TB-Profiler result

Run: SRR13861424
Summary

Run ID: SRR13861424

Sample name:

Date: 03-04-2023 09:31:24

Number of reads: 189941

Percentage reads mapped: 4.75

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761131 p.Gly442Glu missense_variant 0.31 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8880 p.Lys527Gln missense_variant 0.88
gyrA 9182 c.1881T>C synonymous_variant 0.22
gyrA 9191 c.1890G>C synonymous_variant 0.22
gyrA 9200 c.1899A>G synonymous_variant 0.2
gyrA 9204 p.Ser635Thr missense_variant 0.22
gyrA 9227 c.1926C>G synonymous_variant 0.22
gyrA 9230 c.1929T>C synonymous_variant 0.22
gyrA 9242 c.1941A>C synonymous_variant 0.2
gyrA 9252 p.Val651Ile missense_variant 0.25
gyrA 9275 c.1974G>A synonymous_variant 0.29
gyrA 9278 c.1977G>C synonymous_variant 0.33
gyrA 9281 c.1980C>G synonymous_variant 0.29
gyrA 9284 c.1983T>C synonymous_variant 0.29
gyrA 9291 c.1990C>T synonymous_variant 0.29
gyrA 9296 c.1995T>C synonymous_variant 0.29
gyrA 9304 p.Gly668Glu missense_variant 0.29
gyrA 9311 c.2010C>T synonymous_variant 0.33
gyrA 9323 c.2022C>G synonymous_variant 0.29
fgd1 490617 c.-166T>G upstream_gene_variant 0.33
fgd1 491137 p.Glu119Gln missense_variant 0.29
fgd1 491144 p.Ala121Glu missense_variant 0.29
fgd1 491166 c.384G>C synonymous_variant 0.25
fgd1 491181 c.399T>C synonymous_variant 0.25
fgd1 491191 p.Gly137Arg missense_variant 0.29
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.29
fgd1 491202 c.420G>C synonymous_variant 0.29
fgd1 491203 p.Gln141Glu missense_variant 0.29
fgd1 491212 p.Ser144Arg missense_variant 0.29
fgd1 491217 c.435T>C synonymous_variant 0.29
fgd1 491232 c.450T>C synonymous_variant 0.38
fgd1 491241 p.Asp153Glu missense_variant 0.3
fgd1 491244 c.462T>C synonymous_variant 0.3
fgd1 491259 c.477T>C synonymous_variant 0.3
fgd1 491286 c.504G>C synonymous_variant 0.25
rpoB 760118 c.312T>C synonymous_variant 0.5
rpoB 760121 c.315T>C synonymous_variant 0.5
rpoB 760130 p.Asp108Glu missense_variant 0.5
rpoB 760139 c.333A>G synonymous_variant 0.5
rpoB 760142 c.336C>G synonymous_variant 0.5
rpoB 760181 c.375T>C synonymous_variant 0.5
rpoB 760184 c.378A>G synonymous_variant 0.5
rpoB 760196 c.390C>G synonymous_variant 0.5
rpoB 760223 c.417T>C synonymous_variant 0.29
rpoB 760235 c.429T>C synonymous_variant 0.29
rpoB 760972 p.Arg389Leu missense_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 0.2
rpoB 761126 c.1320G>T synonymous_variant 0.31
rpoB 761129 c.1323G>C synonymous_variant 0.31
rpoB 761133 p.Leu443Ile missense_variant 0.36
rpoB 761150 c.1344A>C synonymous_variant 0.43
rpoB 761151 p.Leu449Val missense_variant 0.29
rpoB 761156 c.1350G>C synonymous_variant 0.29
rpoB 761162 c.1356G>C synonymous_variant 0.29
rpoB 761165 c.1359G>C synonymous_variant 0.4
rpoB 761168 c.1362C>G synonymous_variant 0.4
rpoB 761178 p.Ser458Thr missense_variant 0.27
rpoB 761192 c.1386C>G synonymous_variant 0.24
rpoB 761195 c.1389G>C synonymous_variant 0.24
rpoB 761196 p.Leu464Phe missense_variant 0.24
rpoB 761204 c.1398C>T synonymous_variant 0.27
rpoB 761207 c.1401C>T synonymous_variant 0.29
rpoB 761213 c.1407G>A synonymous_variant 0.29
rpoB 761220 p.Ser472Thr missense_variant 0.31
rpoB 761234 c.1428G>C synonymous_variant 0.29
rpoB 761235 p.Met477Val missense_variant 0.31
rpoB 761255 c.1449T>G synonymous_variant 0.18
rpoB 761261 c.1455G>T synonymous_variant 0.22
rpoB 762254 c.2448T>C synonymous_variant 0.4
rpoC 762860 c.-510G>C upstream_gene_variant 0.27
rpoC 762863 c.-507T>C upstream_gene_variant 0.2
rpoB 762878 p.Ile1024Met missense_variant 0.22
rpoB 762879 p.Met1025Leu missense_variant 0.22
