TB-Profiler result

Run: ERR4815419
Summary

Run ID: ERR4815419

Sample name:

Date: 01-04-2023 13:51:20

Number of reads: 2894243

Percentage reads mapped: 91.03

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.71 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8933 c.1632G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.11
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.29
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.1
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.21
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.12
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.28
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.33
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.33
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.68
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.72
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.75
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.77
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.8
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.82
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.83
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.84
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.82
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.82
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.46
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.42
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.38
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.28
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.26
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.28
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.27
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.28
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.25
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.29
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.46
rrs 1472706 n.861C>T non_coding_transcript_exon_variant 0.12
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.64
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.63
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.71
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.69
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.73
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.63
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.56
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.22
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.12
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.12
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.1
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474372 n.715C>T non_coding_transcript_exon_variant 0.25
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.22
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.17
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.15
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.14
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.14
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.24
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.12
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.12
rrl 1474535 n.878A>C non_coding_transcript_exon_variant 0.12
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.27
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.14
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.14
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.29
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.12
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.12
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.12
rrl 1476187 n.2530T>C non_coding_transcript_exon_variant 0.11
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.11
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.16
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0