TB-Profiler result

Run: SRR8692858
Summary

Run ID: SRR8692858

Sample name:

Date: 13-08-2023 19:33:47

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6730 c.-572A>C upstream_gene_variant 0.1
gyrA 6745 c.-557T>C upstream_gene_variant 0.12
gyrA 6751 c.-551G>C upstream_gene_variant 0.12
gyrA 6760 c.-542G>C upstream_gene_variant 0.12
gyrA 6775 c.-527G>A upstream_gene_variant 0.12
gyrA 6784 c.-518C>T upstream_gene_variant 0.12
gyrA 6793 c.-509T>C upstream_gene_variant 0.13
gyrB 6794 p.Ile519Leu missense_variant 0.13
gyrB 6798 p.Gly520Ala missense_variant 0.14
gyrA 6808 c.-494C>G upstream_gene_variant 0.14
gyrA 6811 c.-491C>T upstream_gene_variant 0.14
rpoB 760172 c.366G>C synonymous_variant 0.19
rpoB 760181 c.375T>G synonymous_variant 0.18
rpoB 760184 c.378A>G synonymous_variant 0.18
rpoB 760235 c.429T>C synonymous_variant 0.25
rpoB 760244 c.438G>C synonymous_variant 0.25
rpoB 760256 c.450C>T synonymous_variant 0.24
rpoB 760283 c.477G>C synonymous_variant 0.25
rpoB 760298 c.492G>C synonymous_variant 0.27
rpoC 763486 c.117T>C synonymous_variant 0.15
rpoC 763495 c.126G>A synonymous_variant 0.14
rpoC 763546 c.177A>G synonymous_variant 0.11
mmpL5 776766 p.Ala572Val missense_variant 0.14
rpsL 781595 c.36T>C synonymous_variant 0.1
rpsL 781605 p.Ile16Val missense_variant 0.11
rpsL 781608 p.Ser17Ala missense_variant 0.12
rplC 800618 c.-191T>C upstream_gene_variant 0.12
Rv1258c 1406686 p.Val219Ile missense_variant 0.95
embR 1416290 p.Gln353Arg missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471830 n.-16A>G upstream_gene_variant 0.33
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.12
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.29
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.4
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.43
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.5
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.5
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.45
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.21
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.21
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.19
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.19
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.18
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.18
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.18
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.19
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.19
rrs 1473067 n.1222C>A non_coding_transcript_exon_variant 0.12
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.42
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.45
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.45
rrs 1473169 n.1324A>G non_coding_transcript_exon_variant 0.15
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.16
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.18
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.25
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.18
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.25
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.22
rrl 1474323 n.666C>T non_coding_transcript_exon_variant 0.25
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.33
rrl 1474669 n.1015delC non_coding_transcript_exon_variant 0.67
rrl 1474739 n.1082G>T non_coding_transcript_exon_variant 0.2
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.2
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.2
rrl 1474762 n.1105G>T non_coding_transcript_exon_variant 0.2
rrl 1474788 n.1131G>T non_coding_transcript_exon_variant 0.17
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.17
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.17
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.22
rrl 1475186 n.1529C>A non_coding_transcript_exon_variant 0.2
rrl 1475222 n.1565G>A non_coding_transcript_exon_variant 0.29
rrl 1475387 n.1730C>A non_coding_transcript_exon_variant 0.33
rrl 1475400 n.1743C>A non_coding_transcript_exon_variant 0.33
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.71
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.71
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.71
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.71
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.77
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.77
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.77
rrl 1475788 n.2131C>A non_coding_transcript_exon_variant 0.13
rrl 1475927 n.2270G>T non_coding_transcript_exon_variant 0.57
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.14
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.14
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.18
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.18
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.18
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.18
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.2
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.2
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.27
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.38
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.3
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.3
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.3
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.3
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.3
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.3
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.27
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.42
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.42
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.45
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.5
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.5
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.44
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.25
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.25
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.53
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.5
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.7
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.55
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.36
rrl 1476656 n.2999G>T non_coding_transcript_exon_variant 0.18
rpsA 1833689 p.Glu50* stop_gained 0.2
rpsA 1833745 c.204G>C synonymous_variant 0.14
rpsA 1833760 c.219C>T synonymous_variant 0.14
rpsA 1833787 c.246C>G synonymous_variant 0.11
rpsA 1833790 c.249T>C synonymous_variant 0.11
ald 3087455 p.Cys212Trp missense_variant 0.1
clpC1 4038755 c.1950G>C synonymous_variant 0.13
clpC1 4038773 c.1932T>C synonymous_variant 0.12
clpC1 4038779 c.1926C>G synonymous_variant 0.11
clpC1 4038782 c.1923G>C synonymous_variant 0.11
clpC1 4038795 p.Ser637Thr missense_variant 0.11