rpoB 762888 p.His1028Asn missense_variant 0.2
rpoB 762911 p.Ile1035Met missense_variant 0.2
rpoC 762920 c.-450C>T upstream_gene_variant 0.2
rpoC 762929 c.-441G>C upstream_gene_variant 0.25
rpoB 762930 p.Pro1042Ser missense_variant 0.18
rpoC 762936 c.-434_-432delTCGinsAGC upstream_gene_variant 0.18
rpoB 762939 p.Met1045Leu missense_variant 0.18
rpoB 762942 p.Ile1046Val missense_variant 0.2
rpoC 762962 c.-408C>T upstream_gene_variant 0.17
rpoC 762971 c.-399G>A upstream_gene_variant 0.18
rpoC 762983 c.-387C>T upstream_gene_variant 0.18
rpoC 762989 c.-381G>C upstream_gene_variant 0.27
rpoC 762995 c.-375G>T upstream_gene_variant 0.3
rpoC 764401 c.1032C>T synonymous_variant 0.67
rpoC 764404 c.1035C>T synonymous_variant 0.67
rpoC 764405 c.1036A>C synonymous_variant 0.67
rpoC 764419 c.1050C>T synonymous_variant 0.67
rpoC 764428 c.1059G>T synonymous_variant 0.67
rpoC 764434 c.1065A>G synonymous_variant 0.67
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.67
rpoC 764441 p.Ile358Leu missense_variant 0.67
rpoC 764446 c.1077T>C synonymous_variant 0.67
rpoC 764451 p.Gly361Ala missense_variant 0.67
rpoC 764455 c.1086G>T synonymous_variant 0.67
rpoC 764461 p.Glu364Asp missense_variant 0.67
rpoC 764470 c.1101C>G synonymous_variant 0.67
rpoC 764471 p.Asn368Arg missense_variant 0.67
rpoC 764479 c.1110G>A synonymous_variant 0.67
rpoC 764485 c.1116G>C synonymous_variant 0.5
rpoC 764498 p.Ser377Ala missense_variant 0.5
rpoC 764503 c.1134G>C synonymous_variant 0.5
rpoC 764509 c.1140G>C synonymous_variant 0.67
rpoC 764513 p.Phe382Leu missense_variant 0.67
rpoC 764714 c.1345C>T synonymous_variant 0.25
rpoC 764720 c.1351C>T synonymous_variant 0.25
rpoC 765111 p.Met581Lys missense_variant 1.0
rpoC 765161 p.Glu598Lys missense_variant 0.8
rpoC 765540 p.Ala724Val missense_variant 1.0
rpoC 765835 c.2466C>T synonymous_variant 0.25
rpoC 765883 c.2514C>G synonymous_variant 0.29
rpoC 765886 c.2517C>G synonymous_variant 0.33
rpoC 765892 c.2523T>C synonymous_variant 0.33
rpoC 765928 c.2559C>G synonymous_variant 0.33
rpoC 765994 c.2625A>T synonymous_variant 0.33
rpoC 766009 c.2640G>C synonymous_variant 0.33
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.33
rpoC 766021 c.2652G>C synonymous_variant 0.33
rpoC 766043 p.Gln892Glu missense_variant 0.29
rpoC 766054 c.2685C>G synonymous_variant 0.29
rpoC 766069 c.2700G>A synonymous_variant 0.33
rpoC 766082 p.Ala905Gln missense_variant 0.33
rpoC 766096 c.2727G>C synonymous_variant 0.33
rpoC 766105 c.2736C>T synonymous_variant 0.33
rpoC 766129 c.2760C>G synonymous_variant 0.33
rpoC 766135 c.2766G>A synonymous_variant 0.33
rpoC 766408 c.3039C>T synonymous_variant 0.29
rpoC 766426 c.3057C>T synonymous_variant 0.29
rpoC 766483 c.3114G>C synonymous_variant 0.22
rpoC 766484 p.Val1039Ile missense_variant 0.22
rpoC 766492 c.3123T>C synonymous_variant 0.22
rpoC 766495 c.3126C>T synonymous_variant 0.22
rpoC 766522 c.3153C>G synonymous_variant 0.43
rpoC 766528 c.3159T>C synonymous_variant 0.43
rpoC 766531 c.3162G>T synonymous_variant 0.43
rpoC 766543 c.3174C>T synonymous_variant 0.33
rpoC 766549 c.3180G>C synonymous_variant 0.3
rpoC 766573 c.3204T>C synonymous_variant 0.2
rpoC 766583 p.Gly1072Ser missense_variant 0.2
rpoC 766588 c.3219G>A synonymous_variant 0.2
rpoC 766591 c.3222A>G synonymous_variant 0.18
rpoC 766594 c.3225G>C synonymous_variant 0.18
rpoC 766607 p.Ile1080Leu missense_variant 0.17
rpoC 766645 c.3276A>G synonymous_variant 0.17
rpoC 766651 c.3282T>C synonymous_variant 0.15
rpoC 767068 c.3699G>T synonymous_variant 1.0
mmpR5 778439 c.-551C>A upstream_gene_variant 1.0
