TB-Profiler result

Run: SRR13861549
Summary

Run ID: SRR13861549

Sample name:

Date: 03-04-2023 09:34:37

Number of reads: 233694

Percentage reads mapped: 5.85

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761131 p.Gly442Glu missense_variant 0.2 rifampicin
rrs 1472122 n.277G>C non_coding_transcript_exon_variant 0.83 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5319 p.Arg27Leu missense_variant 1.0
gyrA 6949 c.-353A>G upstream_gene_variant 0.18
gyrA 7595 c.294C>G synonymous_variant 0.29
gyrA 7607 c.306C>G synonymous_variant 0.38
gyrA 7626 c.325C>T synonymous_variant 0.33
gyrA 7631 c.330G>C synonymous_variant 0.33
gyrA 7637 c.336C>G synonymous_variant 0.38
gyrA 7649 c.348C>T synonymous_variant 0.22
gyrA 7652 c.351C>T synonymous_variant 0.22
gyrA 7658 c.357A>G synonymous_variant 0.2
gyrA 7664 c.363T>C synonymous_variant 0.2
gyrA 7670 c.369A>G synonymous_variant 0.18
gyrA 7676 c.375G>C synonymous_variant 0.18
gyrA 7683 c.382A>C synonymous_variant 0.18
gyrA 7694 c.393A>G synonymous_variant 0.18
gyrA 7697 c.396C>G synonymous_variant 0.18
gyrA 7710 c.409T>C synonymous_variant 0.17
gyrA 7715 c.414G>C synonymous_variant 0.18
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.2
gyrA 8786 c.1485T>C synonymous_variant 0.2
gyrA 8796 p.Ile499Val missense_variant 0.18
gyrA 8801 c.1500G>C synonymous_variant 0.2
gyrA 8810 c.1509A>C synonymous_variant 0.2
gyrA 8816 c.1515C>T synonymous_variant 0.2
gyrA 8829 c.1528T>C synonymous_variant 0.2
gyrA 8837 c.1536C>T synonymous_variant 0.2
gyrA 8852 c.1551T>C synonymous_variant 0.2
gyrA 8858 c.1557T>C synonymous_variant 0.2
gyrA 8867 c.1566A>G synonymous_variant 0.2
gyrA 8870 c.1569G>C synonymous_variant 0.18
gyrA 8873 c.1572A>C synonymous_variant 0.18
gyrA 8897 c.1596T>C synonymous_variant 0.2
gyrA 8903 c.1602T>C synonymous_variant 0.22
gyrA 8915 c.1614A>G synonymous_variant 0.22
rpoB 760867 p.Gly354Asp missense_variant 1.0
rpoB 761126 c.1320G>T synonymous_variant 0.2
rpoB 761129 c.1323G>C synonymous_variant 0.2
rpoB 761133 p.Leu443Ile missense_variant 0.25
rpoB 761150 c.1344A>C synonymous_variant 0.38
rpoB 761151 p.Leu449Val missense_variant 0.25
rpoB 761156 c.1350G>C synonymous_variant 0.25
rpoB 761162 c.1356G>C synonymous_variant 0.22
rpoB 761165 c.1359G>C synonymous_variant 0.38
rpoB 761168 c.1362C>G synonymous_variant 0.38
rpoB 761178 p.Ser458Thr missense_variant 0.25
rpoB 761192 c.1386C>G synonymous_variant 0.33
rpoB 761195 c.1389G>C synonymous_variant 0.33
rpoB 761196 p.Leu464Phe missense_variant 0.33
rpoB 761204 c.1398C>T synonymous_variant 0.25
rpoB 761207 c.1401C>T synonymous_variant 0.25
rpoB 761213 c.1407G>A synonymous_variant 0.29
rpoB 761220 p.Ser472Thr missense_variant 0.25
rpoB 761234 c.1428G>C synonymous_variant 0.22
rpoB 761235 p.Met477Val missense_variant 0.22
rpoB 761657 c.1851C>G synonymous_variant 0.15
rpoB 761765 c.1959T>C synonymous_variant 0.17
rpoB 761772 p.His656Ala missense_variant 0.2
rpoB 761778 p.Asn658Asp missense_variant 0.2
rpoB 761791 p.Arg662His missense_variant 0.25
rpoB 761813 c.2007T>C synonymous_variant 0.17
rpoB 761815 p.Ala670Glu missense_variant 0.17
rpoB 761834 c.2028T>C synonymous_variant 0.23
rpoB 761847 p.Cys681Ser missense_variant 0.23
