Run ID: SRR29051386
Sample name:
Date: 2025-02-11T19:25:28.872656
Number of reads: 27818
Percentage reads mapped: 57.08
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.99 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| inhA | 1674507 | c.306G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674534 | c.333G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674540 | c.339C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674585 | c.384T>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674621 | c.420C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674651 | c.450C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674702 | c.501G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674703 | c.502_504delTTGinsCTC | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674726 | c.525G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674729 | c.528G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674742 | p.Lys181Gln | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674746 | p.Tyr182Phe | missense_variant | 1.0 | isoniazid | |
| ethionamide |
