TB-Profiler result

Run: SRR13861386
Summary

Run ID: SRR13861386

Sample name:

Date: 03-04-2023 09:30:25

Number of reads: 506920

Percentage reads mapped: 16.91

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.2 streptomycin
katG 2154411 c.1700delT frameshift_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 0.14
gyrA 7676 c.375G>C synonymous_variant 0.13
gyrA 7683 c.382A>C synonymous_variant 0.2
gyrA 7694 c.393A>G synonymous_variant 0.19
gyrA 7697 c.396C>G synonymous_variant 0.19
gyrA 7710 c.409T>C synonymous_variant 0.13
gyrA 7760 c.459C>T synonymous_variant 0.14
gyrA 7763 c.462T>C synonymous_variant 0.15
gyrA 7799 c.498A>G synonymous_variant 0.17
gyrA 7949 c.648G>T synonymous_variant 1.0
gyrA 8123 p.Leu274Phe missense_variant 0.9
gyrA 8198 c.897T>C synonymous_variant 0.14
gyrA 8204 c.903C>T synonymous_variant 0.14
gyrA 8207 c.906T>C synonymous_variant 0.16
gyrA 8216 c.915G>A synonymous_variant 0.18
gyrA 8219 c.918T>C synonymous_variant 0.16
gyrA 8225 c.924T>C synonymous_variant 0.16
gyrA 8253 p.Ile318Leu missense_variant 0.2
gyrA 8264 c.963T>C synonymous_variant 0.21
gyrA 8267 c.966G>C synonymous_variant 0.21
gyrA 8270 c.969G>C synonymous_variant 0.21
gyrA 8283 p.Ile328Leu missense_variant 0.19
gyrA 8288 c.987T>C synonymous_variant 0.19
gyrA 8294 c.993T>C synonymous_variant 0.33
gyrA 8324 c.1023T>C synonymous_variant 0.22
gyrA 8339 c.1038A>G synonymous_variant 0.16
gyrA 8342 c.1041G>C synonymous_variant 0.17
gyrA 8366 c.1065G>C synonymous_variant 0.22
gyrA 8375 c.1074G>C synonymous_variant 0.22
gyrA 8391 p.Tyr364His missense_variant 0.29
gyrA 8399 c.1098T>C synonymous_variant 0.29
gyrA 8420 c.1119T>C synonymous_variant 0.26
gyrA 8423 c.1122G>C synonymous_variant 0.31
gyrA 8442 c.1141C>T synonymous_variant 0.16
gyrA 8453 c.1152A>C synonymous_variant 0.16
gyrA 8462 c.1161A>G synonymous_variant 0.15
gyrA 8471 c.1170T>C synonymous_variant 0.15
gyrA 8480 c.1179C>T synonymous_variant 0.15
gyrA 8486 c.1185T>C synonymous_variant 0.14
gyrA 8489 c.1188A>G synonymous_variant 0.15
gyrA 8498 c.1197C>T synonymous_variant 0.15
gyrA 8796 p.Ile499Val missense_variant 0.15
gyrA 8801 c.1500G>C synonymous_variant 0.17
gyrA 8810 c.1509A>C synonymous_variant 0.15
gyrA 8816 c.1515C>T synonymous_variant 0.14
gyrA 8837 c.1536C>T synonymous_variant 0.14
gyrA 8858 c.1557T>C synonymous_variant 0.16
gyrA 8915 c.1614A>G synonymous_variant 0.13
gyrA 9626 c.2325T>C synonymous_variant 0.13
gyrA 9629 c.2328C>G synonymous_variant 0.13
gyrA 9630 p.Val777Ile missense_variant 0.13
gyrA 9635 c.2334T>C synonymous_variant 0.13
gyrA 9647 c.2346C>T synonymous_variant 0.12
gyrA 9768 p.Gly823Cys missense_variant 1.0
fgd1 491166 c.384G>C synonymous_variant 0.2
fgd1 491181 c.399T>C synonymous_variant 0.18
fgd1 491191 p.Gly137Arg missense_variant 0.2
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.18
fgd1 491202 c.420G>C synonymous_variant 0.18
fgd1 491203 p.Gln141Glu missense_variant 0.17
fgd1 491212 p.Ser144Arg missense_variant 0.17
fgd1 491217 c.435T>C synonymous_variant 0.17
fgd1 491232 c.450T>C synonymous_variant 0.17
fgd1 491241 p.Asp153Glu missense_variant 0.18
fgd1 491244 c.462T>C synonymous_variant 0.18
fgd1 491259 c.477T>C synonymous_variant 0.15
fgd1 491286 c.504G>C synonymous_variant 0.13
fgd1 491292 c.510G>C synonymous_variant 0.13
fgd1 491295 c.513C>G synonymous_variant 0.13
fgd1 491296 p.Val172Ile missense_variant 0.13
