TB-Profiler result

Run: ERR4831068
Summary

Run ID: ERR4831068

Sample name:

Date: 01-04-2023 20:39:41

Number of reads: 2558529

Percentage reads mapped: 99.39

Strain: lineage4.1;lineage3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.93
lineage4 Euro-American LAM;T;S;X;H None 0.07
lineage4.1 Euro-American T;X;H None 0.05
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5339 p.Ile34Val missense_variant 0.9
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.95
rpoB 759746 c.-61C>T upstream_gene_variant 0.88
rpoC 762434 c.-936T>G upstream_gene_variant 0.94
rpoC 763031 c.-339T>C upstream_gene_variant 0.87
mmpL5 775639 p.Ile948Val missense_variant 0.99
mmpL5 776100 p.Thr794Ile missense_variant 0.93
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472866 n.1021C>T non_coding_transcript_exon_variant 0.92
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.92
PPE35 2167926 p.Leu896Ser missense_variant 0.96
PPE35 2170065 p.Ala183Gly missense_variant 0.24
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 0.96
pncA 2289365 c.-125delC upstream_gene_variant 0.95
kasA 2518076 c.-39C>T upstream_gene_variant 0.12
ahpC 2726105 c.-88G>A upstream_gene_variant 0.94
ribD 2986835 c.-4G>A upstream_gene_variant 0.92
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.33
fbiD 3339744 c.627A>T synonymous_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878613 c.-106A>C upstream_gene_variant 0.2
rpoA 3878637 c.-130G>C upstream_gene_variant 0.3
rpoA 3878640 c.-133G>C upstream_gene_variant 0.12
panD 4044219 p.His21Gln missense_variant 0.95
embC 4242075 p.Arg738Gln missense_variant 0.96
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.57
embB 4248324 p.Ala604Gly missense_variant 0.22
embB 4248575 p.Phe688Val missense_variant 0.95
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.9