Run ID: SRR29096290
Sample name:
Date: 2025-02-11T19:05:24.052987
Number of reads: 25838
Percentage reads mapped: 30.0
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 1.0 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155696 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155742 | p.Gly124Arg | missense_variant | 1.0 | isoniazid | |
| katG | 2155747 | p.Ala122Gly | missense_variant | 1.0 | isoniazid | |
| katG | 2155749 | c.363C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155752 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155764 | p.His116Glu | missense_variant | 1.0 | isoniazid | |
| katG | 2155769 | p.Ile115Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155770 | c.342C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155782 | c.330C>A | synonymous_variant | 1.0 | isoniazid | |
| lpqB | 3624614 | c.297A>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624635 | p.His92Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3624643 | p.Ile90Leu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624649 | c.262T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624650 | c.261G>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624656 | c.255C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624673 | p.Ala80Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624675 | p.Asn79Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624680 | c.231T>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624701 | c.210T>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624704 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624719 | c.192C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624725 | c.186G>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247511 | p.Tyr333Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4247527 | c.1014G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247536 | c.1023C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247555 | p.Leu348Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247578 | c.1065_1066insATCTGT | conservative_inframe_insertion | 1.0 | ethambutol | |
| embB | 4247581 | c.1069_1074delGCCGGG | conservative_inframe_deletion | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