rpoB 761852 c.2046C>G synonymous_variant 0.23
rpoB 761858 c.2052G>C synonymous_variant 0.25
rpoB 761864 c.2058G>C synonymous_variant 0.25
rpoB 761873 c.2067A>G synonymous_variant 0.23
rpoB 761885 c.2079T>C synonymous_variant 0.21
rpoB 761891 c.2085G>C synonymous_variant 0.21
rpoB 761906 c.2100C>G synonymous_variant 0.21
rpoB 761912 c.2106T>C synonymous_variant 0.15
rpoB 761915 p.Asp703Glu missense_variant 0.15
rpoB 761916 p.Asp704Asn missense_variant 0.15
rpoB 762053 c.2247T>C synonymous_variant 0.18
rpoB 762062 c.2256T>C synonymous_variant 0.18
rpoB 762065 c.2259T>C synonymous_variant 0.18
rpoB 762083 c.2277T>C synonymous_variant 0.2
rpoB 762086 c.2280G>C synonymous_variant 0.2
rpoB 762101 c.2295C>G synonymous_variant 0.27
rpoB 762114 p.Ile770Val missense_variant 0.43
rpoB 762131 c.2325C>G synonymous_variant 0.29
rpoB 762143 c.2337T>C synonymous_variant 0.21
rpoB 762149 c.2343G>C synonymous_variant 0.2
rpoB 762167 c.2361T>C synonymous_variant 0.21
rpoB 762176 c.2370T>C synonymous_variant 0.23
rpoB 762185 c.2379G>C synonymous_variant 0.25
rpoB 762218 c.2412T>G synonymous_variant 0.22
rpoB 762254 c.2448T>C synonymous_variant 0.27
rpoB 762266 c.2460T>C synonymous_variant 0.18
rpoB 762284 c.2478G>C synonymous_variant 0.15
rpoB 762293 c.2487T>C synonymous_variant 0.17
rpoB 762317 c.2511A>G synonymous_variant 0.23
rpoB 762329 c.2523G>C synonymous_variant 0.23
rpoB 762338 c.2532T>C synonymous_variant 0.23
rpoB 762347 c.2541T>C synonymous_variant 0.23
rpoB 762362 p.Glu852Asp missense_variant 0.2
rpoB 762369 c.2563T>C synonymous_variant 0.19
rpoC 762443 c.-927G>C upstream_gene_variant 0.13
rpoB 762496 c.2691delC frameshift_variant 0.93
rpoC 763028 c.-342T>C upstream_gene_variant 0.33
rpoC 763031 c.-339T>G upstream_gene_variant 0.29
rpoC 763034 c.-336C>G upstream_gene_variant 0.29
rpoC 763040 c.-330C>G upstream_gene_variant 0.44
rpoC 763070 c.-300T>C upstream_gene_variant 0.3
rpoC 763076 c.-294C>G upstream_gene_variant 0.3
rpoC 763085 c.-285C>G upstream_gene_variant 0.3
rpoC 763115 c.-255T>C upstream_gene_variant 0.33
rpoC 763136 c.-234C>T upstream_gene_variant 0.3
rpoC 763148 c.-222G>C upstream_gene_variant 0.27
rpoC 763158 c.-212C>T upstream_gene_variant 0.27
rpoC 763166 c.-204A>G upstream_gene_variant 0.3
rpoC 763169 c.-201A>G upstream_gene_variant 0.3
rpoC 764387 c.1018T>C synonymous_variant 0.31
rpoC 764401 c.1032C>T synonymous_variant 0.44
rpoC 764404 c.1035C>T synonymous_variant 0.44
rpoC 764405 c.1036A>C synonymous_variant 0.44
rpoC 764419 c.1050C>T synonymous_variant 0.44
rpoC 764428 c.1059G>T synonymous_variant 0.47
rpoC 764434 c.1065A>G synonymous_variant 0.47
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.5
rpoC 764441 p.Ile358Leu missense_variant 0.5
rpoC 764446 c.1077T>C synonymous_variant 0.54
rpoC 764451 p.Gly361Ala missense_variant 0.54
rpoC 764455 c.1086G>T synonymous_variant 0.54
rpoC 764461 p.Glu364Asp missense_variant 0.54
rpoC 764470 c.1101C>G synonymous_variant 0.54
rpoC 764471 p.Asn368Arg missense_variant 0.54
rpoC 764479 c.1110G>A synonymous_variant 0.54
rpoC 764485 c.1116G>C synonymous_variant 0.54
rpoC 764498 p.Ser377Ala missense_variant 0.54
rpoC 764503 c.1134G>C synonymous_variant 0.54
rpoC 764509 c.1140G>C synonymous_variant 0.5
