TB-Profiler result

Run: ERR4798262
Summary

Run ID: ERR4798262

Sample name:

Date: 2024-10-04T17:46:46.911890

Number of reads: 1682370

Percentage reads mapped: 42.25

Median coverage: 58.0

Strain: La1.2.BCG

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.2
La1 M.bovis None 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Ala388Gly Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.654_657delTGAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.662_663insGCAA Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491434 c.654_657delTGAC frameshift_variant 0.71 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491444 c.662_663insGCAA frameshift_variant 0.71 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance Mutation from literature
katG 2155107 p.Ile335Thr missense_variant 0.59 isoniazid Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.8 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.46 ethambutol Uncertain significance Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.42 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 24 c.24C>A synonymous_variant 0.67 isoniazid
dnaA 30 c.30C>G synonymous_variant 0.64 isoniazid
dnaA 41 p.Asn14Ser missense_variant 0.6 isoniazid
dnaA 45 c.45G>A synonymous_variant 0.59 isoniazid
dnaA 624 c.624C>T synonymous_variant 0.75 isoniazid Not assoc w R - Interim
dnaA 633 c.633T>C synonymous_variant 0.77 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.77 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.81 isoniazid
dnaA 666 c.666C>A synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>A synonymous_variant 0.81 isoniazid
dnaA 678 c.678A>G synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 682 c.682T>C synonymous_variant 0.81 isoniazid
dnaA 687 c.687C>T synonymous_variant 0.81 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.79 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.81 isoniazid
dnaA 702 c.702C>G synonymous_variant 0.81 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.76 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.76 isoniazid
dnaA 711 c.711C>G synonymous_variant 0.77 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.85 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.86 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.85 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.84 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.81 isoniazid
dnaA 810 c.810C>G synonymous_variant 0.82 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.82 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.82 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.8 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.81 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.81 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.82 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.8 isoniazid
dnaA 876 c.876C>T synonymous_variant 0.82 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.82 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.83 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.82 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.8 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.81 isoniazid
dnaA 924 c.924C>G synonymous_variant 0.82 isoniazid
dnaA 955 c.955_957delAGAinsCGG synonymous_variant 0.81 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.78 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.78 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.76 isoniazid
dnaA 993 c.993A>G synonymous_variant 0.76 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1002 c.1002G>A synonymous_variant 0.76 isoniazid
dnaA 1014 c.1014C>G synonymous_variant 0.73 isoniazid
dnaA 1020 c.1020C>G synonymous_variant 0.64 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.64 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.63 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.59 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.54 isoniazid
dnaA 1041 c.1041G>A synonymous_variant 0.54 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.53 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.51 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.53 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.45 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.39 isoniazid
dnaA 1078 c.1078_1080delCTCinsTTG synonymous_variant 0.39 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.59 isoniazid
dnaA 1110 c.1110T>G synonymous_variant 0.53 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.54 isoniazid
dnaA 1116 c.1116C>G synonymous_variant 0.53 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.51 isoniazid
dnaA 1125 c.1125G>T synonymous_variant 0.49 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.53 isoniazid
dnaA 1137 c.1137C>T synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 1149 c.1149C>G synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 1152 c.1152A>G synonymous_variant 0.62 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.64 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.64 isoniazid
dnaA 1167 c.1167A>C synonymous_variant 0.65 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.66 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 0.66 isoniazid Not assoc w R - Interim
dnaA 1185 c.1185C>G synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 0.71 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.71 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.73 isoniazid
dnaA 1224 c.1224C>G synonymous_variant 0.75 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.79 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.78 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.76 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.72 isoniazid
dnaA 1291 c.1291_1293delCTTinsTTG synonymous_variant 0.71 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1314 c.1314A>G synonymous_variant 0.67 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.66 isoniazid
dnaA 1318 c.1318C>T synonymous_variant 0.66 isoniazid
dnaA 1323 c.1323C>G synonymous_variant 0.66 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.63 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.59 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>G synonymous_variant 0.52 isoniazid
dnaA 1380 c.1380C>G synonymous_variant 0.44 isoniazid Not assoc w R - Interim
dnaA 1383 c.1383A>G synonymous_variant 0.42 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.4 isoniazid Not assoc w R - Interim
gyrB 6086 p.Thr283Ala missense_variant 0.33 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6109 c.870G>A synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6112 p.Met291Ile missense_variant 0.65 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrB 6115 c.876A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.38 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6196 c.957C>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6199 c.960C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6235 c.996C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.82 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6251 c.1012C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6388 c.-914T>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>A upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 6594 p.Lys452Arg missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>T upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6674 c.-628_-626delCTTinsTTG upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6748 c.-554G>A upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.6 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6901 c.-401G>A upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>A upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7210 c.-92C>T upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7508 c.207C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7619 c.318C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7691 c.390C>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7697 c.396C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7781 c.480G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8348 c.1047C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8405 c.1104C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8525 c.1224C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8526 c.1225C>A synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8567 p.Ile422Met missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8726 c.1425G>A synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8744 p.Asp481Glu missense_variant 0.68 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8750 c.1449C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 0.56 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.56 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.66 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>A synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.79 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9008 c.1707C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.68 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.76 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9260 c.1959G>C synonymous_variant 0.73 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9261 c.1960_1962delCGCinsAGG synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9311 c.2010C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9326 c.2025G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>A synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.66 levofloxacin
moxifloxacin
Rv0010c 13298 p.Ile87Met missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13304 c.255G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
fgd1 490777 c.-6G>T upstream_gene_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.52 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490809 c.27A>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 490848 c.66A>G synonymous_variant 0.61 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490851 c.69A>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 490867 p.Ala29Ser missense_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 490902 c.120T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Glu missense_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 490929 c.147C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490959 c.177C>G synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 490980 p.Asn66Lys missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490984 p.Leu68Ile missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490987 p.Leu69Thr missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fgd1 491031 c.249C>G synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Asp missense_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491103 c.321C>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491130 c.348C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Asp missense_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.85 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491229 c.447C>T synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.85 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491296 p.Val172Ile missense_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491302 p.Ile174Val missense_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491310 c.528C>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491340 c.558C>A synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 0.78 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491364 c.582T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491379 c.597C>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491397 c.615G>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491409 c.627G>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491412 c.630G>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491415 c.633A>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491418 c.636A>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491421 c.639A>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491430 c.648T>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491453 p.Gly224Asp missense_variant 0.82 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fgd1 491455 p.Ile225Val missense_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491472 c.690A>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491583 c.801G>A synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491589 c.807G>A synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491652 c.870C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491661 c.879C>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491673 c.891A>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491676 c.894T>G synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491679 c.897A>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491685 c.903G>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491688 c.906A>G synonymous_variant 0.76 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491697 c.915G>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491709 c.927A>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491712 c.930T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 574559 c.-789T>G upstream_gene_variant 0.36 isoniazid
ethionamide
mshA 574565 c.-783T>G upstream_gene_variant 0.43 isoniazid
ethionamide
mshA 574586 c.-762G>C upstream_gene_variant 0.42 isoniazid
ethionamide
mshA 574589 c.-759T>C upstream_gene_variant 0.44 isoniazid
ethionamide
mshA 574592 c.-756C>G upstream_gene_variant 0.42 isoniazid
ethionamide
mshA 574595 c.-753A>G upstream_gene_variant 0.42 isoniazid
ethionamide
mshA 574604 c.-744C>G upstream_gene_variant 0.45 isoniazid
ethionamide
mshA 574605 c.-743G>C upstream_gene_variant 0.45 isoniazid
ethionamide
mshA 574616 c.-732G>C upstream_gene_variant 0.48 isoniazid
ethionamide
mshA 574631 c.-717C>G upstream_gene_variant 0.55 isoniazid
ethionamide
mshA 574640 c.-708G>C upstream_gene_variant 0.55 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574659 c.-689A>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574673 c.-675A>G upstream_gene_variant 0.61 isoniazid
ethionamide
mshA 574679 c.-669C>T upstream_gene_variant 0.62 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574683 c.-665T>C upstream_gene_variant 0.62 isoniazid Uncertain significance
ethionamide
mshA 574694 c.-654C>G upstream_gene_variant 0.63 isoniazid
ethionamide
mshA 574712 c.-636A>G upstream_gene_variant 0.6 isoniazid
ethionamide
mshA 574718 c.-630A>G upstream_gene_variant 0.6 isoniazid
ethionamide
mshA 574724 c.-624T>C upstream_gene_variant 0.55 isoniazid
ethionamide
mshA 574731 c.-617A>G upstream_gene_variant 0.59 isoniazid
ethionamide
mshA 574739 c.-609T>C upstream_gene_variant 0.61 isoniazid
ethionamide
mshA 574742 c.-606G>C upstream_gene_variant 0.61 isoniazid
ethionamide
mshA 574763 c.-585T>C upstream_gene_variant 0.59 isoniazid Uncertain significance
ethionamide
mshA 574766 c.-582T>C upstream_gene_variant 0.59 isoniazid Uncertain significance
ethionamide
mshA 574769 c.-579C>G upstream_gene_variant 0.59 isoniazid
ethionamide
mshA 574781 c.-567G>C upstream_gene_variant 0.54 isoniazid
ethionamide
mshA 574782 c.-566_-564delCCCinsGCG upstream_gene_variant 0.54 isoniazid
ethionamide
mshA 574799 c.-549T>C upstream_gene_variant 0.36 isoniazid
ethionamide
mshA 574802 c.-546A>G upstream_gene_variant 0.33 isoniazid
ethionamide
mshA 574803 c.-545A>C upstream_gene_variant 0.33 isoniazid
ethionamide
mshA 574814 c.-534T>C upstream_gene_variant 0.32 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.42 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 0.55 isoniazid
ethionamide
mshA 575593 c.246G>C synonymous_variant 0.56 isoniazid
ethionamide
mshA 575629 c.282A>G synonymous_variant 0.58 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
ethionamide
mshA 575641 c.294A>G synonymous_variant 0.51 isoniazid
ethionamide
mshA 575647 c.300G>C synonymous_variant 0.45 isoniazid
ethionamide
mshA 575649 p.Val101Ala missense_variant 0.44 isoniazid
ethionamide
mshA 575653 c.306G>C synonymous_variant 0.43 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.44 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.43 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 0.44 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575674 c.327G>C synonymous_variant 0.52 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.56 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.53 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.53 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.57 isoniazid
ethionamide
mshA 575725 c.378C>G synonymous_variant 0.56 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.59 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.56 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.58 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.58 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.6 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.6 isoniazid
ethionamide
mshA 575786 p.Tyr147His missense_variant 0.6 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 0.6 isoniazid Not assoc w R - Interim
ethionamide
mshA 575806 c.459G>C synonymous_variant 0.6 isoniazid
ethionamide
mshA 575824 c.477T>A synonymous_variant 0.62 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.67 isoniazid
ethionamide
mshA 575845 c.498C>T synonymous_variant 0.66 isoniazid Not assoc w R - Interim
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.67 isoniazid
ethionamide
mshA 575875 c.528C>G synonymous_variant 0.62 isoniazid
ethionamide
mshA 575878 c.531A>C synonymous_variant 0.62 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.57 isoniazid
ethionamide
mshA 575899 c.552G>A synonymous_variant 0.56 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.5 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 0.47 isoniazid
ethionamide
mshA 575924 p.Gly193Ser missense_variant 0.47 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.45 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.44 isoniazid
ethionamide
mshA 575953 c.606G>C synonymous_variant 0.44 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.39 isoniazid
ethionamide
mshA 575984 c.637T>C synonymous_variant 0.34 isoniazid
ethionamide
ccsA 619506 c.-385A>T upstream_gene_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 619570 c.-321G>C upstream_gene_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 619573 c.-318G>C upstream_gene_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 619588 c.-303C>G upstream_gene_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620208 c.318G>C synonymous_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620226 c.336G>A synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620246 p.Leu119Cys missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620253 c.363G>C synonymous_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Leu missense_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620271 c.381C>G synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620275 c.385C>T synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620290 p.Tyr134His missense_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
ccsA 620295 c.405G>C synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620296 p.Pro136Ala missense_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>A synonymous_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 620316 c.426G>C synonymous_variant 0.6 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620340 c.450C>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620343 c.453G>C synonymous_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.36 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620430 c.540C>T synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 0.38 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620442 c.552G>C synonymous_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620449 p.Leu187Met missense_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620454 c.564C>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>C synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620559 c.669A>G synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620569 p.Gly227Arg missense_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620583 c.693G>C synonymous_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620597 p.Ala236Gly missense_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>G synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>T synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620682 c.792G>A synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620691 c.801G>T synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 620712 c.822G>A synonymous_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.78 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620758 c.868_870delCGCinsAGG synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620766 c.876C>G synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620769 c.879C>G synonymous_variant 0.7 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620781 c.891C>G synonymous_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>T synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620793 c.903G>C synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620808 c.918T>C synonymous_variant 0.68 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620829 c.939G>C synonymous_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620832 c.942C>T synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620844 c.954C>T synonymous_variant 0.49 kanamycin
capreomycin
amikacin
ccsA 620856 c.966C>T synonymous_variant 0.33 kanamycin
capreomycin
amikacin
Rv0565c 656184 c.1287G>C synonymous_variant 0.38 ethionamide
Rv0565c 656189 p.Glu428Gln missense_variant 0.38 ethionamide
Rv0565c 656196 c.1275G>C synonymous_variant 0.38 ethionamide
Rv0565c 656206 p.Ala422Tyr missense_variant 0.41 ethionamide
Rv0565c 656212 p.Arg420His missense_variant 0.45 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 0.46 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 0.48 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 0.5 ethionamide Not assoc w R - Interim
Rv0565c 656228 p.Ala415Ser missense_variant 0.5 ethionamide
Rv0565c 656238 c.1233A>G synonymous_variant 0.55 ethionamide
Rv0565c 656244 c.1227A>G synonymous_variant 0.53 ethionamide
Rv0565c 656247 c.1224A>G synonymous_variant 0.52 ethionamide
Rv0565c 656256 c.1215G>C synonymous_variant 0.53 ethionamide
Rv0565c 656262 c.1209C>G synonymous_variant 0.55 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.55 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.55 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.57 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.55 ethionamide
Rv0565c 656292 c.1179G>C synonymous_variant 0.55 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.53 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.49 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.29 ethionamide
Rv0565c 656424 c.1047G>A synonymous_variant 0.28 ethionamide
Rv0565c 656436 c.1035C>G synonymous_variant 0.29 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 0.28 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.3 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.31 ethionamide
Rv0565c 656467 p.Gly335Ala missense_variant 0.31 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.27 ethionamide Not assoc w R - Interim
Rv0565c 656523 c.948G>C synonymous_variant 0.32 ethionamide Not assoc w R - Interim
Rv0565c 657563 c.-93T>C upstream_gene_variant 0.48 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.62 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.67 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.74 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 0.73 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.76 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.81 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.86 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.91 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.91 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.88 ethionamide
hadA 731711 c.-219T>C upstream_gene_variant 0.45 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.65 isoniazid
hadA 731748 c.-182T>C upstream_gene_variant 0.65 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.67 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.69 isoniazid
hadA 731774 c.-156T>G upstream_gene_variant 0.63 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.68 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.65 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.65 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 0.64 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.55 isoniazid
hadA 731859 c.-71G>C upstream_gene_variant 0.5 isoniazid
hadA 731934 p.Ala2Gly missense_variant 0.61 isoniazid
hadA 731939 c.10_11delAGinsTC synonymous_variant 0.58 isoniazid
hadA 731942 p.Ala5Thr missense_variant 0.58 isoniazid
hadA 731953 c.24T>C synonymous_variant 0.65 isoniazid
hadA 731962 c.33T>C synonymous_variant 0.63 isoniazid
hadA 731965 c.36C>T synonymous_variant 0.65 isoniazid
hadA 731995 c.66G>C synonymous_variant 0.72 isoniazid
hadA 732004 c.75T>C synonymous_variant 0.72 isoniazid
hadA 732010 c.81G>A synonymous_variant 0.72 isoniazid Not assoc w R - Interim
hadA 732016 c.87C>G synonymous_variant 0.72 isoniazid Not assoc w R - Interim
hadA 732019 c.90C>G synonymous_variant 0.7 isoniazid
hadA 732025 c.96T>G synonymous_variant 0.7 isoniazid
hadA 732028 c.99A>G synonymous_variant 0.71 isoniazid
hadA 732032 p.Asp35Thr missense_variant 0.72 isoniazid
hadA 732040 c.111G>C synonymous_variant 0.72 isoniazid
hadA 732045 p.Tyr39Phe missense_variant 0.71 isoniazid
hadA 732060 p.Gly44Ala missense_variant 0.67 isoniazid
hadA 732070 c.141A>G synonymous_variant 0.66 isoniazid
hadA 732073 c.144C>G synonymous_variant 0.61 isoniazid
hadA 732076 c.147G>T synonymous_variant 0.61 isoniazid
hadA 732079 c.150T>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
hadA 732086 c.157T>C synonymous_variant 0.66 isoniazid Not assoc w R - Interim
hadA 732089 c.160C>T synonymous_variant 0.64 isoniazid
hadA 732094 c.165T>G synonymous_variant 0.68 isoniazid
hadA 732098 c.169T>C synonymous_variant 0.67 isoniazid
hadA 732106 c.177T>C synonymous_variant 0.66 isoniazid
hadA 732125 p.Lys66Gln missense_variant 0.65 isoniazid
hadA 732130 c.201C>G synonymous_variant 0.65 isoniazid
hadA 732133 c.204G>A synonymous_variant 0.67 isoniazid Not assoc w R - Interim
hadA 732134 p.Ala69Ser missense_variant 0.67 isoniazid
hadA 732151 c.222T>C synonymous_variant 0.68 isoniazid
hadA 732157 p.Asn76Lys missense_variant 0.68 isoniazid
hadA 732163 c.234G>C synonymous_variant 0.66 isoniazid
hadA 732164 p.Thr79Val missense_variant 0.66 isoniazid
hadA 732168 p.Ala80Glu missense_variant 0.68 isoniazid
hadA 732172 p.Glu81Asp missense_variant 0.68 isoniazid
hadA 732190 c.261A>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
hadA 732193 c.264C>T synonymous_variant 0.68 isoniazid
hadA 732196 c.267A>G synonymous_variant 0.68 isoniazid
hadA 732204 p.Lys92Arg missense_variant 0.71 isoniazid
hadA 732209 p.Glu94Arg missense_variant 0.7 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.7 isoniazid Not assoc w R - Interim
hadA 732238 c.309G>C synonymous_variant 0.69 isoniazid
hadA 732241 c.312C>T synonymous_variant 0.69 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.66 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.67 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.69 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.64 isoniazid
