.Gln942Glu | missense_variant | 0.23 | rifampicin | |
rpoC | 766204 | c.2835C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766207 | c.2838T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766216 | c.2847T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766219 | p.Asp950Glu | missense_variant | 0.24 | rifampicin | |
rpoC | 766222 | c.2853T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766226 | c.2857T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766231 | c.2862T>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766234 | c.2865T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766237 | c.2868T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766240 | c.2871T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766243 | c.2874C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.32 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.32 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.51 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766462 | c.3093G>T | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.47 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.51 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.49 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.59 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.53 | rifampicin | |
rpoC | 766684 | c.3315C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766846 | c.3477C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766858 | c.3489C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766933 | c.3564A>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.51 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.5 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.51 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 767128 | c.3759C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.44 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpS5 | 778656 | p.Ala84Thr | missense_variant | 1.0 | bedaquiline | |
clofazimine | ||||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | bedaquiline | |
clofazimine | ||||||
rpsL | 781134 | c.-426T>A | upstream_gene_variant | 0.25 | streptomycin | |
rpsL | 781137 | c.-423G>C | upstream_gene_variant | 0.25 | streptomycin | |
rpsL | 781138 | c.-422_-421delCAinsGC | upstream_gene_variant | 0.25 | streptomycin | |
rpsL | 781143 | c.-417T>C | upstream_gene_variant | 0.26 | streptomycin | |
rpsL | 781158 | c.-402C>G | upstream_gene_variant | 0.27 | streptomycin | |
rpsL | 781161 | c.-399G>A | upstream_gene_variant | 0.27 | streptomycin | |
rpsL | 781164 | c.-396T>C | upstream_gene_variant | 0.27 | streptomycin | |
rpsL | 781173 | c.-387A>G | upstream_gene_variant | 0.27 | streptomycin | |
rpsL | 781179 | c.-381T>C | upstream_gene_variant | 0.28 | streptomycin | |
rpsL | 781182 | c.-378G>C | upstream_gene_variant | 0.29 | streptomycin | |
rpsL | 781185 | c.-375T>C | upstream_gene_variant | 0.29 | streptomycin | |
rpsL | 781197 | c.-363A>G | upstream_gene_variant | 0.31 | streptomycin | |
rpsL | 781206 | c.-354C>T | upstream_gene_variant | 0.29 | streptomycin | |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781406 | c.-154_-153insC | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.3 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781772 | c.213C>T | synonymous_variant | 0.42 | streptomycin | Not assoc w R - Interim |
rpsL | 781800 | c.241C>T | synonymous_variant | 0.44 | streptomycin | Not assoc w R - Interim |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.45 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.45 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.43 | streptomycin | Uncertain significance |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800797 | c.-12_-9delTTGGinsGTT | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.37 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.37 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.39 | linezolid | |
rplC | 800862 | c.54C>T | synonymous_variant | 0.36 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.37 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.37 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.35 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.34 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.34 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.39 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.38 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.37 | linezolid | |
rplC | 800910 | c.102C>T | synonymous_variant | 0.37 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.33 | linezolid | |
rplC | 800934 | c.126C>G | synonymous_variant | 0.3 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.29 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 0.29 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 800958 | c.150G>T | synonymous_variant | 0.29 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 0.31 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.32 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 0.27 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801004 | p.Leu66Val | missense_variant | 0.21 | linezolid | |
rplC | 801009 | c.201A>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.3 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.3 | linezolid | |
rplC | 801231 | c.423C>G | synonymous_variant | 0.31 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.24 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.24 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.2 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.24 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.26 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.25 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.26 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.28 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.3 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.28 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.27 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.24 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.25 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.26 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.3 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.29 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303538 | p.Arg203Leu | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303596 | c.666G>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303620 | c.690C>T | synonymous_variant | 0.25 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303623 | c.693C>T | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303626 | c.696C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303641 | c.711C>T | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303650 | c.720G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303653 | c.723G>A | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303654 | c.724C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303659 | c.729T>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303660 | p.Val244Thr | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303663 | c.733C>T | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303677 | c.747C>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.66 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303722 | c.792C>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Gly | missense_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303740 | c.810C>T | synonymous_variant | 0.32 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303779 | c.849G>A | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>T | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303812 | c.882C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303825 | p.Glu299Gln | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303833 | c.903C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303844 | p.Ala305Gly | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303851 | c.921C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303866 | c.936G>A | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303872 | c.942C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303873 | c.943C>T | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303878 | c.948G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303882 | p.Val318Met | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303893 | c.963G>A | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304706 | c.1776C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304766 | c.1836C>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304847 | c.1917C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304889 | c.1959G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304955 | c.2025G>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304960 | p.Arg677His | missense_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304970 | c.2040G>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304988 | c.2058G>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | p.Glu692Asp | missense_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305013 | p.Thr695Ser | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305039 | c.2109G>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305063 | c.2133G>A | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305066 | c.2136T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305069 | c.2139G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305078 | c.2148A>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305084 | c.2154C>T | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305092 | p.Ala721Gly | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305096 | c.2166T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305231 | c.2301C>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305240 | c.2310T>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305243 | c.2313T>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305252 | c.2322G>A | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305300 | c.2370A>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305303 | c.2373T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305331 | p.Glu801Asn | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305336 | c.2406T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305393 | c.2463T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
Rv1258c | 1407373 | c.-33A>G | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
pyrazinamide | ||||||
isoniazid | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.34 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 0.48 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.57 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.34 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473733 | n.76C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1473752 | n.95G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474953 | n.1296C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475243 | n.1586G>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475245 | n.1588T>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475247 | n.1592_1594delTCA | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475254 | n.1597delCinsTGAT | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475265 | n.1608G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475271 | n.1614A>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475273 | n.1616T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
inhA | 1673490 | c.-712A>G | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673523 | c.-679G>T | upstream_gene_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1673535 | c.-667A>G | upstream_gene_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1673568 | c.-634C>A | upstream_gene_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1673569 | c.-633G>A | upstream_gene_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.28 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1673596 | c.-606A>G | upstream_gene_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1673610 | c.-592C>T | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.2 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673710 | c.-492_-490delCTAinsATC | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673721 | c.-481C>T | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673724 | c.-478A>G | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673758 | c.-444A>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673862 | c.-340C>T | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673890 | c.-312G>T | upstream_gene_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1673901 | c.-301A>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673905 | c.-297T>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673916 | c.-286A>G | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1673925 | c.-277C>T | upstream_gene_variant | 0.3 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673941 | c.-261G>T | upstream_gene_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1673946 | c.-256C>G | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.35 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674006 | c.-196T>G | upstream_gene_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674015 | c.-187C>T | upstream_gene_variant | 0.35 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1674018 | c.-184G>C | upstream_gene_variant | 0.35 | isoniazid | |