rpoC 764513 p.Phe382Leu missense_variant 0.5
rpoC 764521 c.1152T>C synonymous_variant 0.46
rpoC 764527 c.1158C>T synonymous_variant 0.3
rpoC 766563 p.Thr1065Ser missense_variant 1.0
rpoC 766933 c.3564A>G synonymous_variant 0.18
rpoC 766945 c.3576A>G synonymous_variant 0.18
rpoC 766963 c.3594T>C synonymous_variant 0.18
rpoC 766978 c.3609C>G synonymous_variant 0.18
rpoC 766996 c.3627C>T synonymous_variant 0.2
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.2
rpoC 767014 c.3645G>C synonymous_variant 0.17
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.18
rpoC 767059 c.3690T>G synonymous_variant 0.18
rpoC 767062 c.3693C>A synonymous_variant 0.18
rpoC 767074 c.3705T>C synonymous_variant 0.25
rpoC 767098 c.3729T>C synonymous_variant 0.18
rpoC 767119 c.3750A>G synonymous_variant 0.17
rpoC 767158 c.3789T>C synonymous_variant 0.19
rpoC 767167 c.3798C>G synonymous_variant 0.21
mmpL5 775976 c.2505G>C synonymous_variant 1.0
mmpL5 776814 p.Gln556Arg missense_variant 1.0
rplC 800623 c.-186A>C upstream_gene_variant 0.91
rplC 800769 c.-40A>T upstream_gene_variant 0.67
fbiC 1302878 c.-53C>G upstream_gene_variant 1.0
fbiC 1303535 p.Ser202Leu missense_variant 1.0
fbiC 1304703 c.1773C>G synonymous_variant 0.25
fbiC 1304715 c.1785G>C synonymous_variant 0.25
fbiC 1304724 c.1794A>G synonymous_variant 0.25
fbiC 1304727 c.1797A>G synonymous_variant 0.25
fbiC 1304742 c.1812T>C synonymous_variant 0.29
fbiC 1304748 c.1818T>C synonymous_variant 0.33
fbiC 1304754 c.1824G>A synonymous_variant 0.29
fbiC 1304757 c.1827A>G synonymous_variant 0.33
fbiC 1304784 c.1854T>C synonymous_variant 0.4
fbiC 1304787 c.1857T>C synonymous_variant 0.4
fbiC 1304790 c.1860C>G synonymous_variant 0.4
fbiC 1304808 c.1878C>G synonymous_variant 0.67
fbiC 1304811 c.1881C>G synonymous_variant 0.5
fbiC 1304817 c.1887T>C synonymous_variant 0.5
fbiC 1304829 c.1899T>C synonymous_variant 0.4
fbiC 1304832 c.1902C>G synonymous_variant 0.4
atpE 1461132 p.Val30Ile missense_variant 0.33
atpE 1461149 c.105T>G synonymous_variant 0.25
atpE 1461150 p.Ile36Val missense_variant 0.25
atpE 1461185 c.141G>C synonymous_variant 0.25
atpE 1461189 c.145C>T synonymous_variant 0.25
atpE 1461194 c.150C>T synonymous_variant 0.25
atpE 1461197 c.153A>G synonymous_variant 0.25
atpE 1461219 c.175T>C synonymous_variant 0.25
atpE 1461224 c.180T>C synonymous_variant 0.25
atpE 1461233 c.189A>G synonymous_variant 0.29
atpE 1461256 p.Met71Arg missense_variant 0.8
rrs 1471836 n.-10A>G upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.33
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.4
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.2
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.2
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.57
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.63
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.63
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.63
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.63
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.63
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.57
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.5
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.55
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.59