mshA 575587 c.240C>A synonymous_variant 0.13
mshA 575590 c.243T>C synonymous_variant 0.12
mshA 575623 c.276C>G synonymous_variant 0.19
mshA 575629 c.282A>C synonymous_variant 0.2
mshA 575635 c.288A>C synonymous_variant 0.16
mshA 575638 c.291T>C synonymous_variant 0.17
mshA 575641 c.294A>G synonymous_variant 0.17
mshA 575648 p.Val101Gln missense_variant 0.16
mshA 575659 c.312A>G synonymous_variant 0.19
mshA 575665 c.318G>C synonymous_variant 0.2
mshA 575689 c.342G>C synonymous_variant 0.16
mshA 575695 c.348C>G synonymous_variant 0.17
mshA 575704 c.357T>C synonymous_variant 0.18
mshA 575705 c.358T>C synonymous_variant 0.18
mshA 575713 c.366G>A synonymous_variant 0.19
mshA 575719 c.372C>T synonymous_variant 0.18
rpoB 760985 c.1179G>C synonymous_variant 0.13
rpoB 760991 c.1185G>C synonymous_variant 0.13
rpoB 761021 c.1215G>C synonymous_variant 0.14
rpoB 761036 c.1230G>C synonymous_variant 0.13
rpoB 761094 c.1288C>T synonymous_variant 0.21
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.19
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.19
rpoB 761150 c.1344A>C synonymous_variant 0.21
rpoB 761165 c.1359G>C synonymous_variant 0.19
rpoB 761168 c.1362C>G synonymous_variant 0.19
rpoB 761180 c.1374A>C synonymous_variant 0.23
rpoB 761183 c.1377T>G synonymous_variant 0.14
rpoB 761222 c.1416G>C synonymous_variant 0.22
rpoB 761255 c.1449T>G synonymous_variant 0.15
rpoB 761261 c.1455G>T synonymous_variant 0.15
rpoB 761948 c.2142G>C synonymous_variant 0.13
rpoB 761954 c.2148C>G synonymous_variant 0.15
rpoB 761999 c.2193G>C synonymous_variant 0.15
rpoB 762167 c.2361T>C synonymous_variant 0.13
rpoB 762176 c.2370T>C synonymous_variant 0.13
rpoB 762185 c.2379G>C synonymous_variant 0.13
rpoB 762218 c.2412T>G synonymous_variant 0.19
rpoB 762254 c.2448T>C synonymous_variant 0.19
rpoB 762266 c.2460T>C synonymous_variant 0.19
rpoB 762284 c.2478G>C synonymous_variant 0.2
rpoB 762293 c.2487T>C synonymous_variant 0.19
rpoB 762317 c.2511A>G synonymous_variant 0.16
rpoB 762329 c.2523G>C synonymous_variant 0.17
rpoB 762338 c.2532T>C synonymous_variant 0.17
rpoC 762374 c.-996G>C upstream_gene_variant 0.13
rpoC 762380 c.-990T>G upstream_gene_variant 0.12
rpoC 762443 c.-927G>C upstream_gene_variant 0.14
rpoC 762470 c.-900G>C upstream_gene_variant 0.15
rpoB 762489 p.Val895Gln missense_variant 0.15
rpoC 762509 c.-861T>A upstream_gene_variant 0.16
rpoB 762510 p.Ala902Pro missense_variant 0.16
rpoC 763136 c.-234C>T upstream_gene_variant 0.12
rpoC 763734 p.Pro122Leu missense_variant 0.94
rpoC 763858 c.489A>G synonymous_variant 0.17
rpoC 763872 p.Gly168Ala missense_variant 0.17
rpoC 763876 p.Glu169Asp missense_variant 0.15
rpoC 763879 c.510A>G synonymous_variant 0.16
rpoC 763888 c.519G>C synonymous_variant 0.13
rpoC 763891 c.522G>C synonymous_variant 0.13
rpoC 763894 c.525A>G synonymous_variant 0.13
rpoC 763933 c.564C>T synonymous_variant 0.21
rpoC 763945 c.576T>C synonymous_variant 0.18
rpoC 763978 c.609C>G synonymous_variant 0.14
rpoC 763996 c.627T>C synonymous_variant 0.14
rpoC 764059 c.690G>C synonymous_variant 0.14
rpoC 764131 c.762T>C synonymous_variant 0.2
rpoC 764161 c.792G>C synonymous_variant 0.22
rpoC 764188 c.819A>G synonymous_variant 0.21
rpoC 764195 p.Ser276Gln missense_variant 0.17
rpoC 764203 c.834G>T synonymous_variant 0.17
rpoC 764206 c.837T>C synonymous_variant 0.17
rpoC 764257 c.888G>C synonymous_variant 0.23
