TB-Profiler result

Run: ERR3445487
Summary

Run ID: ERR3445487

Sample name:

Date: 01-04-2023 02:12:51

Number of reads: 1199657

Percentage reads mapped: 40.8

Strain: La1.7.X-unk4

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 0.99
La1.7 M.bovis None None 1.0
La1.7.X-unk4 M.bovis None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.68 streptomycin
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7607 c.306C>T synonymous_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 760235 c.429T>C synonymous_variant 0.16
rpoB 760244 c.438G>C synonymous_variant 0.16
rpoB 760916 c.1110C>T synonymous_variant 0.14
rpoB 760925 c.1119T>C synonymous_variant 0.13
rpoB 760946 c.1140A>G synonymous_variant 0.16
rpoB 760973 c.1167G>C synonymous_variant 0.12
rpoB 761015 c.1209G>C synonymous_variant 0.17
rpoB 761027 c.1221A>G synonymous_variant 0.17
rpoB 761036 c.1230G>C synonymous_variant 0.16
rpoB 761102 c.1296A>G synonymous_variant 0.19
rpoB 761132 c.1326G>C synonymous_variant 0.14
rpoB 761133 c.1327T>C synonymous_variant 0.2
rpoB 761150 c.1344A>T synonymous_variant 0.16
rpoB 761189 c.1383T>C synonymous_variant 0.16
rpoB 761195 c.1389G>C synonymous_variant 0.22
rpoB 761198 c.1392G>C synonymous_variant 0.16
rpoB 761234 c.1428G>C synonymous_variant 0.17
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761537 c.1731C>G synonymous_variant 0.18
rpoB 761555 c.1749G>C synonymous_variant 0.3
rpoB 761558 c.1752C>G synonymous_variant 0.32
rpoB 761561 c.1755C>G synonymous_variant 0.29
rpoB 761565 p.Met587Leu missense_variant 0.29
rpoB 761570 c.1764T>C synonymous_variant 0.32
rpoB 761573 c.1767C>G synonymous_variant 0.35
rpoB 761600 c.1794T>C synonymous_variant 0.36
rpoB 761603 c.1797C>G synonymous_variant 0.32
rpoB 761613 p.Ala603Ser missense_variant 0.28
rpoB 761631 p.Ala609Ser missense_variant 0.28
rpoB 761643 p.Val613Ile missense_variant 0.27
rpoB 761648 c.1842T>C synonymous_variant 0.34
rpoB 761650 p.Ser615Asn missense_variant 0.27
rpoB 761654 p.Glu616Asp missense_variant 0.28
rpoB 761663 c.1857G>C synonymous_variant 0.24
rpoB 761666 c.1860G>C synonymous_variant 0.31
rpoB 761675 c.1869G>C synonymous_variant 0.19
rpoB 761682 c.1876C>T synonymous_variant 0.21
rpoB 761687 c.1881C>T synonymous_variant 0.18
rpoB 761693 c.1887G>C synonymous_variant 0.17
rpoB 761967 p.Glu721Gln missense_variant 0.16
rpoB 761999 c.2193G>C synonymous_variant 0.16
rpoB 762002 c.2196C>G synonymous_variant 0.16
rpoB 762003 p.Asn733Gln missense_variant 0.14
rpoB 762009 p.Leu735Val missense_variant 0.13
rpoB 762015 p.Glu737Gln missense_variant 0.13
rpoB 762020 p.Glu738Asp missense_variant 0.14
rpoB 762024 p.Val740Leu missense_variant 0.16
rpoB 762029 c.2223C>G synonymous_variant 0.16
rpoB 762053 c.2247T>C synonymous_variant 0.22
rpoB 762057 p.Ile751Val missense_variant 0.19
rpoB 762062 c.2256T>C synonymous_variant 0.21
rpoB 762065 c.2259T>C synonymous_variant 0.24
rpoB 762083 c.2277T>C synonymous_variant 0.27
rpoB 762084 p.Ala760Pro missense_variant 0.23
rpoB 762114 p.Ile770Val missense_variant 0.27
rpoB 762117 c.2311_2312delTCinsAG synonymous_variant 0.21
rpoB 762126 p.Val774Met missense_variant 0.3
rpoB 762140 c.2334G>C synonymous_variant 0.3
rpoB 762143 c.2337T>C synonymous_variant 0.29
rpoB 762149 c.2343G>C synonymous_variant 0.29
rpoB 762156 p.Val784Ile missense_variant 0.27
rpoB 762167 c.2361T>C synonymous_variant 0.28
rpoB 762176 c.2370T>C synonymous_variant 0.25
rpoB 762177 p.Arg791Ser missense_variant 0.24
rpoB 762180 p.Asp792Asn missense_variant 0.23
rpoB 762185 c.2379G>C synonymous_variant 0.25
rpoB 762194 c.2388G>C synonymous_variant 0.26
rpoB 762218 c.2412T>C synonymous_variant 0.23
rpoB 762233 c.2427G>C synonymous_variant 0.23
rpoB 762236 c.2430G>C synonymous_variant 0.22
rpoB 762245 c.2439G>C synonymous_variant 0.23
rpoB 762251 c.2445G>C synonymous_variant 0.2
rpoB 762254 c.2448T>C synonymous_variant 0.2
rpoB 762257 c.2451C>G synonymous_variant 0.18
rpoB 762387 p.Glu861Gln missense_variant 0.12
rpoC 762410 c.-960T>G upstream_gene_variant 0.15
rpoC 762416 c.-954A>G upstream_gene_variant 0.14
rpoC 762443 c.-927G>C upstream_gene_variant 0.14
rpoB 762849 p.Tyr1015Asp missense_variant 0.21
rpoB 762855 p.Val1017Ile missense_variant 0.21
rpoB 762858 p.Thr1018Ser missense_variant 0.21
rpoC 762863 c.-507T>C upstream_gene_variant 0.22
rpoB 762879 p.Met1025Leu missense_variant 0.27
rpoC 762899 c.-471G>C upstream_gene_variant 0.33
rpoC 762923 c.-447C>G upstream_gene_variant 0.38
rpoC 762929 c.-441G>C upstream_gene_variant 0.4
rpoC 762956 c.-414G>C upstream_gene_variant 0.46