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.55
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.55
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.57
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.57
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.57
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.57
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.52
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.33
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.31
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.23
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.23
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.23
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.25
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.25
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.29
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.25
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.22
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.22
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.22
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.2
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.2
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.2
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.2
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.22
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.22
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.2
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.2
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.25
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.25
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.25
rrl 1474434 n.777T>G non_coding_transcript_exon_variant 0.22
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.2
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.31
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.87
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.86
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.86
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.84
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.84
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.88
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.89
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.9
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.9
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.9
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.88
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.88
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.88
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.86
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.86
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.86
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.85
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.86
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.85
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.85
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.59
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.42
inhA 1674231 c.30T>C synonymous_variant 0.22
inhA 1674237 c.36T>C synonymous_variant 0.2
inhA 1674239 p.Ser13Thr missense_variant 0.2
inhA 1674243 c.42A>G synonymous_variant 0.2
inhA 1674279 c.78A>C synonymous_variant 0.14
inhA 1674281 p.Arg27Gln missense_variant 0.14
inhA 1674537 c.336C>G synonymous_variant 0.18
inhA 1674542 p.Ala114Glu missense_variant 0.18
inhA 1674549 c.348G>C synonymous_variant 0.17
inhA 1674555 c.354G>A synonymous_variant 0.2
inhA 1674561 c.360C>T synonymous_variant 0.2
inhA 1674564 c.363C>T synonymous_variant 0.25
inhA 1674582 c.381T>C synonymous_variant 0.29
inhA 1674585 c.384T>C synonymous_variant 0.29
inhA 1674589 p.Met130Leu missense_variant 0.29
inhA 1674624 c.423A>C synonymous_variant 0.4
inhA 1674627 c.426T>G synonymous_variant 0.4
inhA 1674630 c.429C>G synonymous_variant 0.4
inhA 1674636 c.435C>G synonymous_variant 0.43
inhA 1674654 c.453G>C synonymous_variant 0.29
rpsA 1833595 c.54T>C synonymous_variant 0.22
rpsA 1833619 c.78A>C synonymous_variant 0.22
rpsA 1833661 c.120A>G synonymous_variant 0.27
rpsA 1833667 c.126C>G synonymous_variant 0.25
rpsA 1833724 c.183C>G synonymous_variant 0.27
rpsA 1833727 c.186G>C synonymous_variant 0.33
rpsA 1833742 c.201A>G synonymous_variant 0.25
rpsA 1833745 c.204G>C synonymous_variant 0.25
rpsA 1833787 c.246C>G synonymous_variant 0.29
rpsA 1833790 c.249T>A synonymous_variant 0.31
rpsA 1833799 c.258C>G synonymous_variant 0.25
rpsA 1833811 c.270G>C synonymous_variant 0.31
rpsA 1833838 c.297G>C synonymous_variant 0.33
rpsA 1833841 c.300C>G synonymous_variant 0.33
rpsA 1833847 c.306C>G synonymous_variant 0.33
rpsA 1833856 c.315A>G synonymous_variant 0.36
rpsA 1833862 c.321G>T synonymous_variant 0.42
rpsA 1833874 c.333T>C synonymous_variant 0.38
rpsA 1833928 c.387G>C synonymous_variant 0.33
rpsA 1833940 c.399C>G synonymous_variant 0.36
rpsA 1833970 c.429G>C synonymous_variant 0.27
rpsA 1833979 c.438T>C synonymous_variant 0.33
rpsA 1834000 c.459G>C synonymous_variant 0.33
rpsA 1834015 c.474G>C synonymous_variant 0.22
rpsA 1834021 c.480C>T synonymous_variant 0.22
rpsA 1834417 c.876G>C synonymous_variant 0.18
rpsA 1834423 c.882G>C synonymous_variant 0.2
rpsA 1834435 c.894G>C synonymous_variant 0.18
rpsA 1834528 c.987T>C synonymous_variant 0.15
rpsA 1834546 c.1005T>C synonymous_variant 0.14
rpsA 1834555 c.1014T>C synonymous_variant 0.14
rpsA 1834558 c.1017C>G synonymous_variant 0.15
katG 2155722 c.390G>C synonymous_variant 0.33
katG 2155740 p.Gly124Gln missense_variant 0.33
katG 2155747 p.Ala122Gly missense_variant 0.33
katG 2156157 c.-46C>A upstream_gene_variant 1.0
PPE35 2168627 p.Ile662Met missense_variant 1.0
Rv1979c 2222100 c.1065T>A synonymous_variant 1.0
pncA 2289242 c.-1T>C upstream_gene_variant 1.0
kasA 2518138 c.24T>C synonymous_variant 0.33
kasA 2518146 p.Phe11Tyr missense_variant 0.29
kasA 2518162 c.48G>A synonymous_variant 0.29
kasA 2518174 c.60A>G synonymous_variant 0.29
kasA 2518190 p.Ser26Ala missense_variant 0.29
kasA 2518199 p.Ile29Val missense_variant 0.25
kasA 2518222 c.108G>A synonymous_variant 0.22
kasA 2518223 c.109_111delTTGinsCTC synonymous_variant 0.22
kasA 2518234 c.120G>A synonymous_variant 0.2
kasA 2518248 p.Ala45Val missense_variant 0.22
kasA 2518540 c.426T>G synonymous_variant 0.17
kasA 2518768 c.654C>G synonymous_variant 0.17
