TB-Profiler result

Run: ERR1199087
Summary

Run ID: ERR1199087

Sample name:

Date: 15-08-2022 10:09:16

Number of reads: 4206129

Percentage reads mapped: 88.54

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.28
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.46
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.39
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.32
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.29
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.12
rrs 1472333 n.488G>T non_coding_transcript_exon_variant 0.12
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.25
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 0.26
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.21
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.14
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.13
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.33
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.3
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.22
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.58
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.47
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.22
rrs 1472911 n.1066T>C non_coding_transcript_exon_variant 0.38
rrs 1472915 n.1070G>A non_coding_transcript_exon_variant 0.42
rrs 1472918 n.1073A>G non_coding_transcript_exon_variant 0.42
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.17
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.11
rrs 1473353 n.1508C>T non_coding_transcript_exon_variant 0.26
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.25
rrl 1474848 n.1191G>T non_coding_transcript_exon_variant 0.37
rrl 1474851 n.1194T>C non_coding_transcript_exon_variant 0.36
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.26
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.27
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.27
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.23
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.3
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.29
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.33
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.43
rrl 1476408 n.2751G>T non_coding_transcript_exon_variant 0.32
rrl 1476413 n.2756A>C non_coding_transcript_exon_variant 0.3
rrl 1476414 n.2757T>A non_coding_transcript_exon_variant 0.3
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.55
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.48
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.51
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.17
rrl 1476543 n.2886G>T non_coding_transcript_exon_variant 0.14
rrl 1476567 n.2910C>A non_coding_transcript_exon_variant 0.19
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.19
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.18
inhA 1674837 c.636C>A synonymous_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169866 c.747G>C synonymous_variant 0.16
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.21
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0