rpoC 762962 c.-408C>T upstream_gene_variant 0.45
rpoC 762983 c.-387C>A upstream_gene_variant 0.35
rpoC 762989 c.-381G>C upstream_gene_variant 0.35
rpoC 762995 c.-375G>T upstream_gene_variant 0.35
rpoB 763005 p.Cys1067Val missense_variant 0.23
rpoB 763014 p.Met1070Leu missense_variant 0.2
rpoB 763017 p.Gln1071Glu missense_variant 0.22
rpoC 763022 c.-348C>G upstream_gene_variant 0.21
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763034 c.-336C>G upstream_gene_variant 0.24
rpoB 763038 p.Thr1078Ala missense_variant 0.26
rpoC 763052 c.-318G>C upstream_gene_variant 0.24
rpoC 763053 c.-317T>C upstream_gene_variant 0.32
rpoC 763067 c.-303C>G upstream_gene_variant 0.21
rpoC 763070 c.-300T>C upstream_gene_variant 0.28
rpoB 763075 p.Thr1090Ile missense_variant 0.23
rpoB 763077 p.Val1091Leu missense_variant 0.2
rpoC 763082 c.-288C>A upstream_gene_variant 0.2
rpoC 763462 c.93G>C synonymous_variant 0.2
rpoC 763486 c.117T>C synonymous_variant 0.34
rpoC 763492 c.123G>C synonymous_variant 0.33
rpoC 763496 p.Lys43Arg missense_variant 0.31
rpoC 763528 c.159G>T synonymous_variant 0.48
rpoC 763531 c.162G>C synonymous_variant 0.48
rpoC 763534 c.165T>C synonymous_variant 0.49
rpoC 763537 c.168C>G synonymous_variant 0.53
rpoC 763546 c.177A>G synonymous_variant 0.6
rpoC 763570 c.201G>T synonymous_variant 0.61
rpoC 763573 c.204G>C synonymous_variant 0.62
rpoC 763622 p.Ala85Ser missense_variant 0.49
rpoC 763633 c.264T>C synonymous_variant 0.51
rpoC 763642 c.273G>C synonymous_variant 0.48
rpoC 763648 c.279C>A synonymous_variant 0.46
rpoC 763660 c.291T>C synonymous_variant 0.41
rpoC 763666 c.297G>T synonymous_variant 0.41
rpoC 764308 c.939G>C synonymous_variant 0.19
rpoC 764317 c.948C>G synonymous_variant 0.19
rpoC 764326 c.957G>C synonymous_variant 0.23
rpoC 764353 c.984G>C synonymous_variant 0.36
rpoC 764365 c.996C>T synonymous_variant 0.33
rpoC 764371 c.1002G>C synonymous_variant 0.34
rpoC 764380 c.1011G>C synonymous_variant 0.34
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.32
rpoC 764387 c.1018T>C synonymous_variant 0.38
rpoC 764398 c.1029G>C synonymous_variant 0.31
rpoC 764404 c.1035C>T synonymous_variant 0.36
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.42
rpoC 764410 c.1041G>C synonymous_variant 0.36
rpoC 764431 c.1062G>C synonymous_variant 0.38
rpoC 764434 c.1065A>G synonymous_variant 0.38
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.38
rpoC 764441 p.Ile358Leu missense_variant 0.33
rpoC 764446 c.1077T>C synonymous_variant 0.36
rpoC 764449 c.1080G>C synonymous_variant 0.36
rpoC 764452 c.1083T>C synonymous_variant 0.31
rpoC 764461 c.1092A>G synonymous_variant 0.42
rpoC 764491 c.1122G>C synonymous_variant 0.38
rpoC 764497 c.1128A>G synonymous_variant 0.37
rpoC 764498 p.Ser377Ala missense_variant 0.29
rpoC 764503 c.1134G>C synonymous_variant 0.31
rpoC 764507 p.Ala380Ser missense_variant 0.32
rpoC 764521 c.1152T>C synonymous_variant 0.38
rpoC 764527 c.1158C>T synonymous_variant 0.39
rpoC 764530 c.1161C>T synonymous_variant 0.36
rpoC 764536 c.1167G>T synonymous_variant 0.33
rpoC 764566 c.1197C>G synonymous_variant 0.5
rpoC 764573 p.Leu402Ile missense_variant 0.47
rpoC 764581 c.1212T>C synonymous_variant 0.47
rpoC 764582 p.Leu405Met missense_variant 0.48
rpoC 764602 c.1233C>T synonymous_variant 0.59
rpoC 764605 c.1236G>C synonymous_variant 0.58
rpoC 764611 c.1242G>T synonymous_variant 0.59
rpoC 764632 c.1263T>C synonymous_variant 0.6
rpoC 764647 c.1278C>T synonymous_variant 0.61
rpoC 764650 c.1281G>A synonymous_variant 0.62
rpoC 764662 c.1293G>C synonymous_variant 0.6
rpoC 764665 c.1296C>T synonymous_variant 0.6
rpoC 764701 c.1332C>G synonymous_variant 0.54
rpoC 764706 p.Leu446Gln missense_variant 0.49
rpoC 764714 p.Leu449Ile missense_variant 0.49
rpoC 764737 c.1368G>C synonymous_variant 0.49
rpoC 764752 c.1383G>C synonymous_variant 0.48
rpoC 764764 c.1395T>C synonymous_variant 0.49
rpoC 764767 c.1398G>T synonymous_variant 0.46
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.39
rpoC 764791 c.1422C>G synonymous_variant 0.38
rpoC 764824 c.1455T>C synonymous_variant 0.32
rpoC 764827 c.1458G>C synonymous_variant 0.36
rpoC 764854 c.1485G>C synonymous_variant 0.29
rpoC 764858 c.1489T>C synonymous_variant 0.31
rpoC 764863 c.1494G>C synonymous_variant 0.26
rpoC 764869 c.1500C>T synonymous_variant 0.23
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781760 c.201T>C synonymous_variant 0.18
rpsL 781766 c.207C>T synonymous_variant 0.22
rpsL 781772 c.213C>T synonymous_variant 0.22
rpsL 781796 p.Met79Ile missense_variant 0.22
rpsL 781802 c.243G>C synonymous_variant 0.21
