Run ID: SRR3675323
Sample name:
Date: 2024-03-25T17:10:53.295726
Number of reads: 72618
Percentage reads mapped: 28.8
Median coverage: 2.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 0.98 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.99 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
rpoB | 760514 | c.708C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.9 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.91 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 | streptomycin |