TB-Profiler result

Run: ERR2228822
Summary

Run ID: ERR2228822

Sample name:

Date: 31-03-2023 16:22:02

Number of reads: 36478

Percentage reads mapped: 3.55

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.94 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5265 p.Gln9Arg missense_variant 0.67
rpoC 763468 c.99G>T synonymous_variant 0.67
rpsL 781587 p.Lys10* stop_gained 1.0
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.8
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.75
rrs 1471900 n.55C>T non_coding_transcript_exon_variant 0.67
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.67
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.8
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.8
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.92
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.92
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.92
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 1.0
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.88
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.88
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.88
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.88
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.86
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.83
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.83
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.67
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.67
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.67
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.75
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.62
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.57
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.57
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.57
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.5
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.5
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.6
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.5
rrs 1472543 n.699_700delCA non_coding_transcript_exon_variant 0.5
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.8
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.89
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.8
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.8
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.73
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.82
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.79
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.8
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.71
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.8
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.67
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.89
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.9
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.89
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.9
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.91
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.9
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.94
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.92
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.5
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.67
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.67
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.67
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.67
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.75
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.6
rrs 1473172 n.1327T>C non_coding_transcript_exon_variant 0.6
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.6
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.5
rrs 1473191 n.1346C>T non_coding_transcript_exon_variant 0.56
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.64
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.69
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.75
rrl 1473890 n.233T>C non_coding_transcript_exon_variant 0.67
rrl 1473954 n.297A>T non_coding_transcript_exon_variant 0.75
rrl 1474236 n.579G>A non_coding_transcript_exon_variant 0.5
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.67
rrl 1474255 n.598C>T non_coding_transcript_exon_variant 0.5
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 1.0
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 1.0
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.5
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.5
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.6
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.6
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.6
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.6
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.8
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.67
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.6
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.67
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.71
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.71
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.71
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.5
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.5
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.5
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.67
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.67
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.67
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 1.0
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 1.0
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.96
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.97
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.94
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.94
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.75
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 1.0
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 1.0
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.6
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.67
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.75
fabG1 1673271 c.-169G>T upstream_gene_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv2752c 3065036 p.Asn386Tyr missense_variant 0.67
Rv2752c 3065793 c.399C>T synonymous_variant 0.4
ald 3086831 c.12T>A synonymous_variant 0.67
clpC1 4039746 p.Ile320Asn missense_variant 0.5
clpC1 4039760 c.945T>G synonymous_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0