TB-Profiler result

Run: SRR13861492
Summary

Run ID: SRR13861492

Sample name:

Date: 03-04-2023 09:33:03

Number of reads: 1757069

Percentage reads mapped: 35.18

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5624 p.Asn129Asp missense_variant 1.0
mshA 575194 c.-154G>T upstream_gene_variant 1.0
rpoB 760907 c.1101_1102insT frameshift_variant 1.0
rplC 801226 p.Gly140Arg missense_variant 1.0
embR 1417503 c.-156A>C upstream_gene_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.16
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.16
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.16
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.16
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.16
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.16
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.16
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.16
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.16
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.16
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.16
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.16
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.15
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.15
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.14
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.15
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.17
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.12
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.11
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.37
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.48
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.48
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.46
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.47
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.53
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.53
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.53
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.53
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.53
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.54
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.53
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.53
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.53
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.56
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.55
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.51
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.52
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.49
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.5
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.2
rrl 1476753 n.3099delG non_coding_transcript_exon_variant 1.0
fabG1 1673233 c.-207T>G upstream_gene_variant 1.0
rpsA 1833593 c.53delC frameshift_variant 1.0
rpsA 1834884 p.Gln448Leu missense_variant 1.0
PPE35 2169282 p.Arg444His missense_variant 1.0
ahpC 2725932 c.-261G>A upstream_gene_variant 1.0
pepQ 2859739 p.Ala227Gly missense_variant 1.0
pepQ 2860197 c.222T>C synonymous_variant 1.0
Rv3083 3448909 p.Leu136Ile missense_variant 0.98
fbiA 3640691 p.Asp50Val missense_variant 1.0
fbiA 3641204 p.Gly221Asp missense_variant 1.0
clpC1 4039961 p.Tyr248* stop_gained 1.0
embC 4240818 p.Thr319Arg missense_variant 1.0
embB 4248081 c.1569dupG frameshift_variant 1.0
ethA 4327644 c.-171G>A upstream_gene_variant 1.0