rpsL 781715 c.156T>C synonymous_variant 0.25
rpsL 781728 c.169T>C synonymous_variant 0.22
rpsL 781736 c.177T>C synonymous_variant 0.25
rpsL 781751 c.192G>C synonymous_variant 0.33
rpsL 781754 c.195G>C synonymous_variant 0.33
rpsL 781760 c.201T>C synonymous_variant 0.4
rpsL 781793 c.234G>C synonymous_variant 0.33
rpsL 781832 c.273T>C synonymous_variant 0.43
rpsL 781841 c.282C>G synonymous_variant 0.43
rpsL 781859 c.300T>C synonymous_variant 0.33
rpsL 781868 c.309T>C synonymous_variant 0.25
rpsL 781871 c.312G>C synonymous_variant 0.25
rpsL 781892 c.333A>G synonymous_variant 0.29
rpsL 781898 c.339A>T synonymous_variant 0.29
rpsL 781916 c.357T>C synonymous_variant 0.33
rpsL 781929 p.Gly124Ser missense_variant 0.33
rplC 801357 p.His183Gln missense_variant 1.0
fbiC 1304229 c.1301delC frameshift_variant 1.0
rrs 1472288 n.444delT non_coding_transcript_exon_variant 0.75
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.25
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.73
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.71
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.71
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.71
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.71
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.77
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.75
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.77
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.77
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.77
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.77
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.77
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.77
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.77
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.77
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.77
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.79
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.7
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.7
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.18
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.4
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.4
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.5
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.29
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.22
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.22
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.22
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.25
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.2
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.2
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.33
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.33
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.54
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.89
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.9
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.92
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.92
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.91
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.92
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.92
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.92
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.92
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.9
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.92
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.92
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.91
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.91
