TB-Profiler result

Run: SRR18572456
Summary

Run ID: SRR18572456

Sample name:

Date: 03-04-2023 19:55:53

Number of reads: 5593599

Percentage reads mapped: 93.17

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 762879 p.Met1025Leu missense_variant 0.1
rpoC 763570 c.201G>C synonymous_variant 0.11
rpoC 763621 c.252C>G synonymous_variant 0.13
rpoC 763633 c.264T>C synonymous_variant 0.12
rpoC 763660 c.291T>G synonymous_variant 0.13
rpoC 763675 c.306C>G synonymous_variant 0.1
rpoC 763696 c.327T>C synonymous_variant 0.11
rpoC 764650 c.1281G>C synonymous_variant 0.11
rpoC 764665 c.1296C>G synonymous_variant 0.12
rpoC 764677 c.1308C>G synonymous_variant 0.14
rpoC 764681 p.Leu438Met missense_variant 0.15
rpoC 764706 p.Leu446Gln missense_variant 0.13
rpoC 764713 c.1344G>C synonymous_variant 0.12
rpoC 764731 c.1362G>C synonymous_variant 0.12
rpoC 764746 c.1377G>C synonymous_variant 0.1
fbiC 1305250 p.Arg774Gly missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.17
rrl 1473908 n.251C>A non_coding_transcript_exon_variant 0.18
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.12
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.11
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.11
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.11
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.11
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.12
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.13
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.14
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.17
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.18
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.12
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.13
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.14
rrl 1475300 n.1643G>A non_coding_transcript_exon_variant 0.12
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.18
rrl 1475757 n.2100_2101insG non_coding_transcript_exon_variant 0.2
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.2
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.2
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.2
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.22
rrl 1475768 n.2111G>T non_coding_transcript_exon_variant 0.2
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.22
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.25
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.18
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.18
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.11
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.11
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.19
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.12
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.22