TB-Profiler result

Run: ERR4819329
Summary

Run ID: ERR4819329

Sample name:

Date: 01-04-2023 16:03:13

Number of reads: 4318998

Percentage reads mapped: 97.14

Strain: lineage4.6.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.14
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.13
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.38
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.4
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.4
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.4
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.55
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.58
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.62
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.6
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.55
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.2
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.14
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.38
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.73
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.67
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.67
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.29
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.25
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.18
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.4
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.4
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.56
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.33
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.31
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.36
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.5
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.55
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.55
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.55
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.66
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.63
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.64
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.64
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.59
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.52
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.52
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.44
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.26
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.26
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.14
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.27
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.29
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.38
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.5
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.57
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.6
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.57
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.61
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.32
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.26
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.18
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.17
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.44
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.5
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.69
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.69
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.71
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.67
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.71
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.64
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.2
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.2
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.2
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.33
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.44
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.4
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.36
rrl 1475767 n.2110_2111insT non_coding_transcript_exon_variant 0.36
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.33
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.14
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.14
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.12
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.17
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.17
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.17
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.14
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.14
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.14
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.19
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.27
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.27
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.27
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.27
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.27
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.48
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.53
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.55
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.55
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.5
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.38
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.17
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.1
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.11
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.1
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.11
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.11
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 0.97
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyX 3067474 p.Pro158Ala missense_variant 1.0
Rv3083 3448567 p.His22Asp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612571 c.546C>T synonymous_variant 1.0
embA 4242550 c.-683C>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 1.0
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0