ethionamide | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674033 | c.-169T>C | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674037 | c.-165C>G | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674042 | c.-160G>C | upstream_gene_variant | 0.33 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1674049 | c.-153_-151delCAAinsGAC | upstream_gene_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674054 | c.-148T>C | upstream_gene_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674060 | c.-142A>G | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674079 | c.-123C>G | upstream_gene_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674098 | c.-104T>C | upstream_gene_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674114 | c.-88T>C | upstream_gene_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674123 | c.-79T>C | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674126 | c.-76G>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674136 | c.-66T>G | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674141 | c.-61T>C | upstream_gene_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674507 | c.306G>A | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674514 | p.Ile105Val | missense_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.34 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Ala | missense_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>T | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674732 | c.531C>T | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674753 | c.552G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674789 | c.588G>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674795 | c.594G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.18 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.32 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833799 | c.258C>T | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833859 | c.318C>T | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833909 | p.Asp123Ala | missense_variant | 0.54 | pyrazinamide | Uncertain significance |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833976 | c.435C>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833982 | c.441C>T | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834018 | c.477C>T | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.32 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.32 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834252 | c.711C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGT | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834345 | c.804C>T | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834369 | c.828C>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834396 | c.855G>T | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834408 | c.867C>T | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834495 | c.954G>A | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834606 | c.1065C>T | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834619 | c.1078T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834630 | c.1089G>A | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.22 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.29 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.27 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853456 | c.-150C>T | upstream_gene_variant | 0.19 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.19 | linezolid | |
tsnR | 1853513 | c.-93C>T | upstream_gene_variant | 0.17 | linezolid | |
tsnR | 1853517 | c.-89G>A | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853525 | c.-81G>T | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853531 | c.-75A>G | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.33 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.3 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2102671 | c.372T>G | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102680 | c.363T>G | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102686 | c.357G>C | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102695 | c.348C>T | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102700 | c.343C>T | synonymous_variant | 0.28 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102710 | c.333C>T | synonymous_variant | 0.28 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102718 | p.Gln109Glu | missense_variant | 0.26 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102728 | c.315T>C | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102736 | c.307T>C | synonymous_variant | 0.28 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102737 | p.Glu102Asp | missense_variant | 0.28 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102743 | c.300C>G | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102750 | p.Cys98Phe | missense_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102754 | p.Gln97Lys | missense_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102755 | c.288G>C | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102758 | c.285C>T | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102779 | c.264C>T | synonymous_variant | 0.23 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.23 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.21 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.21 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.19 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.23 | isoniazid | |
kasA | 2518612 | c.498C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518656 | p.Ala181Gly | missense_variant | 0.26 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518699 | c.585C>T | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518843 | c.729T>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518897 | c.783G>A | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.21 | isoniazid | |
kasA | 2518921 | c.807T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2519029 | c.915C>T | synonymous_variant | 0.21 | isoniazid | |
eis | 2715744 | c.-413delA | upstream_gene_variant | 1.0 | kanamycin | |