kasA 2518783 c.669T>C synonymous_variant 0.2
kasA 2518792 c.678C>G synonymous_variant 0.2
kasA 2518795 c.681C>G synonymous_variant 0.2
kasA 2518822 c.708C>G synonymous_variant 0.25
kasA 2518825 c.711T>C synonymous_variant 0.25
kasA 2518843 c.729T>C synonymous_variant 0.29
folC 2747317 c.282C>G synonymous_variant 0.18
folC 2747355 p.Val82Ile missense_variant 0.27
folC 2747359 c.240C>G synonymous_variant 0.25
folC 2747362 c.237G>C synonymous_variant 0.25
folC 2747394 p.Ile69Val missense_variant 0.18
folC 2747395 c.204T>C synonymous_variant 0.17
folC 2747407 c.192T>C synonymous_variant 0.17
folC 2747411 p.Ser63Ala missense_variant 0.2
folC 2747416 c.183A>G synonymous_variant 0.2
folC 2747419 c.180C>G synonymous_variant 0.2
folC 2747430 c.169C>T synonymous_variant 0.2
folC 2747439 p.Met54Leu missense_variant 0.18
folC 2747442 c.157T>C synonymous_variant 0.18
folC 2747443 c.156G>A synonymous_variant 0.18
folC 2747464 c.135G>C synonymous_variant 0.2
ribD 2987205 p.Ser123Ala missense_variant 1.0
ribD 2987347 p.Pro170Leu missense_variant 1.0
Rv2752c 3064980 c.1212C>G synonymous_variant 0.5
Rv3083 3448903 p.Asp134His missense_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.29
fprA 3473812 c.-195G>A upstream_gene_variant 0.29
fprA 3473836 c.-171C>A upstream_gene_variant 0.33
fprA 3473843 c.-164C>G upstream_gene_variant 0.29
Rv3236c 3612621 c.496T>C synonymous_variant 0.18
Rv3236c 3612628 c.489G>C synonymous_variant 0.18
Rv3236c 3612643 c.474A>G synonymous_variant 0.18
Rv3236c 3612667 c.450T>G synonymous_variant 0.18
Rv3236c 3612673 c.444G>C synonymous_variant 0.17
Rv3236c 3612676 c.441A>G synonymous_variant 0.17
Rv3236c 3612685 c.432C>T synonymous_variant 0.17
Rv3236c 3612694 p.Arg141His missense_variant 0.17
Rv3236c 3612708 c.409T>C synonymous_variant 0.18
Rv3236c 3612715 c.402G>C synonymous_variant 0.15
Rv3236c 3612721 c.396G>C synonymous_variant 0.18
Rv3236c 3612724 c.393T>C synonymous_variant 0.18
Rv3236c 3612730 c.387C>G synonymous_variant 0.15
Rv3236c 3612748 c.369G>C synonymous_variant 0.15
rpoA 3877515 c.993G>C synonymous_variant 0.18
rpoA 3877542 c.966C>T synonymous_variant 0.18
rpoA 3877553 p.Glu319Gln missense_variant 0.2
rpoA 3877557 c.951C>G synonymous_variant 0.18
rpoA 3877587 c.921A>G synonymous_variant 0.2
rpoA 3877613 p.Ile299Val missense_variant 0.22
rpoA 3877638 c.870T>C synonymous_variant 0.17
rpoA 3878118 c.390T>C synonymous_variant 0.29
clpC1 4038293 c.2412G>C synonymous_variant 0.25
clpC1 4038302 c.2403C>G synonymous_variant 0.25
clpC1 4038308 p.Val799Ile missense_variant 0.22
clpC1 4038317 c.2388G>C synonymous_variant 0.25
clpC1 4038388 c.2317T>C synonymous_variant 0.29
clpC1 4038398 c.2307G>T synonymous_variant 0.25
clpC1 4038403 c.2302T>C synonymous_variant 0.29
clpC1 4038419 c.2286T>C synonymous_variant 0.25
clpC1 4038434 c.2271G>C synonymous_variant 0.38
clpC1 4038444 p.Ala754Lys missense_variant 0.33
clpC1 4038446 c.2259T>C synonymous_variant 0.33
clpC1 4038452 c.2253G>C synonymous_variant 0.33
clpC1 4038461 p.Ala748Asp missense_variant 0.4
clpC1 4038498 p.Ser736Thr missense_variant 0.4
clpC1 4038530 p.Glu725Asp missense_variant 0.4
clpC1 4038536 c.2169C>T synonymous_variant 0.4
clpC1 4039484 c.1221T>G synonymous_variant 0.18