rpoC 764266 c.897T>C synonymous_variant 0.21
rpoC 764269 c.900G>C synonymous_variant 0.21
rpoC 764278 c.909A>G synonymous_variant 0.15
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 0.15
rpoC 764365 c.996C>T synonymous_variant 0.13
rpoC 764387 c.1018T>C synonymous_variant 0.19
rpoC 764401 c.1032C>T synonymous_variant 0.18
rpoC 764404 c.1035C>T synonymous_variant 0.18
rpoC 764405 c.1036A>C synonymous_variant 0.24
rpoC 764419 c.1050C>T synonymous_variant 0.16
rpoC 764428 c.1059G>T synonymous_variant 0.15
rpoC 764434 c.1065A>G synonymous_variant 0.2
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.15
rpoC 764446 c.1077T>C synonymous_variant 0.2
rpoC 764451 p.Gly361Ala missense_variant 0.15
rpoC 764461 p.Glu364Asp missense_variant 0.17
rpoC 764471 p.Asn368Arg missense_variant 0.14
rpoC 764479 c.1110G>A synonymous_variant 0.14
rpoC 764498 p.Ser377Ala missense_variant 0.14
rpoC 764503 c.1134G>C synonymous_variant 0.15
rpoC 764509 c.1140G>C synonymous_variant 0.13
rpoC 764513 p.Phe382Leu missense_variant 0.13
rpoC 764521 c.1152T>C synonymous_variant 0.21
rpoC 765249 p.Leu627Ser missense_variant 0.14
rpoC 765250 c.1882_1884delAGC conservative_inframe_deletion 0.15
rpoC 765287 c.1918C>T synonymous_variant 0.14
rpoC 765292 c.1923G>T synonymous_variant 0.14
rpoC 765298 c.1929G>C synonymous_variant 0.14
rpoC 765300 p.Val644Ala missense_variant 0.14
rpoC 765319 c.1950A>G synonymous_variant 0.17
rpoC 765326 p.His653Ala missense_variant 0.15
rpoC 765330 p.Ser654Asn missense_variant 0.15
rpoC 765349 c.1980T>C synonymous_variant 0.18
rpoC 765404 p.Leu679Val missense_variant 0.12
rpoC 765412 c.2043T>C synonymous_variant 0.13
rpoC 765478 c.2109T>C synonymous_variant 0.17
rpoC 765499 c.2130C>G synonymous_variant 0.13
rpoC 765541 c.2172C>G synonymous_variant 0.17
rpoC 765553 c.2184C>T synonymous_variant 0.18
rpoC 765556 c.2187G>C synonymous_variant 0.16
rpoC 765559 c.2190G>C synonymous_variant 0.16
rpoC 765578 c.2209C>T synonymous_variant 0.18
rpoC 765583 c.2214G>T synonymous_variant 0.18
rpoC 765613 p.His748Gln missense_variant 0.19
rpoC 765625 c.2256C>G synonymous_variant 0.14
rpoC 765628 c.2259G>C synonymous_variant 0.14
rpoC 765631 p.Asp754Glu missense_variant 0.14
rpoC 765658 c.2289C>T synonymous_variant 0.18
rpoC 765700 c.2331T>C synonymous_variant 0.15
rpoC 765734 c.2365T>C synonymous_variant 0.18
rpoC 765739 c.2370G>C synonymous_variant 0.18
rpoC 765751 c.2382C>G synonymous_variant 0.2
rpoC 765753 p.Asp795Ala missense_variant 0.2
rpoC 765772 c.2403C>G synonymous_variant 0.18
rpoC 765784 c.2415C>G synonymous_variant 0.23
rpoC 765796 c.2427C>T synonymous_variant 0.17
rpoC 765814 c.2445A>G synonymous_variant 0.13
rpoC 766327 c.2958C>G synonymous_variant 0.12
rpoC 766345 c.2976T>C synonymous_variant 0.13
rpoC 766363 c.2994G>C synonymous_variant 0.13
rpoC 766381 c.3012C>T synonymous_variant 0.17
rpoC 766384 c.3015A>G synonymous_variant 0.16
rpoC 766390 c.3021C>T synonymous_variant 0.17
rpoC 766408 c.3039C>T synonymous_variant 0.17
rpoC 766426 c.3057C>T synonymous_variant 0.21
rpoC 766447 c.3078T>C synonymous_variant 0.18
rpoC 766484 p.Val1039Ile missense_variant 0.13
rpoC 766495 c.3126C>T synonymous_variant 0.13
rpoC 766522 c.3153C>G synonymous_variant 0.12
rpoC 766549 c.3180G>C synonymous_variant 0.15
rpoC 766573 c.3204T>C synonymous_variant 0.18
rpoC 766583 p.Gly1072Ser missense_variant 0.17
rpoC 766588 c.3219G>A synonymous_variant 0.15
rpoC 766594 c.3225G>C synonymous_variant 0.14
rpoC 766607 p.Ile1080Leu missense_variant 0.18
rpoC 766630 c.3261G>C synonymous_variant 0.25
rpoC 766645 c.3276A>G synonymous_variant 0.29
rpoC 766651 c.3282T>C synonymous_variant 0.22
rpoC 766657 c.3288A>G synonymous_variant 0.17
rpoC 766672 c.3303T>C synonymous_variant 0.15
rpoC 766726 c.3357T>C synonymous_variant 0.12
rpoC 766738 c.3369G>T synonymous_variant 0.19
rpoC 766750 c.3381C>G synonymous_variant 0.19
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.16
rpoC 766801 c.3432C>A synonymous_variant 0.2
rpoC 766804 c.3435A>G synonymous_variant 0.22
rpoC 766843 c.3474T>C synonymous_variant 0.19
rpoC 766861 c.3492G>C synonymous_variant 0.15
rpoC 766864 c.3495G>C synonymous_variant 0.15
mmpL5 775832 p.Ala883Ser missense_variant 0.18
mmpL5 775847 c.2634G>C synonymous_variant 0.19
mmpL5 775851 p.Ser877Thr missense_variant 0.18
mmpL5 775856 c.2625T>C synonymous_variant 0.18
mmpL5 775864 p.Ala873Ser missense_variant 0.19
mmpL5 775865 c.2616T>G synonymous_variant 0.19
mmpL5 775883 p.Ile866Leu missense_variant 0.23
mmpL5 775886 c.2595A>C synonymous_variant 0.27
mmpL5 775898 c.2583G>A synonymous_variant 0.21
mmpL5 775901 c.2580G>A synonymous_variant 0.2
mmpL5 775904 c.2577G>A synonymous_variant 0.19
mmpL5 775909 p.Leu858Phe missense_variant 0.19
mmpL5 775912 c.2569C>A synonymous_variant 0.19
mmpL5 775916 c.2565T>G synonymous_variant 0.18
mmpL5 775937 c.2544G>C synonymous_variant 0.18
mmpL5 775966 p.Ala839Ser missense_variant 0.22
mmpL5 775970 c.2511G>C synonymous_variant 0.16
rpsL 781631 c.72G>C synonymous_variant 0.17
rpsL 781649 c.90T>C synonymous_variant 0.2
rpsL 781655 c.96T>C synonymous_variant 0.2
rpsL 781682 c.123T>C synonymous_variant 0.15
rpsL 781715 c.156T>C synonymous_variant 0.17
rpsL 781728 c.169T>C synonymous_variant 0.17
rpsL 781736 c.177T>C synonymous_variant 0.18
rpsL 781751 c.192G>C synonymous_variant 0.19
rpsL 781754 c.195G>C synonymous_variant 0.19
rpsL 781760 c.201T>C synonymous_variant 0.19
rpsL 781793 c.234G>C synonymous_variant 0.18
rpsL 781832 c.273T>C synonymous_variant 0.16
rpsL 781859 c.300T>C synonymous_variant 0.16
rpsL 781868 c.309T>C synonymous_variant 0.17
rpsL 781871 c.312G>C synonymous_variant 0.18
rpsL 781892 c.333A>G synonymous_variant 0.18
rpsL 781898 c.339A>T synonymous_variant 0.17
rpsL 781916 c.357T>C synonymous_variant 0.17
rplC 800612 c.-197A>G upstream_gene_variant 0.18
rplC 800618 c.-191T>C upstream_gene_variant 0.19
rplC 800648 c.-161A>C upstream_gene_variant 0.24
rplC 800654 c.-155T>C upstream_gene_variant 0.24
rplC 800693 c.-116A>G upstream_gene_variant 0.21
rplC 800703 c.-106T>C upstream_gene_variant 0.2
rplC 800715 c.-94A>C upstream_gene_variant 0.21
rplC 800720 c.-89T>C upstream_gene_variant 0.17
rplC 800723 c.-86C>G upstream_gene_variant 0.17
rplC 800738 c.-71T>C upstream_gene_variant 0.15
rplC 800747 c.-62C>G upstream_gene_variant 0.17
rplC 800817 c.9A>T synonymous_variant 0.21
rplC 800844 c.36T>C synonymous_variant 0.27
rplC 800865 c.57A>G synonymous_variant 0.24
rplC 800867 p.Ser20Asn missense_variant 0.24
rplC 800874 c.66A>G synonymous_variant 0.24
rplC 800877 c.69A>C synonymous_variant 0.24
rplC 800880 c.72A>G synonymous_variant 0.24
rplC 800889 c.81C>G synonymous_variant 0.24
rplC 800907 c.99C>G synonymous_variant 0.27
rplC 800916 c.108A>G synonymous_variant 0.31
rplC 800937 c.129A>G synonymous_variant 0.18
rplC 800939 p.Arg44Gln missense_variant 0.18
rplC 800946 c.138T>C synonymous_variant 0.17
rplC 800949 c.141T>C synonymous_variant 0.16
rplC 800955 c.147C>G synonymous_variant 0.14
fbiC 1303995 c.1065C>T synonymous_variant 0.14
fbiC 1304001 c.1071C>G synonymous_variant 0.17
fbiC 1304008 c.1078T>C synonymous_variant 0.15
fbiC 1304049 c.1119T>G synonymous_variant 0.13
fbiC 1304058 c.1128G>A synonymous_variant 0.2
fbiC 1304059 c.1129C>T synonymous_variant 0.13
fbiC 1304634 c.1704C>G synonymous_variant 0.12
fbiC 1304640 c.1710A>C synonymous_variant 0.13
fbiC 1304691 c.1761G>C synonymous_variant 0.15
fbiC 1304703 c.1773C>G synonymous_variant 0.21
fbiC 1304715 c.1785G>C synonymous_variant 0.27
fbiC 1304724 c.1794A>G synonymous_variant 0.25
fbiC 1304727 c.1797A>G synonymous_variant 0.22
fbiC 1304742 c.1812T>C synonymous_variant 0.21
fbiC 1304748 c.1818T>C synonymous_variant 0.21
fbiC 1304754 c.1824G>A synonymous_variant 0.2
fbiC 1304757 c.1827A>G synonymous_variant 0.2
fbiC 1304784 c.1854T>C synonymous_variant 0.2
fbiC 1304787 c.1857T>C synonymous_variant 0.21
fbiC 1304790 c.1860C>G synonymous_variant 0.2
fbiC 1304808 c.1878C>G synonymous_variant 0.19
fbiC 1304811 c.1881C>G synonymous_variant 0.19
fbiC 1304817 c.1887T>C synonymous_variant 0.19
fbiC 1304829 c.1899T>C synonymous_variant 0.16
fbiC 1304832 c.1902C>G synonymous_variant 0.2
fbiC 1304853 c.1923C>G synonymous_variant 0.17
fbiC 1304856 c.1926C>G synonymous_variant 0.17
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 0.16
fbiC 1304877 c.1947T>C synonymous_variant 0.16
fbiC 1304878 c.1948_1950delCGCinsAGG synonymous_variant 0.16
fbiC 1304893 p.Gly655Ser missense_variant 0.17
fbiC 1304940 c.2010A>G synonymous_variant 0.14
fbiC 1304958 c.2028T>G synonymous_variant 0.14
atpE 1461150 p.Ile36Val missense_variant 0.19
atpE 1461194 c.150C>T synonymous_variant 0.13
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.14
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.28
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.25
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.26
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.22
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.25
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.21
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.23
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.22
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.2
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.2
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.21
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.21
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.22
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.23
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.22
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.22
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.2
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.21
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.22
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.2
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.25
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.21
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.21
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.14
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.18
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.18
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.24
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.24
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.24
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.24
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.2
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.17
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.2
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.13
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.14
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.14
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.14
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.14
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.12
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.12
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.13
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.13
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.17
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.17
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.14
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.61
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.63
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.63
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.63
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.65
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.71
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.71
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.71
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.7
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.7
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.72
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.73
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.72
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.72
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.71
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.72
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.67
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.67
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.67
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.66
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.37
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.15
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.12
rrl 1476640 n.2983C>A non_coding_transcript_exon_variant 0.87
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.12
rpsA 1834366 c.825A>G synonymous_variant 0.16
rpsA 1834375 c.834G>A synonymous_variant 0.15
rpsA 1834396 c.855G>C synonymous_variant 0.17
rpsA 1834411 c.870T>C synonymous_variant 0.17
rpsA 1834417 c.876G>C synonymous_variant 0.21
rpsA 1834423 c.882G>C synonymous_variant 0.21
rpsA 1834435 c.894G>C synonymous_variant 0.23
rpsA 1834451 c.910T>C synonymous_variant 0.17
rpsA 1834465 c.924T>C synonymous_variant 0.22
rpsA 1834468 c.927A>G synonymous_variant 0.22
rpsA 1834474 c.933C>G synonymous_variant 0.23
rpsA 1834489 c.948T>C synonymous_variant 0.26
rpsA 1834498 c.957C>T synonymous_variant 0.25
rpsA 1834528 c.987T>C synonymous_variant 0.21
rpsA 1834546 c.1005T>C synonymous_variant 0.21
rpsA 1834555 c.1014T>C synonymous_variant 0.22
rpsA 1834558 c.1017C>G synonymous_variant 0.21