hadA 732272 p.Ala115Thr missense_variant 0.63 isoniazid Uncertain significance
hadA 732278 p.Gly117Gln missense_variant 0.61 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.62 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.61 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.58 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.54 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.72 isoniazid
hadA 732367 c.438C>G synonymous_variant 0.7 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.71 isoniazid
hadA 732373 c.444G>A synonymous_variant 0.71 isoniazid
hadA 732382 c.453delGinsAAAA conservative_inframe_insertion&synonymous_variant 0.7 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.74 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.72 isoniazid
nusG 734111 c.-143A>G upstream_gene_variant 0.33 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.39 rifampicin
nusG 734116 c.-138T>C upstream_gene_variant 0.58 rifampicin Not assoc w R
nusG 734120 c.-134T>C upstream_gene_variant 0.5 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.61 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.64 rifampicin
nusG 734170 c.-83_-81delCGC upstream_gene_variant 0.61 rifampicin
nusG 734177 c.-77_-76insCTG upstream_gene_variant 0.6 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.61 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 0.6 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.6 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.59 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.59 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 0.59 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 0.59 rifampicin
nusG 734227 c.-27C>T upstream_gene_variant 0.59 rifampicin
nusG 734239 c.-15A>G upstream_gene_variant 0.57 rifampicin Uncertain significance
nusG 734240 c.-14G>A upstream_gene_variant 0.57 rifampicin
nusG 734246 c.-8T>C upstream_gene_variant 0.57 rifampicin
nusG 734261 p.Thr3Ser missense_variant 0.58 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.32 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.34 rifampicin
nusG 734418 c.165C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734424 c.171G>A synonymous_variant 0.34 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.48 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.6 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.68 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.73 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.64 rifampicin
nusG 734596 c.343_345delTTGinsCTC synonymous_variant 0.58 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.54 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.36 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.39 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.37 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.37 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.37 rifampicin
nusG 734718 c.465G>C synonymous_variant 0.37 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.37 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.37 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.4 rifampicin
nusG 734731 p.Ala160Thr missense_variant 0.45 rifampicin
nusG 734742 c.489T>C synonymous_variant 0.57 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.54 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.54 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.54 rifampicin
nusG 734778 c.525G>C synonymous_variant 0.58 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.6 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.6 rifampicin
nusG 734787 c.534T>C synonymous_variant 0.6 rifampicin
nusG 734814 c.561G>C synonymous_variant 0.64 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.62 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.57 rifampicin
nusG 734841 c.588G>A synonymous_variant 0.51 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.49 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.49 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.5 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.35 rifampicin
mmaA3 737703 c.447T>C synonymous_variant 0.27 isoniazid
mmaA3 737715 p.Ile145Leu missense_variant 0.34 isoniazid
mmaA3 737721 c.429A>G synonymous_variant 0.38 isoniazid
mmaA3 737728 p.Thr141Ile missense_variant 0.41 isoniazid
mmaA3 737730 c.420A>C synonymous_variant 0.4 isoniazid
mmaA3 737748 c.402G>A synonymous_variant 0.54 isoniazid
mmaA3 737753 p.Ser133Gly missense_variant 0.5 isoniazid
mmaA3 737757 p.Asn131Glu missense_variant 0.49 isoniazid
mmaA3 737760 c.390C>G synonymous_variant 0.49 isoniazid
mmaA3 737777 c.373C>T synonymous_variant 0.57 isoniazid
mmaA3 737785 p.His122Arg missense_variant 0.57 isoniazid
mmaA3 737787 c.363G>C synonymous_variant 0.57 isoniazid
mmaA3 737790 c.360C>G synonymous_variant 0.57 isoniazid
mmaA3 737794 p.Asn119Ala missense_variant 0.57 isoniazid
mmaA3 737797 p.Thr118Ser missense_variant 0.56 isoniazid
mmaA3 737804 p.Val116Ile missense_variant 0.56 isoniazid
mmaA3 737807 p.Lys115Gln missense_variant 0.58 isoniazid
mmaA3 737817 p.Gln111Glu missense_variant 0.62 isoniazid
mmaA3 737821 p.Gln110Arg missense_variant 0.64 isoniazid
mmaA3 737841 p.Lys103Arg missense_variant 0.67 isoniazid
mmaA3 737855 c.295T>C synonymous_variant 0.71 isoniazid
mmaA3 737889 c.261T>C synonymous_variant 0.73 isoniazid
mmaA3 737904 c.246T>G synonymous_variant 0.74 isoniazid
mmaA3 737916 c.234C>T synonymous_variant 0.68 isoniazid
mmaA3 737919 p.Val77Ile missense_variant 0.67 isoniazid
mmaA3 737931 c.219A>C synonymous_variant 0.61 isoniazid
mmaA3 737937 c.213A>G synonymous_variant 0.61 isoniazid
mmaA3 737943 c.207A>G synonymous_variant 0.64 isoniazid
mmaA3 737946 c.204A>C synonymous_variant 0.64 isoniazid
mmaA3 737949 c.201G>C synonymous_variant 0.63 isoniazid
mmaA3 737959 p.Gly64Asp missense_variant 0.63 isoniazid
mmaA3 737964 c.186C>G synonymous_variant 0.57 isoniazid
mmaA3 737967 c.183A>G synonymous_variant 0.57 isoniazid
mmaA3 737973 p.Leu59Ile missense_variant 0.52 isoniazid
mmaA3 737984 p.Val56Leu missense_variant 0.46 isoniazid
mmaA3 737988 c.162A>G synonymous_variant 0.45 isoniazid
mmaA3 737991 c.159A>G synonymous_variant 0.45 isoniazid
mmaA3 737999 c.151T>C synonymous_variant 0.42 isoniazid
mmaA3 738007 p.Asp48Gly missense_variant 0.32 isoniazid
rpoB 759546 c.-261A>G upstream_gene_variant 1.0 rifampicin Not assoc w R
rpoB 760046 c.240G>C synonymous_variant 0.32 rifampicin
rpoB 760067 c.261G>T synonymous_variant 0.49 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.54 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>G synonymous_variant 0.78 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.74 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.78 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.79 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.81 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.8 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.82 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.82 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.81 rifampicin
rpoB 760343 c.537G>C synonymous_variant 0.8 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.8 rifampicin Uncertain significance
rpoB 760381 p.Thr192Ile missense_variant 0.79 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.77 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.71 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760490 c.684C>T synonymous_variant 0.24 rifampicin Not assoc w R
rpoB 760511 c.705G>C synonymous_variant 0.77 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.77 rifampicin Uncertain significance
rpoB 760528 p.Gln241Arg missense_variant 0.74 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.75 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.78 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.82 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.79 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>A synonymous_variant 0.69 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760716 c.910_912delCGCinsAGG synonymous_variant 0.41 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 0.48 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.58 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.71 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.71 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 0.86 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.81 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.81 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.82 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 0.83 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.81 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 0.82 rifampicin
rpoB 761186 c.1380G>A synonymous_variant 0.82 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.82 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 0.84 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.86 rifampicin
rpoB 761348 c.1542C>G synonymous_variant 0.86 rifampicin
rpoB 761354 c.1548C>G synonymous_variant 0.86 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 0.86 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.85 rifampicin
rpoB 761390 c.1584C>T synonymous_variant 0.9 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.88 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.88 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.88 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.88 rifampicin
rpoB 761457 p.Pro551Lys missense_variant 0.89 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.84 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 0.84 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.83 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.82 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.83 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.82 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.7 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.71 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.7 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.67 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.66 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.61 rifampicin
rpoB 761723 p.GluGlu639AspLys missense_variant 0.57 rifampicin
rpoB 761726 c.1920A>G synonymous_variant 0.49 rifampicin
rpoB 761727 c.1921_1922delAGinsTC synonymous_variant 0.49 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.62 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.65 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.65 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.68 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.69 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.69 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.68 rifampicin
rpoB 761807 c.2001C>T synonymous_variant 0.65 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.6 rifampicin
rpoB 761831 c.2025C>A synonymous_variant 0.58 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.61 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.62 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.63 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.68 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.7 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.73 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.68 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.65 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.68 rifampicin
rpoB 761913 p.Asp703Gln missense_variant 0.67 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.68 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.72 rifampicin
rpoB 761924 c.2118G>A synonymous_variant 0.73 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.83 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.88 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.88 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.86 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.86 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>G synonymous_variant 0.87 rifampicin
rpoB 762167 c.2361T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.86 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 0.83 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.82 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.8 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.78 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.78 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.8 rifampicin
rpoB 762353 c.2547C>T synonymous_variant 0.8 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.79 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.81 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.82 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.8 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.8 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.78 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.76 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.75 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.82 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.85 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.85 rifampicin
rpoB 762491 c.2685T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762510 p.Ala902Pro missense_variant 0.78 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.78 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.77 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.77 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.77 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.82 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.74 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.75 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 0.69 rifampicin
rpoB 762599 c.2793T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 762605 c.-765T>C upstream_gene_variant 0.7 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 0.71 rifampicin
rpoB 762630 p.Ala942Thr missense_variant 0.61 rifampicin Uncertain significance
rpoB 762633 p.Ala943Ser missense_variant 0.61 rifampicin
rpoC 762641 c.-729G>C upstream_gene_variant 0.53 rifampicin
rpoB 762725 c.2919C>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 762728 c.-642C>G upstream_gene_variant 0.71 rifampicin
rpoB 762749 c.2943C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762759 p.Cys985Ala missense_variant 0.72 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.72 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762794 c.-576C>G upstream_gene_variant 0.76 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.77 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.78 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762957 c.3151C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762980 c.-390T>C upstream_gene_variant 0.91 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.88 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.89 rifampicin
rpoC 763136 c.-234C>G upstream_gene_variant 0.88 rifampicin
rpoC 763157 c.-213G>C upstream_gene_variant 0.89 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.86 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.83 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.83 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>C upstream_gene_variant 0.79 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.79 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.76 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763247 c.-123G>A upstream_gene_variant 0.74 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.72 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.79 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.86 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.86 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.83 rifampicin
rpoC 763654 c.285C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763714 c.345G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.86 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.87 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.88 rifampicin
rpoC 763768 c.399C>G synonymous_variant 0.88 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.91 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.91 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.91 rifampicin
rpoC 763836 p.Ala156Val missense_variant 0.89 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.89 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.91 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.89 rifampicin
rpoC 763876 c.507A>G synonymous_variant 0.88 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.88 rifampicin
rpoC 763885 c.516C>G synonymous_variant 0.87 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.87 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.87 rifampicin
rpoC 763912 c.543G>C synonymous_variant 0.86 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763939 c.570G>A synonymous_variant 0.86 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763963 c.594C>G synonymous_variant 0.87 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.87 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.84 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.85 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.84 rifampicin
rpoC 764023 c.654G>C synonymous_variant 0.86 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.86 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.86 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.85 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.86 rifampicin
rpoC 764080 c.711C>T synonymous_variant 0.85 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.85 rifampicin
rpoC 764095 c.726C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.86 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.85 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.82 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.82 rifampicin
rpoC 764209 c.840C>G synonymous_variant 0.82 rifampicin
rpoC 764215 c.846A>G synonymous_variant 0.82 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.83 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.84 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.83 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.85 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.84 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.85 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.86 rifampicin
rpoC 764290 c.921C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764329 c.960C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>G synonymous_variant 0.83 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.78 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.78 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764479 c.1110G>A synonymous_variant 0.83 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.84 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>G synonymous_variant 0.82 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.87 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.89 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.89 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.86 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.83 rifampicin
rpoC 764650 c.1281G>C synonymous_variant 0.82 rifampicin
rpoC 764713 c.1344G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.81 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.83 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.85 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 0.83 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.8 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.75 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639_1641delTTGinsCTC synonymous_variant 0.48 rifampicin
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.49 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.49 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>T synonymous_variant 0.49 rifampicin
rpoC 765034 c.1665T>G synonymous_variant 0.49 rifampicin
rpoC 765037 c.1668C>G synonymous_variant 0.49 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.49 rifampicin
rpoC 765076 c.1707A>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>C synonymous_variant 0.51 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.55 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765171 p.Pro601Leu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765292 c.1923G>T synonymous_variant 0.59 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.59 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.6 rifampicin Uncertain significance
rpoC 765313 c.1944C>T synonymous_variant 0.58 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Val missense_variant 0.54 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.55 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765403 c.2034G>C synonymous_variant 0.68 rifampicin
rpoC 765404 p.Leu679Val missense_variant 0.69 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.68 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.69 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.77 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.82 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 0.82 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.82 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.84 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.83 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.83 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.89 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.87 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.87 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.88 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.86 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.88 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.88 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.87 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.88 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.87 rifampicin
rpoC 765928 c.2559C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.87 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.85 rifampicin
rpoC 766003 c.2634G>C synonymous_variant 0.85 rifampicin
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.86 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.86 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.87 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.86 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.84 rifampicin
rpoC 766066 c.2697C>G synonymous_variant 0.8 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.79 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.79 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.76 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>G synonymous_variant 0.8 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.79 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.77 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766193 p.Gln942Glu missense_variant 0.77 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.82 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766222 c.2853T>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.8 rifampicin
rpoC 766231 c.2862T>G synonymous_variant 0.81 rifampicin
rpoC 766234 c.2865T>G synonymous_variant 0.81 rifampicin
rpoC 766237 c.2868T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 0.8 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.8 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.81 rifampicin
rpoC 766285 c.2916C>G synonymous_variant 0.83 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.83 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.81 rifampicin
rpoC 766312 c.2943T>A synonymous_variant 0.78 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.78 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766366 c.2997C>G synonymous_variant 0.77 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 0.76 rifampicin
rpoC 766378 c.3009C>T synonymous_variant 0.75 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.76 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.74 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.76 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.78 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.78 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.76 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.74 rifampicin
rpoC 766462 c.3093G>T synonymous_variant 0.75 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 0.74 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.75 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.76 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.78 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.8 rifampicin
rpoC 766526 p.Val1053Ile missense_variant 0.8 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.8 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.82 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.82 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 0.82 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.82 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.86 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.83 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.82 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.86 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.91 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.95 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 0.96 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.96 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.96 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.91 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.91 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.91 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.91 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.91 rifampicin
rpoC 766686 p.Glu1106Val missense_variant 0.91 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.88 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.84 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.86 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.88 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.85 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.85 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.84 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.84 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.87 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.92 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 0.9 rifampicin
rpoC 766996 c.3627C>G synonymous_variant 0.9 rifampicin
rpoC 767020 c.3651C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 0.84 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.81 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.81 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 0.82 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 767242 p.Gln1291His missense_variant 0.71 rifampicin
rpoC 767263 c.3894T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.55 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.46 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.45 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.46 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775847 c.2634G>C synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775851 p.Ser877Thr missense_variant 0.36 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775864 p.Ala873Ser missense_variant 0.35 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 775870 p.Ile871Val missense_variant 0.36 bedaquiline
clofazimine