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.91
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.91
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.9
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.9
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.89
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.89
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.56
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.25
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.29
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.29
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.25
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.25
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.25
inhA 1674285 c.84A>G synonymous_variant 0.29
rpsA 1833724 c.183C>G synonymous_variant 0.29
rpsA 1833727 c.186G>C synonymous_variant 0.29
rpsA 1833742 c.201A>G synonymous_variant 0.29
rpsA 1833745 c.204G>C synonymous_variant 0.29
rpsA 1833787 c.246C>G synonymous_variant 0.29
rpsA 1833790 c.249T>A synonymous_variant 0.33
rpsA 1833799 c.258C>G synonymous_variant 0.43
rpsA 1833811 c.270G>C synonymous_variant 0.43
rpsA 1833838 c.297G>C synonymous_variant 0.4
rpsA 1833841 c.300C>G synonymous_variant 0.36
rpsA 1833847 c.306C>G synonymous_variant 0.3
rpsA 1833856 c.315A>G synonymous_variant 0.27
rpsA 1833862 c.321G>T synonymous_variant 0.3
rpsA 1833874 c.333T>C synonymous_variant 0.33
rpsA 1833928 c.387G>C synonymous_variant 0.22
rpsA 1833940 c.399C>G synonymous_variant 0.25
rpsA 1833970 c.429G>C synonymous_variant 0.22
tlyA 1917929 c.-11T>C upstream_gene_variant 0.29
tlyA 1917943 p.Ala2Ser missense_variant 0.33
tlyA 1917951 c.12T>C synonymous_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 0.33
tlyA 1917981 c.42G>C synonymous_variant 0.4
tlyA 1917989 p.Ala17Gly missense_variant 0.6
tlyA 1917993 c.54A>G synonymous_variant 0.4
tlyA 1917996 c.57A>G synonymous_variant 0.4
tlyA 1917999 c.60T>C synonymous_variant 0.4
tlyA 1918002 c.63A>G synonymous_variant 0.33
tlyA 1918015 c.76T>C synonymous_variant 0.4
tlyA 1918036 p.Arg33Ser missense_variant 0.5
tlyA 1918048 p.Leu37Met missense_variant 0.5
ndh 2102525 p.Phe173Tyr missense_variant 1.0
ndh 2102538 c.504_505insT frameshift_variant 1.0
Rv1979c 2222978 p.Ile63Phe missense_variant 1.0
Rv1979c 2223052 p.Glu38Val missense_variant 1.0
pncA 2289415 c.-174C>G upstream_gene_variant 1.0
kasA 2518057 c.-58A>C upstream_gene_variant 1.0
kasA 2518747 c.633C>G synonymous_variant 0.4
kasA 2518768 c.654C>G synonymous_variant 0.4
kasA 2518783 c.669T>C synonymous_variant 0.33
kasA 2518792 c.678C>G synonymous_variant 0.33
kasA 2518795 c.681C>G synonymous_variant 0.33
kasA 2518799 p.Pro229Ser missense_variant 0.67
kasA 2518822 c.708C>G synonymous_variant 0.4
kasA 2518825 c.711T>C synonymous_variant 0.33
kasA 2518843 c.729T>C synonymous_variant 0.33
kasA 2518855 c.741C>G synonymous_variant 0.29
kasA 2518864 c.750G>C synonymous_variant 0.22
eis 2714983 p.Ala117Glu missense_variant 1.0
ahpC 2726579 c.387T>C synonymous_variant 0.4
ahpC 2726591 c.399C>G synonymous_variant 0.5
ahpC 2726593 p.Val134Ala missense_variant 0.5
ahpC 2726600 c.408T>C synonymous_variant 0.4
ahpC 2726612 c.420C>G synonymous_variant 0.33
ahpC 2726638 p.Ala149Val missense_variant 0.33
ahpC 2726645 c.453C>G synonymous_variant 0.33
ahpC 2726657 c.465A>C synonymous_variant 0.33
ahpC 2726669 p.Asp159Glu missense_variant 0.4
ahpC 2726672 c.480G>A synonymous_variant 0.4
ahpC 2726675 c.483A>G synonymous_variant 0.4
ahpC 2726681 c.489A>G synonymous_variant 0.4