rpsL 781808 c.249C>T synonymous_variant 0.21
rpsL 781817 c.258G>T synonymous_variant 0.23
rpsL 781829 c.270G>C synonymous_variant 0.21
rpsL 781832 c.273T>G synonymous_variant 0.2
rpsL 781838 c.279G>C synonymous_variant 0.22
rpsL 781841 c.282C>A synonymous_variant 0.19
rpsL 781856 c.297C>T synonymous_variant 0.18
rpsL 781859 c.300T>C synonymous_variant 0.18
rpsL 781860 p.Ser101Ala missense_variant 0.18
rpsL 781868 c.309T>C synonymous_variant 0.18
rpsL 781871 c.312G>C synonymous_variant 0.19
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
embR 1416666 p.Tyr228His missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.19
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.48
rrs 1472114 n.269A>G non_coding_transcript_exon_variant 0.49
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.6
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.57
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.51
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.49
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.43
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.42
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.4
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.15
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.27
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.13
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.24
rrs 1472508 n.663T>C non_coding_transcript_exon_variant 0.24
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.51
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.51
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.5
rrs 1472583 n.738T>G non_coding_transcript_exon_variant 0.5
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.51
rrs 1472585 n.740A>T non_coding_transcript_exon_variant 0.51
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.61
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.66
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.61
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.61
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.64
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.62
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.63
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.63
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.63
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.67
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.69
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.66
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.38
rrs 1472791 n.946G>T non_coding_transcript_exon_variant 0.38
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.23
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.33
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.67
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.72
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.72
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.72
rrs 1473065 n.1220C>A non_coding_transcript_exon_variant 0.65
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.65
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.63
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.66
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.62
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.65
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.65
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.63
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.64
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.65
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.67
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.71
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.7
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.64
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.63
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.63
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.13
rrl 1474166 n.509G>T non_coding_transcript_exon_variant 0.14
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.38
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.38
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.4
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.43
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.38
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.23
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.21
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.21
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.19
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.13
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.13