mmpL5 775874 c.2607C>G synonymous_variant 0.31 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Met missense_variant 0.31 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.38 bedaquiline
clofazimine
mmpL5 775913 c.2568C>G synonymous_variant 0.4 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 0.4 bedaquiline
clofazimine
mmpL5 775919 c.2562G>C synonymous_variant 0.38 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 0.47 bedaquiline
clofazimine
mmpL5 775949 c.2532G>C synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.38 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.36 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 776027 c.2454G>T synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 776039 c.2442C>G synonymous_variant 0.37 bedaquiline
clofazimine
mmpL5 776042 c.2439C>G synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.32 bedaquiline
clofazimine
mmpL5 776057 c.2424G>C synonymous_variant 0.32 bedaquiline
clofazimine
mmpL5 776066 c.2415C>G synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776129 c.2352C>G synonymous_variant 0.34 bedaquiline
clofazimine
mmpL5 776132 p.Ala783Ser missense_variant 0.33 bedaquiline
clofazimine
mmpL5 776137 p.Ser782Ala missense_variant 0.31 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776395 p.Phe696Leu missense_variant 1.0 bedaquiline Uncertain significance
clofazimine Not assoc w R
rpsL 781134 c.-426T>C upstream_gene_variant 0.43 streptomycin
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.52 streptomycin
rpsL 781592 c.33T>C synonymous_variant 0.59 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.66 streptomycin
rpsL 781634 c.75G>A synonymous_variant 0.78 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.78 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.77 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.8 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.84 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.83 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.84 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.84 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.83 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.83 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.84 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.83 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.83 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.82 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.81 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.82 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.83 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.82 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.83 streptomycin Not assoc w R - Interim
rpsL 781838 c.279G>C synonymous_variant 0.83 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.84 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.83 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.83 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.83 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.81 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.79 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.78 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.76 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.76 streptomycin Uncertain significance
rplC 800357 c.-452C>A upstream_gene_variant 1.0 linezolid Not assoc w R
rplC 800516 c.-293G>C upstream_gene_variant 0.44 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.5 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.53 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.62 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.58 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.62 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.63 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.62 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.63 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.72 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.73 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.71 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.67 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.65 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.6 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.56 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.54 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.52 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.52 linezolid
rplC 800904 c.96G>C synonymous_variant 0.27 linezolid
rplC 800916 c.108A>G synonymous_variant 0.33 linezolid
rplC 800931 c.123G>A synonymous_variant 0.33 linezolid
rplC 800937 c.129A>G synonymous_variant 0.38 linezolid
rplC 800946 c.138T>C synonymous_variant 0.38 linezolid
rplC 800949 c.141T>C synonymous_variant 0.36 linezolid
rplC 800958 c.150G>C synonymous_variant 0.38 linezolid
rplC 800970 c.162T>C synonymous_variant 0.38 linezolid Not assoc w R - Interim
rplC 800985 c.177A>G synonymous_variant 0.38 linezolid
rplC 800988 c.180C>T synonymous_variant 0.39 linezolid
rplC 801004 p.Leu66Val missense_variant 0.51 linezolid
rplC 801009 c.201A>C synonymous_variant 0.5 linezolid
rplC 801027 c.219C>G synonymous_variant 0.52 linezolid
rplC 801039 c.231A>G synonymous_variant 0.52 linezolid
rplC 801045 c.237A>G synonymous_variant 0.53 linezolid
rplC 801063 c.255G>C synonymous_variant 0.54 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.52 linezolid
rplC 801078 c.270T>C synonymous_variant 0.45 linezolid
rplC 801084 c.276G>C synonymous_variant 0.45 linezolid
rplC 801085 p.Thr93Ala missense_variant 0.44 linezolid Uncertain significance
rplC 801090 c.282G>A synonymous_variant 0.44 linezolid
rplC 801094 p.Gln96Glu missense_variant 0.44 linezolid
rplC 801099 c.291T>C synonymous_variant 0.5 linezolid
rplC 801102 c.294G>C synonymous_variant 0.5 linezolid
rplC 801105 c.297A>G synonymous_variant 0.52 linezolid
rplC 801109 c.301T>C synonymous_variant 0.54 linezolid Not assoc w R - Interim
rplC 801117 c.309G>C synonymous_variant 0.56 linezolid
rplC 801132 c.324T>C synonymous_variant 0.55 linezolid
rplC 801137 p.Ser110Thr missense_variant 0.57 linezolid
rplC 801147 c.339T>C synonymous_variant 0.41 linezolid
rplC 801153 c.345G>C synonymous_variant 0.41 linezolid
rplC 801156 c.348T>C synonymous_variant 0.41 linezolid
rplC 801165 c.357G>A synonymous_variant 0.45 linezolid Not assoc w R - Interim
rplC 801171 c.363A>G synonymous_variant 0.48 linezolid
rplC 801174 c.366T>C synonymous_variant 0.45 linezolid
rplC 801183 c.375C>A synonymous_variant 0.57 linezolid
rplC 801195 c.387G>C synonymous_variant 0.65 linezolid
rplC 801204 c.396C>T synonymous_variant 0.57 linezolid
rplC 801222 c.414T>C synonymous_variant 0.65 linezolid
rplC 801228 c.420T>C synonymous_variant 0.65 linezolid
rplC 801231 c.423C>G synonymous_variant 0.64 linezolid
rplC 801247 c.439_441delCGTinsAGG synonymous_variant 0.68 linezolid
rplC 801255 c.447C>T synonymous_variant 0.7 linezolid
rplC 801267 c.459A>C synonymous_variant 0.69 linezolid
rplC 801270 c.462T>C synonymous_variant 0.68 linezolid
rplC 801276 c.468G>C synonymous_variant 0.69 linezolid
rplC 801285 c.477G>T synonymous_variant 0.7 linezolid
rplC 801288 c.480G>C synonymous_variant 0.71 linezolid
rplC 801312 c.504G>C synonymous_variant 0.73 linezolid
rplC 801324 c.516T>C synonymous_variant 0.74 linezolid
rplC 801339 c.531T>G synonymous_variant 0.7 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.7 linezolid
rplC 801348 c.540T>G synonymous_variant 0.71 linezolid
rplC 801357 c.549T>C synonymous_variant 0.72 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.71 linezolid
rplC 801396 c.588T>C synonymous_variant 0.64 linezolid
rplC 801402 c.594T>C synonymous_variant 0.6 linezolid
rplC 801405 c.597T>C synonymous_variant 0.61 linezolid
rplC 801408 c.600C>G synonymous_variant 0.61 linezolid
rplC 801420 c.612A>C synonymous_variant 0.56 linezolid
rplC 801423 c.615G>C synonymous_variant 0.53 linezolid
rplC 801426 c.618C>G synonymous_variant 0.55 linezolid
rplC 801438 c.630T>C synonymous_variant 0.62 linezolid
rplC 801442 p.Ile212Val missense_variant 0.65 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1303051 p.Val41Met missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1303425 c.495G>A synonymous_variant 0.29 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303431 c.501T>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1303437 c.507C>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303446 c.516C>A synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1303449 c.519C>T synonymous_variant 0.41 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303452 c.522G>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303455 c.525C>G synonymous_variant 0.54 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303476 c.546G>C synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303480 p.Gln184Glu missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>G synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>T synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303646 p.Ala239Val missense_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303665 c.735G>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303677 c.747C>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303761 c.831T>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303869 c.939T>C synonymous_variant 0.69 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303878 c.948G>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1303890 c.960G>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1303908 c.978C>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1303956 c.1026A>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303971 c.1041T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303973 p.Gly348Ala missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1304040 c.1110C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304050 c.1120T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304104 c.1174C>T synonymous_variant 0.58 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304112 c.1182G>A synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304115 c.1185A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1304133 c.1203G>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1304139 c.1209G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>A synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304465 p.Gly512Ala missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304472 c.1542T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304475 c.1545G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304481 c.1551T>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304484 c.1554C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304490 c.1560C>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1304502 c.1572G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304520 c.1590A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304601 c.1671C>T synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304604 c.1674C>T synonymous_variant 0.74 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304613 c.1683T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>A synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1304637 c.1707G>A synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Glu missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304682 c.1752C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304711 p.Ala594Glu missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304718 c.1788C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.58 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>A synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304802 c.1872G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 0.73 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304891 p.Ile654Thr missense_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304901 c.1971C>G synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.85 pretomanid
delamanid
clofazimine
fbiC 1304934 c.2004C>G synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.85 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1305006 p.Glu692Asp missense_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1305066 c.2136T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1305069 c.2139G>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1305075 c.2145T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1305090 c.2160C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305092 p.Ala721Gly missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1305112 p.Asp728Gln missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.52 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305129 c.2199C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305135 c.2205C>T synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1305174 c.2244T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305177 c.2247A>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305181 c.2251_2253delTTGinsCTT synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>A synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305219 c.2289T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1305234 c.2304G>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305237 c.2307A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305240 c.2310T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305243 c.2313T>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305244 c.2314T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305252 c.2322G>A synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1305276 c.2346G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305300 c.2370A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1305303 c.2373T>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305309 c.2379G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305310 p.Arg794Glu missense_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305318 c.2388C>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305320 p.Gln797Arg missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
sigE 1364790 c.378T>C synonymous_variant 0.54 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 0.57 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.58 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.6 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.61 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.59 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.55 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.53 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.54 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.56 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.56 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.56 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.62 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.61 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.65 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.53 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.55 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.55 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.55 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.59 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.59 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.56 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.69 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.69 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.66 pyrazinamide
sigE 1365036 c.624T>G synonymous_variant 0.58 pyrazinamide
sigE 1365037 c.625C>T synonymous_variant 0.55 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.56 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.48 pyrazinamide
embR 1417019 p.Cys110Tyr missense_variant 1.0 ethambutol Not assoc w R
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol
embR 1417793 c.-446C>T upstream_gene_variant 1.0 ethambutol
atpE 1460804 c.-241T>C upstream_gene_variant 0.68 bedaquiline
atpE 1460807 c.-238C>T upstream_gene_variant 0.67 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 0.66 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.62 bedaquiline
atpE 1460837 c.-208C>G upstream_gene_variant 0.61 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.6 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.51 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.49 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.5 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.46 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 0.61 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.65 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.68 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.69 bedaquiline
atpE 1461113 c.69C>A synonymous_variant 0.7 bedaquiline
atpE 1461125 c.81T>C synonymous_variant 0.71 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.71 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.68 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.68 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.69 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.67 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.68 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.68 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.64 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.64 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.61 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.53 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.52 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.45 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.4 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 0.38 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.83 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.77 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445delCinsTT non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrl 1473667 n.10T>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1473684 n.27G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474007 n.350A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474029 n.372G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474111 n.454T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474289 n.632C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474292 n.635T>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474409 n.756_776delACCCACACGCGCATACGCGCG non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474414 n.758_783delCNNNNNNNNNNNNNNNNNNNNNNNNN non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474435 n.778G>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474437 n.782_784delATA non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474714 n.1058dupT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474950 n.1293_1300delGCACATCCinsACA non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474964 n.1307_1315delTGGTGGGTGinsAGGT non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475245 n.1588T>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
inhA 1673490 c.-712A>G upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673499 c.-703T>G upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673502 c.-700C>G upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673505 c.-697A>T upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673523 c.-679G>T upstream_gene_variant 0.55 isoniazid
ethionamide
inhA 1673535 c.-667A>G upstream_gene_variant 0.59 isoniazid
ethionamide
inhA 1673536 c.-666C>A upstream_gene_variant 0.6 isoniazid
ethionamide
inhA 1673541 c.-661G>A upstream_gene_variant 0.66 isoniazid Uncertain significance
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673574 c.-628C>G upstream_gene_variant 0.79 isoniazid
ethionamide
inhA 1673580 c.-622T>C upstream_gene_variant 0.75 isoniazid Uncertain significance
ethionamide
inhA 1673583 c.-619A>G upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673589 c.-613A>G upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673595 c.-607A>C upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1673596 c.-606_-604delAAGinsGAC upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 0.64 isoniazid
ethionamide
inhA 1673616 c.-586A>G upstream_gene_variant 0.63 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 0.63 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 0.68 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 0.59 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673662 c.-540_-538delGTAinsATC upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.55 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 0.63 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673709 c.-493C>A upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsGTC upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673713 c.-489T>G upstream_gene_variant 0.5 isoniazid Uncertain significance
ethionamide
inhA 1673718 c.-484G>C upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 0.49 isoniazid
ethionamide
inhA 1673727 c.-475C>T upstream_gene_variant 0.52 isoniazid Uncertain significance
ethionamide
inhA 1673730 c.-472C>G upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673736 c.-466G>C upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.7 isoniazid
ethionamide
inhA 1673751 c.-451G>A upstream_gene_variant 0.7 isoniazid
ethionamide
inhA 1673756 c.-446A>C upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673767 c.-435A>G upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1673784 c.-418G>C upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 0.76 isoniazid
ethionamide
inhA 1673832 c.-370A>G upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.76 isoniazid
ethionamide
inhA 1673856 c.-346T>C upstream_gene_variant 0.82 isoniazid
ethionamide
inhA 1673870 c.-332G>C upstream_gene_variant 0.82 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.77 isoniazid
ethionamide
inhA 1673916 c.-286A>G upstream_gene_variant 0.8 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.8 isoniazid
ethionamide
inhA 1673943 c.-259C>G upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1673950 c.-252C>A upstream_gene_variant 0.79 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.79 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1674006 c.-196T>C upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1674012 c.-190C>G upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.76 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 0.82 isoniazid
ethionamide
inhA 1674037 c.-165C>G upstream_gene_variant 0.84 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.79 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.76 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674093 c.-109C>G upstream_gene_variant 0.68 isoniazid
ethionamide
inhA 1674096 c.-106G>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674114 c.-88T>G upstream_gene_variant 0.71 isoniazid
ethionamide
inhA 1674123 c.-79T>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674129 c.-73C>T upstream_gene_variant 0.7 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674141 c.-61T>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674177 c.-25C>T upstream_gene_variant 0.67 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674184 c.-18delCinsGGG upstream_gene_variant 0.53 isoniazid
ethionamide
inhA 1674191 c.-11C>G upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1674199 c.-3C>G upstream_gene_variant 0.58 isoniazid Uncertain significance
ethionamide
inhA 1674205 p.Thr2Ala missense_variant 0.64 isoniazid Uncertain significance
ethionamide
inhA 1674216 c.15G>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674219 p.Asp6Glu missense_variant 0.69 isoniazid
ethionamide
inhA 1674231 c.30T>C synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674237 c.36T>C synonymous_variant 0.71 isoniazid
ethionamide
inhA 1674239 p.Ser13Thr missense_variant 0.71 isoniazid
ethionamide
inhA 1674243 c.42A>G synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674258 c.57G>C synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674279 c.78A>G synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674285 c.84A>G synonymous_variant 0.73 isoniazid
ethionamide
inhA 1674300 c.99C>G synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674304 p.Gln35Glu missense_variant 0.66 isoniazid
ethionamide
inhA 1674315 c.114C>G synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674321 c.120G>A synonymous_variant 0.65 isoniazid
ethionamide
inhA 1674342 c.141T>C synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674352 p.Thr51Ala missense_variant 0.72 isoniazid
ethionamide Uncertain significance
inhA 1674367 p.Ala56Gln missense_variant 0.7 isoniazid
ethionamide
inhA 1674375 c.174C>G synonymous_variant 0.74 isoniazid
ethionamide
inhA 1674382 p.Leu61Ile missense_variant 0.76 isoniazid
ethionamide
inhA 1674387 c.186A>G synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674414 c.214_215delGC frameshift_variant 0.67 isoniazid
ethionamide
inhA 1674420 c.219_220delCTinsACCC frameshift_variant&missense_variant 0.67 isoniazid
ethionamide
inhA 1674428 p.Gly76Asp missense_variant 0.69 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674441 c.240G>A synonymous_variant 0.7 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674443 p.Ala81Val missense_variant 0.71 isoniazid
ethionamide
inhA 1674450 c.249G>C synonymous_variant 0.71 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 0.73 isoniazid
ethionamide
inhA 1674465 c.264C>T synonymous_variant 0.75 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674471 c.270G>C synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.82 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 0.82 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.83 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.84 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.86 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.82 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 0.82 isoniazid
ethionamide
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674663 c.462G>A synonymous_variant 0.77 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674743 p.Lys181Arg missense_variant 0.83 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.83 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674765 c.564C>G synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 0.82 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.82 isoniazid
ethionamide
inhA 1674783 c.582C>T synonymous_variant 0.83 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.85 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.82 isoniazid
ethionamide
inhA 1674825 c.624C>T synonymous_variant 0.82 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674834 c.633C>G synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674840 c.639C>G synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674849 p.Gln216His missense_variant 0.8 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674883 p.Ile228Leu missense_variant 0.74 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674909 c.708G>C synonymous_variant 0.65 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674939 c.738G>C synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674945 p.Asp248Glu missense_variant 0.43 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674963 c.762G>C synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674966 c.765T>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 0.39 isoniazid
ethionamide
inhA 1674970 p.Ile257Val missense_variant 0.39 isoniazid
ethionamide
inhA 1674993 c.792G>C synonymous_variant 0.38 isoniazid
ethionamide
rpsA 1833251 c.-291A>G upstream_gene_variant 0.62 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 0.57 pyrazinamide