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782546 | c.1497C>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Gln | missense_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.38 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.31 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.41 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.38 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.36 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.32 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783188 | c.855G>A | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783691 | c.352C>T | synonymous_variant | 0.5 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783695 | c.348C>T | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783770 | c.273G>A | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.42 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.44 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.32 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2752c | 3065421 | c.771G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065457 | c.735A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065460 | c.732G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065511 | c.681G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065517 | c.675C>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065520 | c.672G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065535 | c.657C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065553 | c.639A>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065562 | c.630T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065568 | p.Ile208Leu | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065576 | p.Ala206Ser | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065580 | c.612G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065586 | c.606C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065589 | c.603C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065595 | p.Leu199Phe | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065607 | c.585C>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066321 | c.-130C>T | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066360 | c.-169T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066369 | c.-180_-178delAGCinsGCG | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066380 | c.-189A>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066390 | c.-199C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066398 | c.-207G>A | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066399 | c.-210_-208delATTinsTCC | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066435 | c.-246_-244delGGTinsAAC | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066453 | c.-262G>A | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066456 | c.-265A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066462 | c.-271G>A | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066465 | c.-276_-274delGGGinsAAT | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066476 | c.-285C>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066477 | c.-286C>T | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066482 | c.-291G>T | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066507 | c.-316C>T | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066522 | c.-331C>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066561 | c.-370A>C | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066612 | c.-421G>A | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066618 | c.-427A>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066633 | c.-442T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066726 | c.-535C>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066734 | c.-543G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066861 | c.-670C>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067391 | c.555G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067427 | c.519G>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067462 | c.484C>T | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067463 | p.Ile161Val | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067472 | c.474C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067487 | c.459G>A | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067510 | c.436C>T | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067522 | p.Thr142Ala | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067711 | p.Ser79Thr | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067811 | c.135G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067856 | p.Asp30Glu | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074028 | c.444G>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074053 | p.Arg140Gln | missense_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074079 | c.393G>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074196 | c.276G>A | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074361 | c.111T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074372 | p.Met34Leu | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074379 | c.93C>T | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
lpqB | 3623484 | p.Phe476Tyr | missense_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623492 | c.1419T>C | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623512 | p.Gly467Ser | missense_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624166 | p.Met249Leu | missense_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624173 | c.738A>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624179 | c.732C>T | synonymous_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624182 | c.729C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624194 | c.717C>G | synonymous_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624200 | c.711A>G | synonymous_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624204 | p.Ser236Asn | missense_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624209 | c.702A>C | synonymous_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624224 | c.687T>C | synonymous_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624242 | c.669A>G | synonymous_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624245 | c.666A>G | synonymous_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624254 | c.657T>A | synonymous_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.42 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625762 | c.852A>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625777 | c.-867C>G | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.32 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