ahpC 2726687 c.495C>G synonymous_variant 0.4
ahpC 2726690 c.498C>T synonymous_variant 0.4
ahpC 2726693 c.501C>G synonymous_variant 0.4
ahpC 2726696 c.504C>G synonymous_variant 0.4
ahpC 2726717 c.525A>G synonymous_variant 0.33
folC 2747355 p.Val82Ile missense_variant 0.4
folC 2747359 c.240C>G synonymous_variant 0.4
folC 2747362 c.237G>C synonymous_variant 0.4
folC 2747394 p.Ile69Val missense_variant 0.67
folC 2747395 c.204T>C synonymous_variant 0.67
folC 2747401 c.198G>C synonymous_variant 0.5
fprA 3474209 p.Glu68Val missense_variant 0.33
fprA 3474283 p.Leu93Val missense_variant 0.4
fprA 3474993 c.987G>C synonymous_variant 0.22
fprA 3475014 p.Asp336Glu missense_variant 0.2
fprA 3475015 p.Gln337Lys missense_variant 0.2
fprA 3475019 p.Ser338Thr missense_variant 0.2
fprA 3475022 p.Gly339Ala missense_variant 0.18
fprA 3475036 p.Val344Thr missense_variant 0.17
fprA 3475047 c.1041A>G synonymous_variant 0.23
fprA 3475048 p.Ile348Val missense_variant 0.15
fprA 3475051 p.Asn349Asp missense_variant 0.15
fprA 3475061 p.Pro352Arg missense_variant 0.15
fprA 3475068 c.1062A>G synonymous_variant 0.17
fprA 3475074 c.1068C>G synonymous_variant 0.17
fprA 3475077 c.1071C>G synonymous_variant 0.17
fbiA 3640404 c.-139C>A upstream_gene_variant 1.0
fbiB 3642056 c.522C>G synonymous_variant 1.0
rpoA 3877782 c.726T>C synonymous_variant 0.5
rpoA 3877967 p.Thr181Ser missense_variant 1.0
rpoA 3877972 c.535delG frameshift_variant 1.0
rpoA 3878370 c.138T>C synonymous_variant 0.25
rpoA 3878376 c.132G>C synonymous_variant 0.3
rpoA 3878385 c.123C>G synonymous_variant 0.3
rpoA 3878391 c.117T>C synonymous_variant 0.33
rpoA 3878396 c.112C>T synonymous_variant 0.3
rpoA 3878436 c.72A>G synonymous_variant 0.3
rpoA 3878442 c.66G>C synonymous_variant 0.3
rpoA 3878454 c.54A>C synonymous_variant 0.25
rpoA 3878472 p.Asp12Glu missense_variant 0.2
rpoA 3878478 c.30C>G synonymous_variant 0.2
rpoA 3878490 c.18C>A synonymous_variant 0.2
rpoA 3878496 c.12A>T synonymous_variant 0.2
clpC1 4039226 c.1479T>C synonymous_variant 0.18
clpC1 4039268 c.1437C>G synonymous_variant 0.21
clpC1 4039274 c.1431G>C synonymous_variant 0.23
clpC1 4039286 c.1419T>C synonymous_variant 0.21
clpC1 4039289 c.1416T>C synonymous_variant 0.23
clpC1 4039295 c.1410A>C synonymous_variant 0.23
clpC1 4039298 c.1407T>C synonymous_variant 0.23
clpC1 4039319 c.1386T>C synonymous_variant 0.3
clpC1 4039322 c.1383T>C synonymous_variant 0.3
clpC1 4039328 c.1377A>G synonymous_variant 0.3
clpC1 4039334 c.1371G>C synonymous_variant 0.33
clpC1 4039337 p.Thr456Gln missense_variant 0.3
clpC1 4039391 c.1314T>G synonymous_variant 0.22
clpC1 4039409 c.1296T>C synonymous_variant 0.22
clpC1 4039412 c.1293T>G synonymous_variant 0.22
clpC1 4039430 c.1275T>C synonymous_variant 0.22
clpC1 4039442 c.1263A>G synonymous_variant 0.25
clpC1 4039448 c.1257A>G synonymous_variant 0.29
clpC1 4039454 c.1251A>G synonymous_variant 0.29
clpC1 4039463 c.1242C>G synonymous_variant 0.25
clpC1 4039466 c.1239T>C synonymous_variant 0.25
clpC1 4039469 c.1236T>C synonymous_variant 0.25
clpC1 4039481 c.1224T>G synonymous_variant 0.22
clpC1 4039484 c.1221T>G synonymous_variant 0.22
clpC1 4039694 c.1011G>C synonymous_variant 0.22
clpC1 4039777 c.927_928insG frameshift_variant 1.0
embB 4247545 p.Ser344Arg missense_variant 1.0
aftB 4268812 p.Ser9Pro missense_variant 1.0
ubiA 4269117 p.Glu239Asp missense_variant 0.33
aftB 4269123 c.-287T>C upstream_gene_variant 0.33
ubiA 4269141 p.Leu231Val missense_variant 0.33
aftB 4269144 c.-308C>G upstream_gene_variant 0.33
ubiA 4269149 p.Val229Leu missense_variant 0.33
aftB 4269183 c.-347T>C upstream_gene_variant 0.4