rpsA 1833265 c.-277A>G upstream_gene_variant 0.57 pyrazinamide
rpsA 1833271 c.-271G>A upstream_gene_variant 0.55 pyrazinamide
rpsA 1833272 c.-270_-268delCGGinsACC upstream_gene_variant 0.54 pyrazinamide
rpsA 1833281 c.-261_-259delGCCinsACG upstream_gene_variant 0.56 pyrazinamide
rpsA 1833295 c.-247C>G upstream_gene_variant 0.56 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.59 pyrazinamide
rpsA 1833346 c.-196C>A upstream_gene_variant 0.62 pyrazinamide
rpsA 1833352 c.-190C>A upstream_gene_variant 0.62 pyrazinamide
rpsA 1833515 c.-27C>T upstream_gene_variant 0.43 pyrazinamide
rpsA 1833516 c.-26A>G upstream_gene_variant 0.43 pyrazinamide
rpsA 1833518 c.-24C>A upstream_gene_variant 0.43 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.82 pyrazinamide
rpsA 1833593 p.Ser18Thr missense_variant 0.81 pyrazinamide
rpsA 1833610 c.69C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.82 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.85 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.8 pyrazinamide
rpsA 1833943 c.402C>G synonymous_variant 0.84 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.82 pyrazinamide
rpsA 1833976 c.435C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.79 pyrazinamide
rpsA 1833982 c.441C>T synonymous_variant 0.79 pyrazinamide
rpsA 1833983 c.442C>T synonymous_variant 0.79 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.81 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.8 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 0.82 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.68 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.67 pyrazinamide
rpsA 1834170 p.Thr210Ser missense_variant 0.67 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.73 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.7 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGT synonymous_variant 0.67 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.83 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
rpsA 1834408 c.867C>T synonymous_variant 0.84 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.82 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.81 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.81 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834657 c.1116G>A synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
rpsA 1834669 c.1128G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834684 c.1143C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.65 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.65 pyrazinamide
rpsA 1834741 c.1200C>G synonymous_variant 0.65 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.65 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.65 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.63 pyrazinamide
rpsA 1834766 p.Lys409Ala missense_variant 0.63 pyrazinamide
rpsA 1834775 p.Ala412Gln missense_variant 0.63 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.63 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834798 c.1257C>G synonymous_variant 0.69 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.7 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.77 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.78 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.73 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.75 linezolid
tsnR 1853418 c.-188_-186delCTTinsTTG upstream_gene_variant 0.78 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.73 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.68 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.68 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.6 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.6 linezolid
tsnR 1853492 c.-114G>C upstream_gene_variant 0.54 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.51 linezolid
tsnR 1853502 c.-104_-102delACCinsGCG upstream_gene_variant 0.51 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 0.51 linezolid
tsnR 1853522 c.-84C>G upstream_gene_variant 0.47 linezolid
tsnR 1853525 c.-81G>C upstream_gene_variant 0.49 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 0.47 linezolid
tsnR 1853540 c.-66A>C upstream_gene_variant 0.42 linezolid
tsnR 1853974 c.369C>T synonymous_variant 1.0 linezolid Not assoc w R
tsnR 1854045 p.Tyr147Cys missense_variant 0.95 linezolid Not assoc w R
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917908 c.-32C>G upstream_gene_variant 0.27 capreomycin
tlyA 1917934 c.-6T>C upstream_gene_variant 0.29 capreomycin
tlyA 1917948 c.9A>G synonymous_variant 0.31 capreomycin
tlyA 1917951 c.12T>C synonymous_variant 0.3 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917996 c.57A>C synonymous_variant 0.31 capreomycin
tlyA 1917999 c.60T>C synonymous_variant 0.31 capreomycin
tlyA 1918023 c.84C>T synonymous_variant 0.32 capreomycin Not assoc w R - Interim
tlyA 1918296 c.357G>C synonymous_variant 0.33 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.51 capreomycin
tlyA 1918317 c.378T>C synonymous_variant 0.5 capreomycin
tlyA 1918323 c.384G>C synonymous_variant 0.49 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.5 capreomycin
tlyA 1918330 p.Leu131Ala missense_variant 0.5 capreomycin
tlyA 1918347 c.408A>C synonymous_variant 0.54 capreomycin Not assoc w R - Interim
tlyA 1918350 c.411T>C synonymous_variant 0.51 capreomycin
tlyA 1918352 p.Gly138Asp missense_variant 0.51 capreomycin
tlyA 1918356 c.417C>G synonymous_variant 0.51 capreomycin
tlyA 1918359 c.420A>G synonymous_variant 0.5 capreomycin
tlyA 1918362 c.423G>C synonymous_variant 0.53 capreomycin
tlyA 1918365 p.Glu142Asp missense_variant 0.53 capreomycin
tlyA 1918377 c.438T>G synonymous_variant 0.55 capreomycin
tlyA 1918379 p.Arg147Pro missense_variant 0.54 capreomycin
tlyA 1918392 c.453A>G synonymous_variant 0.49 capreomycin Not assoc w R - Interim
tlyA 1918416 c.477G>C synonymous_variant 0.49 capreomycin
tlyA 1918417 c.478T>C synonymous_variant 0.49 capreomycin
tlyA 1918422 c.483T>C synonymous_variant 0.5 capreomycin
tlyA 1918429 c.490T>C synonymous_variant 0.49 capreomycin
tlyA 1918441 p.Val168Ile missense_variant 0.45 capreomycin
bacA 2062922 p.Ile603Val missense_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Not assoc w R
amikacin Not assoc w R
bacA 2063203 p.Asp509Gly missense_variant 0.43 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063205 c.1524T>C synonymous_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063211 p.Thr506Ser missense_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063214 c.1515G>C synonymous_variant 0.48 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063254 p.Glu492Ala missense_variant 0.57 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063266 p.Gly488Asp missense_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063268 c.1461G>C synonymous_variant 0.65 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063271 c.1458G>C synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063275 p.His485Cys missense_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063280 c.1449C>G synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063283 c.1446G>C synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063289 c.1440A>G synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063303 c.1426C>T synonymous_variant 0.62 kanamycin Not assoc w R - Interim
capreomycin
streptomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
bacA 2063304 c.1425A>G synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063307 c.1422G>C synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063313 c.1416T>C synonymous_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063325 c.1404G>C synonymous_variant 0.65 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064927 c.-199G>C upstream_gene_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.61 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.66 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064951 c.-223C>G upstream_gene_variant 0.66 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-253_-251delGGCinsTGT upstream_gene_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064987 c.-259G>C upstream_gene_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101726 c.1317A>G synonymous_variant 0.48 isoniazid
delamanid
ethionamide
ndh 2101729 c.1314G>C synonymous_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2101732 c.1311T>C synonymous_variant 0.48 isoniazid
delamanid
ethionamide
ndh 2101735 c.1308A>G synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2101744 p.Asp433Glu missense_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2101753 c.1290C>G synonymous_variant 0.51 isoniazid
delamanid
ethionamide
ndh 2101765 c.1278C>G synonymous_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2101768 c.1275C>G synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2101771 c.1272T>G synonymous_variant 0.5 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2101774 c.1269T>C synonymous_variant 0.49 isoniazid
delamanid
ethionamide
ndh 2101777 c.1266C>G synonymous_variant 0.49 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.53 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 0.61 isoniazid
delamanid
ethionamide
ndh 2101838 p.Ala402Val missense_variant 0.64 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101840 c.1203G>C synonymous_variant 0.62 isoniazid
delamanid
ethionamide
ndh 2101858 p.Ile395Met missense_variant 0.61 isoniazid
delamanid
ethionamide
ndh 2101873 c.1170T>C synonymous_variant 0.63 isoniazid
delamanid
ethionamide
ndh 2101888 p.Val385Leu missense_variant 0.63 isoniazid
delamanid
ethionamide
ndh 2101891 c.1152C>G synonymous_variant 0.63 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.65 isoniazid
delamanid
ethionamide
ndh 2101906 c.1137G>C synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2101912 c.1131G>C synonymous_variant 0.73 isoniazid
delamanid
ethionamide
ndh 2101915 c.1128T>C synonymous_variant 0.73 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101920 c.1123A>C synonymous_variant 0.75 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>C synonymous_variant 0.75 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>G synonymous_variant 0.77 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2101966 c.1077T>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2101969 c.1074G>A synonymous_variant 0.79 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.76 isoniazid
delamanid
ethionamide
ndh 2101980 p.Asn355Asp missense_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2101984 c.1059C>G synonymous_variant 0.75 isoniazid
delamanid
ethionamide
ndh 2101988 p.Ala352Gly missense_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2101993 c.1050A>G synonymous_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2102005 c.1038G>C synonymous_variant 0.78 isoniazid
delamanid
ethionamide
ndh 2102020 c.1023A>G synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2102023 c.1020G>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102026 c.1017G>C synonymous_variant 0.79 isoniazid
delamanid
ethionamide
ndh 2102050 c.993T>C synonymous_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2102059 c.984T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 0.65 isoniazid
delamanid
ethionamide
ndh 2102068 c.975T>C synonymous_variant 0.62 isoniazid
delamanid
ethionamide
ndh 2102077 c.966T>C synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2102083 c.960G>C synonymous_variant 0.51 isoniazid
delamanid
ethionamide
ndh 2102086 c.957G>C synonymous_variant 0.51 isoniazid
delamanid
ethionamide
ndh 2102101 p.Tyr314His missense_variant 0.51 isoniazid
delamanid
ethionamide
ndh 2102110 c.933T>C synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2102113 c.930C>G synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102125 c.918G>C synonymous_variant 0.45 isoniazid
delamanid
ethionamide
ndh 2102128 c.915G>T synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2102131 p.Gln304Lys missense_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2102146 c.897G>C synonymous_variant 0.4 isoniazid
delamanid
ethionamide
ndh 2102227 c.816C>G synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102263 p.Lys260Arg missense_variant 0.46 isoniazid
delamanid
ethionamide
ndh 2102266 c.777C>G synonymous_variant 0.46 isoniazid
delamanid
ethionamide
ndh 2102275 c.768C>G synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2102287 c.756C>G synonymous_variant 0.58 isoniazid
delamanid
ethionamide
ndh 2102302 c.741G>C synonymous_variant 0.62 isoniazid
delamanid
ethionamide
ndh 2102305 c.738T>C synonymous_variant 0.62 isoniazid
delamanid
ethionamide
ndh 2102317 c.726A>G synonymous_variant 0.58 isoniazid
delamanid
ethionamide
ndh 2102320 c.723G>C synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2102328 p.Leu239Met missense_variant 0.54 isoniazid
delamanid
ethionamide
ndh 2102334 p.Gln237Glu missense_variant 0.54 isoniazid
delamanid
ethionamide
ndh 2102337 c.706T>C synonymous_variant 0.54 isoniazid
delamanid
ethionamide Not assoc w R - Interim
ndh 2102341 c.702C>G synonymous_variant 0.54 isoniazid
delamanid
ethionamide
ndh 2102344 p.Ala233Arg missense_variant 0.54 isoniazid
delamanid
ethionamide
ndh 2102355 p.Gln230Glu missense_variant 0.58 isoniazid
delamanid
ethionamide
ndh 2102366 p.Ala226Glu missense_variant 0.62 isoniazid Uncertain significance
delamanid
ethionamide
ndh 2102377 c.666A>G synonymous_variant 0.65 isoniazid
delamanid
ethionamide
ndh 2102382 c.661C>T synonymous_variant 0.68 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102386 c.657G>C synonymous_variant 0.67 isoniazid
delamanid
ethionamide
ndh 2102401 c.642T>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102407 c.636T>C synonymous_variant 0.67 isoniazid
delamanid
ethionamide
ndh 2102420 p.Lys208Arg missense_variant 0.53 isoniazid
delamanid
ethionamide
ndh 2102443 c.600A>G synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102455 c.588G>C synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2102461 c.582G>A synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102469 c.574C>T synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102470 c.573G>A synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102482 c.561A>G synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102494 c.549T>C synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2102497 c.546T>C synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102512 c.531G>C synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102518 c.525T>G synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102566 c.477A>G synonymous_variant 0.51 isoniazid
delamanid
ethionamide
ndh 2102572 c.471A>G synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2102581 c.462T>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102590 c.453A>C synonymous_variant 0.62 isoniazid
delamanid
ethionamide
ndh 2102593 c.450C>G synonymous_variant 0.64 isoniazid
delamanid
ethionamide
ndh 2102599 c.444T>G synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2102604 c.439T>C synonymous_variant 0.68 isoniazid
delamanid
ethionamide
ndh 2102610 c.433T>C synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2102623 c.420C>G synonymous_variant 0.69 isoniazid
delamanid
ethionamide
ndh 2102635 c.408C>G synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2102638 c.405A>C synonymous_variant 0.71 isoniazid
delamanid
ethionamide
ndh 2102644 c.399A>G synonymous_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2102668 c.375T>C synonymous_variant 0.78 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102680 c.363T>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2102683 c.360T>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
ndh 2102710 c.333C>T synonymous_variant 0.79 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 0.74 isoniazid
delamanid
ethionamide
ndh 2102728 c.315T>C synonymous_variant 0.72 isoniazid
delamanid
ethionamide
ndh 2102737 c.306A>G synonymous_variant 0.64 isoniazid
delamanid
ethionamide
ndh 2102740 c.303G>C synonymous_variant 0.64 isoniazid
delamanid
ethionamide
ndh 2102743 c.300C>G synonymous_variant 0.63 isoniazid
delamanid
ethionamide
ndh 2102749 p.Cys98Thr missense_variant 0.61 isoniazid
delamanid
ethionamide
ndh 2102755 p.Gly96Arg missense_variant 0.63 isoniazid
delamanid
ethionamide
ndh 2102787 c.256T>C synonymous_variant 0.64 isoniazid
delamanid
ethionamide
ndh 2102791 c.252A>G synonymous_variant 0.65 isoniazid
delamanid
ethionamide
ndh 2102800 c.243T>C synonymous_variant 0.64 isoniazid
delamanid
ethionamide
ndh 2102812 c.231T>C synonymous_variant 0.61 isoniazid
delamanid
ethionamide
ndh 2102821 c.222C>G synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102824 c.219G>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102830 c.213G>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102836 c.207T>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102842 c.201A>G synonymous_variant 0.58 isoniazid
delamanid
ethionamide
ndh 2102845 c.198A>C synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2102857 c.186T>C synonymous_variant 0.53 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 0.53 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102872 c.171A>G synonymous_variant 0.52 isoniazid
delamanid
ethionamide
ndh 2102875 c.168C>T synonymous_variant 0.53 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102899 c.144T>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2102911 c.132G>C synonymous_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2102919 p.Leu42Met missense_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2102929 c.114T>C synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102938 p.Arg35His missense_variant 0.44 isoniazid
delamanid
ethionamide
ndh 2102962 c.81A>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102965 c.78G>A synonymous_variant 0.36 isoniazid
delamanid
ethionamide
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2154984 c.1128G>C synonymous_variant 0.32 isoniazid
katG 2154992 p.Ser374Ala missense_variant 0.27 isoniazid
katG 2154993 c.1119C>T synonymous_variant 0.27 isoniazid Not assoc w R - Interim
katG 2154996 c.1116G>T synonymous_variant 0.27 isoniazid
katG 2154999 c.1113A>G synonymous_variant 0.3 isoniazid
katG 2155017 c.1095G>C synonymous_variant 0.47 isoniazid
katG 2155029 c.1083C>G synonymous_variant 0.54 isoniazid
katG 2155032 c.1080T>G synonymous_variant 0.55 isoniazid Not assoc w R - Interim
katG 2155056 c.1056A>G synonymous_variant 0.55 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.62 isoniazid
katG 2155068 c.1044T>C synonymous_variant 0.63 isoniazid
katG 2155071 c.1041T>G synonymous_variant 0.64 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.67 isoniazid
katG 2155083 c.1029G>C synonymous_variant 0.66 isoniazid
katG 2155113 c.999C>G synonymous_variant 0.61 isoniazid
katG 2155119 c.993T>C synonymous_variant 0.6 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.62 isoniazid Not assoc w R - Interim
katG 2155134 c.978G>C synonymous_variant 0.62 isoniazid
katG 2155140 c.972C>A synonymous_variant 0.6 isoniazid
katG 2155144 p.Asn323Pro missense_variant 0.61 isoniazid
katG 2155152 c.960A>C synonymous_variant 0.63 isoniazid
katG 2155155 c.957C>G synonymous_variant 0.64 isoniazid
katG 2155176 c.936G>C synonymous_variant 0.66 isoniazid
katG 2155185 c.927T>C synonymous_variant 0.62 isoniazid
katG 2155188 p.Thr308Lys missense_variant 0.64 isoniazid
katG 2155191 c.921A>C synonymous_variant 0.64 isoniazid
katG 2155196 p.Thr306Ser missense_variant 0.65 isoniazid
katG 2155221 c.891C>G synonymous_variant 0.55 isoniazid
katG 2155225 p.Met296Gln missense_variant 0.54 isoniazid
katG 2155233 p.Leu293Ile missense_variant 0.54 isoniazid
katG 2155239 c.873T>C synonymous_variant 0.55 isoniazid
katG 2155242 c.870T>C synonymous_variant 0.58 isoniazid
katG 2155251 c.861A>G synonymous_variant 0.62 isoniazid
katG 2155257 c.855C>T synonymous_variant 0.57 isoniazid
katG 2155266 c.846T>C synonymous_variant 0.54 isoniazid
katG 2155272 p.Pro280Asp missense_variant 0.48 isoniazid
katG 2155284 c.828T>C synonymous_variant 0.39 isoniazid
katG 2155293 c.819T>C synonymous_variant 0.41 isoniazid
katG 2155566 c.546G>C synonymous_variant 0.56 isoniazid Not assoc w R - Interim
katG 2155581 c.531C>G synonymous_variant 0.68 isoniazid
katG 2155590 c.522A>G synonymous_variant 0.73 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.72 isoniazid
katG 2155614 p.Val166Ile missense_variant 0.74 isoniazid Uncertain significance
katG 2155617 c.495T>C synonymous_variant 0.74 isoniazid Not assoc w R - Interim
katG 2155626 c.486G>C synonymous_variant 0.78 isoniazid
katG 2155632 c.480A>T synonymous_variant 0.79 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.77 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.79 isoniazid Uncertain significance
katG 2155680 c.432G>C synonymous_variant 0.78 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.76 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.76 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.7 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.65 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.62 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.57 isoniazid
katG 2155736 p.Met126Leu missense_variant 0.54 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.48 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.5 isoniazid
katG 2155765 p.His116Phe missense_variant 0.5 isoniazid
katG 2155773 c.339C>T synonymous_variant 0.45 isoniazid Not assoc w R - Interim
PPE35 2167983 p.Gly877Asp missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517941 c.-174C>G upstream_gene_variant 0.78 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.79 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.78 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.78 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.73 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.7 isoniazid
kasA 2518031 c.-84G>C upstream_gene_variant 0.68 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.67 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.67 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.67 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.67 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 0.67 isoniazid
kasA 2518061 c.-54G>C upstream_gene_variant 0.7 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.75 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.67 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.66 isoniazid
kasA 2518100 c.-15T>G upstream_gene_variant 0.6 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 0.57 isoniazid
kasA 2518106 c.-9C>G upstream_gene_variant 0.57 isoniazid
kasA 2518109 c.-6G>C upstream_gene_variant 0.57 isoniazid
kasA 2518110 c.-5_-4delTCinsAG upstream_gene_variant 0.57 isoniazid
kasA 2518119 p.Ser2Thr missense_variant 0.59 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.55 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.74 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.76 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.81 isoniazid
kasA 2518183 c.69G>C synonymous_variant 0.84 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.83 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.81 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.84 isoniazid
kasA 2518261 c.147G>A synonymous_variant 0.82 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.79 isoniazid
kasA 2518282 c.168A>G synonymous_variant 0.78 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.78 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.8 isoniazid
kasA 2518300 c.186T>A synonymous_variant 0.79 isoniazid
kasA 2518312 p.Asp66Glu missense_variant 0.79 isoniazid
kasA 2518315 c.201G>C synonymous_variant 0.75 isoniazid
kasA 2518322 p.Ser70Ala missense_variant 0.7 isoniazid
kasA 2518336 c.222A>G synonymous_variant 0.67 isoniazid
kasA 2518339 c.225C>G synonymous_variant 0.67 isoniazid
kasA 2518343 p.Met77Leu missense_variant 0.67 isoniazid
kasA 2518357 c.243G>C synonymous_variant 0.7 isoniazid
kasA 2518379 c.265T>C synonymous_variant 0.66 isoniazid
kasA 2518385 p.Gly91Ser missense_variant 0.57 isoniazid
kasA 2518390 c.276A>C synonymous_variant 0.59 isoniazid
kasA 2518394 c.280_282delCTAinsTTG synonymous_variant 0.59 isoniazid
kasA 2518403 p.Ser97Asn missense_variant 0.61 isoniazid
kasA 2518408 c.294C>G synonymous_variant 0.64 isoniazid
kasA 2518426 c.312T>C synonymous_variant 0.66 isoniazid
kasA 2518429 c.315A>C synonymous_variant 0.65 isoniazid
kasA 2518435 c.321G>C synonymous_variant 0.66 isoniazid
kasA 2518439 p.Ala109Thr missense_variant 0.62 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.62 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.62 isoniazid
kasA 2518456 c.342C>G synonymous_variant 0.66 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.62 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.6 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.68 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.69 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.67 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.7 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.67 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.67 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.67 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.72 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.76 isoniazid
kasA 2518570 p.ValIle153ThrVal missense_variant 0.73 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.73 isoniazid
kasA 2518585 c.471G>A synonymous_variant 0.74 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.76 isoniazid
kasA 2518600 c.486C>G synonymous_variant 0.8 isoniazid
kasA 2518603 c.489G>C synonymous_variant 0.79 isoniazid
kasA 2518612 c.498C>G synonymous_variant 0.81 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.85 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.86 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.85 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.84 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.83 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.86 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.84 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.84 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.81 isoniazid
kasA 2518708 c.594C>G synonymous_variant 0.83 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.83 isoniazid
kasA 2518714 c.600A>T synonymous_variant 0.85 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.84 isoniazid
kasA 2518756 c.642G>T synonymous_variant 0.82 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.83 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.82 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.8 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.81 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.81 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.8 isoniazid
kasA 2518849 c.735G>C synonymous_variant 0.79 isoniazid
kasA 2518855 c.741C>G synonymous_variant 0.79 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.77 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.71 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.71 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.67 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.57 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.55 isoniazid
kasA 2518915 c.801T>C synonymous_variant 0.59 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.59 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.47 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.46 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.44 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.53 isoniazid
kasA 2519125 c.1011C>T synonymous_variant 0.52 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.62 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 0.64 isoniazid