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.16
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.14
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.42
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.43
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.44
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.49
rrl 1474534 n.877G>A non_coding_transcript_exon_variant 0.42
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.43
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.43
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.41
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.22
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.38
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.44
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.44
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.44
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.44
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.45
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.56
rrl 1474800 n.1143T>G non_coding_transcript_exon_variant 0.51
rrl 1474801 n.1144G>T non_coding_transcript_exon_variant 0.53
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.58
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.57
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.57
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.33
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.35
rrl 1474917 n.1260G>T non_coding_transcript_exon_variant 0.34
rrl 1474934 n.1277C>A non_coding_transcript_exon_variant 0.17
rrl 1474935 n.1278A>T non_coding_transcript_exon_variant 0.17
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.23
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.23
rrl 1475080 n.1423G>T non_coding_transcript_exon_variant 0.24
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.23
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.32
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.34
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.32
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.32
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.32
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.32
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.32
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.32
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.35
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.22
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.14
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.35
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.25
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.25
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.33
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.33
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.26
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.26
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.27
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.21
rrl 1475602 n.1945G>T non_coding_transcript_exon_variant 0.18
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.3
rrl 1475697 n.2040C>A non_coding_transcript_exon_variant 0.29
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.29
rrl 1475702 n.2045G>T non_coding_transcript_exon_variant 0.29
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.3
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.41
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.46
rrl 1475752 n.2095C>G non_coding_transcript_exon_variant 0.45
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.5
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.51
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.53
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.46
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.47
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.46
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.51
rrl 1475880 n.2223C>G non_coding_transcript_exon_variant 0.49
rrl 1475881 n.2224T>G non_coding_transcript_exon_variant 0.49
rrl 1475882 n.2225C>G non_coding_transcript_exon_variant 0.49
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.48
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.48
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.51
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.51
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.5
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.51
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.54
