TB-Profiler result

Run: ERR4817817
Summary

Run ID: ERR4817817

Sample name:

Date: 01-04-2023 15:12:48

Number of reads: 3815003

Percentage reads mapped: 83.5

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 778504 c.-24G>A upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781598 c.39G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472088 n.243T>A non_coding_transcript_exon_variant 0.29
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.33
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.5
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.55
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.55
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.65
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.65
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.79
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.76
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.76
rrs 1472251 n.406G>T non_coding_transcript_exon_variant 0.67
rrs 1472252 n.407G>A non_coding_transcript_exon_variant 0.67
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.67
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.67
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.67
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 1.0
rrs 1472714 n.869A>C non_coding_transcript_exon_variant 1.0
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.93
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.95
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.95
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.67
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.83
rrs 1473139 n.1294T>C non_coding_transcript_exon_variant 0.3
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.3
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.3
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.5
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.43
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.46
rrs 1473191 n.1346C>T non_coding_transcript_exon_variant 0.36
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.43
rrs 1473198 n.1354delC non_coding_transcript_exon_variant 0.43
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.43
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.5
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.46
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476791 n.3134C>A non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 0.99
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568857 c.-178C>T upstream_gene_variant 1.0
panD 4044023 c.259C>T synonymous_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0