kasA 2519170 c.1056G>T synonymous_variant 0.62 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.62 isoniazid
kasA 2519176 c.1062G>A synonymous_variant 0.59 isoniazid
kasA 2519179 c.1065G>C synonymous_variant 0.59 isoniazid
kasA 2519182 c.1068G>T synonymous_variant 0.59 isoniazid
kasA 2519183 c.1069_1071delCTCinsTTG synonymous_variant 0.59 isoniazid
kasA 2519191 c.1077G>A synonymous_variant 0.59 isoniazid
kasA 2519192 c.1078C>T synonymous_variant 0.59 isoniazid
kasA 2519197 c.1083G>C synonymous_variant 0.61 isoniazid
kasA 2519200 c.1086G>T synonymous_variant 0.68 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.68 isoniazid
kasA 2519215 c.1101C>A synonymous_variant 0.77 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.76 isoniazid
kasA 2519225 c.1111C>T synonymous_variant 0.75 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.74 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 0.72 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.72 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 0.69 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.66 isoniazid
kasA 2519287 c.1173T>C synonymous_variant 0.63 isoniazid
kasA 2519293 p.Asp393Glu missense_variant 0.54 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 0.51 isoniazid
kasA 2519299 c.1185C>T synonymous_variant 0.51 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 0.5 isoniazid
kasA 2519306 p.Val398Ile missense_variant 0.49 isoniazid
kasA 2519323 c.1209G>A synonymous_variant 0.4 isoniazid
kasA 2519329 c.1215C>T synonymous_variant 0.4 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 0.4 isoniazid
kasA 2519347 c.1233T>G synonymous_variant 0.38 isoniazid
kasA 2519350 c.1236C>A synonymous_variant 0.31 isoniazid
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0 isoniazid
ahpC 2726204 c.12A>G synonymous_variant 0.34 isoniazid
ahpC 2726210 c.18T>C synonymous_variant 0.38 isoniazid Not assoc w R - Interim
ahpC 2726216 c.24T>C synonymous_variant 0.41 isoniazid
ahpC 2726243 c.51T>C synonymous_variant 0.62 isoniazid
ahpC 2726246 c.54C>G synonymous_variant 0.65 isoniazid
ahpC 2726255 c.63T>C synonymous_variant 0.66 isoniazid Not assoc w R - Interim
ahpC 2726264 c.72C>G synonymous_variant 0.71 isoniazid
ahpC 2726303 c.111T>G synonymous_variant 0.74 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.74 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.73 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.73 isoniazid
ahpC 2726324 c.132A>C synonymous_variant 0.74 isoniazid
ahpC 2726336 c.144G>C synonymous_variant 0.72 isoniazid
ahpC 2726342 c.150G>C synonymous_variant 0.71 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.71 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 0.67 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.68 isoniazid Not assoc w R - Interim
ahpC 2726375 c.183C>T synonymous_variant 0.58 isoniazid
ahpC 2726378 c.186T>C synonymous_variant 0.56 isoniazid
ahpC 2726381 c.189C>G synonymous_variant 0.55 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 0.56 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 0.53 isoniazid
ahpC 2726423 c.231C>T synonymous_variant 0.35 isoniazid
ahpC 2726621 c.429G>A synonymous_variant 0.38 isoniazid Not assoc w R - Interim
ahpC 2726627 c.435G>A synonymous_variant 0.39 isoniazid
ahpC 2726639 c.447C>G synonymous_variant 0.41 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 0.43 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.43 isoniazid
ahpC 2726657 c.465A>G synonymous_variant 0.43 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.38 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.33 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.33 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.35 isoniazid
ahpC 2726684 c.492G>C synonymous_variant 0.35 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.33 isoniazid
ahpC 2726693 c.501C>T synonymous_variant 0.32 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.32 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 0.32 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.35 isoniazid
folC 2746282 c.1317T>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746306 p.Arg431Thr missense_variant 0.45 para-aminosalicylic_acid
folC 2746312 c.1287G>C synonymous_variant 0.47 para-aminosalicylic_acid
folC 2746331 p.Glu423Gly missense_variant 0.61 para-aminosalicylic_acid
folC 2746335 p.Gly422Arg missense_variant 0.6 para-aminosalicylic_acid
folC 2746336 c.1263C>G synonymous_variant 0.6 para-aminosalicylic_acid
folC 2746342 p.Leu419Val missense_variant 0.6 para-aminosalicylic_acid
folC 2746351 c.1248C>G synonymous_variant 0.63 para-aminosalicylic_acid
folC 2746360 c.1239T>C synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746369 c.1230G>C synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746378 c.1221G>T synonymous_variant 0.63 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.58 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.6 para-aminosalicylic_acid
folC 2746409 p.Val397Ala missense_variant 0.61 para-aminosalicylic_acid
folC 2746411 c.1188G>C synonymous_variant 0.62 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746428 c.1171C>T synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746429 c.1170C>T synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746438 c.1161G>T synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.63 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.47 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 0.55 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746630 p.Gly323Val missense_variant 0.67 para-aminosalicylic_acid
folC 2746654 c.945C>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2746672 c.927C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2746675 p.Ser308Ala missense_variant 0.75 para-aminosalicylic_acid
folC 2746678 c.921T>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2746687 p.Leu304Val missense_variant 0.7 para-aminosalicylic_acid
folC 2746691 p.Val303Ala missense_variant 0.71 para-aminosalicylic_acid
folC 2746711 c.888A>G synonymous_variant 0.6 para-aminosalicylic_acid
folC 2746714 c.885T>C synonymous_variant 0.6 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.54 para-aminosalicylic_acid
folC 2747341 c.258C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747368 c.231G>T synonymous_variant 0.69 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747401 c.198G>C synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 0.79 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 0.81 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747425 c.174C>G synonymous_variant 0.81 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 0.73 para-aminosalicylic_acid
folC 2747476 c.123C>G synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747479 c.120G>A synonymous_variant 0.73 para-aminosalicylic_acid
folC 2747482 c.117G>C synonymous_variant 0.72 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 0.61 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747506 c.93G>A synonymous_variant 0.58 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747521 c.78C>G synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747533 c.66C>T synonymous_variant 0.54 para-aminosalicylic_acid
folC 2747539 c.60T>A synonymous_variant 0.48 para-aminosalicylic_acid
folC 2747760 c.-162G>C upstream_gene_variant 0.37 para-aminosalicylic_acid
folC 2747766 c.-168A>G upstream_gene_variant 0.5 para-aminosalicylic_acid
folC 2747775 c.-177C>G upstream_gene_variant 0.58 para-aminosalicylic_acid
folC 2747778 c.-180T>C upstream_gene_variant 0.61 para-aminosalicylic_acid
folC 2747790 c.-192G>C upstream_gene_variant 0.62 para-aminosalicylic_acid
Rv2477c 2782501 c.1542T>C synonymous_variant 0.33 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782504 c.1539G>A synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782510 c.1533G>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782573 c.1470C>T synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782579 c.1464C>T synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782582 p.Asn487Lys missense_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782585 p.Leu486Glu missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782608 p.Gly479Ser missense_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782609 c.1434G>C synonymous_variant 0.57 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782612 c.1431T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782714 c.1329A>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782720 c.1323T>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782777 c.1266A>G synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782790 p.Thr418Ser missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782792 c.1251A>G synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782795 c.1248T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782803 p.Gln414Glu missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782807 c.1236T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782831 c.1212G>A synonymous_variant 0.67 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782837 c.1206C>G synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782849 c.1194G>C synonymous_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 p.Ala394Ser missense_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782905 p.Val380Ile missense_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782924 c.1119G>C synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.78 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>G synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782996 c.1047C>T synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782999 c.1044C>A synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783014 p.Ser343Thr missense_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783038 p.Ala335Thr missense_variant 0.83 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783059 c.984T>C synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783071 c.972C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783080 c.963G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783083 c.960G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.69 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783107 c.936G>C synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783128 c.915C>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.54 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783173 c.870C>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783206 c.837G>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783212 c.831C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783239 p.Glu268Asp missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783242 p.Thr267Gln missense_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783248 c.795G>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783341 c.702C>G synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783407 c.636C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>G synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783431 p.Ser204Ala missense_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783443 c.600G>A synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783455 c.588G>A synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.74 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783569 c.474C>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783578 p.Glu155Asp missense_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783584 p.Ala153Pro missense_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783644 p.Asp133Glu missense_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783767 c.276C>G synonymous_variant 0.84 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>G synonymous_variant 0.89 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783944 c.99G>A synonymous_variant 0.81 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 0.77 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783986 c.57G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.72 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784396 c.-354A>T upstream_gene_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784399 c.-357G>C upstream_gene_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784438 c.-396G>C upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784441 c.-399G>A upstream_gene_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784468 c.-426C>G upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784489 c.-447C>A upstream_gene_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784511 c.-470_-469delAGinsGC upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784516 c.-474C>G upstream_gene_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784549 c.-509_-507delGTCinsATG upstream_gene_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859887 p.Ala178Ser missense_variant 0.6 bedaquiline
clofazimine
pepQ 2860146 c.273C>A synonymous_variant 0.38 bedaquiline
clofazimine
pepQ 2860161 c.258G>C synonymous_variant 0.42 bedaquiline
clofazimine
pepQ 2860167 c.252C>G synonymous_variant 0.42 bedaquiline
clofazimine
pepQ 2860170 c.249G>C synonymous_variant 0.39 bedaquiline
clofazimine
pepQ 2860185 c.234G>C synonymous_variant 0.33 bedaquiline
clofazimine
pepQ 2860188 c.231C>G synonymous_variant 0.33 bedaquiline
clofazimine
pepQ 2860197 c.222T>C synonymous_variant 0.36 bedaquiline
clofazimine
pepQ 2860200 c.219G>C synonymous_variant 0.36 bedaquiline
clofazimine
pepQ 2860203 c.216A>G synonymous_variant 0.36 bedaquiline
clofazimine
pepQ 2860209 c.210C>T synonymous_variant 0.35 bedaquiline
clofazimine
pepQ 2860222 p.Ser66Lys missense_variant 0.33 bedaquiline
clofazimine
pepQ 2860233 c.186T>C synonymous_variant 0.35 bedaquiline
clofazimine
pepQ 2860236 c.183C>G synonymous_variant 0.35 bedaquiline
clofazimine
pepQ 2860259 c.160T>C synonymous_variant 0.36 bedaquiline
clofazimine
ribD 2987438 c.600G>C synonymous_variant 0.31 para-aminosalicylic_acid
ribD 2987441 c.603A>G synonymous_variant 0.3 para-aminosalicylic_acid
ribD 2987448 p.Glu204Gln missense_variant 0.37 para-aminosalicylic_acid
ribD 2987453 c.615T>C synonymous_variant 0.39 para-aminosalicylic_acid
ribD 2987457 p.Val207Leu missense_variant 0.41 para-aminosalicylic_acid
ribD 2987471 c.633G>C synonymous_variant 0.42 para-aminosalicylic_acid
ribD 2987474 c.636T>C synonymous_variant 0.43 para-aminosalicylic_acid
ribD 2987486 c.648C>G synonymous_variant 0.42 para-aminosalicylic_acid
ribD 2987493 p.Val219Leu missense_variant 0.42 para-aminosalicylic_acid
ribD 2987513 c.675C>G synonymous_variant 0.44 para-aminosalicylic_acid
ribD 2987519 c.681A>C synonymous_variant 0.34 para-aminosalicylic_acid
ribD 2987521 p.Val228Ala missense_variant 0.34 para-aminosalicylic_acid
ribD 2987523 p.Thr229Ala missense_variant 0.34 para-aminosalicylic_acid
ribD 2987528 c.690A>C synonymous_variant 0.34 para-aminosalicylic_acid
ribD 2987531 c.693C>G synonymous_variant 0.37 para-aminosalicylic_acid
ribD 2987534 c.696G>C synonymous_variant 0.37 para-aminosalicylic_acid
ribD 2987549 c.711G>C synonymous_variant 0.29 para-aminosalicylic_acid
Rv2680 2996329 c.225T>C synonymous_variant 0.51 capreomycin Not assoc w R - Interim
Rv2681 2996344 c.-395C>G upstream_gene_variant 0.55 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.6 capreomycin
Rv2681 2996365 c.-374G>C upstream_gene_variant 0.6 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 0.6 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.57 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.57 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.57 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 0.6 capreomycin
Rv2681 2996398 c.-341C>G upstream_gene_variant 0.53 capreomycin
Rv2681 2996401 c.-338T>G upstream_gene_variant 0.54 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 0.54 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.41 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.4 capreomycin
Rv2680 2996438 p.Ser112Pro missense_variant 0.4 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.36 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 0.39 capreomycin Not assoc w R - Interim
Rv2681 2996467 c.-272C>G upstream_gene_variant 0.42 capreomycin
Rv2681 2996476 c.-263A>G upstream_gene_variant 0.3 capreomycin
Rv2681 2996584 c.-155G>T upstream_gene_variant 0.33 capreomycin
Rv2681 2996587 c.-152G>C upstream_gene_variant 0.33 capreomycin
Rv2681 2996593 c.-146T>C upstream_gene_variant 0.38 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 0.36 capreomycin
Rv2681 2996617 c.-122A>G upstream_gene_variant 0.34 capreomycin
Rv2680 2996631 p.Thr176Ser missense_variant 0.35 capreomycin
Rv2680 2996637 c.533_534insCG frameshift_variant 0.35 capreomycin Uncertain significance
Rv2680 2996640 p.Leu179Gln missense_variant 0.35 capreomycin
Rv2681 2996644 c.-95C>T upstream_gene_variant 0.35 capreomycin
Rv2680 2996647 c.543_546delCCATinsAC frameshift_variant&synonymous_variant 0.38 capreomycin Uncertain significance
Rv2680 2996654 p.Gln184Glu missense_variant 0.35 capreomycin Uncertain significance
Rv2680 2996668 p.Asp188Glu missense_variant 0.36 capreomycin
Rv2681 2996671 c.-68C>G upstream_gene_variant 0.35 capreomycin
Rv2681 2996686 c.-53C>G upstream_gene_variant 0.38 capreomycin
Rv2681 2996698 c.-41A>G upstream_gene_variant 0.32 capreomycin
Rv2680 2996699 p.Ala199Thr missense_variant 0.32 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 0.32 capreomycin
Rv2681 2996912 c.174C>T synonymous_variant 0.67 capreomycin Not assoc w R
Rv2681 2996927 c.189T>C synonymous_variant 0.29 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.33 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.38 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.39 capreomycin
Rv2681 2996972 c.234C>G synonymous_variant 0.4 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.4 capreomycin
Rv2681 2996984 c.246C>G synonymous_variant 0.42 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.41 capreomycin
Rv2681 2996990 c.252G>C synonymous_variant 0.41 capreomycin
Rv2681 2996991 p.Ile85Val missense_variant 0.44 capreomycin
Rv2681 2997014 c.276T>C synonymous_variant 0.54 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 0.56 capreomycin
Rv2681 2997026 c.288C>G synonymous_variant 0.58 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 0.56 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 0.55 capreomycin
Rv2681 2997053 c.315C>G synonymous_variant 0.45 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 0.45 capreomycin Uncertain significance
Rv2681 2997058 p.Thr107Ser missense_variant 0.45 capreomycin
Rv2681 2997060 p.Asn108Asp missense_variant 0.44 capreomycin
Rv2681 2997065 c.327G>A synonymous_variant 0.43 capreomycin
Rv2681 2997086 c.348T>C synonymous_variant 0.34 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 0.33 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 0.31 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 0.32 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 0.32 capreomycin Not assoc w R - Interim
Rv2681 2997128 c.390A>G synonymous_variant 0.31 capreomycin
Rv2681 2997131 c.393G>C synonymous_variant 0.31 capreomycin
Rv2681 2997134 c.396A>C synonymous_variant 0.33 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.29 capreomycin
Rv2681 2997167 c.429G>A synonymous_variant 0.28 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 0.26 capreomycin
Rv2681 2997213 c.475C>T synonymous_variant 0.26 capreomycin
Rv2681 2997222 p.Thr162Ala missense_variant 0.31 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 0.36 capreomycin
Rv2681 2997267 p.Ser177Ala missense_variant 0.36 capreomycin
Rv2681 2997271 p.Ala178Glu missense_variant 0.35 capreomycin
Rv2681 2997291 c.553T>C synonymous_variant 0.33 capreomycin
Rv2681 2997299 c.561G>C synonymous_variant 0.31 capreomycin
Rv2752c 3064632 c.1560C>T synonymous_variant 0.69 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
Rv2752c 3065418 c.774A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065430 c.762A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065442 c.750T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065457 c.735A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065481 c.711T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065484 c.708G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065487 c.705T>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065490 c.702A>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065493 c.699G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065496 c.696G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065499 c.693A>C synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065508 c.684T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065517 c.675C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065529 c.663G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065532 c.660A>T synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065538 c.654G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065553 c.639A>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065568 c.624C>A synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065576 p.Ala206Ser missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065880 c.312C>T synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065901 c.291A>C synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065908 p.Lys95Arg missense_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065910 c.282C>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065916 c.276T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065922 c.270T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065946 p.Gly82Ala missense_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065957 c.235T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065982 c.210G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065988 c.204A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.72 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.78 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066065 p.Ile43Leu missense_variant 0.75 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 p.Ile42Val missense_variant 0.75 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066071 c.121T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066096 c.96G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066118 p.Asn25Ser missense_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066135 c.57C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066459 c.-268T>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066468 c.-277C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066471 c.-280A>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066481 c.-290C>G upstream_gene_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.66 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066590 c.-399A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066630 c.-439G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066636 c.-448_-445delGTCGinsCGAA upstream_gene_variant 0.75 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066651 c.-462_-460delATCinsCTG upstream_gene_variant 0.73 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066675 c.-485_-484delCGinsTC upstream_gene_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066681 c.-490G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066714 c.-523G>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066720 c.-529G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066940 c.-749C>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066966 c.-775C>G upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067249 p.Thr233Ser missense_variant 0.42 para-aminosalicylic_acid
thyX 3067250 c.696G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067262 c.684C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067271 c.675G>C synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067277 c.669C>A synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067280 c.666G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 0.61 para-aminosalicylic_acid
thyX 3067287 p.Ala220Val missense_variant 0.63 para-aminosalicylic_acid
thyX 3067293 p.Gln218Arg missense_variant 0.64 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067310 c.636C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067577 p.Glu123Asp missense_variant 0.5 para-aminosalicylic_acid
thyX 3067586 c.360C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067592 c.354G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067610 p.Lys112Gly missense_variant 0.61 para-aminosalicylic_acid
thyX 3067619 c.327A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067622 c.324C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067628 c.318G>A synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067748 p.Asp66Glu missense_variant 0.68 para-aminosalicylic_acid
thyX 3067762 c.184C>A synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.68 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067796 c.150C>G synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3073851 c.621C>T synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.5 para-aminosalicylic_acid
thyA 3073888 p.Ser195Arg missense_variant 0.57 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3073950 c.522G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073962 c.510G>T synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.65 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073998 c.474G>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074052 c.417_420delGCGGinsAA frameshift_variant&missense_variant 0.52 para-aminosalicylic_acid
thyA 3074058 c.413_414insTC frameshift_variant 0.52 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.53 para-aminosalicylic_acid
thyA 3074076 c.396C>T synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 0.51 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 0.6 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.47 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3074159 p.Ser105Thr missense_variant 0.46 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.47 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074196 c.276G>A synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.54 para-aminosalicylic_acid
thyA 3074211 c.261A>G synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3074214 p.Asp86Ser missense_variant 0.52 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3074253 p.His73Gln missense_variant 0.64 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 0.57 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.47 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3074285 c.187T>C synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074305 p.Ala56Val missense_variant 0.63 para-aminosalicylic_acid
thyA 3074307 c.165A>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074322 c.150C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3074325 c.147A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074337 c.135C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074367 c.105C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074372 p.Met34Leu missense_variant 0.59 para-aminosalicylic_acid
thyA 3074397 c.75A>G synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074400 c.72C>G synonymous_variant 0.52 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087608 c.789A>G synonymous_variant 0.33 cycloserine
ald 3087617 c.798T>C synonymous_variant 0.33 cycloserine
ald 3087620 c.801A>C synonymous_variant 0.34 cycloserine
ald 3087641 c.822T>C synonymous_variant 0.51 cycloserine
ald 3087647 c.828A>G synonymous_variant 0.5 cycloserine