clpC1 4039663 p.Gly348Ser missense_variant 1.0
clpC1 4040021 c.684A>C synonymous_variant 0.29
clpC1 4040024 c.681A>G synonymous_variant 0.29
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.33
clpC1 4040093 c.612C>G synonymous_variant 0.33
clpC1 4040105 c.600C>G synonymous_variant 0.33
embC 4240204 c.342T>C synonymous_variant 0.2
embC 4240210 c.348C>G synonymous_variant 0.2
embC 4240216 c.354T>C synonymous_variant 0.2
embC 4240258 c.396T>G synonymous_variant 0.25
embC 4240267 c.405T>C synonymous_variant 0.25
embC 4240270 c.408T>C synonymous_variant 0.25
embC 4240277 p.Leu139Val missense_variant 0.29
embC 4240282 c.420C>G synonymous_variant 0.29
embC 4240285 c.423C>G synonymous_variant 0.29
embC 4240780 c.918T>C synonymous_variant 0.22
embC 4240783 c.921G>C synonymous_variant 0.22
embC 4240789 c.927T>C synonymous_variant 0.3
embC 4240819 c.957A>G synonymous_variant 0.2
embC 4240825 c.963G>A synonymous_variant 0.18
embC 4240831 c.969T>G synonymous_variant 0.2
embC 4240867 c.1005T>G synonymous_variant 0.17
embC 4240870 c.1008T>C synonymous_variant 0.17
embC 4240879 c.1017G>C synonymous_variant 0.17
embC 4240880 p.Ala340Thr missense_variant 0.17
embC 4240885 c.1023T>C synonymous_variant 0.15
embC 4240897 c.1035C>G synonymous_variant 0.18
embC 4240919 c.1057_1059delCTCinsTTG synonymous_variant 0.22
embC 4240945 c.1083T>C synonymous_variant 0.2
embC 4240951 c.1089C>G synonymous_variant 0.2
embC 4240954 p.Ile364Met missense_variant 0.2
embC 4240957 c.1095C>G synonymous_variant 0.2
embC 4240966 c.1104G>T synonymous_variant 0.22
embC 4240979 p.Thr373Gln missense_variant 0.22
embC 4240983 p.Ser374Asn missense_variant 0.22
embC 4240990 c.1128A>G synonymous_variant 0.25
embC 4240996 c.1134G>C synonymous_variant 0.29
embC 4241017 c.1155T>C synonymous_variant 0.29
embC 4241023 c.1161T>G synonymous_variant 0.29
embC 4241026 c.1164C>G synonymous_variant 0.29
embC 4241035 c.1173G>A synonymous_variant 0.33
embC 4241050 c.1188T>G synonymous_variant 0.33
embC 4241256 p.Arg465Thr missense_variant 1.0
embB 4245617 c.-897C>G upstream_gene_variant 0.2
embB 4245620 c.-894T>C upstream_gene_variant 0.2
embB 4245623 c.-891G>C upstream_gene_variant 0.2
embB 4245626 c.-888G>C upstream_gene_variant 0.2
embA 4245643 p.Ala804Val missense_variant 0.25
embA 4245648 p.Ile806Tyr missense_variant 0.25
embA 4245652 p.Thr807Ser missense_variant 0.25
embB 4245659 c.-855C>G upstream_gene_variant 0.25
embB 4245674 c.-840A>C upstream_gene_variant 0.25
embB 4245677 c.-837G>C upstream_gene_variant 0.25
embB 4245680 c.-834G>A upstream_gene_variant 0.22
embB 4245683 c.-831C>G upstream_gene_variant 0.2
embB 4245689 c.-825C>G upstream_gene_variant 0.22
embB 4245692 c.-822G>C upstream_gene_variant 0.22
embA 4245693 p.Ile821Val missense_variant 0.22
embB 4245701 c.-813G>C upstream_gene_variant 0.2
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.29
embA 4245820 p.Ser863Thr missense_variant 0.25
embB 4245830 c.-684G>C upstream_gene_variant 0.25
embB 4245845 c.-669T>G upstream_gene_variant 0.29
embB 4245848 c.-666C>G upstream_gene_variant 0.43
embB 4245860 c.-654C>G upstream_gene_variant 0.33
embA 4246449 p.Val1073Phe missense_variant 1.0
aftB 4268192 c.645G>C synonymous_variant 1.0