Run ID: ERR3275709
Sample name:
Date: 2024-10-05T01:48:15.643136
Number of reads: 5978981
Percentage reads mapped: 99.76
Median coverage: 76.0
Strain: lineage3
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3 | East-African-Indian | RD750 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | ||||
pyrazinamide | ||||
streptomycin | gid | c.115delC | Assoc w R | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
gid | 4408087 | c.115delC | frameshift_variant | 1.0 | streptomycin | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.13 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8909 | c.1608C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8913 | p.Lys538Arg | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8930 | c.1629C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>A | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8981 | c.1680G>C | synonymous_variant | 0.14 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.13 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8993 | c.1692C>T | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.13 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.13 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9596 | c.2295G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
Rv0010c | 13277 | c.282T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
nusG | 734354 | p.Pro34Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
nusG | 734472 | c.219T>C | synonymous_variant | 0.11 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.12 | rifampicin | |
nusG | 734508 | c.255C>G | synonymous_variant | 0.12 | rifampicin | |
nusG | 734753 | p.Thr167Met | missense_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 759746 | c.-61C>T | upstream_gene_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 760199 | c.393C>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760233 | c.427_429delAGTinsTCG | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760241 | c.435G>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760265 | p.Met153Ile | missense_variant | 0.14 | rifampicin | |
rpoB | 760274 | p.Glu156Asp | missense_variant | 0.12 | rifampicin | Uncertain significance |
rpoB | 760445 | c.639C>T | synonymous_variant | 0.11 | rifampicin | |
rpoB | 760457 | c.651C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760463 | c.657C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760511 | c.705G>C | synonymous_variant | 0.13 | rifampicin | |
rpoB | 760514 | c.708C>T | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.13 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.13 | rifampicin | |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761258 | c.1452G>A | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>C | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761318 | c.1512G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.11 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762080 | c.2274G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoB | 762137 | c.2331C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762170 | c.2364C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762173 | c.2367G>A | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762245 | c.2439G>T | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762434 | c.2628T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762881 | p.Met1025Ile | missense_variant | 0.15 | rifampicin | |
rpoC | 762896 | c.-474G>C | upstream_gene_variant | 0.14 | rifampicin | |
rpoB | 762899 | c.3093G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 762917 | c.-453C>A | upstream_gene_variant | 0.13 | rifampicin | |
rpoB | 762923 | c.3117C>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 762971 | c.-399G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763058 | c.-312C>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 763074 | p.Thr1090Val | missense_variant | 0.16 | rifampicin | |
rpoB | 763088 | c.3282C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763600 | c.231C>T | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 763606 | c.237C>G | synonymous_variant | 0.12 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.1 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.1 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoC | 764181 | p.Asp271Gly | missense_variant | 0.93 | rifampicin | Not assoc w R |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.12 | rifampicin | |
rpoC | 764509 | c.1140G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764533 | c.1164C>A | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764662 | c.1293G>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764746 | c.1377G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764758 | c.1389C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | p.His465Gln | missense_variant | 0.15 | rifampicin | |
rpoC | 764767 | c.1398G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>G | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764812 | p.Gln482Ala | missense_variant | 0.14 | rifampicin | |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764869 | c.1500C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>G | synonymous_variant | 0.12 | rifampicin | |
rpoC | 764878 | c.1509C>G | synonymous_variant | 0.12 | rifampicin | |
rpoC | 764887 | c.1518G>T | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764912 | p.Met515Gln | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764953 | c.1584G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764962 | c.1593G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765016 | c.1647C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765079 | c.1710T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765082 | c.1713G>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765085 | c.1716T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765094 | c.1725C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.14 | rifampicin | |
rpoC | 765892 | c.2523T>A | synonymous_variant | 0.13 | rifampicin | |
rpoC | 765908 | p.Leu847Ala | missense_variant | 0.15 | rifampicin | |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765946 | c.2577C>T | synonymous_variant | 0.12 | rifampicin | |
rpoC | 765947 | c.2578T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoC | 765952 | c.2583G>C | synonymous_variant | 0.12 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 766435 | p.Glu1022Asp | missense_variant | 0.13 | rifampicin | Uncertain significance |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 767012 | c.3643C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767059 | c.3690T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 767068 | c.3699G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767080 | c.3711G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767087 | p.Cys1240Ser | missense_variant | 0.26 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767106 | p.Asn1246Ile | missense_variant | 0.24 | rifampicin | |
rpoC | 767113 | c.3744G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 0.98 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471928 | n.83T>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471930 | n.85_89delGGAGAinsTTGCAGGG | non_coding_transcript_exon_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471936 | n.91A>G | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471979 | n.134T>C | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471980 | n.135G>T | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1471981 | n.136C>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472023 | n.178G>T | non_coding_transcript_exon_variant | 0.36 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 0.42 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472067 | n.222G>T | non_coding_transcript_exon_variant | 0.43 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472068 | n.223T>G | non_coding_transcript_exon_variant | 0.44 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.51 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472137 | n.292G>A | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472151 | n.306C>T | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472289 | n.444T>G | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472290 | n.445C>G | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472297 | n.453_461delGTCCGGGTT | non_coding_transcript_exon_variant | 0.24 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472309 | n.464C>T | non_coding_transcript_exon_variant | 0.23 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472314 | n.469_470delATinsG | non_coding_transcript_exon_variant | 0.23 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472324 | n.479G>C | non_coding_transcript_exon_variant | 0.23 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472325 | n.480G>C | non_coding_transcript_exon_variant | 0.23 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472439 | n.594C>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472445 | n.601dupT | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472449 | n.604_607delCACGinsGCA | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472462 | n.617T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472463 | n.618G>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472471 | n.626G>A | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472497 | n.652G>A | non_coding_transcript_exon_variant | 0.33 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472580 | n.735C>T | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472675 | n.830T>C | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472680 | n.835C>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472836 | n.991G>A | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472840 | n.995A>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472841 | n.996G>A | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472848 | n.1003T>A | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472859 | n.1014G>T | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472873 | n.1028C>T | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472874 | n.1029C>T | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472875 | n.1030T>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472880 | n.1035G>A | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472958 | n.1113A>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472960 | n.1115G>A | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472986 | n.1141C>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472988 | n.1143T>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473743 | n.86C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1473750 | n.93C>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473757 | n.100T>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473768 | n.111A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473811 | n.154C>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473812 | n.155G>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473828 | n.171_172insCT | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473835 | n.179delA | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1473844 | n.187C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473870 | n.213G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474529 | n.872A>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474530 | n.873G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474539 | n.882C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474540 | n.883T>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474626 | n.969T>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474628 | n.971C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474709 | n.1053_1056delTGGT | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060_1061insGTGAG | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474721 | n.1064G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474722 | n.1065T>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474723 | n.1066G>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474740 | n.1083G>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474747 | n.1090C>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474903 | n.1246T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474932 | n.1275C>T | non_coding_transcript_exon_variant | 0.12 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 0.12 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475059 | n.1404_1405delCA | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475064 | n.1407G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1475067 | n.1410_1411insG | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475076 | n.1419C>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475079 | n.1422T>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475080 | n.1423G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475081 | n.1424C>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475088 | n.1431A>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475090 | n.1433A>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475114 | n.1457C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475116 | n.1459G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475767 | n.2110G>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476105 | n.2450delA | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.54 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.5 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>A | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476309 | n.2652G>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476607 | n.2950C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476661 | n.3004A>G | non_coding_transcript_exon_variant | 0.12 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833589 | c.48A>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833595 | c.54T>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.15 | pyrazinamide | |
rpsA | 1833616 | c.75A>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833623 | p.Lys28Ser | missense_variant | 0.16 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833676 | c.135A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833679 | c.138G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833685 | c.144G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833694 | c.153G>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833697 | c.156C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833709 | c.168C>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833763 | c.222C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833781 | c.240T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833782 | p.Ser81Asn | missense_variant | 0.2 | pyrazinamide | |
rpsA | 1833799 | c.258C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833805 | c.264C>A | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833859 | c.318C>T | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833877 | c.336C>G | synonymous_variant | 0.11 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.16 | pyrazinamide | |
rpsA | 1833904 | c.363G>A | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833970 | c.429G>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833976 | c.435C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833985 | c.444G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833988 | c.447C>G | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833991 | c.450C>A | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.11 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834399 | p.His286Gln | missense_variant | 0.12 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834423 | c.882G>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834432 | c.891G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834483 | p.Glu314Asp | missense_variant | 0.22 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834519 | c.978G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834540 | c.999G>T | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834552 | c.1011G>T | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Pro | missense_variant | 0.12 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.12 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
PPE35 | 2170769 | c.-157C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
pncA | 2289047 | c.195C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
pncA | 2289365 | c.-125delC | upstream_gene_variant | 1.0 | pyrazinamide | |
ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R |
Rv2477c | 2782498 | c.1545C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
rpoA | 3877734 | c.774G>C | synonymous_variant | 0.12 | rifampicin | |
clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038795 | p.Ser637Thr | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038810 | p.Gln632Ser | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038839 | c.1866G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038905 | c.1800A>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039088 | c.1617G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039091 | c.1614G>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039094 | c.1611C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039181 | c.1522_1524delTTGinsCTC | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039187 | c.1518G>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039199 | p.Ala502Glu | missense_variant | 0.15 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039654 | p.Thr351Ser | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039691 | c.1014G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>A | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039787 | c.916_918delTCGinsAGC | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039829 | c.874_876delTTGinsCTC | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039832 | c.873C>G | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039889 | c.816G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039996 | p.Glu237Lys | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4040002 | p.His235Asn | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4040003 | c.702G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040009 | c.696C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040018 | c.687G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.21 | pyrazinamide | |
panD | 4044872 | c.-591C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
glpK | 4138622 | c.1134C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
embC | 4242075 | p.Arg738Gln | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |