TB-Profiler result

Run: SRR5818442
Summary

Run ID: SRR5818442

Sample name:

Date: 04-04-2023 11:30:47

Number of reads: 666661

Percentage reads mapped: 99.62

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.17 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7770 p.Asp157His missense_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.78
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.83
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.71
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.15
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.26
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.19
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.19
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.25
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.25
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.22
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.22
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.25
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.24
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.24
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.23
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.24
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.26
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.26
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.21
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.47
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.26
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.5
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.13
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.18
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.33
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.21
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.3
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.14
rrs 1472736 n.891G>A non_coding_transcript_exon_variant 0.91
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.33
ethA 4326764 p.Ala237Val missense_variant 0.31
gid 4407588 c.615A>G synonymous_variant 1.0