TB-Profiler result

Run: ERR7821140
Summary

Run ID: ERR7821140

Sample name:

Date: 02-04-2023 06:22:00

Number of reads: 2041103

Percentage reads mapped: 75.9

Strain: lineage2.2.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
lineage2.2.1.1 East-Asian (Beijing) Beijing-RD150 RD105;RD207;RD181;RD150 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.97
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.18
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302818 c.-113G>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.17
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.16
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.16
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.14
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.25
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.29
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.32
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.38
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.32
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.32
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.35
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.38
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.33
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.33
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.31
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.25
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.25
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.27
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.38
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.38
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.38
rrs 1472544 n.699C>G non_coding_transcript_exon_variant 0.29
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.22
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.45
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.5
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.5
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.45
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.45
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.54
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.55
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.45
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.4
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.15
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.15
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.25
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.33
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.12
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.25
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.12
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.41
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.16
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.14
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.38
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.32
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.42
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.32
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.28
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.28
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.22
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.2
rrs 1473001 n.1156G>C non_coding_transcript_exon_variant 0.17
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.24
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.14
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 1.0
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 1.0
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 1.0
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.67
rrl 1475760 n.2103C>G non_coding_transcript_exon_variant 0.67
rrl 1475763 n.2106C>A non_coding_transcript_exon_variant 0.67
rrl 1475767 n.2110G>C non_coding_transcript_exon_variant 0.5
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.75
rrl 1475775 n.2118G>C non_coding_transcript_exon_variant 0.75
rrl 1475776 n.2119G>A non_coding_transcript_exon_variant 0.75
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.75
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.67
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.67
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.67
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.71
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.62
rrl 1475843 n.2186G>A non_coding_transcript_exon_variant 0.5
rrl 1475853 n.2196C>T non_coding_transcript_exon_variant 0.29
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.25
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.38
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.38
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.55
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.5
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.55
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.6
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.55
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.5
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.46
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.5
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.5
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.6
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.23
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.45
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.5
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.74
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.73
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.76
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.75
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.75
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.77
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.76
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.7
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.62
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.61
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.55
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.55
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.55
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.57
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.57
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.6
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.6
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.61
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.59
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.47
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.44
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.14
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.42
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.32
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.29
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.19
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.2
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223014 p.Tyr51Asn missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714846 p.Val163Ile missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
rpoA 3878336 p.Gly58Arg missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.22
embB 4248115 c.1602C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0