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.48
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.42
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.36
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.33
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.36
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.36
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.21
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.18
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.18
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.18
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.19
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.19
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.17
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.19
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.35
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.48
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.44
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.45
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.51
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.53
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.41
rrl 1476248 n.2591G>C non_coding_transcript_exon_variant 0.4
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.41
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.38
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.38
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.41
rrl 1476259 n.2602C>G non_coding_transcript_exon_variant 0.4
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.46
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.48
rrl 1476288 n.2631T>C non_coding_transcript_exon_variant 0.3
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.3
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.29
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.33
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.3
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.3
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.3
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.36
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.38
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.58
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.51
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.51
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.53
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.53
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.56
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.39
rpsA 1833646 c.105T>C synonymous_variant 0.17
rpsA 1833649 c.108C>T synonymous_variant 0.16
rpsA 1833661 p.Glu40Asp missense_variant 0.2
rpsA 1833676 c.135A>G synonymous_variant 0.21
rpsA 1833679 c.138G>C synonymous_variant 0.18
rpsA 1833682 c.141C>T synonymous_variant 0.19
rpsA 1833685 c.144G>T synonymous_variant 0.19
rpsA 1833694 c.153G>C synonymous_variant 0.23
rpsA 1833724 c.183C>T synonymous_variant 0.26
rpsA 1833727 c.186G>C synonymous_variant 0.26
rpsA 1833730 c.189C>T synonymous_variant 0.26
rpsA 1833734 p.Ala65Ser missense_variant 0.26
rpsA 1833739 c.198C>G synonymous_variant 0.22
rpsA 1833742 c.201A>G synonymous_variant 0.22
rpsA 1833770 p.Asn77His missense_variant 0.19
rpsA 1833781 c.240T>C synonymous_variant 0.14
rpsA 1833790 c.249T>C synonymous_variant 0.12
rpsA 1833829 c.288A>G synonymous_variant 0.13
rpsA 1833835 c.294C>G synonymous_variant 0.13
rpsA 1833838 c.297G>T synonymous_variant 0.13
rpsA 1833841 c.300C>G synonymous_variant 0.16
rpsA 1833850 c.309C>G synonymous_variant 0.16
rpsA 1833856 c.315A>G synonymous_variant 0.24
rpsA 1833859 c.318C>G synonymous_variant 0.19
rpsA 1833874 c.333T>C synonymous_variant 0.29
rpsA 1833884 p.Thr115Asp missense_variant 0.26
rpsA 1833893 p.Ala118Lys missense_variant 0.25
rpsA 1833896 p.Leu119Ile missense_variant 0.28
rpsA 1833904 p.Glu121Asp missense_variant 0.26
rpsA 1833905 p.Lys122Glu missense_variant 0.27
rpsA 1833912 p.Glu124Gly missense_variant 0.28
rpsA 1833915 p.Ala125Val missense_variant 0.26
rpsA 1833920 p.Lys127Glu missense_variant 0.27
rpsA 1833928 c.387G>C synonymous_variant 0.36
rpsA 1833949 c.408T>C synonymous_variant 0.42
rpsA 1833955 c.414G>C synonymous_variant 0.36
rpsA 1833970 c.429G>T synonymous_variant 0.4
rpsA 1833976 c.435C>T synonymous_variant 0.34
rpsA 1833979 c.438T>C synonymous_variant 0.38
rpsA 1833991 c.450C>G synonymous_variant 0.34
rpsA 1833997 c.456G>C synonymous_variant 0.31
rpsA 1834000 c.459G>C synonymous_variant 0.35
rpsA 1834009 c.468C>T synonymous_variant 0.31