lpqB | 3625803 | c.-893C>T | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626765 | c.585C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.46 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.46 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626891 | c.-278G>A | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.42 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.41 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.36 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.49 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627056 | c.294C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627125 | c.-512C>G | upstream_gene_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.51 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627175 | c.175C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.49 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.49 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627196 | c.-583C>T | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.45 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.4 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877587 | p.Ser307Ala | missense_variant | 0.23 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.26 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.35 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3877689 | c.819C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877803 | c.705G>T | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.23 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878019 | c.489A>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878034 | c.474A>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3878046 | c.462T>A | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878256 | c.252G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.42 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878396 | c.112C>T | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878448 | c.60G>A | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878459 | p.Asn17Asp | missense_variant | 0.33 | rifampicin | |
rpoA | 3878465 | p.Thr15Ser | missense_variant | 0.35 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.35 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878759 | c.-252T>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.38 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.4 | rifampicin | Uncertain significance |
rpoA | 3878884 | c.-377C>G | upstream_gene_variant | 0.43 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.43 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.41 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.37 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.41 | rifampicin | Uncertain significance |
rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879007 | c.-500G>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879028 | c.-521C>T | upstream_gene_variant | 0.42 | rifampicin | |
rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879067 | c.-560G>A | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3879166 | c.-659C>G | upstream_gene_variant | 0.32 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.35 | pretomanid | |
delamanid | ||||||
ddn | 3986665 | c.-179G>C | upstream_gene_variant | 0.19 | pretomanid | |
delamanid | ||||||
ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 0.21 | pretomanid | |
delamanid | ||||||
ddn | 3986672 | c.-172G>A | upstream_gene_variant | 0.19 | pretomanid | |
delamanid | ||||||
ddn | 3986690 | c.-154C>G | upstream_gene_variant | 0.19 | pretomanid | |
delamanid | ||||||
ddn | 3987084 | p.Gly81Ser | missense_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038374 | c.2331C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.4 | pyrazinamide | |
clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.41 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.42 | pyrazinamide | |
clpC1 | 4038489 | p.Ala739Gly | missense_variant | 0.41 | pyrazinamide | |
clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.41 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.42 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>A | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4038602 | c.2103G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>A | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.41 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039208 | c.1497C>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.36 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039406 | c.1299G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.42 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039448 | c.1257A>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.25 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039925 | c.779_780delGCinsTCGAGG | frameshift_variant&synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039927 | c.774_777delTAGC | frameshift_variant | 0.36 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040087 | c.618G>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040090 | c.615T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040144 | c.561G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040207 | c.498T>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040228 | c.477G>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040345 | c.360C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040408 | c.297C>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040570 | c.135C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040573 | c.132T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040582 | c.123G>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040596 | c.109C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040600 | c.103_105delTTAinsCTG | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040657 | c.48T>G | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040674 | c.31A>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040675 | c.30C>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040678 | c.27C>A | synonymous_variant | 0.2 | pyrazinamide | |
panD | 4043865 | p.Gly139Arg | missense_variant | 0.2 | pyrazinamide | Uncertain significance |
panD | 4043872 | p.Gly137Val | missense_variant | 0.2 | pyrazinamide | Uncertain significance |
panD | 4043876 | p.Leu136Ile | missense_variant | 0.21 | pyrazinamide | |
panD | 4043883 | c.399C>T | synonymous_variant | 0.2 | pyrazinamide | |
panD | 4043886 | c.396A>C | synonymous_variant | 0.2 | pyrazinamide | |
panD | 4043896 | p.Gly129Ala | missense_variant | 0.2 | pyrazinamide | |
panD | 4043916 | c.366A>G | synonymous_variant | 0.19 | pyrazinamide | |
panD | 4043922 | c.360T>C | synonymous_variant | 0.18 | pyrazinamide | |
panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044788 | c.-507G>C | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.23 | pyrazinamide | |
panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.23 | pyrazinamide | |
panD | 4044844 | c.-563T>C | upstream_gene_variant | 0.28 | pyrazinamide | |
panD | 4044848 | c.-567T>G | upstream_gene_variant | 0.25 | pyrazinamide | |
panD | 4044854 | c.-573A>G | upstream_gene_variant | 0.25 | pyrazinamide | |
panD | 4044871 | c.-590C>T | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044892 | c.-611G>A | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044895 | c.-614A>T | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044896 | c.-615T>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044902 | c.-623_-621delACGinsGCC | upstream_gene_variant | 0.23 | pyrazinamide | |
