TB-Profiler result

Run: SRR3675557
Summary

Run ID: SRR3675557

Sample name:

Date: 04-04-2023 05:33:20

Number of reads: 19266

Percentage reads mapped: 3.63

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.62 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.93 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9304 p.Gly668Asp missense_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.67
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.67
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.75
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.75
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.75
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.8
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.8
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.8
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.8
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.8
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.8
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.8
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.8
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.8
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.8
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 1.0
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 1.0
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.71
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.85
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.85
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.62
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.85
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.23
rrs 1472669 n.824_825insTGGA non_coding_transcript_exon_variant 0.89
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.25
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.92
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.93
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.57
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.93
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 1.0
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.71
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrl 1475704 n.2047C>T non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 1.0
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 1.0
rrl 1475752 n.2095C>G non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>A non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>C non_coding_transcript_exon_variant 1.0
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 1.0
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 1.0
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 1.0
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 1.0
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 1.0
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.83
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.75
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.75
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.83
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.29
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.64
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.93
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.27
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.27
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.27
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.93
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.93
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.93
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.93
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.93
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.93
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.2
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.8
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.91
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.93
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.93
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.93
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.94
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.96
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.67
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.97
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.97
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.41
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.97
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.97
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.97
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.33
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 1.0
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.4
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 1.0
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 1.0
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.5
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0
rrl 1476574 n.2917A>T non_coding_transcript_exon_variant 0.5
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.5
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476594 n.2937C>G non_coding_transcript_exon_variant 1.0
rrl 1476603 n.2946G>C non_coding_transcript_exon_variant 1.0
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 1.0
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0