TB-Profiler result

Run: ERR176811
Summary

Run ID: ERR176811

Sample name:

Date: 31-03-2023 15:14:01

Number of reads: 1760966

Percentage reads mapped: 86.74

Strain: lineage4.9.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
lineage4.9.1 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8978 c.1677C>T synonymous_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.26
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.12
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.12
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 0.12
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.12
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.11
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.13
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.15
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.14
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.21
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.52
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.49
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.6
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.57
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.59
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.53
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.33
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.25
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.15
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.14
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.14
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.19
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.12
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.11
rrl 1474187 n.530T>C non_coding_transcript_exon_variant 0.11
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.11
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.1
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.1
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.11
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.12
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.17
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.14
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.14
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.14
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.12
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.22
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.21
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.22
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.38
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.47
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 0.49
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.5
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.46
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.54
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.52
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.54
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.54
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.5
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.51
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.42
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.42
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.4
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.33
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.26
Rv1979c 2223145 p.Arg7Lys missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289138 p.Leu35Arg missense_variant 1.0
pncA 2289448 c.-207G>A upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.35
ahpC 2726341 p.Val50Gly missense_variant 0.33
folC 2747263 c.336C>A synonymous_variant 0.2
ribD 2987307 p.Ala157Pro missense_variant 0.26
Rv2752c 3067191 c.-1000G>A upstream_gene_variant 0.97
thyA 3073806 c.666C>G synonymous_variant 0.33
fbiD 3339385 p.Asp90Asn missense_variant 1.0
rpoA 3878630 c.-123G>C upstream_gene_variant 0.17
rpoA 3878641 c.-134C>G upstream_gene_variant 0.16
clpC1 4038857 c.1848C>A synonymous_variant 0.3
embC 4242425 p.Arg855Gly missense_variant 0.28
whiB6 4338595 c.-75delG upstream_gene_variant 1.0