rpsA 1834012 c.471G>C synonymous_variant 0.29
rpsA 1834015 c.474G>C synonymous_variant 0.3
rpsA 1834025 p.Gln162Ala missense_variant 0.27
rpsA 1834030 c.489C>G synonymous_variant 0.29
rpsA 1834034 p.Ile165Val missense_variant 0.27
rpsA 1834040 p.Lys167Gln missense_variant 0.27
rpsA 1834043 p.Glu168Lys missense_variant 0.27
rpsA 1834046 p.Ile169Leu missense_variant 0.27
rpsA 1834054 c.513C>G synonymous_variant 0.27
rpsA 1834069 c.528G>C synonymous_variant 0.29
rpsA 1834093 c.552G>C synonymous_variant 0.17
rpsA 1834099 c.558C>G synonymous_variant 0.15
rpsA 1834210 c.669C>T synonymous_variant 0.17
rpsA 1834222 c.681T>C synonymous_variant 0.21
rpsA 1834240 c.699T>A synonymous_variant 0.24
rpsA 1834243 c.702G>C synonymous_variant 0.25
rpsA 1834246 c.705G>C synonymous_variant 0.26
rpsA 1834249 c.708T>C synonymous_variant 0.34
rpsA 1834261 c.720A>G synonymous_variant 0.35
rpsA 1834294 c.753G>C synonymous_variant 0.39
rpsA 1834303 c.762T>G synonymous_variant 0.46
rpsA 1834306 c.765T>C synonymous_variant 0.47
rpsA 1834318 c.777C>G synonymous_variant 0.45
rpsA 1834327 c.786G>C synonymous_variant 0.42
rpsA 1834348 c.807T>C synonymous_variant 0.35
rpsA 1834354 c.813G>C synonymous_variant 0.31
rpsA 1834357 c.816T>C synonymous_variant 0.33
rpsA 1834361 c.820T>C synonymous_variant 0.36
rpsA 1834366 c.825A>G synonymous_variant 0.35
rpsA 1834369 c.828C>G synonymous_variant 0.33
rpsA 1834378 c.837T>C synonymous_variant 0.4
rpsA 1834384 c.843A>G synonymous_variant 0.43
rpsA 1834387 c.846C>T synonymous_variant 0.45
rpsA 1834395 p.Arg285Gln missense_variant 0.46
rpsA 1834408 c.867C>G synonymous_variant 0.44
rpsA 1834411 c.870T>C synonymous_variant 0.5
rpsA 1834415 p.Ala292Gln missense_variant 0.47
rpsA 1834423 c.882G>C synonymous_variant 0.52
rpsA 1834432 c.891G>C synonymous_variant 0.45
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.43
rpsA 1834456 c.915T>C synonymous_variant 0.38
rpsA 1834468 c.927A>G synonymous_variant 0.38
rpsA 1834474 c.933C>G synonymous_variant 0.35
rpsA 1834489 c.948T>C synonymous_variant 0.46
rpsA 1834513 c.972C>G synonymous_variant 0.42
rpsA 1834519 c.978G>C synonymous_variant 0.29
rpsA 1834606 c.1065C>T synonymous_variant 0.16
rpsA 1834609 c.1068T>C synonymous_variant 0.16
rpsA 1834619 c.1078T>C synonymous_variant 0.16
rpsA 1834633 c.1092A>G synonymous_variant 0.17
rpsA 1834639 c.1098T>C synonymous_variant 0.18
rpsA 1834654 c.1113G>A synonymous_variant 0.15
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168814 c.1798dupA frameshift_variant 1.0
PPE35 2170066 p.Ala183Thr missense_variant 0.12
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
folC 2746171 c.1428G>A synonymous_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4039090 c.1615C>T synonymous_variant 0.14
clpC1 4039091 c.1614G>T synonymous_variant 0.16
clpC1 4039097 c.1608G>T synonymous_variant 0.14
clpC1 4039103 c.1602T>C synonymous_variant 0.13
clpC1 4039106 c.1599G>C synonymous_variant 0.13
clpC1 4039112 c.1593C>G synonymous_variant 0.14
clpC1 4039559 c.1146C>G synonymous_variant 0.19
clpC1 4039570 p.Met379Leu missense_variant 0.19
clpC1 4039577 c.1128T>C synonymous_variant 0.19
clpC1 4039588 p.Ser373Thr missense_variant 0.16
clpC1 4039610 c.1095G>T synonymous_variant 0.17
clpC1 4039616 c.1089G>T synonymous_variant 0.23
clpC1 4039631 p.Ile358Met missense_variant 0.17
clpC1 4039670 c.1035G>C synonymous_variant 0.14
clpC1 4039697 c.1008C>G synonymous_variant 0.13
clpC1 4039714 p.Tyr331His missense_variant 0.13
clpC1 4040087 c.618G>C synonymous_variant 0.17
clpC1 4040090 c.615T>G synonymous_variant 0.17
clpC1 4040105 c.600C>G synonymous_variant 0.15
clpC1 4040129 c.576C>G synonymous_variant 0.12
clpC1 4040267 c.438A>G synonymous_variant 0.17
clpC1 4040273 c.432T>C synonymous_variant 0.15
clpC1 4040291 c.414G>C synonymous_variant 0.15
clpC1 4040306 c.399G>C synonymous_variant 0.14
clpC1 4040411 c.294T>C synonymous_variant 0.18
clpC1 4040423 c.282A>G synonymous_variant 0.18
clpC1 4040429 c.274_276delTTGinsCTC synonymous_variant 0.16
clpC1 4040435 c.270G>C synonymous_variant 0.16
clpC1 4040450 c.255A>G synonymous_variant 0.18
clpC1 4040456 c.249C>T synonymous_variant 0.14
clpC1 4040459 c.246C>G synonymous_variant 0.17
clpC1 4040465 c.240T>C synonymous_variant 0.16
clpC1 4040471 c.234T>C synonymous_variant 0.19
clpC1 4040477 c.228G>C synonymous_variant 0.14
clpC1 4040480 c.223_225delTCTinsAGC synonymous_variant 0.2
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 0.98
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4267034 c.1803C>T synonymous_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0