rpsA 1834606 c.1065C>G synonymous_variant 0.29
rpsA 1834609 c.1068T>C synonymous_variant 0.27
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.25
rpsA 1834633 c.1092A>G synonymous_variant 0.21
rpsA 1834639 c.1098T>C synonymous_variant 0.21
rpsA 1834666 c.1125G>C synonymous_variant 0.17
rpsA 1834669 c.1128G>C synonymous_variant 0.15
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.18
rpsA 1834732 c.1191T>C synonymous_variant 0.2
rpsA 1834733 p.Ala398Pro missense_variant 0.2
rpsA 1834753 c.1212T>C synonymous_variant 0.2
tlyA 1918034 p.Val32Ala missense_variant 1.0
katG 2155918 p.Ala65Val missense_variant 1.0
PPE35 2168767 p.Ser616Gly missense_variant 1.0
Rv1979c 2222377 p.Val263Gly missense_variant 1.0
kasA 2517947 c.-168C>T upstream_gene_variant 0.24
kasA 2517974 c.-141T>C upstream_gene_variant 0.18
kasA 2517989 c.-126T>C upstream_gene_variant 0.17
kasA 2517992 c.-123C>G upstream_gene_variant 0.17
kasA 2517998 c.-117C>T upstream_gene_variant 0.17
kasA 2518019 c.-96A>G upstream_gene_variant 0.17
kasA 2518025 c.-90G>C upstream_gene_variant 0.22
folC 2747355 p.Val82Ile missense_variant 0.14
folC 2747359 c.240C>G synonymous_variant 0.14
folC 2747362 c.237G>C synonymous_variant 0.14
ribD 2986993 p.Gly52Val missense_variant 1.0
Rv2752c 3065787 c.405G>C synonymous_variant 1.0
thyA 3074001 c.471C>G synonymous_variant 0.14
thyA 3074010 c.462C>G synonymous_variant 0.18
thyA 3074031 c.441T>C synonymous_variant 0.18
thyA 3074037 c.435C>G synonymous_variant 0.18
thyA 3074056 p.Glu139Pro missense_variant 0.19
thyA 3074061 c.411A>G synonymous_variant 0.19
thyA 3074076 c.396C>G synonymous_variant 0.18
thyA 3074097 c.375C>G synonymous_variant 0.18
thyA 3074100 c.372T>C synonymous_variant 0.18
thyA 3074106 c.366T>C synonymous_variant 0.17
thyA 3074117 c.355C>T synonymous_variant 0.17
thyA 3074120 c.352T>C synonymous_variant 0.17
thyA 3074130 c.342G>C synonymous_variant 0.16
Rv3083 3448649 p.Arg49Pro missense_variant 1.0
fprA 3473812 c.-195G>A upstream_gene_variant 0.12
Rv3236c 3613067 p.Val17Gly missense_variant 1.0
Rv3236c 3613315 c.-199T>G upstream_gene_variant 1.0
fbiA 3640435 c.-108A>C upstream_gene_variant 1.0
fbiB 3642614 c.1080C>T synonymous_variant 0.2
fbiB 3642620 c.1086T>C synonymous_variant 0.19
fbiB 3642656 c.1122G>C synonymous_variant 0.2
fbiB 3642659 c.1125C>G synonymous_variant 0.17
fbiB 3642662 c.1128C>G synonymous_variant 0.18
fbiB 3642668 c.1134A>C synonymous_variant 0.25
fbiB 3642677 c.1143A>G synonymous_variant 0.13
fbiB 3642696 c.1162C>T synonymous_variant 0.13
fbiB 3642734 c.1200G>C synonymous_variant 0.14
fbiB 3642743 c.1209T>C synonymous_variant 0.14
clpC1 4038308 p.Val799Ile missense_variant 0.14
clpC1 4038317 c.2388G>C synonymous_variant 0.18
clpC1 4038398 c.2307G>T synonymous_variant 0.12
clpC1 4038740 c.1965G>C synonymous_variant 0.14
clpC1 4038748 p.Arg653Cys missense_variant 0.14
clpC1 4038851 c.1854G>A synonymous_variant 0.19
clpC1 4038908 c.1797C>G synonymous_variant 0.14
clpC1 4038914 c.1791G>C synonymous_variant 0.14
clpC1 4038923 c.1782A>G synonymous_variant 0.14
clpC1 4038956 c.1749T>C synonymous_variant 0.15
clpC1 4038965 c.1740T>C synonymous_variant 0.14
clpC1 4039517 c.1188C>G synonymous_variant 0.16
clpC1 4039553 c.1152C>G synonymous_variant 0.12
clpC1 4039610 c.1095G>C synonymous_variant 0.2
clpC1 4039616 c.1089G>C synonymous_variant 0.2
