TB-Profiler result

Run: SRR29096195
Summary

Run ID: SRR29096195

Sample name:

Date: 2025-02-11T09:59:12.235871

Number of reads: 20934

Percentage reads mapped: 26.25

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mshA 575821 c.474G>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575837 c.490C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155696 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155742 p.Gly124Arg missense_variant 1.0 isoniazid
katG 2155747 p.Ala122Gly missense_variant 1.0 isoniazid
katG 2155749 c.363C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 1.0 isoniazid
katG 2155764 p.His116Glu missense_variant 1.0 isoniazid
katG 2155769 p.Ile115Val missense_variant 1.0 isoniazid
katG 2155770 c.342C>G synonymous_variant 1.0 isoniazid
katG 2155782 c.330C>A synonymous_variant 1.0 isoniazid