TB-Profiler result

Run: SRR5818434
Summary

Run ID: SRR5818434

Sample name:

Date: 04-04-2023 11:27:37

Number of reads: 111301

Percentage reads mapped: 97.9

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
mmpL5 779116 c.-636G>A upstream_gene_variant 0.17
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.42
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.43
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.44
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.13
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.15
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.16
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.16
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.15
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.14
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.15
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.15
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.14
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.14
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.14
inhA 1674678 c.477C>T synonymous_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289184 p.Ala20Thr missense_variant 0.23
ahpC 2726184 c.-9A>C upstream_gene_variant 0.22
ethA 4326350 p.Ser375Phe missense_variant 0.16
ethA 4326764 p.Ala237Val missense_variant 0.26