panD | 4044908 | c.-628_-627delCTinsTC | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044917 | c.-636G>C | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044927 | c.-646C>A | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044936 | c.-655A>T | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044954 | c.-674_-673delCCinsAT | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044959 | c.-678C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044983 | c.-702G>C | upstream_gene_variant | 0.2 | pyrazinamide | |
glpK | 4138429 | c.1327T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138433 | c.1323C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138436 | c.1320C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138442 | c.1314C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138451 | c.1305T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138472 | c.1284G>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138478 | c.1278T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138481 | p.Val425Ala | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
glpK | 4138489 | c.1267T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138490 | c.1266G>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138495 | p.Gln421Glu | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138496 | c.1260G>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138502 | c.1254T>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138511 | c.1245C>T | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138514 | c.1242A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138518 | p.Glu413Ala | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138523 | c.1233C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138535 | c.1221T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138565 | c.1191G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138568 | c.1188A>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138571 | c.1185C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138580 | c.1176C>T | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138601 | c.1155G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138610 | c.1146C>T | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240277 | p.Leu139Val | missense_variant | 0.22 | ethambutol | |
embC | 4240284 | p.Thr141Ser | missense_variant | 0.22 | ethambutol | |
embC | 4240297 | c.435T>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4240307 | p.Gly149Ser | missense_variant | 0.28 | ethambutol | Uncertain significance |
embC | 4240313 | p.Thr151Ala | missense_variant | 0.22 | ethambutol | |
embC | 4240645 | c.783G>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.41 | ethambutol | Not assoc w R |
embC | 4240678 | c.816T>G | synonymous_variant | 0.44 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 0.56 | ethambutol | |
embC | 4240693 | c.831T>C | synonymous_variant | 0.39 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4240828 | c.966G>C | synonymous_variant | 0.44 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.44 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.52 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.49 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.51 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.49 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.46 | ethambutol | Not assoc w R |
embC | 4240898 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.46 | ethambutol | |
embC | 4240911 | p.Ala350Val | missense_variant | 0.49 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.43 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 0.43 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 0.42 | ethambutol | |
embC | 4240945 | c.1083T>G | synonymous_variant | 0.36 | ethambutol | |
embC | 4240954 | p.Ile364Met | missense_variant | 0.33 | ethambutol | |
embC | 4240957 | c.1095C>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4240966 | c.1104G>T | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embC | 4240969 | c.1107C>T | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embC | 4240971 | p.Ala370Val | missense_variant | 0.33 | ethambutol | |
embC | 4240979 | p.Thr373Gln | missense_variant | 0.34 | ethambutol | |
embC | 4240983 | p.Ser374Asn | missense_variant | 0.33 | ethambutol | |
embC | 4240987 | c.1125G>C | synonymous_variant | 0.33 | ethambutol | |
embC | 4240990 | c.1128A>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4240996 | c.1134G>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241002 | c.1140G>C | synonymous_variant | 0.35 | ethambutol | |
embC | 4241013 | p.Met384Thr | missense_variant | 0.38 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.38 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.39 | ethambutol | |
embC | 4241032 | c.1170G>C | synonymous_variant | 0.42 | ethambutol | |
embC | 4241038 | c.1176G>C | synonymous_variant | 0.39 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.38 | ethambutol | |
embC | 4241071 | c.1209C>G | synonymous_variant | 0.34 | ethambutol | |
embC | 4241081 | c.1219C>T | synonymous_variant | 0.31 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.28 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.28 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.23 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.24 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.24 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.27 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.96 | ethambutol | Not assoc w R |
embC | 4242762 | p.Arg967Gln | missense_variant | 0.21 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.19 | ethambutol | |
embA | 4242772 | c.-461G>C | upstream_gene_variant | 0.2 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.22 | ethambutol | |
embC | 4242791 | p.Ala977Ser | missense_variant | 0.2 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.2 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.22 | ethambutol | |
embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.23 | ethambutol | |
embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.25 | ethambutol | |
embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.24 | ethambutol | |
embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.24 | ethambutol | |
embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.23 | ethambutol | |
embA | 4242862 | c.-371A>G | upstream_gene_variant | 0.22 | ethambutol | |
embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.22 | ethambutol | |
embC | 4242883 | c.3021C>G | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embA | 4242892 | c.-341G>C | upstream_gene_variant | 0.24 | ethambutol | |
embA | 4242901 | c.-332G>C | upstream_gene_variant | 0.28 | ethambutol | |
embA | 4242919 | c.-314A>G | upstream_gene_variant | 0.3 | ethambutol | |
embC | 4242928 | c.3066A>G | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embA | 4242931 | c.-302G>C | upstream_gene_variant | 0.31 | ethambutol | |