ald 3087649 p.Gly277Asp missense_variant 0.49 cycloserine
ald 3087653 c.834A>G synonymous_variant 0.51 cycloserine
ald 3087659 c.840G>C synonymous_variant 0.52 cycloserine
ald 3087666 p.Tyr283His missense_variant 0.53 cycloserine
ald 3087672 p.His285Asp missense_variant 0.57 cycloserine
ald 3087698 c.879G>C synonymous_variant 0.58 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.55 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.59 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.59 cycloserine
ald 3087737 c.918G>C synonymous_variant 0.59 cycloserine
ald 3087750 p.Tyr311Val missense_variant 0.53 cycloserine
ald 3087764 c.945C>T synonymous_variant 0.42 cycloserine
Rv3083 3448714 p.Asp71His missense_variant 1.0 ethionamide Uncertain significance
lpqB 3623273 c.1638T>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3623279 c.1632T>G synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3623299 p.Ile538Val missense_variant 0.45 rifampicin
bedaquiline
lpqB 3623302 p.Ala537Thr missense_variant 0.44 rifampicin
bedaquiline
lpqB 3623305 p.Thr536Ser missense_variant 0.43 rifampicin
bedaquiline
lpqB 3623308 p.Leu535Val missense_variant 0.44 rifampicin Uncertain significance
bedaquiline
lpqB 3623309 c.1602A>G synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623312 c.1599T>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623320 p.Leu531Met missense_variant 0.44 rifampicin
bedaquiline
lpqB 3623321 c.1590G>C synonymous_variant 0.43 rifampicin
bedaquiline
lpqB 3623324 c.1587C>G synonymous_variant 0.46 rifampicin
bedaquiline
lpqB 3623360 c.1551A>C synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3623363 c.1548T>C synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623366 c.1545T>C synonymous_variant 0.45 rifampicin
bedaquiline
lpqB 3623369 c.1542G>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623379 p.Ala511Ser missense_variant 0.5 rifampicin
bedaquiline
lpqB 3623393 c.1518A>C synonymous_variant 0.57 rifampicin
bedaquiline
lpqB 3623411 c.1500T>C synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3623423 c.1488C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623428 c.1483T>C synonymous_variant 0.38 rifampicin
bedaquiline
lpqB 3623639 c.1272A>G synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623648 c.1263A>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623654 p.Asp419Glu missense_variant 0.54 rifampicin
bedaquiline
lpqB 3623660 c.1251A>C synonymous_variant 0.55 rifampicin
bedaquiline
lpqB 3623666 c.1245A>C synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3623676 p.Val412Asn missense_variant 0.57 rifampicin
bedaquiline
lpqB 3623682 p.Thr410Ser missense_variant 0.55 rifampicin
bedaquiline
lpqB 3623684 c.1227T>C synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3623699 c.1212C>G synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3623702 c.1209G>C synonymous_variant 0.69 rifampicin
bedaquiline
lpqB 3623716 p.Ser399Ala missense_variant 0.71 rifampicin
bedaquiline
lpqB 3623731 p.Ser394Thr missense_variant 0.71 rifampicin
bedaquiline
lpqB 3623739 p.His391Arg missense_variant 0.73 rifampicin Uncertain significance
bedaquiline
lpqB 3623771 c.1140C>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3623782 p.Val377Ile missense_variant 0.66 rifampicin
bedaquiline
lpqB 3623788 c.1123T>C synonymous_variant 0.59 rifampicin
bedaquiline
lpqB 3623789 c.1122T>G synonymous_variant 0.59 rifampicin
bedaquiline
lpqB 3623800 p.Glu371Gln missense_variant 0.38 rifampicin
bedaquiline
lpqB 3623801 c.1110T>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623807 c.1104T>C synonymous_variant 0.35 rifampicin
bedaquiline
lpqB 3623816 p.Gly365Arg missense_variant 0.36 rifampicin
bedaquiline
lpqB 3624023 c.888G>C synonymous_variant 0.38 rifampicin
bedaquiline
lpqB 3624032 c.879T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 0.54 rifampicin
bedaquiline
lpqB 3624050 c.861C>G synonymous_variant 0.54 rifampicin
bedaquiline
lpqB 3624068 c.843G>C synonymous_variant 0.57 rifampicin
bedaquiline
lpqB 3624077 c.834G>T synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3624094 c.817A>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624098 c.811_813delTTGinsCTC synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624101 c.810C>G synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3624133 c.778A>C synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624140 c.771G>C synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624143 c.768T>C synonymous_variant 0.75 rifampicin
bedaquiline
lpqB 3624166 p.Met249Leu missense_variant 0.71 rifampicin
bedaquiline
lpqB 3624172 p.Val247Ile missense_variant 0.69 rifampicin
bedaquiline
lpqB 3624173 c.738A>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624176 c.735G>C synonymous_variant 0.69 rifampicin
bedaquiline
lpqB 3624194 c.717C>G synonymous_variant 0.65 rifampicin
bedaquiline
lpqB 3624200 c.711A>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624204 p.Ser236Asn missense_variant 0.67 rifampicin
bedaquiline
lpqB 3624209 c.702A>C synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624224 c.687T>G synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624242 c.669A>G synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3624245 c.664_666delCTAinsTTG synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3624254 c.657T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624263 c.648T>C synonymous_variant 0.55 rifampicin
bedaquiline
lpqB 3624266 c.645T>C synonymous_variant 0.55 rifampicin
bedaquiline
lpqB 3624272 c.639G>C synonymous_variant 0.57 rifampicin
bedaquiline
lpqB 3624276 p.Arg212His missense_variant 0.56 rifampicin
bedaquiline
lpqB 3624278 c.633G>C synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3624287 c.624G>C synonymous_variant 0.5 rifampicin
bedaquiline
lpqB 3624293 c.618A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624296 c.615T>G synonymous_variant 0.43 rifampicin
bedaquiline
lpqB 3624299 c.612G>C synonymous_variant 0.48 rifampicin
bedaquiline
lpqB 3624307 p.Leu202Met missense_variant 0.55 rifampicin
bedaquiline
lpqB 3624308 c.603A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624316 p.Val199Ile missense_variant 0.63 rifampicin
bedaquiline
lpqB 3624317 c.594C>G synonymous_variant 0.63 rifampicin
bedaquiline
lpqB 3624323 c.588G>C synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624328 p.Ala195Pro missense_variant 0.66 rifampicin
bedaquiline
lpqB 3624339 p.Arg191His missense_variant 0.65 rifampicin
bedaquiline
lpqB 3624341 c.570C>T synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624362 c.549G>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624365 c.546T>C synonymous_variant 0.72 rifampicin
bedaquiline
lpqB 3624371 c.540T>G synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624377 c.534C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 0.71 rifampicin
bedaquiline
lpqB 3624401 c.510C>T synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624416 c.495G>A synonymous_variant 0.71 rifampicin
bedaquiline
lpqB 3624422 c.489G>C synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624425 p.Glu162Ser missense_variant 0.73 rifampicin
bedaquiline
lpqB 3624428 c.483A>G synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624431 c.480C>T synonymous_variant 0.73 rifampicin
bedaquiline
lpqB 3624452 c.459T>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624464 c.447A>G synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624470 c.441T>C synonymous_variant 0.59 rifampicin
bedaquiline
lpqB 3624476 c.435C>G synonymous_variant 0.59 rifampicin
bedaquiline
lpqB 3624482 c.429T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624485 p.Asp142Gly missense_variant 0.52 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3624488 c.423C>G synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3624518 c.393T>C synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624527 p.Gln128Val missense_variant 0.61 rifampicin
bedaquiline
lpqB 3624530 c.381T>C synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624542 c.369G>A synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624545 c.366T>C synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624548 c.363G>C synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624551 c.360G>C synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624554 c.357G>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624557 c.354T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624560 c.351G>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624563 c.348C>G synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624569 c.342C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624572 c.339C>G synonymous_variant 0.75 rifampicin
bedaquiline
lpqB 3624575 c.336T>C synonymous_variant 0.75 rifampicin
bedaquiline
lpqB 3624581 c.330A>G synonymous_variant 0.76 rifampicin
bedaquiline
lpqB 3624594 p.Val106Ala missense_variant 0.79 rifampicin
bedaquiline
lpqB 3624603 p.Lys103Arg missense_variant 0.76 rifampicin
bedaquiline
lpqB 3624605 p.Glu102Asp missense_variant 0.79 rifampicin Uncertain significance
bedaquiline
lpqB 3624613 p.Ser100Gly missense_variant 0.8 rifampicin
bedaquiline
lpqB 3624614 c.297A>T synonymous_variant 0.8 rifampicin
bedaquiline
lpqB 3624623 c.288C>G synonymous_variant 0.79 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 0.76 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 0.76 rifampicin
bedaquiline
lpqB 3624650 c.261G>A synonymous_variant 0.76 rifampicin
bedaquiline
lpqB 3624656 c.255C>T synonymous_variant 0.79 rifampicin
bedaquiline
lpqB 3624671 c.240C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624680 c.231T>G synonymous_variant 0.84 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Gln missense_variant 0.86 rifampicin
bedaquiline
lpqB 3624695 c.216C>T synonymous_variant 0.88 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 0.86 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.85 rifampicin
bedaquiline
lpqB 3624731 c.180C>G synonymous_variant 0.85 rifampicin
bedaquiline
lpqB 3624734 c.177A>G synonymous_variant 0.82 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 0.8 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 0.76 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 0.68 rifampicin
bedaquiline
lpqB 3624785 c.126G>C synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624788 c.123A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3625054 c.-144C>G upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625066 c.-156G>C upstream_gene_variant 0.52 rifampicin
bedaquiline
lpqB 3625072 c.-162G>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3625095 p.Glu507Gln missense_variant 0.67 rifampicin
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.71 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3625135 c.1479A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.63 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.67 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.71 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.75 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrB 3625263 p.Tyr451His missense_variant 0.75 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>T upstream_gene_variant 0.81 rifampicin
bedaquiline
lpqB 3625273 c.-363C>G upstream_gene_variant 0.79 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 0.84 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.84 rifampicin
bedaquiline
lpqB 3625312 c.-402G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3625321 c.1293A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 0.7 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3625351 c.1263T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625357 c.-447T>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625375 c.-465A>G upstream_gene_variant 0.65 rifampicin
bedaquiline
lpqB 3625378 c.-468G>C upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625381 c.-471T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
lpqB 3625387 c.-477T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625396 c.-486G>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3625407 p.Gln403Glu missense_variant 0.53 rifampicin
bedaquiline
mtrB 3625408 c.1206G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625420 c.-510T>C upstream_gene_variant 0.51 rifampicin
bedaquiline
lpqB 3625423 c.-513G>C upstream_gene_variant 0.53 rifampicin
bedaquiline
lpqB 3625426 c.-516G>C upstream_gene_variant 0.53 rifampicin
bedaquiline
lpqB 3625431 c.-521T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
lpqB 3625438 c.-528T>C upstream_gene_variant 0.53 rifampicin
bedaquiline
lpqB 3625459 c.-549C>G upstream_gene_variant 0.44 rifampicin
bedaquiline
lpqB 3625462 c.-552G>C upstream_gene_variant 0.45 rifampicin
bedaquiline
lpqB 3625465 c.-555T>C upstream_gene_variant 0.48 rifampicin
bedaquiline
lpqB 3625471 c.-561C>G upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3625478 p.Asn379Ser missense_variant 0.43 rifampicin
bedaquiline
mtrB 3625480 p.Asn378Gln missense_variant 0.41 rifampicin
bedaquiline
lpqB 3625483 c.-573C>G upstream_gene_variant 0.43 rifampicin
bedaquiline
lpqB 3625486 c.-576G>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3625489 p.Thr375Ser missense_variant 0.43 rifampicin
bedaquiline
mtrB 3625497 c.1117T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625510 c.-600T>C upstream_gene_variant 0.65 rifampicin
bedaquiline
lpqB 3625513 c.-603G>C upstream_gene_variant 0.63 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
lpqB 3625528 c.-618G>C upstream_gene_variant 0.62 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.78 rifampicin
bedaquiline
lpqB 3625585 c.-675G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.78 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.78 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3625615 p.Arg333Ala missense_variant 0.79 rifampicin
bedaquiline
lpqB 3625627 c.-717C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625672 c.-762G>T upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.77 rifampicin
bedaquiline
lpqB 3625690 c.-780T>G upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.78 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625798 c.-888G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625803 c.-893C>T upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625840 c.-930A>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.58 rifampicin
bedaquiline
mtrB 3625867 c.747A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625888 c.-978G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625912 c.702G>C synonymous_variant 0.31 rifampicin
bedaquiline
mtrB 3625915 c.699G>C synonymous_variant 0.31 rifampicin
bedaquiline
mtrB 3626101 p.Gln171His missense_variant 0.37 rifampicin
bedaquiline
mtrB 3626125 c.489C>G synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3626131 c.483G>A synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3626142 p.Val158Ile missense_variant 0.41 rifampicin
bedaquiline
mtrB 3626149 c.465C>G synonymous_variant 0.4 rifampicin
bedaquiline
mtrB 3626157 p.Ala153Ser missense_variant 0.38 rifampicin
bedaquiline
mtrB 3626158 c.456C>T synonymous_variant 0.38 rifampicin
bedaquiline
mtrB 3626170 c.444T>C synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3626194 c.420T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626203 c.411G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626206 c.408T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626209 c.405T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626230 c.384T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626239 c.375T>C synonymous_variant 0.55 rifampicin
bedaquiline
mtrB 3626245 c.367_369delCTCinsTTG synonymous_variant 0.52 rifampicin
bedaquiline
mtrB 3626293 c.321G>C synonymous_variant 0.5 rifampicin
bedaquiline
mtrB 3626296 c.318T>G synonymous_variant 0.5 rifampicin
bedaquiline
mtrB 3626308 c.306T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626317 c.297A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626332 c.282T>C synonymous_variant 0.52 rifampicin
bedaquiline
mtrB 3626344 c.270G>C synonymous_variant 0.55 rifampicin
bedaquiline
mtrB 3626350 c.264C>G synonymous_variant 0.54 rifampicin
bedaquiline
mtrB 3626362 c.252A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626377 p.Asp79Glu missense_variant 0.6 rifampicin
bedaquiline
mtrB 3626383 c.231G>C synonymous_variant 0.59 rifampicin
bedaquiline
mtrB 3626386 c.228G>C synonymous_variant 0.59 rifampicin
bedaquiline
mtrB 3626390 p.Arg75Lys missense_variant 0.59 rifampicin
bedaquiline
mtrB 3626398 p.Ile72Val missense_variant 0.55 rifampicin
bedaquiline
mtrB 3626404 c.210C>G synonymous_variant 0.56 rifampicin
bedaquiline
mtrB 3626407 c.207C>G synonymous_variant 0.57 rifampicin
bedaquiline
mtrB 3626410 c.204T>C synonymous_variant 0.58 rifampicin
bedaquiline
mtrB 3626413 c.201T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626437 c.177T>C synonymous_variant 0.46 rifampicin
bedaquiline
mtrB 3626440 c.174C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626443 c.171T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626449 c.165G>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626455 c.159C>G synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626458 c.156C>G synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626461 c.153A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626467 c.147G>A synonymous_variant 1.0 rifampicin Not assoc w R
bedaquiline Not assoc w R - Interim
mtrB 3626470 c.144A>G synonymous_variant 0.4 rifampicin
bedaquiline
mtrB 3626473 c.141T>G synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3626684 c.-71G>A upstream_gene_variant 0.51 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrA 3626887 c.459_462delGTTG frameshift_variant 0.67 rifampicin
bedaquiline
mtrA 3626894 c.455_456insTTTC frameshift_variant 0.65 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626927 c.-314G>C upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 0.79 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.81 rifampicin
bedaquiline
mtrB 3626992 c.-379C>T upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3626999 c.-386G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627011 c.-398T>C upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627119 c.-506T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627131 c.-518C>G upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627139 c.-526T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3627196 c.-583C>T upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3627203 c.-590C>A upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrA 3627208 c.142C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3627227 c.-614T>G upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627269 c.-656G>C upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3627301 c.-688T>C upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrB 3627320 c.-707C>G upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.43 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.29 rifampicin
bedaquiline
fbiA 3640849 p.Glu103Gln missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3640854 c.-681C>G upstream_gene_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3640857 c.-678G>T upstream_gene_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3640866 c.-669T>C upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fbiB 3640899 c.-636G>C upstream_gene_variant 0.56 pretomanid
delamanid
clofazimine
fbiA 3640900 p.Gln120Asn missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiB 3640914 c.-621C>G upstream_gene_variant 0.58 pretomanid
delamanid
clofazimine
fbiA 3640930 p.Glu130Thr missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiB 3640935 c.-600C>G upstream_gene_variant 0.57 pretomanid
delamanid
clofazimine
fbiB 3640938 c.-597A>G upstream_gene_variant 0.58 pretomanid
delamanid
clofazimine
fbiB 3640944 c.-591T>C upstream_gene_variant 0.59 pretomanid
delamanid
clofazimine
fbiB 3640953 c.-582A>G upstream_gene_variant 0.64 pretomanid
delamanid
clofazimine
fbiA 3640958 p.Gly139Asp missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiB 3640962 c.-573C>G upstream_gene_variant 0.66 pretomanid
delamanid
clofazimine
fbiB 3640965 c.-570C>G upstream_gene_variant 0.66 pretomanid
delamanid
clofazimine
fbiB 3640966 c.-569T>C upstream_gene_variant 0.66 pretomanid
delamanid
clofazimine
fbiA 3640974 c.432T>G synonymous_variant 0.62 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiB 3640989 c.-546T>C upstream_gene_variant 0.63 pretomanid
delamanid
clofazimine
fbiB 3640995 c.-540A>G upstream_gene_variant 0.6 pretomanid
delamanid
clofazimine
fbiB 3641001 c.-534T>C upstream_gene_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3641004 c.-531A>G upstream_gene_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3641016 c.-519C>T upstream_gene_variant 0.57 pretomanid
delamanid
clofazimine
fbiA 3641021 p.Val160Asp missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3641073 c.-462T>G upstream_gene_variant 0.56 pretomanid
delamanid
clofazimine
fbiB 3641085 c.-450G>C upstream_gene_variant 0.56 pretomanid
delamanid
clofazimine
fbiA 3641170 p.Met210Leu missense_variant 0.69 pretomanid
delamanid
clofazimine
fbiB 3641178 c.-357G>C upstream_gene_variant 0.65 pretomanid
delamanid
clofazimine
fbiB 3641184 c.-351T>C upstream_gene_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3641187 c.-348T>C upstream_gene_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3641196 c.-339C>G upstream_gene_variant 0.43 pretomanid
delamanid
clofazimine
fbiA 3641200 p.Ile220Val missense_variant 0.42 pretomanid
delamanid
clofazimine
fbiA 3641260 p.Ile240Val missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3641271 c.-264C>T upstream_gene_variant 0.3 pretomanid
delamanid
clofazimine
fbiA 3641288 p.Glu249Gly missense_variant 0.29 pretomanid
delamanid
clofazimine
alr 3840344 c.1077A>G synonymous_variant 0.54 cycloserine
alr 3840350 c.1071G>C synonymous_variant 0.55 cycloserine
alr 3840353 c.1068T>C synonymous_variant 0.54 cycloserine
alr 3840356 p.Leu355Ala missense_variant 0.54 cycloserine
alr 3840380 p.Met347Val missense_variant 0.51 cycloserine
alr 3840407 p.Val338Ala missense_variant 0.41 cycloserine
alr 3840410 c.1011T>C synonymous_variant 0.42 cycloserine
alr 3840416 p.Cys335Arg missense_variant 0.43 cycloserine
alr 3840419 c.1002A>G synonymous_variant 0.44 cycloserine
alr 3840422 c.999A>G synonymous_variant 0.45 cycloserine
alr 3840461 c.960G>C synonymous_variant 0.49 cycloserine
alr 3840476 c.945A>G synonymous_variant 0.42 cycloserine
alr 3840482 c.939T>C synonymous_variant 0.42 cycloserine
alr 3840500 c.921G>T synonymous_variant 0.37 cycloserine
alr 3840503 p.Asn306Thr missense_variant 0.37 cycloserine
alr 3840515 p.Pro302Ser missense_variant 0.37 cycloserine
alr 3840522 p.Ile300Thr missense_variant 0.34 cycloserine
alr 3840527 c.894A>C synonymous_variant 0.31 cycloserine
alr 3840536 c.885T>C synonymous_variant 0.33 cycloserine
alr 3840539 c.882G>C synonymous_variant 0.32 cycloserine
alr 3840547 p.Gly292Ser missense_variant 0.31 cycloserine
alr 3840560 p.Ile287Val missense_variant 0.41 cycloserine
alr 3840566 c.855A>G synonymous_variant 0.42 cycloserine
alr 3840569 c.852G>A synonymous_variant 0.42 cycloserine
alr 3840578 c.843T>G synonymous_variant 0.43 cycloserine
alr 3840584 c.837T>C synonymous_variant 0.41 cycloserine
alr 3840593 c.828C>G synonymous_variant 0.31 cycloserine
alr 3840965 c.456G>C synonymous_variant 0.53 cycloserine
alr 3840974 c.447C>G synonymous_variant 0.53 cycloserine
alr 3840980 c.441G>C synonymous_variant 0.53 cycloserine
alr 3840983 c.438C>G synonymous_variant 0.51 cycloserine
alr 3840989 c.432G>C synonymous_variant 0.55 cycloserine
alr 3840994 p.His143Asp missense_variant 0.51 cycloserine
alr 3840995 c.424_426delTTGinsCTC synonymous_variant 0.51 cycloserine
alr 3841001 c.420A>G synonymous_variant 0.53 cycloserine
alr 3841010 c.411A>G synonymous_variant 0.59 cycloserine
alr 3841017 p.Leu135Ala missense_variant 0.59 cycloserine
alr 3841025 c.396G>A synonymous_variant 0.62 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.68 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.7 cycloserine
alr 3841037 c.384G>C synonymous_variant 0.7 cycloserine
alr 3841046 c.375G>C synonymous_variant 0.68 cycloserine
alr 3841055 c.366C>G synonymous_variant 0.62 cycloserine
alr 3841058 c.363G>C synonymous_variant 0.6 cycloserine
alr 3841073 c.348C>G synonymous_variant 0.56 cycloserine
alr 3841079 c.342T>C synonymous_variant 0.48 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 0.45 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.52 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.51 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.59 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.62 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.59 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877572 c.936G>C synonymous_variant 0.66 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.82 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.75 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.75 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.77 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.8 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877821 c.687C>G synonymous_variant 0.76 rifampicin
rpoA 3877830 c.678C>T synonymous_variant 0.77 rifampicin
rpoA 3877839 c.669G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.77 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.73 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.75 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.75 rifampicin
rpoA 3877931 p.Ile193Val missense_variant 0.76 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.81 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.81 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.82 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.84 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.84 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.85 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.84 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.84 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.86 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.86 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.86 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.85 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.85 rifampicin
rpoA 3878143 p.Gly122Ala missense_variant 0.83 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.81 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.79 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878256 c.252G>C synonymous_variant 0.81 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.83 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.84 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.86 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.85 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.86 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.85 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.84 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 0.82 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.78 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.74 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.73 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.73 rifampicin
rpoA 3878458 p.Asn17Thr missense_variant 0.69 rifampicin
rpoA 3878468 p.Leu14Val missense_variant 0.65 rifampicin Uncertain significance
rpoA 3878472 p.Asp12Glu missense_variant 0.64 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.63 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.63 rifampicin
rpoA 3878695 c.-188C>G upstream_gene_variant 0.81 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.85 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.83 rifampicin
rpoA 3878722 c.-215C>G upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3878725 c.-218A>G upstream_gene_variant 0.8 rifampicin
rpoA 3878731 c.-224C>T upstream_gene_variant 0.8 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.81 rifampicin
rpoA 3878749 c.-242G>C upstream_gene_variant 0.82 rifampicin
rpoA 3878752 c.-245G>A upstream_gene_variant 0.81 rifampicin
rpoA 3878758 c.-251G>C upstream_gene_variant 0.82 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.82 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878791 c.-284C>T upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.85 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 0.86 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.87 rifampicin
rpoA 3878824 c.-319_-317delACGinsTCC upstream_gene_variant 0.88 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.87 rifampicin
rpoA 3878836 c.-329G>C upstream_gene_variant 0.88 rifampicin Uncertain significance
rpoA 3878853 c.-346G>A upstream_gene_variant 0.87 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 0.89 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 0.88 rifampicin
rpoA 3878908 c.-402_-401delACinsCG upstream_gene_variant 0.84 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.84 rifampicin
rpoA 3878924 c.-417G>C upstream_gene_variant 0.86 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.85 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 0.85 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.81 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.8 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.8 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.8 rifampicin
rpoA 3879037 c.-530G>T upstream_gene_variant 0.82 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.84 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.84 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.83 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.84 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.82 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 0.82 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.83 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.85 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.83 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.78 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.74 rifampicin
rpoA 3879199 c.-692C>G upstream_gene_variant 0.74 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.72 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.71 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.71 rifampicin
ddn 3986633 c.-211C>G upstream_gene_variant 0.66 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.67 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.67 pretomanid
delamanid
ddn 3986660 c.-184C>T upstream_gene_variant 0.66 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.66 pretomanid
delamanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.55 pretomanid
delamanid
ddn 3986693 c.-151C>G upstream_gene_variant 0.56 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.55 pretomanid
delamanid
clpC1 4038197 c.2508A>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4038200 c.2505T>G synonymous_variant 0.31 pyrazinamide
clpC1 4038212 c.2493T>C synonymous_variant 0.49 pyrazinamide
clpC1 4038233 c.2472C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038239 c.2466T>A synonymous_variant 0.56 pyrazinamide
clpC1 4038266 c.2439C>G synonymous_variant 0.68 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.68 pyrazinamide
clpC1 4038272 p.Gly811Ser missense_variant 0.68 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038308 p.Val799Ile missense_variant 0.73 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.69 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.73 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.69 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.71 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 0.69 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.7 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038454 p.Leu751Met missense_variant 0.71 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.71 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038482 c.2223G>A synonymous_variant 0.8 pyrazinamide
clpC1 4038485 c.2220C>G synonymous_variant 0.8 pyrazinamide
clpC1 4038488 c.2217C>G synonymous_variant 0.79 pyrazinamide
clpC1 4038498 p.Ser736Ala missense_variant 0.79 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.76 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.77 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.77 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.76 pyrazinamide
clpC1 4038659 p.Ser682Thr missense_variant 0.76 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.73 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.7 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038848 c.1857C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4038899 c.1806C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.83 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038911 c.1794G>A synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.82 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.84 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039037 c.1668T>G synonymous_variant 0.73 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.77 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.78 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.78 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 0.7 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>G synonymous_variant 0.73 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.77 pyrazinamide
clpC1 4039348 c.1357C>A synonymous_variant 0.79 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.79 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.88 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.74 pyrazinamide
clpC1 4039448 c.1257A>C synonymous_variant 0.74 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 0.65 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.69 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.67 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039601 c.1104G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.68 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.81 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040048 c.657C>G synonymous_variant 0.81 pyrazinamide
clpC1 4040057 c.648C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040066 c.639G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040078 c.627G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.78 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040144 c.561G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.84 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040195 c.510G>T synonymous_variant 0.87 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.81 pyrazinamide
clpC1 4040213 c.492T>G synonymous_variant 0.79 pyrazinamide
clpC1 4040225 c.480A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040228 c.477G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040234 c.471C>T synonymous_variant 0.81 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.81 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.8 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.83 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040327 c.378G>A synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040354 c.351A>G synonymous_variant 0.78 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.78 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.78 pyrazinamide
clpC1 4040377 c.328C>T synonymous_variant 0.79 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.78 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.78 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.78 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.77 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.73 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 0.66 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>G synonymous_variant 0.68 pyrazinamide
clpC1 4040517 p.Val63Ala missense_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 0.63 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.64 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040546 c.159G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.53 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.43 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.43 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4040579 c.126A>G synonymous_variant 0.43 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.41 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.4 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.39 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.43 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.43 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.47 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.31 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.26 pyrazinamide
panD 4043865 p.Gly139Arg missense_variant 0.53 pyrazinamide Uncertain significance
panD 4043876 p.Leu136Ile missense_variant 0.4 pyrazinamide
panD 4044057 c.225C>A synonymous_variant 0.27 pyrazinamide
panD 4044063 c.219T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
panD 4044072 c.210C>A synonymous_variant 0.34 pyrazinamide
panD 4044075 c.207T>A synonymous_variant 0.34 pyrazinamide
panD 4044081 c.201T>C synonymous_variant 0.42 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 0.46 pyrazinamide
panD 4044090 c.192C>G synonymous_variant 0.47 pyrazinamide
panD 4044093 c.189A>G synonymous_variant 0.47 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 0.54 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.54 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.55 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
panD 4044141 c.141C>G synonymous_variant 0.6 pyrazinamide
panD 4044150 c.132A>G synonymous_variant 0.57 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
panD 4044162 c.120A>G synonymous_variant 0.6 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.6 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 0.62 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.62 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.6 pyrazinamide
panD 4044201 c.81C>G synonymous_variant 0.62 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.6 pyrazinamide
panD 4044213 c.69C>G synonymous_variant 0.59 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 0.54 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.54 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 0.52 pyrazinamide
panD 4044287 c.-6A>G upstream_gene_variant 0.38 pyrazinamide
panD 4044671 c.-390G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.48 pyrazinamide
panD 4044740 c.-459C>T upstream_gene_variant 0.55 pyrazinamide
panD 4044746 c.-467_-465delGTGinsATC upstream_gene_variant 0.47 pyrazinamide
panD 4044749 c.-468G>A upstream_gene_variant 0.45 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.45 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 0.45 pyrazinamide
panD 4044758 c.-477C>T upstream_gene_variant 0.45 pyrazinamide
panD 4044773 c.-492G>C upstream_gene_variant 0.43 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.41 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 0.41 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.39 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.38 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.46 pyrazinamide
panD 4044820 c.-539C>G upstream_gene_variant 0.39 pyrazinamide
panD 4044822 c.-541G>C upstream_gene_variant 0.43 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.42 pyrazinamide
glpK 4138268 c.1488T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138273 p.Glu495Gln missense_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138286 c.1470G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138289 c.1467G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138292 c.1464A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138310 c.1446A>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138322 c.1434G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138328 p.Asp476Glu missense_variant 0.76 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138338 p.Ala473Asp missense_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138340 c.1416G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138352 c.1404C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138355 c.1401G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138360 c.1396T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138361 c.1395C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138364 c.1392G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138376 p.Val460Ala missense_variant 0.72 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138382 c.1374A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138385 c.1371A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138406 c.1350G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138418 c.1338T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138429 c.1327T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138442 c.1314C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138472 c.1284G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138478 c.1278T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138489 c.1267T>C synonymous_variant 0.69 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138490 p.Val422Ile missense_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138495 p.Gln421Glu missense_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138496 c.1260G>A synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138502 c.1254T>G synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138511 c.1245C>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138517 p.Glu413Lys missense_variant 0.67 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138523 c.1233C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138535 c.1221T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138583 c.1173G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138610 c.1146C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138646 c.1110G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138654 c.1102C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138681 p.Met359Val missense_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138714 p.Ala348Ser missense_variant 0.69 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.997_999delCTAinsTTG synonymous_variant 0.68 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138781 c.975G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138787 c.969C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138790 c.966G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138799 c.957T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138808 c.948G>T synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138814 c.942A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 c.939T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138819 c.935_936delAC frameshift_variant 0.6 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138823 c.932_933insCG frameshift_variant 0.58 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138829 c.927A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138832 c.924C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138838 c.918G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138847 c.909A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138859 p.Asn299Gln missense_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138865 c.891A>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138875 p.Thr294Lys missense_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138877 c.879A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138880 c.876T>G synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138889 c.867G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139090 c.666G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139104 c.652T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139132 c.624A>G synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139135 p.Asp207Asn missense_variant 0.52 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139143 c.613T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139147 c.609C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139165 c.591A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139177 c.579T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139189 c.567G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139195 c.561G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139204 c.552G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139312 c.444T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139315 c.441C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139318 c.438T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139321 c.435T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139324 c.432A>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139333 c.423G>A synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139339 c.417G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139357 p.Asn133Glu missense_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139360 c.396A>C synonymous_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139363 c.393T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139366 c.390T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139375 p.Asp127Gln missense_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139381 c.375G>A synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139387 c.369G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139393 c.363C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139399 c.357C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139408 c.348T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139417 c.339A>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139420 c.336T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
embC 4238921 c.-942G>C upstream_gene_variant 0.43 ethambutol
embC 4238923 c.-940C>T upstream_gene_variant 0.4 ethambutol
embC 4238928 c.-935C>G upstream_gene_variant 0.38 ethambutol
embC 4238931 c.-932G>A upstream_gene_variant 0.38 ethambutol Uncertain significance
embC 4238943 c.-920G>A upstream_gene_variant 0.35 ethambutol Uncertain significance
embC 4238947 c.-916C>G upstream_gene_variant 0.35 ethambutol
embC 4238969 c.-894A>G upstream_gene_variant 0.3 ethambutol
embC 4238975 c.-888A>C upstream_gene_variant 0.38 ethambutol
embC 4238986 c.-877_-876delCAinsTG upstream_gene_variant 0.46 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 0.61 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 0.59 ethambutol
embC 4239023 c.-840C>A upstream_gene_variant 0.55 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 0.52 ethambutol Uncertain significance
embC 4239053 c.-810G>C upstream_gene_variant 0.47 ethambutol
embC 4239057 c.-806A>G upstream_gene_variant 0.46 ethambutol
embC 4239066 c.-797_-795delCGAinsGGG upstream_gene_variant 0.44 ethambutol
embC 4239071 c.-792A>G upstream_gene_variant 0.43 ethambutol Uncertain significance
embC 4239074 c.-789G>C upstream_gene_variant 0.44 ethambutol
embC 4239076 c.-787C>T upstream_gene_variant 0.44 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 0.44 ethambutol
embC 4239083 c.-780C>G upstream_gene_variant 0.46 ethambutol
embC 4239092 c.-771G>T upstream_gene_variant 0.46 ethambutol
embC 4239101 c.-762C>G upstream_gene_variant 0.47 ethambutol Uncertain significance
embC 4239108 c.-755G>T upstream_gene_variant 0.47 ethambutol
embC 4239111 c.-752G>A upstream_gene_variant 0.49 ethambutol
embC 4239125 c.-738C>A upstream_gene_variant 0.47 ethambutol
embC 4239593 c.-270G>A upstream_gene_variant 1.0 ethambutol Not assoc w R
embC 4240175 c.313T>C synonymous_variant 0.44 ethambutol
embC 4240178 c.316_318delTTGinsCTC synonymous_variant 0.42 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.44 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embC 4240216 c.354T>C synonymous_variant 0.66 ethambutol
embC 4240228 c.366G>C synonymous_variant 0.68 ethambutol
embC 4240229 p.Leu123Ile missense_variant 0.67 ethambutol
embC 4240234 c.372A>G synonymous_variant 0.67 ethambutol
embC 4240237 c.375G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embC 4240258 c.396T>G synonymous_variant 0.62 ethambutol
embC 4240261 c.399G>C synonymous_variant 0.62 ethambutol
embC 4240264 c.402G>C synonymous_variant 0.64 ethambutol
embC 4240267 c.405T>C synonymous_variant 0.64 ethambutol
embC 4240270 c.408T>C synonymous_variant 0.66 ethambutol
embC 4240277 p.Leu139Val missense_variant 0.66 ethambutol
embC 4240292 c.430C>T synonymous_variant 0.64 ethambutol
embC 4240297 c.435T>C synonymous_variant 0.66 ethambutol
embC 4240313 p.Thr151Ala missense_variant 0.67 ethambutol
embC 4240318 c.456T>C synonymous_variant 0.61 ethambutol
embC 4240330 c.468A>C synonymous_variant 0.53 ethambutol
embC 4240610 p.Ile250Val missense_variant 0.39 ethambutol
embC 4240615 c.753G>C synonymous_variant 0.48 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.48 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.52 ethambutol
embC 4240660 c.798C>G synonymous_variant 0.57 ethambutol
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 0.57 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.56 ethambutol
embC 4240690 c.828G>C synonymous_variant 0.56 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.57 ethambutol
embC 4240702 c.840G>C synonymous_variant 0.63 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.66 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.67 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.67 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.66 ethambutol
embC 4240807 c.945C>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embC 4240811 p.Phe317Leu missense_variant 0.66 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.66 ethambutol
embC 4240831 c.969T>C synonymous_variant 0.68 ethambutol
embC 4240843 c.981C>T synonymous_variant 0.68 ethambutol
embC 4240859 c.997C>T synonymous_variant 0.64 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.63 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.65 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.6 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.6 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.62 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.55 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.55 ethambutol
embC 4240912 c.1050G>C synonymous_variant 0.58 ethambutol
embC 4240918 c.1056G>C synonymous_variant 0.55 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.55 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.57 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.58 ethambutol
embC 4240945 c.1083T>C synonymous_variant 0.58 ethambutol
embC 4240948 c.1086G>A synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embC 4240954 p.Ile364Met missense_variant 0.6 ethambutol
embC 4240960 c.1098G>C synonymous_variant 0.58 ethambutol
embC 4240966 c.1104G>T synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embC 4240967 p.His369Asn missense_variant 0.48 ethambutol
embC 4240980 p.Thr373Lys missense_variant 0.55 ethambutol
embC 4240983 p.Ser374Asn missense_variant 0.55 ethambutol
embC 4240985 c.1123C>A synonymous_variant 0.55 ethambutol
embC 4240990 c.1128A>C synonymous_variant 0.62 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.67 ethambutol
embC 4241013 p.Met384Thr missense_variant 0.74 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.75 ethambutol
embC 4241023 c.1161T>C synonymous_variant 0.77 ethambutol
embC 4241026 c.1164C>G synonymous_variant 0.78 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.75 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.78 ethambutol
embC 4241053 c.1191G>A synonymous_variant 0.77 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.78 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.76 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.78 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.79 ethambutol
embC 4241125 c.1263G>C synonymous_variant 0.78 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.74 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.75 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embC 4241185 c.1323G>C synonymous_variant 0.73 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.68 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.6 ethambutol
embC 4241233 c.1371G>C synonymous_variant 0.59 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.46 ethambutol
embC 4241452 c.1590G>C synonymous_variant 0.46 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.46 ethambutol
embC 4241458 c.1596_1599delCCGCinsGCGG synonymous_variant 0.5 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.37 ethambutol
embC 4241480 p.Leu540Val missense_variant 0.38 ethambutol
embC 4241483 p.Val541Leu missense_variant 0.35 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.35 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.32 ethambutol
embC 4241498 p.Val546Ile missense_variant 0.32 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.33 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.51 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>A synonymous_variant 0.55 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.5 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241542 c.1680C>G synonymous_variant 0.5 ethambutol
embC 4241545 c.1683T>G synonymous_variant 0.48 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.48 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.48 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.52 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.5 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.41 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.47 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.48 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.5 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.5 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.56 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.54 ethambutol
embC 4241638 c.1776G>C synonymous_variant 0.52 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.5 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.49 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>T synonymous_variant 0.49 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.43 ethambutol
embC 4241671 c.1809T>G synonymous_variant 0.46 ethambutol
embC 4241689 c.1827G>C synonymous_variant 0.46 ethambutol
embC 4241690 p.Gly610Ser missense_variant 0.46 ethambutol Uncertain significance
embC 4241694 p.Ala611Val missense_variant 0.46 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.49 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.45 ethambutol
embC 4241719 c.1857G>A synonymous_variant 0.45 ethambutol Not assoc w R - Interim
embC 4241722 c.1860C>G synonymous_variant 0.45 ethambutol
embC 4241737 c.1875G>C synonymous_variant 0.29 ethambutol
embC 4241755 c.1893C>T synonymous_variant 0.28 ethambutol
embC 4242121 c.2259A>G synonymous_variant 0.31 ethambutol
embC 4242127 c.2265G>C synonymous_variant 0.34 ethambutol
embC 4242128 p.Leu756Met missense_variant 0.34 ethambutol
embC 4242138 p.Leu759Gln missense_variant 0.34 ethambutol
embC 4242149 p.Ala763Pro missense_variant 0.37 ethambutol
embC 4242154 c.2292C>G synonymous_variant 0.37 ethambutol
embC 4242170 p.Thr770Ser missense_variant 0.37 ethambutol
