TB-Profiler result

Run: ERR4178216
Summary

Run ID: ERR4178216

Sample name:

Date: 01-04-2023 04:36:00

Number of reads: 1988385

Percentage reads mapped: 87.39

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9620 c.2319G>A synonymous_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 0.98
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.14
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.15
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.19
rrl 1476164 n.2507A>C non_coding_transcript_exon_variant 0.19
rrl 1476165 n.2508T>C non_coding_transcript_exon_variant 0.19
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.15
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.15
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.15
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.15
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.15
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.15
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.14
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.14
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.14
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.15
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.17
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.17
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.19
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.22
rrl 1476252 n.2595T>A non_coding_transcript_exon_variant 0.21
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.22
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.23
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.17
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.18
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.18
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.23
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.18
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.18
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.18
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.2
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.21
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.21
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.38
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.38
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.35
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.38
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.41
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.41
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.39
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.37
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.34
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.4
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.43
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.38
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.37
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.34
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.32
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.32
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.31
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.31
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.31
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.32
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.32
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.32
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.32
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.33
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.31
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.23
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.21
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.21
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.18
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087605 c.786G>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408159 p.Arg15Pro missense_variant 1.0