TB-Profiler result

Run: SRR5818453
Summary

Run ID: SRR5818453

Sample name:

Date: 04-04-2023 11:32:10

Number of reads: 392186

Percentage reads mapped: 99.49

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760094 c.288G>T synonymous_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.67
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.68
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.62
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.15
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.18
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.26
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.25
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.19
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.17
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.33
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.27
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.34
fabG1 1673770 p.Ala111Pro missense_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.36
ahpC 2726338 p.Val49Gly missense_variant 0.24
ahpC 2726341 p.Val50Gly missense_variant 0.22
gid 4407588 c.615A>G synonymous_variant 1.0