embC 4242174 p.Ala771Val missense_variant 0.37 ethambutol
embC 4242179 p.Leu773Val missense_variant 0.37 ethambutol
embC 4242182 p.Ala774Arg missense_variant 0.37 ethambutol
embC 4242190 c.2328C>G synonymous_variant 0.38 ethambutol
embC 4242191 c.2329C>T synonymous_variant 0.38 ethambutol
embC 4242199 c.2337C>G synonymous_variant 0.45 ethambutol
embC 4242208 c.2346T>G synonymous_variant 0.45 ethambutol
embC 4242220 c.2358A>G synonymous_variant 0.5 ethambutol
embC 4242245 p.Thr795Arg missense_variant 0.57 ethambutol
embC 4242643 c.2781C>T synonymous_variant 0.81 ethambutol Not assoc w R
embC 4242710 p.Gln950Glu missense_variant 0.54 ethambutol
embC 4242715 c.2853T>C synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embA 4242718 c.-515G>C upstream_gene_variant 0.54 ethambutol
embA 4242739 c.-494C>G upstream_gene_variant 0.62 ethambutol
embA 4242742 c.-491C>G upstream_gene_variant 0.62 ethambutol
embA 4242745 c.-488A>C upstream_gene_variant 0.67 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.67 ethambutol
embC 4242762 p.Arg967Gln missense_variant 0.64 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.65 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.66 ethambutol
embC 4242791 p.Ala977Ser missense_variant 0.73 ethambutol
embA 4242796 c.-437G>C upstream_gene_variant 0.71 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.73 ethambutol
embA 4242826 c.-407G>C upstream_gene_variant 0.67 ethambutol
embA 4242829 c.-404G>C upstream_gene_variant 0.65 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.65 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.66 ethambutol
embA 4242847 c.-386C>T upstream_gene_variant 0.65 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.67 ethambutol
embA 4242880 c.-353A>C upstream_gene_variant 0.61 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embA 4242892 c.-341G>C upstream_gene_variant 0.57 ethambutol
embA 4242901 c.-332G>C upstream_gene_variant 0.53 ethambutol
embA 4243848 p.Val206Met missense_variant 1.0 ethambutol Not assoc w R
embA 4244336 c.1104C>T synonymous_variant 0.25 ethambutol
embA 4244372 c.1140T>G synonymous_variant 0.36 ethambutol
embA 4244381 c.1149G>A synonymous_variant 0.36 ethambutol
embA 4244393 c.1161G>C synonymous_variant 0.35 ethambutol
embA 4244396 c.1164T>C synonymous_variant 0.35 ethambutol
embA 4244415 c.1183_1185delTTGinsCTC synonymous_variant 0.37 ethambutol
embA 4244420 c.1188G>C synonymous_variant 0.35 ethambutol Not assoc w R
embA 4244426 c.1194G>C synonymous_variant 0.37 ethambutol
embA 4244427 p.Ser399Ala missense_variant 0.37 ethambutol
embA 4244438 c.1206C>G synonymous_variant 0.35 ethambutol
embA 4244633 c.1401C>G synonymous_variant 0.39 ethambutol
embA 4244642 c.1410G>C synonymous_variant 0.41 ethambutol
embA 4244645 c.1413T>C synonymous_variant 0.41 ethambutol
embA 4244648 c.1416G>C synonymous_variant 0.41 ethambutol
embA 4244649 p.Asp473Ser missense_variant 0.41 ethambutol
embA 4244666 c.1434G>C synonymous_variant 0.43 ethambutol
embA 4244669 c.1437G>C synonymous_variant 0.44 ethambutol
embA 4244672 c.1440C>G synonymous_variant 0.46 ethambutol
embA 4244681 c.1449A>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4244702 c.1470C>G synonymous_variant 0.54 ethambutol
embA 4244708 c.1476C>G synonymous_variant 0.54 ethambutol
embA 4244726 p.Asp498Glu missense_variant 0.56 ethambutol
embA 4244728 p.Phe499Trp missense_variant 0.6 ethambutol
embA 4244747 c.1515T>C synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embA 4244756 c.1524G>A synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embA 4244764 p.Val511Ala missense_variant 0.59 ethambutol
embA 4244771 c.1539G>C synonymous_variant 0.58 ethambutol
embA 4244778 p.Ser516Ala missense_variant 0.61 ethambutol
embA 4244783 c.1551C>G synonymous_variant 0.64 ethambutol
embA 4244792 c.1560G>C synonymous_variant 0.56 ethambutol
embA 4244802 p.Leu524Met missense_variant 0.5 ethambutol
embA 4244805 c.1573C>T synonymous_variant 0.44 ethambutol
embA 4244807 p.Phe526Leu missense_variant 0.52 ethambutol
embA 4244823 p.Val531Met missense_variant 0.59 ethambutol
embA 4244829 p.Phe533Val missense_variant 0.62 ethambutol
embA 4244843 c.1611G>C synonymous_variant 0.65 ethambutol
embA 4244850 p.Arg540Ala missense_variant 0.63 ethambutol
embA 4244856 p.Ala542Pro missense_variant 0.67 ethambutol
embA 4244861 c.1629G>C synonymous_variant 0.67 ethambutol
embA 4244879 c.1647C>G synonymous_variant 0.56 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.52 ethambutol
embA 4244886 c.1654C>T synonymous_variant 0.5 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.48 ethambutol
embA 4244904 p.Val558Ile missense_variant 0.47 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.45 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.47 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.47 ethambutol
embA 4244960 c.1728A>G synonymous_variant 0.44 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.3 ethambutol
embA 4245050 c.1818C>T synonymous_variant 0.54 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.57 ethambutol
embA 4245074 c.1842G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embA 4245078 p.Trp616Val missense_variant 0.6 ethambutol
embA 4245083 c.1851A>G synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embA 4245089 c.1857G>C synonymous_variant 0.62 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.62 ethambutol
embA 4245108 p.Tyr626Gly missense_variant 0.62 ethambutol
embA 4245114 p.Gly628Ser missense_variant 0.64 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.72 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.73 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.71 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.71 ethambutol
embA 4245183 c.1951C>T synonymous_variant 0.7 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.74 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.71 ethambutol
embA 4245206 c.1974A>C synonymous_variant 0.67 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.67 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.63 ethambutol
embA 4245222 p.Tyr664Gln missense_variant 0.57 ethambutol
embA 4245233 c.2001G>C synonymous_variant 0.58 ethambutol
embA 4245245 c.2013C>G synonymous_variant 0.62 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.61 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.62 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.49 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.4 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.39 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.38 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.39 ethambutol
embA 4245299 c.2067A>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embA 4245308 c.2076G>C synonymous_variant 0.41 ethambutol
embA 4245315 p.Val695Met missense_variant 0.42 ethambutol Uncertain significance
embA 4245328 p.Ala699Val missense_variant 0.36 ethambutol
embA 4245335 c.2103A>G synonymous_variant 0.36 ethambutol
embA 4245340 p.Gly703Ala missense_variant 0.36 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.36 ethambutol
embA 4245348 p.Ala706Thr missense_variant 0.35 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.36 ethambutol
embA 4245362 c.2130G>C synonymous_variant 0.38 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.4 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 0.36 ethambutol
embA 4245626 c.2394G>A synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4245644 c.-870C>G upstream_gene_variant 0.4 ethambutol
embA 4245650 p.Ile806Met missense_variant 0.4 ethambutol
embA 4245652 p.Thr807Ser missense_variant 0.4 ethambutol
embA 4245656 c.2424C>T synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embB 4245668 c.-846C>G upstream_gene_variant 0.52 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.55 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.55 ethambutol
embA 4245688 p.Val819Ala missense_variant 0.53 ethambutol
embB 4245692 c.-822G>T upstream_gene_variant 0.55 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.55 ethambutol
embA 4245701 c.2469G>T synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embA 4245969 p.Pro913Ser missense_variant 1.0 ethambutol Not assoc w R
embA 4246278 p.Ala1016Ser missense_variant 0.54 ethambutol Uncertain significance
embA 4246290 p.Leu1020Gly missense_variant 0.47 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 0.49 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.5 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.5 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 0.49 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.5 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.51 ethambutol
embA 4246383 p.Tyr1051His missense_variant 0.51 ethambutol
embB 4246403 c.-111G>C upstream_gene_variant 0.47 ethambutol
embB 4247320 c.807T>C synonymous_variant 0.38 ethambutol
embB 4247326 c.813A>C synonymous_variant 0.4 ethambutol
embB 4247328 p.Ser272Asn missense_variant 0.4 ethambutol Uncertain significance
embB 4247338 c.825C>G synonymous_variant 0.46 ethambutol
embB 4247348 p.Thr279Ala missense_variant 0.49 ethambutol
embB 4247357 p.Val282Thr missense_variant 0.48 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.59 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.65 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.67 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.71 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.71 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.74 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4247464 c.951C>G synonymous_variant 0.8 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.8 ethambutol
embB 4247485 c.972C>G synonymous_variant 0.8 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.81 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.82 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.74 ethambutol
embB 4247544 p.Ser344Thr missense_variant 0.74 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.71 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.51 ethambutol
embB 4247567 c.1054C>T synonymous_variant 0.5 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.5 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.51 ethambutol
embB 4247606 c.1093C>T synonymous_variant 0.39 ethambutol
embB 4247614 c.1101T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4247623 c.1110G>C synonymous_variant 0.29 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
embB 4247683 c.1170C>G synonymous_variant 0.36 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.37 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.32 ethambutol
embB 4247753 p.Val414Ile missense_variant 0.43 ethambutol Uncertain significance
embB 4247761 c.1248T>C synonymous_variant 0.54 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.6 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.59 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.6 ethambutol
embB 4247800 c.1287A>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embB 4247803 c.1290G>C synonymous_variant 0.56 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.55 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.53 ethambutol Uncertain significance
embB 4247827 c.1314C>G synonymous_variant 0.54 ethambutol
embB 4247830 c.1317A>C synonymous_variant 0.54 ethambutol
embB 4247836 c.1323A>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.55 ethambutol Not assoc w R - Interim
embB 4247842 c.1329T>C synonymous_variant 0.57 ethambutol
embB 4247845 c.1332G>C synonymous_variant 0.6 ethambutol
embB 4247857 c.1344C>G synonymous_variant 0.64 ethambutol
embB 4247869 c.1356G>C synonymous_variant 0.63 ethambutol
embB 4247878 c.1365G>C synonymous_variant 0.62 ethambutol
embB 4247879 p.Val456Ile missense_variant 0.62 ethambutol
embB 4247890 c.1377C>G synonymous_variant 0.67 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.69 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.63 ethambutol
embB 4247917 c.1404C>G synonymous_variant 0.58 ethambutol
embB 4247920 c.1407T>C synonymous_variant 0.53 ethambutol
embB 4247923 c.1410T>C synonymous_variant 0.5 ethambutol
embB 4247926 c.1413C>G synonymous_variant 0.52 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.57 ethambutol
embB 4247944 c.1431G>C synonymous_variant 0.55 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.61 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.66 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4247972 p.Thr487Ala missense_variant 0.7 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.74 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.74 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.73 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.72 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.76 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.77 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.79 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.82 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.81 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.8 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.82 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.81 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.82 ethambutol
embB 4248158 p.Cys549Ser missense_variant 0.86 ethambutol
embB 4248169 c.1656C>G synonymous_variant 0.87 ethambutol
embB 4248172 c.1659G>C synonymous_variant 0.87 ethambutol
embB 4248175 c.1662G>C synonymous_variant 0.86 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.86 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.86 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.85 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 0.87 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embB 4248241 c.1728C>T synonymous_variant 0.86 ethambutol
embB 4248266 c.1753C>T synonymous_variant 0.87 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.87 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.81 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.82 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.75 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.66 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.65 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.63 ethambutol
embB 4248360 c.1847delCinsATGAG frameshift_variant&missense_variant 0.64 ethambutol
embB 4248388 c.1875G>C synonymous_variant 0.72 ethambutol
embB 4248407 c.1894_1896delTTAinsCTG synonymous_variant 0.69 ethambutol
embB 4248410 p.Phe633Leu missense_variant 0.68 ethambutol
embB 4248416 p.Leu635Val missense_variant 0.69 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.68 ethambutol Not assoc w R - Interim
embB 4248432 p.Trp640Phe missense_variant 0.66 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.63 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.51 ethambutol
embB 4248475 c.1962G>A synonymous_variant 0.51 ethambutol
embB 4248488 p.Ala659Ser missense_variant 0.51 ethambutol
embB 4248504 p.Asp664Val missense_variant 0.6 ethambutol
embB 4248508 c.1995G>A synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embB 4248514 c.2001A>C synonymous_variant 0.61 ethambutol
embB 4248515 p.Val668Ile missense_variant 0.61 ethambutol Not assoc w R - Interim
embB 4248526 c.2013C>A synonymous_variant 0.58 ethambutol
embB 4249291 c.2778C>G synonymous_variant 0.68 ethambutol
embB 4249297 c.2784G>C synonymous_variant 0.69 ethambutol
embB 4249307 p.Leu932Val missense_variant 0.71 ethambutol
embB 4249321 c.2808A>C synonymous_variant 0.71 ethambutol
embB 4249322 p.Ala937Ser missense_variant 0.71 ethambutol
embB 4249325 p.Lys938Glu missense_variant 0.68 ethambutol
embB 4249336 c.2823C>G synonymous_variant 0.75 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.75 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.74 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.73 ethambutol
embB 4249360 c.2847G>C synonymous_variant 0.76 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.77 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.78 ethambutol
embB 4249414 c.2901G>C synonymous_variant 0.78 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.77 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.75 ethambutol Uncertain significance
embB 4249432 c.2919A>C synonymous_variant 0.73 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.62 ethambutol
embB 4249447 c.2934G>C synonymous_variant 0.62 ethambutol
embB 4249450 c.2937C>T synonymous_variant 0.62 ethambutol Not assoc w R - Interim
embB 4249453 c.2940G>C synonymous_variant 0.63 ethambutol
embB 4249462 c.2949G>C synonymous_variant 0.67 ethambutol
embB 4249466 c.2953C>T synonymous_variant 0.6 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.61 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.64 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.64 ethambutol
embB 4249492 c.2979C>G synonymous_variant 0.65 ethambutol
embB 4249506 p.Gln998Arg missense_variant 0.64 ethambutol
embB 4249510 c.2997G>C synonymous_variant 0.64 ethambutol
embB 4249514 c.3001C>T synonymous_variant 0.63 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.62 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4249528 c.3015C>T synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.59 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.58 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.58 ethambutol
embB 4249540 c.3027C>T synonymous_variant 0.59 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.65 ethambutol
embB 4249552 c.3039C>T synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embB 4249558 c.3045A>G synonymous_variant 0.71 ethambutol
embB 4249567 c.3054C>T synonymous_variant 0.75 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.77 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.76 ethambutol
embB 4249600 c.3087A>G synonymous_variant 0.75 ethambutol
embB 4249609 c.3096T>C synonymous_variant 0.74 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.8 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.79 ethambutol
embB 4249640 c.3127T>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4249648 c.3135G>C synonymous_variant 0.8 ethambutol
embB 4249657 c.3144C>G synonymous_variant 0.79 ethambutol
embB 4249661 p.Ala1050Ser missense_variant 0.77 ethambutol
embB 4249686 p.Ala1058Gly missense_variant 0.77 ethambutol
embB 4249690 c.3177C>T synonymous_variant 0.77 ethambutol
embB 4249702 c.3189C>G synonymous_variant 0.69 ethambutol
embB 4249723 c.3210G>C synonymous_variant 0.4 ethambutol
embB 4249726 c.3213C>G synonymous_variant 0.37 ethambutol
aftB 4267247 c.1590G>A synonymous_variant 0.31 ethambutol
aftB 4267289 p.Ala516Gln missense_variant 0.3 ethambutol
aftB 4267298 c.1539A>G synonymous_variant 0.3 ethambutol
aftB 4267305 p.Val511Ala missense_variant 0.3 ethambutol
aftB 4267310 c.1527G>T synonymous_variant 0.3 ethambutol
aftB 4267331 c.1506C>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
aftB 4267355 c.1482A>G synonymous_variant 0.27 ethambutol
aftB 4267510 p.Asn443Asp missense_variant 0.32 ethambutol
aftB 4267511 c.1326C>T synonymous_variant 0.32 ethambutol Not assoc w R - Interim
aftB 4267517 c.1320A>C synonymous_variant 0.35 ethambutol
aftB 4267520 c.1317T>C synonymous_variant 0.37 ethambutol Not assoc w R - Interim
aftB 4267523 c.1314G>T synonymous_variant 0.41 ethambutol
aftB 4267529 c.1308T>G synonymous_variant 0.48 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 0.48 ethambutol
aftB 4267538 c.1299G>C synonymous_variant 0.52 ethambutol
aftB 4267544 c.1293T>C synonymous_variant 0.5 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 0.54 ethambutol
aftB 4267571 c.1266T>C synonymous_variant 0.58 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 0.65 ethambutol
aftB 4267578 p.His420Arg missense_variant 0.65 ethambutol
aftB 4267586 c.1251C>G synonymous_variant 0.65 ethambutol
aftB 4267595 c.1242C>T synonymous_variant 0.61 ethambutol
aftB 4267619 c.1218C>G synonymous_variant 0.5 ethambutol
aftB 4267622 c.1215G>C synonymous_variant 0.5 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.5 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.5 ethambutol
aftB 4267648 p.Asp397Tyr missense_variant 0.53 ethambutol
aftB 4268042 c.795A>G synonymous_variant 0.5 ethambutol
aftB 4268048 c.789G>C synonymous_variant 0.48 ethambutol
aftB 4268052 p.Arg262Ala missense_variant 0.46 ethambutol
aftB 4268066 p.Val257Leu missense_variant 0.54 ethambutol
aftB 4268069 c.768C>T synonymous_variant 0.52 ethambutol Not assoc w R - Interim
aftB 4268078 c.759C>G synonymous_variant 0.63 ethambutol
aftB 4268081 c.756A>G synonymous_variant 0.63 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.7 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.71 ethambutol Not assoc w R - Interim
aftB 4268105 c.732T>C synonymous_variant 0.73 ethambutol
aftB 4268114 c.723G>C synonymous_variant 0.72 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 0.71 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.71 ethambutol
aftB 4268138 c.699A>G synonymous_variant 0.69 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.65 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.65 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
aftB 4268194 p.Leu215Val missense_variant 0.56 ethambutol
aftB 4268200 p.Ile213Val missense_variant 0.56 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.56 ethambutol
aftB 4268222 c.615G>C synonymous_variant 0.46 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.4 ethambutol
aftB 4268228 c.609C>G synonymous_variant 0.38 ethambutol
aftB 4268233 p.Ile202Val missense_variant 0.38 ethambutol Uncertain significance
aftB 4268236 c.601T>C synonymous_variant 0.37 ethambutol
aftB 4268252 c.585G>C synonymous_variant 0.26 ethambutol
aftB 4268386 c.451T>C synonymous_variant 0.44 ethambutol
aftB 4268396 c.441T>C synonymous_variant 0.44 ethambutol
aftB 4268404 c.433T>C synonymous_variant 0.47 ethambutol
aftB 4268405 p.Val144Thr missense_variant 0.47 ethambutol
aftB 4268417 c.420G>A synonymous_variant 0.44 ethambutol
aftB 4268441 c.396C>T synonymous_variant 0.47 ethambutol
aftB 4268444 c.393C>A synonymous_variant 0.47 ethambutol
aftB 4268450 c.387A>C synonymous_variant 0.47 ethambutol
aftB 4268453 p.Val128Leu missense_variant 0.47 ethambutol
aftB 4268462 c.375T>C synonymous_variant 0.48 ethambutol
aftB 4268465 p.Val124Ala missense_variant 0.48 ethambutol
aftB 4268474 c.363G>T synonymous_variant 0.62 ethambutol
aftB 4268480 c.357G>C synonymous_variant 0.68 ethambutol
aftB 4268483 p.Leu118Val missense_variant 0.68 ethambutol
aftB 4268491 p.Ile116Val missense_variant 0.65 ethambutol
aftB 4268497 c.340C>A synonymous_variant 0.65 ethambutol
aftB 4268498 c.339T>C synonymous_variant 0.65 ethambutol
aftB 4268516 c.321A>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
aftB 4268940 c.-104T>C upstream_gene_variant 0.44 ethambutol
aftB 4268949 c.-113T>C upstream_gene_variant 0.44 ethambutol
aftB 4268955 c.-119A>G upstream_gene_variant 0.46 ethambutol
aftB 4268958 c.-122A>C upstream_gene_variant 0.46 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.63 ethambutol
aftB 4268994 c.-158T>C upstream_gene_variant 0.72 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 0.75 ethambutol
aftB 4269009 c.-173A>G upstream_gene_variant 0.76 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.76 ethambutol
aftB 4269018 c.-182G>C upstream_gene_variant 0.78 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.79 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.78 ethambutol
ubiA 4269075 p.Ile253Val missense_variant 0.82 ethambutol
aftB 4269103 c.-268_-267delAGinsTC upstream_gene_variant 0.82 ethambutol
ubiA 4269105 p.Tyr243His missense_variant 0.82 ethambutol
ubiA 4269110 p.Gly242Arg missense_variant 0.83 ethambutol
aftB 4269123 c.-287T>C upstream_gene_variant 0.83 ethambutol
ubiA 4269135 c.699C>T synonymous_variant 0.86 ethambutol Not assoc w R - Interim
ubiA 4269143 p.Leu231Val missense_variant 0.84 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.84 ethambutol Not assoc w R - Interim
ubiA 4269164 p.Leu224Met missense_variant 0.83 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.82 ethambutol
ubiA 4269209 p.Ser209Ala missense_variant 0.81 ethambutol
ubiA 4269220 p.Ala205Val missense_variant 0.8 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.77 ethambutol
ubiA 4269240 p.Leu198Val missense_variant 0.74 ethambutol Uncertain significance
ubiA 4269243 p.His197Gln missense_variant 0.74 ethambutol
aftB 4269285 c.-449T>G upstream_gene_variant 0.68 ethambutol
aftB 4269291 c.-455A>G upstream_gene_variant 0.67 ethambutol
ubiA 4269294 p.Met180Val missense_variant 0.67 ethambutol Uncertain significance
ubiA 4269299 p.Ile179Phe missense_variant 0.67 ethambutol
aftB 4269300 c.-464G>T upstream_gene_variant 0.65 ethambutol
ubiA 4269314 p.Lys174Gln missense_variant 0.65 ethambutol
ubiA 4269315 c.519C>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
aftB 4269320 c.-484C>T upstream_gene_variant 0.67 ethambutol
ubiA 4269327 p.Lys169Asp missense_variant 0.67 ethambutol
ubiA 4269336 p.Val166Ala missense_variant 0.68 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.69 ethambutol
aftB 4269354 c.-518C>G upstream_gene_variant 0.64 ethambutol
ubiA 4269359 p.Ile159Leu missense_variant 0.61 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 0.59 ethambutol
aftB 4269366 c.-530G>C upstream_gene_variant 0.6 ethambutol
aftB 4269375 c.-539G>C upstream_gene_variant 0.58 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.55 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269392 p.Val148Met missense_variant 0.51 ethambutol Uncertain significance
aftB 4269402 c.-566T>C upstream_gene_variant 0.3 ethambutol
aftB 4269528 c.-692G>C upstream_gene_variant 0.37 ethambutol
aftB 4269555 c.-719C>G upstream_gene_variant 0.38 ethambutol
aftB 4269570 c.-736_-734delAGGinsCGC upstream_gene_variant 0.41 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 0.41 ethambutol
aftB 4269579 c.-743C>G upstream_gene_variant 0.41 ethambutol
ubiA 4269582 c.252C>T synonymous_variant 0.42 ethambutol Not assoc w R - Interim
aftB 4269588 c.-752G>C upstream_gene_variant 0.4 ethambutol
aftB 4269594 c.-758A>C upstream_gene_variant 0.41 ethambutol
ubiA 4269598 p.Glu79Ala missense_variant 0.41 ethambutol Uncertain significance
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4269612 c.-776T>C upstream_gene_variant 0.47 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 0.51 ethambutol
ubiA 4269627 p.Val69Ile missense_variant 0.55 ethambutol
aftB 4269636 c.-800C>G upstream_gene_variant 0.63 ethambutol
aftB 4269639 c.-803C>G upstream_gene_variant 0.62 ethambutol
aftB 4269651 c.-815G>C upstream_gene_variant 0.61 ethambutol
aftB 4269660 c.-824C>G upstream_gene_variant 0.57 ethambutol
ubiA 4269665 p.Met57Val missense_variant 0.57 ethambutol
ubiA 4269668 p.Ser56Ala missense_variant 0.57 ethambutol
ubiA 4269676 p.Ser53Thr missense_variant 0.55 ethambutol
aftB 4269678 c.-842C>G upstream_gene_variant 0.55 ethambutol
aftB 4269681 c.-845G>C upstream_gene_variant 0.55 ethambutol
ubiA 4269688 p.Val49Thr missense_variant 0.56 ethambutol
ubiA 4269705 p.Gly43Pro missense_variant 0.55 ethambutol
aftB 4269716 c.-880T>C upstream_gene_variant 0.54 ethambutol
aftB 4269720 c.-884C>G upstream_gene_variant 0.55 ethambutol
ubiA 4269741 p.Leu31Ile missense_variant 0.53 ethambutol
aftB 4269744 c.-908G>C upstream_gene_variant 0.54 ethambutol
aftB 4269750 c.-914A>G upstream_gene_variant 0.56 ethambutol
ubiA 4269759 c.75G>A synonymous_variant 0.48 ethambutol Not assoc w R - Interim
aftB 4269774 c.-938G>C upstream_gene_variant 0.4 ethambutol
ethA 4326432 p.Leu348Phe missense_variant 1.0 ethionamide Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4407873 c.330G>T synonymous_variant 1.0 streptomycin Not assoc w R