clpC1 4039622 c.1083C>G synonymous_variant 0.19
clpC1 4039682 c.1023C>G synonymous_variant 0.14
clpC1 4039685 c.1020C>T synonymous_variant 0.14
clpC1 4039694 c.1011G>C synonymous_variant 0.14
clpC1 4039724 c.981A>G synonymous_variant 0.14
clpC1 4039748 c.957G>C synonymous_variant 0.17
clpC1 4039751 c.954A>G synonymous_variant 0.15
clpC1 4039757 c.948A>G synonymous_variant 0.15
clpC1 4039842 c.862_863insT frameshift_variant 0.91
clpC1 4039898 c.807C>G synonymous_variant 0.2
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.17
clpC1 4039931 c.774T>C synonymous_variant 0.18
clpC1 4039946 c.759A>T synonymous_variant 0.18
clpC1 4039952 c.753T>C synonymous_variant 0.19
clpC1 4039958 c.747G>C synonymous_variant 0.19
clpC1 4039979 c.726C>G synonymous_variant 0.18
clpC1 4039996 p.Glu237Gln missense_variant 0.19
clpC1 4040021 c.684A>C synonymous_variant 0.21
clpC1 4040024 c.681A>G synonymous_variant 0.21
clpC1 4040033 c.672G>C synonymous_variant 0.17
clpC1 4040036 c.669C>G synonymous_variant 0.17
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.17
clpC1 4040093 c.612C>G synonymous_variant 0.18
clpC1 4040105 c.600C>G synonymous_variant 0.16
clpC1 4040153 c.552A>G synonymous_variant 0.16
clpC1 4040201 c.504C>G synonymous_variant 0.18
clpC1 4040207 c.498T>C synonymous_variant 0.12
clpC1 4040215 p.Ser164Thr missense_variant 0.12
clpC1 4040225 c.480A>C synonymous_variant 0.14
clpC1 4040228 c.477G>C synonymous_variant 0.14
clpC1 4040234 c.471C>G synonymous_variant 0.13
clpC1 4040237 c.468C>T synonymous_variant 0.12
clpC1 4040249 c.456A>G synonymous_variant 0.18
clpC1 4040273 c.432T>C synonymous_variant 0.21
clpC1 4040354 c.351A>G synonymous_variant 0.25
clpC1 4040363 c.342A>C synonymous_variant 0.27
clpC1 4040369 c.336C>G synonymous_variant 0.25
clpC1 4040380 c.325T>C synonymous_variant 0.21
clpC1 4040381 c.324T>C synonymous_variant 0.21
clpC1 4040387 c.318A>G synonymous_variant 0.25
clpC1 4040393 c.312G>C synonymous_variant 0.17
clpC1 4040411 c.294T>C synonymous_variant 0.25
clpC1 4040423 c.282A>G synonymous_variant 0.23
clpC1 4040426 c.279T>C synonymous_variant 0.23
clpC1 4040431 c.274T>C synonymous_variant 0.21
clpC1 4040441 c.264C>G synonymous_variant 0.18
clpC1 4040444 c.261C>G synonymous_variant 0.18
panD 4044103 p.Ile60Ser missense_variant 1.0
embA 4244298 p.Ser356Ala missense_variant 0.12
embA 4244309 c.1077C>G synonymous_variant 0.13
embA 4244312 c.1080T>G synonymous_variant 0.13
embA 4244315 c.1083G>C synonymous_variant 0.15
embA 4244324 c.1092T>G synonymous_variant 0.17
embA 4244327 c.1095T>C synonymous_variant 0.18
embA 4244337 p.Leu369Val missense_variant 0.17
embA 4244340 p.Ser370Ala missense_variant 0.17
embA 4244366 c.1134C>G synonymous_variant 0.2
embA 4244372 c.1140T>G synonymous_variant 0.17
embA 4244378 c.1146G>A synonymous_variant 0.17
embA 4245031 p.Arg600Gln missense_variant 1.0
embB 4247773 c.1260G>A synonymous_variant 0.15
embB 4247776 c.1263G>T synonymous_variant 0.13
embB 4247779 c.1266C>G synonymous_variant 0.13
embB 4247819 p.Val436Ile missense_variant 0.12
embB 4247836 c.1323A>G synonymous_variant 0.14
embB 4247842 c.1329T>C synonymous_variant 0.14
embB 4247876 c.1363C>T synonymous_variant 0.17
embB 4247986 c.1473C>G synonymous_variant 0.17
embB 4248007 c.1494C>G synonymous_variant 0.17
embB 4248011 p.Ser500Ala missense_variant 0.17
gid 4408218 c.-16G>T upstream_gene_variant 1.0