Run ID: SRR5485511
Sample name:
Date: 18-08-2022 08:33:52
Number of reads: 229428
Percentage reads mapped: 99.24
Strain:
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
rpsL | 781687 | p.Lys43Arg | missense_variant | 1.0 | streptomycin |
rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.61 | kanamycin, capreomycin, aminoglycosides, amikacin |
rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.26 | kanamycin, capreomycin, aminoglycosides, amikacin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrB | 6645 | p.Ser469Asn | missense_variant | 0.18 |
rrs | 1472493 | n.648T>G | non_coding_transcript_exon_variant | 0.4 |
rrs | 1473206 | n.1361G>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.61 |
rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.59 |
rrs | 1473270 | n.1425G>A | non_coding_transcript_exon_variant | 0.61 |
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.61 |
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.61 |
rrs | 1473305 | n.1460G>T | non_coding_transcript_exon_variant | 0.65 |
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.26 |
fabG1 | 1673485 | p.Arg16Ser | missense_variant | 0.22 |
pncA | 2289319 | c.-78C>G | upstream_gene_variant | 0.2 |
eis | 2715282 | p.Phe17Leu | missense_variant | 0.17 |
embB | 4247468 | p.Tyr319His | missense_variant | 0.15 |