embA | 4242940 | c.-293T>C | upstream_gene_variant | 0.31 | ethambutol | |
embC | 4242941 | p.His1027Asn | missense_variant | 0.27 | ethambutol | |
embA | 4242946 | c.-287T>C | upstream_gene_variant | 0.29 | ethambutol | |
embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4245315 | p.Val695Thr | missense_variant | 0.19 | ethambutol | |
embA | 4245340 | p.Gly703Ala | missense_variant | 0.2 | ethambutol | |
embA | 4245355 | p.Ala708Gly | missense_variant | 0.18 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4247455 | c.942C>T | synonymous_variant | 0.2 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4247476 | c.963C>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4247519 | c.1006C>T | synonymous_variant | 0.41 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.36 | ethambutol | |
embB | 4247544 | p.Ser344Thr | missense_variant | 0.36 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.31 | ethambutol | |
embB | 4247761 | c.1248T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247776 | c.1263G>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4247795 | c.1282_1284delCTCinsTTG | synonymous_variant | 0.33 | ethambutol | |
embB | 4247800 | c.1287A>G | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embB | 4247812 | c.1299G>C | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embB | 4247815 | c.1302C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4247819 | p.Val436Ile | missense_variant | 0.31 | ethambutol | Uncertain significance |
embB | 4247827 | c.1314C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
embB | 4247842 | c.1329T>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4247857 | c.1344C>G | synonymous_variant | 0.33 | ethambutol | |
embB | 4247858 | c.1345C>T | synonymous_variant | 0.34 | ethambutol | |
embB | 4247869 | c.1356G>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4247879 | p.Val456Ile | missense_variant | 0.39 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embB | 4247899 | p.Met462Ile | missense_variant | 0.43 | ethambutol | |
embB | 4247905 | c.1392G>A | synonymous_variant | 0.44 | ethambutol | |
embB | 4247908 | c.1395C>T | synonymous_variant | 0.41 | ethambutol | |
embB | 4247914 | c.1401G>C | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
embB | 4247923 | c.1410T>C | synonymous_variant | 0.45 | ethambutol | |
embB | 4247938 | c.1425G>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.39 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.4 | ethambutol | |
embB | 4247974 | c.1461C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4247992 | c.1479G>C | synonymous_variant | 0.41 | ethambutol | |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4248011 | p.Ser500Arg | missense_variant | 0.35 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 0.35 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 0.3 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.3 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.3 | ethambutol | |
embB | 4248052 | c.1539G>C | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4248055 | c.1542G>A | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.38 | ethambutol | |
embB | 4248101 | c.1588C>T | synonymous_variant | 0.38 | ethambutol | |
embB | 4248106 | c.1593C>T | synonymous_variant | 0.4 | ethambutol | Not assoc w R - Interim |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4248146 | p.Ile545Val | missense_variant | 0.34 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.34 | ethambutol | Not assoc w R - Interim |
embB | 4248160 | c.1647C>T | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4248169 | c.1656C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.37 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.37 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.37 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.37 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.41 | ethambutol | |
embB | 4248226 | c.1713G>C | synonymous_variant | 0.43 | ethambutol | |
embB | 4248295 | c.1782C>T | synonymous_variant | 0.43 | ethambutol | |
embB | 4248307 | c.1794G>C | synonymous_variant | 0.43 | ethambutol | |
embB | 4248313 | c.1800C>T | synonymous_variant | 0.43 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.41 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.41 | ethambutol | |
embB | 4248340 | c.1827G>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.34 | ethambutol | |
embB | 4248355 | c.1842A>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4248358 | c.1845_1850delCCCATCinsGCAT | frameshift_variant&missense_variant | 0.35 | ethambutol | |
embB | 4248397 | c.1884C>T | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4248407 | c.1894_1896delTTAinsCTG | synonymous_variant | 0.27 | ethambutol | |
embB | 4248416 | p.Leu635Val | missense_variant | 0.24 | ethambutol | |
embB | 4248424 | c.1911G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248432 | p.Trp640Phe | missense_variant | 0.23 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4249424 | c.2911C>T | synonymous_variant | 0.21 | ethambutol | |
embB | 4249432 | c.2919A>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4249441 | c.2928A>G | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
embB | 4249444 | c.2931T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4249447 | c.2934G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.32 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 0.38 | ethambutol | |
embB | 4249525 | c.3012T>C | synonymous_variant | 0.37 | ethambutol | Not assoc w R - Interim |
embB | 4249529 | p.Ile1006Val | missense_variant | 0.38 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.38 | ethambutol | Uncertain significance |
embB | 4249537 | c.3024A>G | synonymous_variant | 0.37 | ethambutol | |
embB | 4249546 | c.3033G>A | synonymous_variant | 0.37 | ethambutol | |
embB | 4249558 | c.3045A>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4249568 | p.Ser1019Asn | missense_variant | 0.26 | ethambutol | |
embB | 4249573 | c.3060T>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4249581 | p.Leu1023Gln | missense_variant | 0.25 | ethambutol | |
embB | 4249588 | c.3075C>G | synonymous_variant | 0.23 | ethambutol | |
embB | 4249594 | c.3081G>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4249598 | p.Glu1029Gln | missense_variant | 0.22 | ethambutol | |
embB | 4249607 | p.Thr1032Val | missense_variant | 0.23 | ethambutol | |
embB | 4249615 | c.3102C>T | synonymous_variant | 0.24 | ethambutol | |
embB | 4249627 | c.3114G>C | synonymous_variant | 0.23 | ethambutol | |
aftB | 4267647 | p.Asp397Gly | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269148 | p.Val229Ala | missense_variant | 0.94 | ethambutol | Uncertain significance |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |